Recombinant factor VIIa as an adjunct in nonoperative management of solid organ injuries in children

Journal of Pediatric Surgery

Volumn 43, Issue 1, 2008, Pages 195-199

  Vick, Laura R ^a   Islam, Saleem ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Blunt abdominal trauma; Pediatric trauma, nonoperative trauma; Recombinant factor VIIa

Indexed keywords

RECOMBINANT BLOOD CLOTTING FACTOR 7A; VITAMIN K GROUP;

ABDOMINAL BLEEDING; ADOLESCENT; ARTICLE; CHILDHOOD INJURY; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONSERVATIVE TREATMENT; CONTROLLED STUDY; ERYTHROCYTE TRANSFUSION; FEMALE; HEART RATE; HEMATOCRIT; HUMAN; INJURY SEVERITY; MALE; MEDICAL RECORD REVIEW; ORGAN INJURY; PRIORITY JOURNAL; SCHOOL CHILD; SINGLE DRUG DOSE; SUBARACHNOID HEMORRHAGE; THROMBOEMBOLISM; TREATMENT OUTCOME;

ABDOMINAL INJURIES; ADOLESCENT; BLOOD TRANSFUSION; CHILD; COHORT STUDIES; COMBINED MODALITY THERAPY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; EMERGENCY SERVICE, HOSPITAL; FACTOR VIIA; FEMALE; FOLLOW-UP STUDIES; HUMANS; INJURY SEVERITY SCORE; KIDNEY; LIVER; MALE; RECOMBINANT PROTEINS; RETROSPECTIVE STUDIES; SPLEEN; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME; WOUNDS, NONPENETRATING;

EID: 38149005445     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2007.09.044     Document Type: Article

References (23)

1. Nance M., Holmes J., and Wiebe D. Timeline to operative intervention for solid organ injuries in children. J Trauma 61 (2006) 1389-1392
2. Puapong D., Brown C., Katz M., et al. Angiography and the pediatric trauma patient: a 10-year review. J Pediatr Surg 41 11 (2006) 1859-1863
3. Kenet G., Walden R., Eldad A., et al. Treatment of traumatic bleeding with recombinant factor VIIa. Lancet 354 (1999) 1879
4. Stein D.M., and Dutton R.P. Uses of recombinant factor VIIa in trauma. Curr Opin Crit Care 10 (2004) 520-528
5. Khan A.Z., Parry J.M., Crowley W.F., et al. Recombinant factor VIIa for the treatment of severe postoperative and traumatic hemorrhage. Am J Surg 189 (2005) 331-334
6. Rizoli S., Nascimento B., Osman F., et al. Recombinant activated coagulation factor VII and bleeding trauma patients. J Trauma 61 (2006) 1419-1425
7. Mohr A., Holcomb J., Dutton R., et al. Recombinant activated factor VIIa and hemostasis in critical care: a focus on trauma. Critical Care 9 Suppl 5 (2005) S37-S42
8. Harrison T., Laskosky J., Jazaeri O., et al. "Low-dose" recombinant activated factor VII results in less blood and blood product use in traumatic hemorrhage. J Trauma 59 (2005) 150-154
9. Boffard K., Riou B., Warren B., et al. Recombinant factor VIIa as adjunctive therapy for bleeding control in severely injured trauma patients: two parallel randomized, placebo-controlled, double-blind clinical trials. J Trauma 59 (2005) 8-18
10. Rizoli S., Boffard K., Riou B., et al. Recombinant activated factor VII as an adjunctive therapy for bleeding control in severe trauma patients with coagulopathy: subgroup analysis from two randomized trials. Critical Care 10 (2006) R178
11. Kulkarni R., Daneshmand A., Guertin S., et al. Successful use of activated recombinant factor VII in traumatic liver injuries in children. J Trauma 56 (2004) 1348-1352
12. Chino J., Paolini D., Tran A., et al. Recombinant factor VIIa as an adjunct to packing for liver injury with hepatic venous disruption. Am Surg 71 (2005) 595-597
13. Arkin S., Cooper H., Hutter J., et al. Activated recombinant human coagulation factor VII therapy for intracranial hemorrhage in patients with hemophilia A or B with inhibitors: results of the Novoseven emergency use program. Haemostasis 28 (1998) 93-98
14. Hedner U., and Erhardtsen E. Potential role for rFVIIA in transfusion medicine. Transfusion 42 (2002) 114-124
15. Mathew P. The use of rFVIIa in non-haemophilia bleeding conditions in paediatrics. Thromb Haemost 92 (2004) 738-746
16. Verrijckt A., Proulx F., Morneau S., et al. Activated recombinant factor VII for refractory bleeding during extra corporeal membrane oxygenation. J Thorac Cardiovasc Surg 127 (2004) 1812-1813
17. Greisen G., and Andreasen R.B. Recombinant factor VIIa in preterm neonates with prolonged prothrombin time. Blood Coag Fibrinol 14 (2003) 117-120
18. Brady K., Easley R., and Tobias J. Recombinant activated factor VII (rFVIIa) treatment in infants with hemorrhage. Paediatr Anaesth 16 10 (2006) 1042-1046
19. O'Connel K.A., Wood J.J., Wise R.P., et al. Thromboembolic adverse events after use of recombinant human coagulation factor VIIa. JAMA 295 3 (2006) 293-298
20. Como J., Dutton R., Scalea T., et al. Blood transfusion rates in the care of acute trauma. Transfusion 44 (2004) 809-813
21. Gong M., Thompson B., Williams P., et al. Clinical predictors of and mortality in acute respiratory distress syndrome: potential role of red cell transfusion. Crit Care Med 33 (2005) 1191-1198
22. Morris S., Ridley S., Munro V., et al. Cost effectiveness of recombinant activated factor VII for the control of bleeding in patients with severe blunt trauma injuries in the United Kingdom. Anaesthesia 62 (2007) 43-52
23. Earnshaw S.R., Joshi A.V., Wilson M.R., et al. Cost-effectiveness of recombinant activated factor VII in the treatment of intracerebral hemorrhage. Stroke 37 (2006) 2751-2758