Stilbene derivatives inhibit the activity of the inner mitochondrial membrane chloride channels

Cellular and Molecular Biology Letters

Volumn 12, Issue 4, 2007, Pages 493-508

  Koszela Piotrowska, Izabela ^a   Choma, Katarzyna ^a,b   Bednarczyk, Piotr ^a,b   Dołowy, Krzysztof ^b   Szewczyk, Adam ^a   Kunz, Wolfram S ^c   Malekova, Lubica ^d   Kominkova, Viera ^d   Ondrias, Karol ^d  

^a NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

^b WARSAW UNIVERSITY OF LIFE SCIENCES   (Poland)

^c UNIVERSITY OF BONN   (Germany)

^d INSTITUTE OF MOLECULAR PHYSIOLOGY AND GENETICS   (Slovakia)

Author keywords

Black lipid membrane; Chloride channel; Mitochondria; Stilbene derivatives

Indexed keywords

4 ACETAMIDO 4' ISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; CHLORIDE CHANNEL; CHLORIDE ION; POTASSIUM CHLORIDE; STILBENE DERIVATIVE;

ANIMAL CELL; ARTICLE; BRAIN MITOCHONDRION; CELL VOLUME; HEART MITOCHONDRION; LIPID BILAYER; MEMBRANE CONDUCTANCE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; RAT; SKELETAL MUSCLE;

RATTUS;

EID: 38049103517     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-007-0019-9     Document Type: Article

References (37)

