Monte Carlo determination of radiation-induced cancer risks for prostate patients undergoing intensity-modulated radiation therapy

Journal of Applied Clinical Medical Physics

Volumn 8, Issue 4, 2007, Pages 14-27

  Stathakis, Sotirios ^a,b   Li, Jinsheng ^b   Ma, Charlie C M ^b  

^a University of Texas Health Science Center at San Antonio   (United States)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

IMRT; Prostate radiation therapy; Secondary malignancies

Indexed keywords

EID: 38049175059     PISSN: None     EISSN: 15269914     Source Type: Journal    
DOI: 10.1120/jacmp.v8i4.2685     Document Type: Article

References (32)

1. Bey P, Carrie C, Beckendorf V, et al. Dose escalation with 3D-CRT in prostate cancer: French study of dose escalation with conformal 3D radiotherapy in prostate cancer-preliminary results. Int J Radiat Oncol Biol Phys. 2000;48(2):513-517.
2. Zelefsky MJ, Leibel SA, Gaudin PB, et al. Dose escalation with three-dimensional conformal radiation therapy affects the outcome in prostate cancer. Int J Radiat Oncol Biol Phys. 1998;41(3):491-500.
3. Hanks GE, Hanlon AL, Schultheiss TE, et al. Dose escalation with 3D conformal treatment: five year outcomes, treatment optimization, and future directions. Int J Radiat Oncol Biol Phys. 1998;41(3):501-510.
4. Pollack A, Zagars GK, Starkschall G, et al. Prostate cancer radiation dose response: results of the M.D. Anderson phase III randomized trial. Int J Radiat Oncol Biol Phys. 2002;53(5):1097-1105.
5. Lyons JA, Kupelian PA, Mohan DS, Reddy CA, Klein EA. Importance of high radiation doses (72 Gy or greater) in the treatment of stage T1-T3 adenocarcinoma of the prostate. Urology. 2000;55(1):85-90.
6. Hanks GE, Hanlon AL, Epstein B, Horwitz EM. Dose response in prostate cancer with 8-12 years' follow-up. Int J Radiat Oncol Biol Phys. 2002;54(2):427-435.
7. Pollack A, Smith LG, von Eschenbach AC. External beam radiotherapy dose response characteristics of 1127 men with prostate cancer treated in the PSA era. Int J Radiat Oncol Biol Phys. 2000;48(2):507-512.
8. Followill D, Geis P, Boyer A. Estimates of whole-body dose equivalent produced by beam intensity modulated conformal therapy. Int J Radiat Oncol Biol Phys. 1997;38(3):667-672.
9. Webb S. Conformal intensity-modulated radiotherapy (IMRT) delivered by robotic LINAC - conformality versus efficiency of dose delivery. Phys Med Biol. 2000;45(7):1715-1730.
10. Brenner DJ, Curtis RE, Hall EJ, Ron E. Second malignancies in prostate carcinoma patients after radiotherapy compared with surgery. Cancer. 2000;88(2):398-406.
11. Boice JD Jr, Day NE, Andersen A, et al. Second cancers following radiation treatment for cervical cancer. An international collaboration among cancer registries. J Natl Cancer Inst. 1985;74(5):955-975.
12. Movsas B, Hanlon AL, Pinover W, Hanks GE. Is there an increased risk of second primaries following prostate irradiation? Int J Radiat Oncol Biol Phys. 1998;41(2):251-255.
13. Dorr W, Herrmann T. Cancer induction by radiotherapy: dose dependence and spatial relationship to irradiated volume. J Radiol Prot. 2002;22(3A):A117-A12l.
14. Upton AC. The dose-response relation in radiation-induced cancer. Cancer Res. 1961;21:717-729.
15. Curtis RE, Boice JD Jr, Stovall M, et al. Relationship of leukemia risk to radiation dose following cancer of the uterine corpus. J Natl Cancer Inst. 1994;86(17):1315-1324.
16. Blettner M, Boice JD Jr. Radiation dose and leukaemia risk: general relative risk techniques for dose-response models in a matched case-control study. Stat Med. 1991;10(10):1511-1526.
17. Boice JD Jr, Blettner M, Kleinerman RA, et al. Radiation dose and leukemia risk in patients treated for cancer of the cervix. J Natt Cancer Inst. 1987;79(6):1295-1311.
18. Day N, Boice JD Jr, eds. Second cancers in relation to radiation treatment for cervical cancer: results of a cancer registry collaboration. IARC Scientific Publications No. 52. Lyon (France): IARC Press; 1983.
19. Price RA, Chibani O, Ma CM. Shielding evaluation for IMRT implementation in an existing accelerator vault. J Appl Clin Med Phys. 2003;4(3):231-238.
20. Intensity Modulated Radiation Therapy Collaborative Working Group. Intensity-modulated radiotherapy: current status and issues of interest. Int J Radiat Oncol Biol Phys. 2001;51(4):880-914.
21. International Commission on Radiological Protection (ICRP). 1990 Recommendations of the International Commission on Radiological Protection. ICRP publication 60. Oxford (U.K.): Pergamon Press; 1991.
22. National Council on Radiation Protection and Measurements (NCRP). Limitation of exposure to ionizing radiation: recommendations of the National Council on Radiation Protection and Measurements. NCRP Report No. 116. Bethesda (MD): NCRP; 1993.
23. Rogers DW, Faddegon BA, Ding X, Ma CM, We J, Mackie TR. BEAM: a Monte Carlo code to simulate radiotherapy treatment units. Med Phys. 1995;22(5):503-524.
24. Ma CM, Li J, Pawlicki T, et al. MCSIM - a Monte Carlo dose calculation tool for radiation therapy In: Yi BY, Ahn SD, Choi EK, Ha SW, editors. Proceedings of the XIVth International Conference on the Use of Computers in Radiation Therapy (ICCR). Seoul (Korea): Jeong Publishing; 2004: 515-519.
25. Nelson WR, Hirayama H, Rogers DWO. The EGS4 code system. Stanford Linear Accelerator Center (SLAC) Report No. 265. Stanford (CA): Stanford Linear Accelerator Center; 1985.
26. Bielajew AF, Rogers DWO. PRESTA: the parameter reduced electron-step transport algorithm for electron Monte Carlo transport. Nucl Instrum Methods. 1987;B18:165-181.
27. Kapur A, Ma CM, Mok E, Findley D. Characterization of small field electron beams for radiotherapy using Monte Carlo simulations. In: Proceedings of the XIIth conference on the use of computers in radiotherapy. Madison (WI): Medical Physics Publishing; 1997: 157-158.
28. Ma CM, Faddegon BA, Rogers DW, Mackie TR. Accurate characterization of Monte Carlo calculated electron beams for radiotherapy. Med Phys. 1997;24(3):401-416.
29. Deng J, Jiang SB, Kapur A, Li J, Pawlicki T, Ma CM. Photon beam characterization and modelling for Monte Carlo treatment planning. Phys Med Biol. 2000;45(2):411-427.
30. Yang J, Li JS, Qin L, Yiong W, Ma CM. Modelling ofelectron contamination in clinical photon beams for Monte Carlo dose calculation. Phys Med Biol. 2004;49(12):2657-2673.
31. Hall E, Wuu CS. The impact of IMRT on the incidence ofradiation-induced second cancers. Int J Radiat Oncol Biol Phys. 2003;56(1):83-88.
32. Kry SF, Salehpour M, Followill S, et al. Out-of-field photon and neutron dose equivalents firom step-and-shoot intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys. 2005;62(4):1204-1216.