MTHFR C677T polymorphisms among the Ahirs and Jats of Haryana (India)

American Journal of Human Biology

Volumn 20, Issue 1, 2008, Pages 116-117

  Saraswathy, K N ^a   Mukhopadhyay, Rupak ^a   Sinha, Ekata ^a   Aggarwal, Shweta ^b   Sachdeva, M P ^a   Kalla, A K ^a  

^a UNIVERSITY OF DELHI   (India)

^b DRDO   (India)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ALANINE; DNA; HOMOCYSTEINE; METHIONINE; METHYLENETETRAHYDROFOLIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; VALINE;

ALLELE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DNA EXTRACTION; ETHNIC DIFFERENCE; FEMALE; GENE FREQUENCY; GENE MUTATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SELECTION; HEART INFARCTION; HOMOZYGOSITY; HUMAN; HUMAN CELL; HYPERTENSION; INDIA; MALE; METHYLATION; NEURAL TUBE DEFECT; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION; POPULATION GENETICS; PRIORITY JOURNAL; RECURRENT ABORTION; STROKE; THROMBOSIS;

GENE FREQUENCY; HUMANS; INDIA; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); POLYMORPHISM, SINGLE NUCLEOTIDE; POPULATION GROUPS; SOCIAL CLASS;

EID: 38049125769     PISSN: 10420533     EISSN: 15206300     Source Type: Journal    
DOI: 10.1002/ajhb.20682     Document Type: Article

References (14)

1. Aggarwal S. 2006. Demo genetic diversity among Jats and Ahirs of Haryana, Unpublished Ph.D. thesis. Department of Anthropology, University of Delhi, India.
2. Arruda V, von Zuben P, Chiaparinil C, Annichino-Bizzacchi JM, Costa FF. 1997. The mutation Ala677- Val in the methylenetetrahydrofolate reductase gene: a risk factor for arterial disease and venous thrombosis. Thromb Haemost 77:818-821.
3. Botto LD, Yang Q. 2000. 5, 10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. Am J Epidemiol 151:862-877.
4. Jiang S, Hsu Y, Xu X, Xing H, Chen C, Niu T, Zhang Y, Peng S, Xu X. 2004. The C677T polymorphism of the methylenetetrahydrofolate reductase gene is associated with the level of decrease on diastolic blood pressure in essential hypertension patients treated by angiotensin-converting enzyme inhibitor. Thromb Res 113:361-369.
5. Kang SS, Zhou J, Wong PWK, Kowalisyn J, Strokosch G. 1988. Intermediate homocystenemia: a thermolabile variant of methylenetetrahydrofolate reductase. Am J Hum Genet 43:414-421.
6. Kark J, Sinnreich R, Rosenberg I, Jacques P, Selhub J. 2002. Plasma homocysteine and parental myocardial infarction in young adults in Jerusalem. Circulation 105:2725-2729.
7. Kelly P, Rosand J, Kistler J, Shih V, Silveira S, Plomaritoglou, Furie K. 2002. Homocysteine, MTHFR 677C→T polymorphism, and risk of ischemic stroke. Neurology 59:529-536.
8. Martinelli I, Battaglioli T, Pedotti P, Cattaneo M, Mannuci PM. 2003. Hyperhomocysteinemia in cerebral vein thrombosis. Blood 102:1363-1366.
9. Mtiraoui N, Zammiti W, Ghazouani L, Braham NJ, Saidi S, Finan RR, Almawi WY, Mahjoub T. 2006. Methylenetetrahydrofolate reductase C677T and A1298C polymorphism and changes in homocysteine concentrations in women with idiopathic recurrent pregnancy losses. Reproduction 131:395-401.
10. Mukhopadhyay R. 2006. Study on some molecular risk factor related to habitual recurrent abortions in a north Indian population, Unpublished Ph.D. thesis. Department of Anthropology, University of Delhi, India.
11. Pepe G, Vanegas OC, Giusti B, Brunelli T, Marucci R, Attanasio M, Rickards O, De Stefano GF, Prisco D, Gensisni GF, Abbate R. 1998. Heterogeneity in world distribution of the thermolabile C677T mutation in 5, 10-methylenetetrahydrofolate reductase. Am J Hum Genet 63:917-920.
12. Radha Rama Devi A, Govindaiah V, Ramakrishna G, Naushad SM. 2004. Prevalence of methylenetetrahydrofolate reductase polymorphism in south Indian population. Curr Sci 86:440-433.
13. Sadewa AH, Sunarti, Retno S, Hayashi C, Lee MJ, Ayaki H, Sofro ASM, Matsuo M, Nishio H. 2002. The C677T Mutation in the methylenetetrahydrofolate reductase gene among the Indonesian Javanese population. Kobe J Med Sci 48:137-144.
14. Van der putt NMJ, Eskes TKAB, Blom HJ. 1997. Is the common 677CT mutation in the methylenetetrahydrofolate reductase gene a risk factor for neural tube defects? A meta-analysis. Q J Med 90:111-115.