Comparison of continuous subcutaneous insulin infusion (CSII) and multiple daily injections (MDI) in paediatric Type 1 diabetes: A multicentre matched-pair cohort analysis over 3 years

Diabetic Medicine

Volumn 25, Issue 1, 2008, Pages 80-85

  Jakisch, B I ^a,h   Wagner, V M ^b   Heidtmann, B ^a   Lepler, R ^a   Holterhus, P M ^c   Kapellen, T M ^d   Vogel, C ^e   Rosenbauer, J ^f   Holl, R W ^g  

^a Catholic Children's Hospital Wilhelmstift   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^d UNIVERSITY OF LEIPZIG   (Germany)

^e Hospital Chemnitz   (Germany)

^f HEINRICH HEINE UNIVERSITY   (Germany)

^g UNIVERSITY OF ULM   (Germany)

^h Catholic Children's Hospital Wilhelmstift   (Germany)

Author keywords

Children; CSII; HbA1c; Intensive therapy; Type 1 diabetes

Indexed keywords

HEMOGLOBIN A1C; INSULIN;

ARTICLE; BODY MASS; CLINICAL TRIAL; CONTINUOUS INFUSION; CONTROLLED STUDY; DIABETIC KETOACIDOSIS; DISEASE SEVERITY; FEMALE; FOLLOW UP; GLYCEMIC CONTROL; HUMAN; HYPOGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OUTCOME ASSESSMENT; PATIENT CARE;

ADOLESCENT; BLOOD GLUCOSE; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DIABETES MELLITUS, TYPE 1; DIABETIC KETOACIDOSIS; DRUG ADMINISTRATION SCHEDULE; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPOGLYCEMIA; HYPOGLYCEMIC AGENTS; INFANT; INFANT, NEWBORN; INJECTIONS; INSULIN; INSULIN INFUSION SYSTEMS; MALE; TREATMENT OUTCOME;

EID: 38049185089     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/j.1464-5491.2007.02311.x     Document Type: Article

References (30)

