-
1
-
-
11144358391
-
Dementia: the leading predictor of death after age 85-the Cache County Study
-
Tschanz J.T., Corcoran C., Skoog I., Khachaturian A.S., Herrick K.M., Hayden K.L.M., et al. Dementia: the leading predictor of death after age 85-the Cache County Study. Neurology 62 (2004) 1156-1162
-
(2004)
Neurology
, vol.62
, pp. 1156-1162
-
-
Tschanz, J.T.1
Corcoran, C.2
Skoog, I.3
Khachaturian, A.S.4
Herrick, K.M.5
Hayden, K.L.M.6
-
2
-
-
0031721424
-
Seven-year survival rate after age 85 years: relation to Alzheimer disease and vascular dementia
-
Aevarsson O., Svanborg A., and Skoog I. Seven-year survival rate after age 85 years: relation to Alzheimer disease and vascular dementia. Arch Neurol 55 (1998) 1226-1232
-
(1998)
Arch Neurol
, vol.55
, pp. 1226-1232
-
-
Aevarsson, O.1
Svanborg, A.2
Skoog, I.3
-
3
-
-
0014316032
-
The field trial: some thoughts on the indispensable ordeal
-
Fredrickson D.S. The field trial: some thoughts on the indispensable ordeal. Bull NY Acad Med 44 (1968) 985-993
-
(1968)
Bull NY Acad Med
, vol.44
, pp. 985-993
-
-
Fredrickson, D.S.1
-
5
-
-
0035971814
-
Estimation of gender bias in clinical trials
-
Meinert C.L., and Gilpin A.K. Estimation of gender bias in clinical trials. Stat Med 20 (2000) 1153-1164
-
(2000)
Stat Med
, vol.20
, pp. 1153-1164
-
-
Meinert, C.L.1
Gilpin, A.K.2
-
6
-
-
0036174553
-
Double placebo design in a prevention trial for Alzheimer's disease
-
ADAPT Research Group
-
Martin K.M., Meinert C.L., Breitner J.C.S., and ADAPT Research Group. Double placebo design in a prevention trial for Alzheimer's disease. Controlled Clin Trials 23 (2002) 93-99
-
(2002)
Controlled Clin Trials
, vol.23
, pp. 93-99
-
-
Martin, K.M.1
Meinert, C.L.2
Breitner, J.C.S.3
-
7
-
-
20144365496
-
Investigators: cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
-
Solomon S.D., McMurray J.J.V., Pfeffer M.A., Wittes J., Fowler R., Finn P., et al. Investigators: cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med 352 (2005) 1071-1080
-
(2005)
N Engl J Med
, vol.352
, pp. 1071-1080
-
-
Solomon, S.D.1
McMurray, J.J.V.2
Pfeffer, M.A.3
Wittes, J.4
Fowler, R.5
Finn, P.6
-
8
-
-
33847373072
-
Cardiovascular and cerebrovascular results from the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT)
-
ADAPT Research Group
-
ADAPT Research Group. Cardiovascular and cerebrovascular results from the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT). PLoS Clin Trials 1 (2006) e33
-
(2006)
PLoS Clin Trials
, vol.1
-
-
-
10
-
-
4544350756
-
Mild cognitive impairment - Beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment
-
Winblad B., Palmer K., Kivipelto M., Jelic V., Fratiglioni L., Wahlund L.O., et al. Mild cognitive impairment - Beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment. J Inter Med 256 (2004) 240-246
-
(2004)
J Inter Med
, vol.256
, pp. 240-246
-
-
Winblad, B.1
Palmer, K.2
Kivipelto, M.3
Jelic, V.4
Fratiglioni, L.5
Wahlund, L.O.6
-
11
-
-
0032988610
-
Mild cognitive impairment: clinical characterization and outcome (erratum in Arch Neurol 1999;56:760)
-
Petersen R.C., Smith G.E., Waring S.C., Ivnik R.J., Tangalos E.G., and Kokmen E. Mild cognitive impairment: clinical characterization and outcome (erratum in Arch Neurol 1999;56:760). Arch Neurol 56 (1999) 303-308
-
(1999)
Arch Neurol
, vol.56
, pp. 303-308
-
-
Petersen, R.C.1
Smith, G.E.2
Waring, S.C.3
Ivnik, R.J.4
Tangalos, E.G.5
Kokmen, E.6
-
12
-
-
20344381835
-
Vitamin E and donepezil for the treatment of mild cognitive impairment
-
