High absolute risks and predictors of venous and arterial thromboembolic events in patients with nephrotic syndrome: Results from a large retrospective cohort study

Circulation

Volumn 117, Issue 2, 2008, Pages 224-230

  Mahmoodi, Bakhtawar K ^a   Ten Kate, Min Ki ^a   Waanders, Femke ^a   Veeger, Nic J G M ^a   Brouwer, Jan Leendert P ^a   Vogt, Liffert ^a   Navis, Gerjan ^a   Van Der Meer, Jan ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Cardiovascular diseases; Nephrotic syndrome; Proteinuria; Risk factors; Thrombosis

Indexed keywords

ALBUMIN;

ADULT; AGE; AGED; ALBUMIN BLOOD LEVEL; ARTERY EMBOLISM; ARTERY THROMBOSIS; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; COHORT ANALYSIS; DEEP VEIN THROMBOSIS; DIABETES MELLITUS; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; HYPERTENSION; KAPLAN MEIER METHOD; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; NEPHROTIC SYNDROME; PREDICTION; PRIORITY JOURNAL; PROTEINURIA; RETROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; SEX DIFFERENCE; SMOKING; VENOUS THROMBOEMBOLISM;

ADULT; ARTERIES; COHORT STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; NEPHROTIC SYNDROME; ODDS RATIO; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RETROSPECTIVE STUDIES; RISK FACTORS; THROMBOEMBOLISM; VENOUS THROMBOEMBOLISM;

EID: 38049103204     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.107.716951     Document Type: Article

References (34)

