메뉴 건너뛰기




Volumn 4, Issue 1 SUPPL. 1, 2008, Pages

A perspective on risks that impede development of drugs to modify the course of Alzheimer's disease: Can they be reduced?

Author keywords

Clinical trials; Drug development; Policy; Regulation

Indexed keywords

CHOLINESTERASE INHIBITOR; DONEPEZIL; GALANTAMINE; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEW DRUG; NOOTROPIC AGENT; RIVASTIGMINE;

EID: 38049130003     PISSN: 15525260     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jalz.2007.11.011     Document Type: Article
Times cited : (7)

References (12)
  • 1
    • 38049121102 scopus 로고    scopus 로고
    • Center for Drug Evaluation and Research, US Food and Drug Administration, Rockville, MD Available at: www.fda.gov/cder/rdmt/numofndareccy.htm. Accessed: November 2, 2007
    • Center for Drug Evaluation and Research. Number of NDAs received by calendar year (2007), US Food and Drug Administration, Rockville, MD. http://www.fda.gov/cder/rdmt/numofndareccy.htm Available at: www.fda.gov/cder/rdmt/numofndareccy.htm. Accessed: November 2, 2007
    • (2007) Number of NDAs received by calendar year
  • 2
    • 38049144375 scopus 로고    scopus 로고
    • Center for Drug Evaluation and Research, US Food and Drug Administration, Rockville, MD Available at: www.fda.gov/cder/rdmt/pstable.htm. Accessed: November 2, 2007
    • Center for Drug Evaluation and Research. NDAs approved by calendar years 1990-2004 (2005), US Food and Drug Administration, Rockville, MD. http://www.fda.gov/cder/rdmt/pstable.htm Available at: www.fda.gov/cder/rdmt/pstable.htm. Accessed: November 2, 2007
    • (2005) NDAs approved by calendar years 1990-2004
  • 3
    • 38049113056 scopus 로고    scopus 로고
    • Center for Drug Evaluation and Research, US Food and Drug Administration, Rockville, MD
    • Center for Drug Evaluation and Research. 2007 CDER update (2007), US Food and Drug Administration, Rockville, MD
    • (2007) 2007 CDER update
  • 4
  • 5
    • 34547747293 scopus 로고    scopus 로고
    • Harvard Business School Press, Boston
    • Pisano G.P. Science business (2006), Harvard Business School Press, Boston
    • (2006) Science business
    • Pisano, G.P.1
  • 6
    • 33744900086 scopus 로고    scopus 로고
    • Perspective: optimal design of clinical trials for drugs designed to show the course of Alzheimer's disease
    • Mohs R.C., Kawas C., and Carrillo M.C. Perspective: optimal design of clinical trials for drugs designed to show the course of Alzheimer's disease. Alzheimer's & Dementia 2 (2006) 131-139
    • (2006) Alzheimer's & Dementia , vol.2 , pp. 131-139
    • Mohs, R.C.1    Kawas, C.2    Carrillo, M.C.3
  • 7
    • 5644239087 scopus 로고    scopus 로고
    • Alzheimer disease: mechanistic understanding predicts novel therapies
    • Selkoe D.J. Alzheimer disease: mechanistic understanding predicts novel therapies. Ann Intern Med 140 (2004) 627-638
    • (2004) Ann Intern Med , vol.140 , pp. 627-638
    • Selkoe, D.J.1
  • 8
    • 4644352071 scopus 로고    scopus 로고
    • Clinical trial registration: a statement from the international committee of medical journal editors
    • De Angelis C., Drazen J.M., Frizelle F.A., Haug C., Hoey J., Horton R., et al. Clinical trial registration: a statement from the international committee of medical journal editors. Ann Intern Med 141 (2004) 477-478
    • (2004) Ann Intern Med , vol.141 , pp. 477-478
    • De Angelis, C.1    Drazen, J.M.2    Frizelle, F.A.3    Haug, C.4    Hoey, J.5    Horton, R.6
  • 10
    • 0030268577 scopus 로고    scopus 로고
    • Surrogate end points in clinical trials: are we being misled?
    • Flemming T.R., and DeMets D.L. Surrogate end points in clinical trials: are we being misled?. Ann Intern Med 125 (1996) 605-613
    • (1996) Ann Intern Med , vol.125 , pp. 605-613
    • Flemming, T.R.1    DeMets, D.L.2
  • 11
    • 33744941316 scopus 로고    scopus 로고
    • Perspectives on assessing benefits and risks in clinical trials for Alzheimer's disease
    • McConnell S., Karlawish J., Vellas B., and DeKosky S. Perspectives on assessing benefits and risks in clinical trials for Alzheimer's disease. Alzheimer's & Dementia 3 (2006) 160-163
    • (2006) Alzheimer's & Dementia , vol.3 , pp. 160-163
    • McConnell, S.1    Karlawish, J.2    Vellas, B.3    DeKosky, S.4
  • 12
    • 33746205373 scopus 로고    scopus 로고
    • Clinical trials design and treatment tailoring: general principles applied to breast cancer research
    • Therasse P., Carbonnelle S., and Bogaerts J. Clinical trials design and treatment tailoring: general principles applied to breast cancer research. Crit Rev Oncol/Hematol 59 (2006) 98-105
    • (2006) Crit Rev Oncol/Hematol , vol.59 , pp. 98-105
    • Therasse, P.1    Carbonnelle, S.2    Bogaerts, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.