Petersen R., Thomas R.G., Grundman M., Bennett D., Doody R., Ferris S., et al. Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med 352 (2005) 2379-2388
-
(2005)
N Engl J Med
, vol.352
, pp. 2379-2388
-
-
Petersen, R.1
Thomas, R.G.2
Grundman, M.3
Bennett, D.4
Doody, R.5
Ferris, S.6
-
13
-
-
21144447586
-
A randomized, doubleblind, study of rofecoxib in patients with mild cognitive impairment
-
Thal L.J., Ferris S.H., Kirby L., Block G.A., Lines C.R., Yuen E., et al. A randomized, doubleblind, study of rofecoxib in patients with mild cognitive impairment. Neuropsychopharmacology 30 (2005) 1204-1215
-
(2005)
Neuropsychopharmacology
, vol.30
, pp. 1204-1215
-
-
Thal, L.J.1
Ferris, S.H.2
Kirby, L.3
Block, G.A.4
Lines, C.R.5
Yuen, E.6
-
14
-
-
0035936004
-
Nonsteroidal anti-inflammatory drugs and the risk of Alzheimer's disease
-
In 't Veld B., Ruitenberg A., Hofman A., Launer L.J., van Duijn C.M., Stijnen T., et al. Nonsteroidal anti-inflammatory drugs and the risk of Alzheimer's disease. N Engl J Med 345 (2001) 1515-1521
-
(2001)
N Engl J Med
, vol.345
, pp. 1515-1521
-
-
In 't Veld, B.1
Ruitenberg, A.2
Hofman, A.3
Launer, L.J.4
van Duijn, C.M.5
Stijnen, T.6
-
15
-
-
0037167542
-
Reduced incidence of AD with NSAID but not H2 receptor antagonists: the Cache County Study
-
Zandi P.P., Anthony J., Hayden K.M., Mehta K., Mayer L., Breitner J.C., et al. Reduced incidence of AD with NSAID but not H2 receptor antagonists: the Cache County Study. Neurology 59 (2002) 880-886
-
(2002)
Neurology
, vol.59
, pp. 880-886
-
-
Zandi, P.P.1
Anthony, J.2
Hayden, K.M.3
Mehta, K.4
Mayer, L.5
Breitner, J.C.6
-
16
-
-
34249058674
-
Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial
-
ADAPT Research Group
-
ADAPT Research Group. Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial. Neurology 68 (2007) 1800-1808
-
(2007)
Neurology
, vol.68
, pp. 1800-1808
-
-
-
17
-
-
0017042882
-
Design and analysis of randomized clinical trials requiring prolonged observation of each patient: I-introduction and design
-
Peto R., Pike M.C., and Armitage P. Design and analysis of randomized clinical trials requiring prolonged observation of each patient: I-introduction and design. Br J Cancer 34 (1976) 585-612
-
(1976)
Br J Cancer
, vol.34
, pp. 585-612
-
-
Peto, R.1
Pike, M.C.2
Armitage, P.3
-
18
-
-
0028831227
-
Large-scale randomized evidence: large, simple trials and overview of trials
-
Peto R., Collins R., and Gray R. Large-scale randomized evidence: large, simple trials and overview of trials. J Clin Epidemiol 48 (1995) 23-40
-
(1995)
J Clin Epidemiol
, vol.48
, pp. 23-40
-
-
Peto, R.1
Collins, R.2
Gray, R.3
-
19
-
-
0024406369
-
Final report on the aspirin component of the ongoing Physicians' Health Study
-
Physicians' Health Study Research Group Steering Committee
-
Physicians' Health Study Research Group Steering Committee. Final report on the aspirin component of the ongoing Physicians' Health Study. N Engl J Med 321 (1989) 129-135
-
(1989)
N Engl J Med
, vol.321
, pp. 129-135
-
-
-
20
-
-
0033619959
-
Underrepresentation of patients 65 years of age or older in cancer-treatment trials
-
Hutchins L.F., Unger J.M., Crowley J.J., Coltman C.A., and Albain K.S. Underrepresentation of patients 65 years of age or older in cancer-treatment trials. N Engl J Med 341 (1999) 2061-2067
-
(1999)
N Engl J Med
, vol.341
, pp. 2061-2067
-
-
Hutchins, L.F.1
Unger, J.M.2
Crowley, J.J.3
Coltman, C.A.4
Albain, K.S.5
-
21
-
-
26044482707
-
Under-representation of the elderly in clinical trials
