Ability of suramin to antagonize the cardiotoxic and some enzymatic activities of Bothrops jararacussu venom

Toxicon

Volumn 51, Issue 1, 2008, Pages 28-36

  Sifuentes, Daniel N ^b   El Kik, Camila Z ^a   Ricardo, Hilmar D ^a   Tomaz, Marcelo A ^a   Strauch, Marcelo A ^a   Calil Elias, Sabrina ^c   Arruda, Emerson Z ^d   Schwartz, Elisabeth F ^b   Melo, Paulo A ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b UNIVERSITY OF BRASILIA   (Brazil)

^c Administracao Farmaceutica   (Brazil)

^d FEDERAL UNIVERSITY OF SÃO JOÃO DEL REI   (Brazil)

Author keywords

Bothrops jararacussu venom; Cardiotoxicity; Proteolytic and phospholipase A2 activity; Suramin

Indexed keywords

ANTIBOTHROPIC POLYVALENT ANTIVENOM; BATROXOBIN; CREATINE KINASE; PHOSPHOLIPASE A2; RINGER SOLUTION; SNAKE VENOM ANTISERUM; SURAMIN; UNCLASSIFIED DRUG;

ADJUVANT THERAPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOTOXICITY; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTINUOUS INFUSION; CONTROLLED STUDY; ENZYME ACTIVITY; HEART MUSCLE TENSION; ISOLATED HEART; MALE; NONHUMAN; PERFUSION; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; SNAKE;

ANIMALS; BOTHROPS; CARDIOTOXINS; CROTALID VENOMS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART; MALE; PEPTIDE HYDROLASES; PHOSPHOLIPASES; PROTEASE INHIBITORS; RATS; RATS, WISTAR; SURAMIN; TIME FACTORS;

BOTHROPS JARARACUSSU; RATTUS;

EID: 38049103306     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2007.07.002     Document Type: Article

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