1. Tamborlane WV, Sherwin RS, Genel M, Felig P. Reduction to normal of plasma glucose in juvenile diabetes by subcutaneous administration of insulin with a portable infusion pump. N Engl J Med 1979 300 : 573 578.
2. Heidtmann B, Hilgard D, Kapellen T, Schumacher A, Lepler R, Schober E et al. Insulin pump therapy in children younger than 6 years: comparison of metabolic parameters before and 6 as well as 12 months after initiation of pump therapy. Diabetologie und Stoffwechsel 2007 2 : 33 37
3. Holder M, Ludwig-Seibold C, Lilienthal E, Ziegler R, Heidtmann B, Holl RW. Für die DPV-wiss-initiative: trends in insulin pump therapy in children, adolescents and young adults with Type-1-diabetes between 1995 and 2006: results from the DPV-initiative. Diabetologie und Stoffwechsel 2007 2 : 169 174
4. Litton J, Rice A, Friedman N, Oden J, Lee MM, Freemark M. Insulin pump therapy in toddlers and preschool children with type 1 diabetes mellitus. J Pediatr 2002 141 : 490 495.
5. Weissberg-Benchell J, Antisdel-Lomaglio J, Seshadri R. Insulin pump therapy: a meta-analysis. Diabetes Care 2003 26 : 1079 1087.
6. Wilson DM, Buckingham BA, Kunselman EL, Sullivan MM, Paguntalan HU, Gitelman SE. A two-centre randomised controlled feasibility trial of insulin pump therapy in young children with diabetes. Diabetes Care 2005 28 : 15 19.
7. Doyle EA, Weinzimer SA, Steffen AT, Ahern JA, Vincent M, Tamborlane WV. A randomised, prospective trial comparing the efficacy of continuous subcutaneous insulin infusion with multiple daily injections using insulin glargine. Diabetes Care 2004 27 : 1554 1558.
8. Fox LA, Buckloh LM, Smith SD, Wysocki T, Mauras N. A randomised controlled trial of insulin pump therapy in young children with type 1 diabetes. Diabetes Care 2005 28 : 1277 1281.
9. DiMeglio LA, Pottorff TM, Boyd SR, France L, Fineberg N, Eugster EA. A randomised, controlled study of insulin pump therapy in diabetic preschoolers. J Pediatr 2004 145 : 380 384.
10. Weintrob N, Benzaquen H, Galatzer A, Shalitin S, Lazar L, Fayman G et al. Comparison of continuous subcutaneous insulin infusion and multiple daily injection regimens in children with type 1 diabetes: a randomised open crossover trial. Paediatrics 2003 112 (3 Pt 1 559 564.
11. Kordonouri O, Hartmann R, Lauterborn R, Barnekow C, Hoeffe J, Deiss D. Age-specific advantages of continuous subcutaneous insulin infusion as compared with multiple daily injections in paediatric patients: one-year follow-up comparison by matched-pair analysis. Diabetes Care 2006 29 : 133 134.
12. Holl RW, Grabert M, Hecker W, Klinghammer A, Renner C, Schweiggert F et al. Quality control in health care of children and adolescents with diabetes: an external comparison in 23 centres of paediatric diabetology. Diabet Stoffw 1997 6 : 83 90.
13. Kapellen TM, Heidtmann B, Bachmann J, Ziegler R, Grabert M, Holl RW. For the DPV-science-initiative and the German working group for insulin pump treatment in pediatric patients. Indications for insulin pump therapy in different age groups - an analysis of 1567 children and adolescents. Diabet Med 2007 8 : 836 842.
14. DCCT Research Group. Feasibility of centralized measurements of glycated hemoglobin in the Diabetes Control and Complications Trial: a multi-centre study. Clin Chem 1987 33 : 2267 2271.
15. International Society for Paediatric Adolescent Diabetes (ISPAD, 2000). Consensus guidelines 2000. In Swift PGF ed. Publ. Medforum. Zeist, theNetherlands : 2000. Available at http://www.diabetesguidelines.com/health/ dwk/pro/guidelines/ISPAD/13-03.asp Last accessed 5 December 2007.
16. Kromeyer-Hauschild K, Wabitsch M, Kunze D, Geller F, Geiß HC, Hesse V et al. Percentiles of body mass index in children and adolescents evaluated from different regional German studies. Monatsschrift Kinderheilkunde 2001 149 : 807 818.
17. Cole TJ, Green PJ. Smoothing reference centile curves: the LMS method and penalized likelihood. Stat Med 1992 11 : 1305 1319.
18. Littell RC, Milliken GA, Stroup WW, Wolfinger RD, Schabenberger O. SAS for Mixed Models, 2nd edn. Cary, NC : SAS Press, 2006.
19. Dmitrienko A, Molenbergs G, Chuang-Stein C, Offen W. Analysis of Clinical Trials using SAS, Cary, NC : SAS Press, 2005.
20. Plotnick LP, Clark LM, Brancati FL, Erlinger T. Safety and effectiveness of insulin pump therapy in children and adolescents with type 1 diabetes. Diabetes Care 2003 26 : 1142 1146.
21. Weinzimer SA, Ahern JH, Doyle EA, Vincent MR, Dziura J, Steffen AT et al. Persistence of benefits of continuous subcutaneous insulin infusion in very young children with type 1 diabetes: a follow-up report. Paediatrics 2004 114 : 1601 1605.
22. Colquitt JL, Green C, Sidhu MK, Hartwell D, Waugh N. Clinical and cost-effectiveness of continuous subcutaneous insulin infusion for diabetes. Health Technol Assess 2004 8 : iii, 1 171 (Review).
23. Diabetes Control Complications Trial Research Group. Effect of intensive diabetes treatment on the development and progression of long-term complications in adolescents with insulin-dependent diabetes mellitus: Diabetes Control and Complications Trial. J Pediatr 1994 125 : 177 188.
24. Mortensen HB, Hougaard P. Comparison of metabolic control in a cross-sectional study of 2873 children and adolescents with IDDM from 18 countries. The Hvidore Study Group on Childhood Diabetes. Diabetes Care. 1997 20 : 714 720. Erratum in: Diabetes Care 1997; 20: 1216.
25. Wagner VM, Grabert M, Holl RW. Severe hypoglycaemia, metabolic control and diabetes management in children with type 1 diabetes in the decade after the Diabetes Control and Complications Trial-a large-scale multicentre study. Eur J Pediatr 2005 164 : 73 79
26. Hanas R, Ludvigsson J. Hypoglycaemia and ketoacidosis with insulin pump therapy in children and adolescents. Pediatr Diabetes 2006 7 (Suppl 4 32 38.
27. Donaghue KC, Fung ATW, Hing S, Fairchild J, King J, Chan A. The effect of prepubertal diabetes duration on diabetes: microvascular complications in early and late adolescence. Diabetes Care 1997 20 : 77 80.
28. Scuffham P, Carr L. The cost-effectiveness of continuous subcutaneous insulin infusion compared with multiple daily injections for the management of diabetes. Diabet Med 2003 20 : 586 593.
29. Roze S, Valentine WJ, Zakrzewska KE, Palmer AJ. Health-economic comparison of continuous subcutaneous insulin infusion with multiple daily injection for the treatment of Type 1 diabetes in the UK. Diabet Med 2005 22 : 1239 1245.
30. Barnard KD, Lloyd CE, Skinner TC. Systematic literature review: quality of life associated with insulin pump use in Type 1 diabetes. Diabet Med 2007 24 : 607 617.