-
Rehman H.U. Under-representation of the elderly in clinical trials. Eur J Intern Med 16 (2005) 385-386
-
(2005)
Eur J Intern Med
, vol.16
, pp. 385-386
-
-
Rehman, H.U.1
-
22
-
-
0033326072
-
Are the elderly underrepresnted in clinical drug trials
-
Schmucker D.L., and Vesell E.S. Are the elderly underrepresnted in clinical drug trials. J Clin Pharmacol 39 (1999) 1103-1108
-
(1999)
J Clin Pharmacol
, vol.39
, pp. 1103-1108
-
-
Schmucker, D.L.1
Vesell, E.S.2
-
23
-
-
28044442370
-
The limitations of "vulnerability" as a protection for human research participants
-
Levine C., Faden R., Grady C., Hammerschmidt D., Eckenwiler L., Surgarman J., et al. The limitations of "vulnerability" as a protection for human research participants. Am J Bioethics 4 (2004) 44-49
-
(2004)
Am J Bioethics
, vol.4
, pp. 44-49
-
-
Levine, C.1
Faden, R.2
Grady, C.3
Hammerschmidt, D.4
Eckenwiler, L.5
Surgarman, J.6
-
25
-
-
0023463379
-
Recruitment of participants for the Multiple Risk Factor Intervention Trial (MRFIT)
-
MRFIT Research Group
-
Neaton J.D., Grimm R.H., Cutler J.A., and MRFIT Research Group. Recruitment of participants for the Multiple Risk Factor Intervention Trial (MRFIT). Control Clin Trials 8 (1987) 41S-53S
-
(1987)
Control Clin Trials
, vol.8
-
-
Neaton, J.D.1
Grimm, R.H.2
Cutler, J.A.3
-
26
-
-
0013488890
-
The Hypertension Prevention Trial (HPT): design, methods, and baseline results
-
Hypertension Prevention Trial Research Group
-
Hypertension Prevention Trial Research Group. The Hypertension Prevention Trial (HPT): design, methods, and baseline results. Control Clin Trials 10 Suppl (1989) 1S-117S
-
(1989)
Control Clin Trials
, vol.10
, Issue.SUPPL
-
-
-
27
-
-
0015593704
-
The Coronary Drug Project: design, methods, and baseline results
-
Coronary Drug Project Research Group
-
Coronary Drug Project Research Group. The Coronary Drug Project: design, methods, and baseline results. Circulation 47 Suppl 1 (1979) I-1-I-50
-
(1979)
Circulation
, vol.47
, Issue.SUPPL. 1
-
-
-
28
-
-
0023480576
-
Program on Surgical Control of the Hyperlipidemias (POSCH): recruitment experience
-
Buckwald H., Matts J.P., Hansen B.J., Long J.M., and Fitch L.L. Program on Surgical Control of the Hyperlipidemias (POSCH): recruitment experience. Control Clin Trials 8 Suppl 4 (1987) 94S-104S
-
(1987)
Control Clin Trials
, vol.8
, Issue.SUPPL. 4
-
-
Buckwald, H.1
Matts, J.P.2
Hansen, B.J.3
Long, J.M.4
Fitch, L.L.5
-
29
-
-
0024815041
-
Program on the Surgical Control of the Hyperlipidemias (POSCH): design and methodology. POSCH Group
-
Buckwald H., Matts J.P., Fitch L.L., Varco R.L., Campbell G.S., Pearce M., et al. Program on the Surgical Control of the Hyperlipidemias (POSCH): design and methodology. POSCH Group. J Clin Epidemiol 42 (1989) 1111-1127
-
(1989)
J Clin Epidemiol
, vol.42
, pp. 1111-1127
-
-
Buckwald, H.1
Matts, J.P.2
Fitch, L.L.3
Varco, R.L.4
Campbell, G.S.5
Pearce, M.6
-
30
-
-
0037317248
-
Familial patterns of risk in very late-onset Alzheimer disease
-
Silverman J.M., Smith C.J., Marin D.B., Mohs R.C., and Propper C.B. Familial patterns of risk in very late-onset Alzheimer disease. Arch Gen Psychiatry 60 (2003) 190-197
-
(2003)
Arch Gen Psychiatry
, vol.60
, pp. 190-197
-
-
Silverman, J.M.1
Smith, C.J.2
Marin, D.B.3
Mohs, R.C.4
Propper, C.B.5
-
31
-
-
0019976346
-
Multiple Risk Factor Intervention Trial: risk factor changes and mortality results
-
Multiple Risk Factor Intervention Trial Research Group
-