1. Szewczyk, A., Skalska, J., Glab, M., Kulawiak, B., Malinska, D., Koszela-Piotrowska, I. and Kunz, W.S. Mitochondrial potassium channels: From pharmacology to function. Biochim. Biophys. Acta 1757 (2006) 715-720.
2. Wang, X., Takahashi, N., Uramoto, H. and Okada, Y. Chloride channel inhibition prevents ROS-dependent apoptosis induced by ischemia-reperfusion in mouse cardiomyocytes. Cell. Physiol. Biochem. 16 (2005) 147-154.
3. Beavis, A.D. and Garlid, K.D. The mitochondrial inner membrane anion channel. Regulation by divalent cations and protons. J. Biol. Chem. 262 (1987) 15085-15093.
4. Beavis, A.D. Properties of the inner membrane anion channel in intact mitochondria. J. Bioenerg. Biomembr. 24 (1992) 77-90.
5. Schönfeld, P., Sayeed, I., Bohnensack, R. and Siemen, D. Fatty acids induce chloride permeation in rat liver mitochondria by activation of the inner membrane anion channel (IMAC). J. Bioenerg. Biomembr. 36 (2004) 241-248.
6. Sorgato, M.C., Keller, B.U. and Stuhmer, W. Patch-clamping of the inner mitochondrial membrane reveals a voltage-dependent ion channel. Nature 330 (1987) 498-500.
7. Sorgato, M.C., Moran, O., De Pinto, V., Keller, B.U. and Stuehmer, W. Further investigation on the high-conductance ion channel of the inner membrane of mitochondria. J. Bioenerg. Biomembr. 21 (1989) 485-496.
8. Moran, O., Sandri, G., Panfili, E., Stuhmer, W. and Sorgato, M.C. Electrophysiological characterization of contact sites in brain mitochondria. J. Biol. Chem. 265 (1990) 908-913.
9. Klitsch, T. and Siemen, D. Inner mitochondrial membrane anion channel is present in brown adipocytes but is not identical with the uncoupling protein. J. Membr. Biol. 122 (1991) 69-75.
10. Borecky, J., Jezek, P. and Siemen, D. 108-pS channel in brown fat mitochondria might be identical to the inner membrane anion channel. J. Biol. Chem. 272 (1997) 19282-19289.
11. Hayman, K.A., Spurway, T.D. and Ashley, R.H. Single anion channels reconstituted from cardiac mitoplasts. J. Membrane Biol. 136 (1993) 181-190.
12. Fernandez-Salas, E., Sagar, M., Cheng, C., Yuspa, S.H. and Weinberg, W.C. p53 and tumor necrosis factor alpha regulate the expression of a mitochondrial chloride channel protein. J. Biol. Chem. 274 (1999) 36488-36497.
13. Landry, D., Sullivan, S., Nicolaides, M., Redhead, C., Edelman, A., Field, M., al-Awqati, Q. and Edwards, J. Molecular cloning and characterization of p64, a chloride channel protein from kidney microsomes. J. Biol. Chem. 268 (1993) 14948-14955.
14. Tonini, R., Ferroni, A., Valenzuela, S.M., Warton, K., Campbell, T.J., Breit, S.N. and Mazzanti, M. Functional characterization of the NCC27 nuclear protein in stable transfected CHO-K1 cells. FASEB J. 14 (2000) 1171-1178.
15. 2+ and ATP. Biochem. J. 390 (2005) 333-343.
16. Qian, Z., Okuhara, D., Abe, M.K. and Rosner, M.R. Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel. J. Biol. Chem. 274 (1999) 1621-1627.
17. Berryman, M., Bruno, J., Price, J. and Edwards, J.C. CLIC-5A functions as a chloride channel in vitro and associates with the cortical actin cytoskeleton in vitro and in vivo. J. Biol. Chem. 279 (2004) 34794-34801.
18. Friedli, M., Guipponi, M., Bertrand, S., Bertrand, D., Neerman-Arbez, M., Scott, H.S., Antonarakis, S.E. and Reymond, A. Identification of a novel member of the CLIC family, CLIC6, mapping to 21q22.12. Gene 320 (2003) 31-40.
19. Mizukawa, Y., Nishizawa, T., Nagao, T., Kitamura, K. and Urushidani, T. Cellular distribution of parchorin, a chloride intracellular channel-related protein, in various tissues. Am. J. Physiol. Cell Physiol. 282 (2002) C786-795.
20. Suh, K.S., Mutoh, M., Gerdes, M. and Yuspa, S.H. CLIC4, an intracellular chloride channel protein, is a novel molecular target for cancer therapy. J. Investig. Dermatol. Symp. Proc. 10 (2005) 105-109.
21. Fernandez-Salas, E., Suh, K.S., Speransky, V.V., Bowers, W.L., Levy, J.M., Adams, T., Pathak, K.R., Edwards, L.E., Hayes, D.D., Cheng, C., Steven, A.C., Weinberg, W.C. and Yuspa, S.H. mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53. Mol. Cell Biol. 22 (2002) 3610-3620.
22. Suh, K.S., Mutoh, M., Nagashima, K., Fernandez-Salas, E., Edwards, L.E., Hayes, D.D., Crutchley, J.M., Marin, K.G., Dumont, R.A., Levy, J.M., Cheng, C., Garfield, S. and Yuspa, S.H. The organellular chloride channel protein CLIC4/mtCLIC translocates to the nucleus in response to cellular stress and accelerates apoptosis. J. Biol. Chem. 279 (2004) 4632-4641.
23. Singh, H. and Ashley, R.H. CLIC4 (p64H1) and its putative transmembrane domain form poorly selective, redox-regulated ion channels. Mol. Membr. Biol. 24 (2007) 41-52.
24. Wiśniewski, E., Kunz, W.S. and Gellerich, F.N. Phosphate affects the distribution of flux control among the enzymes of oxidative phosphorylation in rat skeletal muscle mitochondria. J. Biol. Chem. 268 (1993) 9343-9346.
25. Dȩbska, G., Kicińska, A., Skalska, J., Szewczyk, A., May, R., Elger, C.E. and Kunz, W.S. Opening of potassium channels modulates mitochondrial function in rat skeletal muscle. Biochim. Biophys. Acta 1556 (2002) 97-105.
26. Kudin, A, Bimpong-Buta, N.Y., Vielhaber, S., Elger, C.E. and Kunz, W.S. Characterization of superoxide-producing sites in isolated brain mitochondria. J. Biol. Chem. 279 (2004) 4127-4135.
27. Cino, M. and Del Maestro, R.F. Generation of hydrogen peroxide by brain mitochondria: the effect of reoxygenation following postdecapitative ischemia. Arch. Biochem. Biophys. 269 (1989) 623-638.
28. 2+ overload in rat cardiac mitochondria. J. Physiol. 519 (1999) 347-360.
29. Malekova, L., Kominkova, A., Ferko, M., Stefanik, P., Krizanova, O., Ziegelhöffer, A., Szewczyk, A. and Ondrias, K. Bongkrekic acid and atractyloside inhibits chloride channels from mitochondrial membranes of rat heart. Biochim. Biophys. Acta 1767 (2007) 31-44.
30. Bednarczyk, P., Kicińska, A., Kominkova, V., Ondrias, K., Do?owy K. and Szewczyk, A. Quinine inhibits mitochondrial ATP-regulated potassium channel from bovine heart. J. Membr. Biol. 199 (2004) 63-72.
31. 2+ regulates mitochondrial ATP-dependent potassium channel from heart. FEBS Lett. 579 (2005) 1625-1632.
32. Kulawiak, B. and Bednarczyk, P. Reconstitution of brain mitochondria inner membrane into planar lipid bilayer Acta Neurobiol. Exp. (Wars). 65 (2005) 271-276.
33. Hordejuk, R., Szewczyk, A. and Dołowy K. The heterogeneity of ion channels in chromaffin granule membranes. Cell. Mol. Biol. Lett. 11 (2006) 312-325.
34. Cabantchik, Z.I. and Greger, R. Chemical probes for anion transporters of mammalian cell membranes. Am. J. Physiol. 262 (1992) 803-827.
35. Jentsch, T.J., Stein, V., Weinreich, F. and Zdebik, A.A. Molecular structure and physiological function of chloride channels. Physiol. Rev. 82 (2002) 503-568.
36. Beavis, A.D. and Davatol-Hag, H. The mitochondrial inner membrane anion channel is inhibited by DIDS. J. Bioenerg. Biomembr. 28 (1996) 207-214.
37. Huang, S.G. and Klingenberg, M. Chloride channel properties of the uncoupling protein from brown adipose tissue mitochondria: a patch-clamp study. Biochemistry 35 (1996) 16806-16814.