1. Addis T. Glumerular nephritis. In: Glomerular Nephritis Diagnosis and Treatment. New York, NY: McMillan; 1948:179-221.
2. Fishberg AM. Chronic nephrosis. In: HYPERTENSION AND NEPHRITIS. 5th ed. London, UK: Baillière, Tindall & Cox; 1954: 445-500.
3. Lilova MI, Velkovski IG, Topalov IB. Thromboembolic complications in children with nephrotic syndrome in Bulgaria (1974-1996). Pediatr Nephrol. 2000;15:74-78.
4. Velasquez Forero F, Garcia Prugue N, Ruiz Morales N. Idiopathic nephrotic syndrome of the adult with asymptomatic thrombosis of the renal vein. Am J Nephrol. 1988;8:457-462.
5. Llach F. Hypercoagulability, renal vein thrombosis, and other thrombotic complications of nephrotic syndrome. Kidney Int. 1985;28:429-439.
6. Sagripanti A, Barsotti G. Hypercoagulability, intraglomerular coagulation, and thromboembolism in nephrotic syndrome. Nephron. 1995;70:271-281.
7. Wass VJ, Jarrett RJ, Chilvers C, Cameron JS. Does the nephrotic syndrome increase the risk of cardiovascular disease? Lancet. 1979;2:664-667.
8. Ordonez JD, Hiatt RA, Killebrew EJ, Fireman BH. The increased risk of coronary heart disease associated with nephrotic syndrome. Kidney Int. 1993;44:638-642.
9. Llach F, Papper S, Massry SG. The clinical spectrum of renal vein thrombosis: acute and chronic. Am J Med. 1980;69:819-827.
10. Singhal R, Brimble KS. Thromboembolic complications in the nephrotic syndrome: pathophysiology and clinical management. Thromb Res. 2006;118:397-407.
11. Bellomo R, Atkins RC. Membranous nephropathy and thromboembolism: is prophylactic anticoagulation warranted? Nephron. 1993;63:249-254.
12. Collet JP, Mishal Z, Lesty C, Mirshahi M, Peyne J, Baumelou A, Bensman A, Soria J, Soria C. Abnormal fibrin clot architecture in nephrotic patients is related to hypofibrinolysis: influence of plasma biochemical modifications: a possible mechanism for the high thrombotic tendency? Thromb Haemost. 1999;82:1482-1489.
13. Bellomo R, Wood C, Wagner I, Agar J, Dowling J, Thomson N, Atkins R. Idiopathic membranous nephropathy in an Australian population: the incidence of thromboembolism and its impact on the natural history. Nephron. 1993;63:240-241.
14. Joven J, Villabona C, Vilella E, Masana L, Alberti R, Valles M. Abnormalities of lipoprotein metabolism in patients with the nephrotic syndrome. N Engl J Med. 1990;323:579-584.
15. Ozsoylu S, Strauss HS, Diamond LK. Effects of corticosteroids on coagulation of the blood. Nature. 1962;195:1214-1215.
16. Robert A, Olmer M, Sampol J, Gugliotta JE, Casanova P. Clinical correlation between hypercoagulability and thromboembolic phenomena. Kidney int. 1987;31:830-835.
17. Ginsberg JM, Chang BS, Matarese RA, Garella S. Use of single voided urine samples to estimate quantitative proteinuria. N Engl J Med. 1983;309:1543-1546.
18. Orth SR, Ritz E. The nephrotic syndrome. N Engl J Med. 1998;338:1202-1211.
19. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 1997;20:1183-1197.
20. DECODE Study Group. Is fasting glucose sufficient to define diabetes? Epidemiological data from 20 European studies. Diabetologia. 1999;42:647-654.
21. Stevens LA, Coresh J, Greene T, Levey AS. Assessing kidney function: measured and estimated glomerular filtration rate. N Engl J Med. 2006;354:2473-2483.
22. Special report from the National Institute of Neurological Disorders and Stroke: classification of cerebrovascular diseases III. Stroke. 1990;21:637-676.
23. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457-481.
24. Cox DR. Regression models and lifetables. J R Stat Soc [B]. 1972;34:187-220.
25. Anderson FA Jr, Wheeler HB, Goldberg RJ, Hosmer DW, Patwardhan NA, Jovanovic B, Forcier A, Dalen JE. A population-based perspective of the hospital incidences and case-fatality rates of deep vein thrombosis and pulmonary embolism: the Worcester DVT study. Arch Intern Med. 1991;151:933-938.
26. Thom TJ, Kannel WB, Silbershatz H, D'Agostino RB. Incidence, prevalence, and mortality of cardiovascular diseases in the United States. In: Alexander RW, Schlant RC, Fuster V, eds. Hurst's The Heart. 9th ed. New York, NY: McGraw-Hill; 1998:3-17.
27. Andrassy K, Ritz E, Bonner J. Hypercoagulability in the nephrotic syndrome. Klin Wochenschr. 1980;58:1029-1036.
28. Kanfer A, Kleinknecht D, Broyer M, Josso F. Coagulation studies in 45 cases of nephrotic syndrome without uremia. Thromb Diath Haemorrh. 1970;24:562-571.
29. Wass V, Cameron JS. Cardiovascular disease and the nephrotic syndrome: the other side of the coin. Nephron. 1981;27:58-61.
30. De Zeeuw D, Remuzzi G, Parving HH, Keane WF, Zhang Z, Shahinfar S, Snapinn S, Cooper ME, Mitch WE, Brenner BM. Albuminuria, a therapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathy. Circulation. 2004;110:921-927.
31. Hillege HL, Janssen WMT, Bak AAA, Diercks GFH, Grobbee DE, Crijns HJGM, van Gilst WH, de Zeeuw D, de Jong PE. Microalbuminuria is common, also in a nondiabetic, nonhypertensive population, and an independent indicator of cardiovascular risk factors and cardiovascular morbidity. J Intern Med. 2001;249:519-526.
32. Schena FP. Primary glomerulonephritides with nephrotic syndrome: limitations of therapy in adult patients. J Nephrol. 1999;12(suppl 2):S125-S130.
33. Bova C, Marchiori A, Noto A, Rossi V, Daniele F, Santoro C, Ricchio R, De Lorenzo R, Umbaca R, Prandoni P. Incidence of arterial cardiovascular events in patients with idiopathic venous thromboembolism. Thromb Haemost. 2006;96:132-136.
34. Prandoni P, Bilora F, Marchiori A, Bernardi E, Petrobelli F, Lensing AWA, Prins MH, Girolami A. An association between atherosclerosis and venous thrombosis. N Engl J Med. 2003;348:1435-1441.