Multiple Risk Factor Intervention Trial Research Group. Multiple Risk Factor Intervention Trial: risk factor changes and mortality results. JAMA 248 (1982) 1445-1477
-
(1982)
JAMA
, vol.248
, pp. 1445-1477
-
-
-
32
-
-
0016630250
-
Clofibrate and niacin in coronary heart disease
-
Coronary Drug Project Research Group
-
Coronary Drug Project Research Group. Clofibrate and niacin in coronary heart disease. JAMA 231 (1975) 360-381
-
(1975)
JAMA
, vol.231
, pp. 360-381
-
-
-
33
-
-
0018579580
-
Five-year findings of the Hypertension Detection and Follow-Up Program: I-reduction in mortality of persons with high blood pressure, including mild hypertension
-
Hypertension Detection and Follow-Up Program Cooperative Group
-
Hypertension Detection and Follow-Up Program Cooperative Group. Five-year findings of the Hypertension Detection and Follow-Up Program: I-reduction in mortality of persons with high blood pressure, including mild hypertension. JAMA 242 (1979) 2562-2571
-
(1979)
JAMA
, vol.242
, pp. 2562-2571
-
-
-
34
-
-
0025831464
-
Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension: final results of the Systolic Hypertension in the Elderly Program (SHEP)
-
SHEP Cooperative Research Group
-
SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension: final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA 265 (1991) 3255-3294
-
(1991)
JAMA
, vol.265
, pp. 3255-3294
-
-
-
35
-
-
0037125379
-
Risks and benefits of estrogen plus progestin in healthy postmenopausal women
-
Writing Group for the Women's Health Initiative Investigators
-
Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women. JAMA 288 (2002) 321-333
-
(2002)
JAMA
, vol.288
, pp. 321-333
-
-
-
36
-
-
1842867053
-
Effects of conjugated estrogen in postmenopausal women with hysterectomy
-
The Women's Health Initiative Steering Committee
-
The Women's Health Initiative Steering Committee. Effects of conjugated estrogen in postmenopausal women with hysterectomy. JAMA 291 (2004) 1701-1712
-
(2004)
JAMA
, vol.291
, pp. 1701-1712
-
-
-
37
-
-
0000559926
-
A study of the effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes: I-design, methods, and baseline characteristics
-
University Group Diabetes Program Research Group
-
University Group Diabetes Program Research Group. A study of the effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes: I-design, methods, and baseline characteristics. Diabetes 19 Suppl 2 (1970) 747-783
-
(1970)
Diabetes
, vol.19
, Issue.SUPPL. 2
, pp. 747-783
-
-
-
38
-
-
38049181221
-
The case against "firewalls" in academic coordinating centers
-
Martin B.K., and Meinert C.L. The case against "firewalls" in academic coordinating centers. Control Clin Trials 23 (2003) 91s
-
(2003)
Control Clin Trials
, vol.23
-
-
Martin, B.K.1
Meinert, C.L.2
-
39
-
-
0010607277
-
The effect of vitamin E and beta carotene on the incidence of lung cancers and other cancers in male smokers
-
Beta Carotene Cancer Prevention Study Group
-
Beta Carotene Cancer Prevention Study Group. The effect of vitamin E and beta carotene on the incidence of lung cancers and other cancers in male smokers. N Engl J Med 330 (1994) 1029-1035
-
(1994)
N Engl J Med
, vol.330
, pp. 1029-1035
-
-
-
40
-
-
0037306675
-
Stopping the active intervention: CARET
-
Bowen D.J., Thornquist M., Anderson K., Barnett M., Powell C., Goodman G., et al. Stopping the active intervention: CARET. Control Clin Trials 24 (2003) 39-50
-
(2003)
Control Clin Trials
, vol.24
, pp. 39-50
-
-
Bowen, D.J.1
Thornquist, M.2
Anderson, K.3
Barnett, M.4
Powell, C.5
Goodman, G.6
|