Development of an effective whole-spore vaccine to protect against microsporidial gill disease in rainbow trout (Oncorhynchus mykiss) by using a low-virulence strain of Loma salmonae

Clinical and Vaccine Immunology

Volumn 14, Issue 12, 2007, Pages 1652-1654

  Speare, D J ^a   Markham, R J F ^a   Guselle, N J ^a  

^a UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FREUND ADJUVANT; VACCINE;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; EXPERIMENTAL INFECTION; GILL; IMMUNE RESPONSE; INFECTION; LOMA; LOMA SALMONAE; MICROSPORIDIOSIS; NONHUMAN; PRIORITY JOURNAL; RAINBOW TROUT; VACCINATION; VIRULENCE;

ADMINISTRATION, ORAL; ANIMALS; FISH DISEASES; FISHERIES; GILLS; LOMA; MICROSPORIDIOSIS; ONCORHYNCHUS MYKISS; SPECIFIC PATHOGEN-FREE ORGANISMS; SPORES, PROTOZOAN; TIME FACTORS; VACCINES;

EID: 38049081563     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00365-07     Document Type: Article

References (16)

1. Carrington, A. C., and C. J. Secombes. 2006. A review of CpGs and their relevance to aquaculture. Vet. Immunol. Immunopathol. 112:87-101.
2. Keeling, P. J., and N. M. Fast. 2002. Microsporidia: biology and evolution of highly reduced intracellular parasites. Annu. Rev. Microbiol. 56:93-116.
3. Kent, M. L., and D. J. Speare. 2005. Review of the sequential development of Loma salmonae (Microsporidia) based on experimental infections with rainbow trout (Oncorhynchus mykiss) and chinook salmon (O. tshawytscha). Folia Parasitol. 52:1-6.
4. Kent, M. L., G. S. Traxler, D. Kieser, J. Richard, S. C. Dawe, R. W. Shaw, G. Prosperi-Porta, J. Ketcheson, and T. P. T. Evelyn. 1998. Survey of salmonid pathogens in ocean-caught fishes in British Columbia, Canada. J. Aquat. Anim. Health 10:211-219.
5. Leiro, J., M. Ortega, J. Estevez, M. T. Santamarina, M. L. Sanmartin, and F. M. Ubeira. 1996. The humoral immune response of turbot, Scophthalmus maximus L., to spore-surface antigens of microsporidian parasites. Vet. Immunol. Immunopathol. 55:235-242.
6. Ramsay, J. M., D. J. Speare, J. G. Sanchez, and J. Daley. 2001. The transmission potential of Loma salmonae (Microspora) in the rainbow trout, Oncorhynchus mykiss (Walbaum), is dependent upon the method and timing of exposure. J. Fish Dis. 24:453-460.
7. Rodriguez-Tovar, L. E., R. J. F. Markham, D. J. Speare, and J. Sheppard. 2006. Cellular immunity in salmonids infected with the microsporidial parasite Loma salmonae or exposed to non-viable spores. Vet. Immunol. Immunopathol. 114:72-83.
8. Rodriguez-Tovar, L. E., J. A. Becker, R. J. F. Markham, and D. J. Speare. 2006. Induction time for resistance to microsporidial gill disease caused by Loma salmonae following vaccination of rainbow trout (Oncorhynchus mykiss) with a spore-based vaccine. Fish Shellfish Immunol. 21:170-175.
9. Sanchez, J. G., D. J. Speare, R. J. F. Markham, and S. R. M. Jones. 2001. Isolation of a Loma salmonae variant: biological characteristics and host range. J. Fish Biol. 59:427-441.
10. Sanchez, J. G., D. J. Speare, R. J. F. Markham, and S. R. M. Jones. 2001. Experimental vaccination of rainbow trout against Loma salmonae using a live low-virulence variant of L. salmonae. J. Fish Biol. 59:442-448.
11. Sanchez, J. G., D. J. Speare, and R. J. F. Markham. 2001. Altered tissue distribution of Loma salmonae: effects of natural and acquired resistance. J. Fish Dis. 24:33-40.
12. Sobottka, I., F. Igluaer, T. Schuler, C. Schmetz, G. S. Visvesvara, J. Albrecht, D. A. Schwartz, N. J. Pieniazek, K. Bartscht, R. Laufs, and J. Schottelius. 2001. Acute and long-term humoral immunity following active immunization of rabbits with inactivated spores of various Encephalitozoon species. Parasitol. Res. 87:1-6.
13. Sommerset, I., B. Krossoy, E. Biering, and P. Frost. 2005. Vaccines for fish in aquaculture. Expert Rev. Vaccines 4:89-191.
14. Speare, D. J., G. Ritter, and H. Schmidt. 1998. Quinine hydrochloride treatment delays xenoma formation and dissolution in rainbow trout challenged with Loma salmonae. J. Comp. Pathol. 119:459-465.
15. Speare, D. J., H. J. Beaman, and J. Daley. 1999. Effect of water temperature manipulation on a thermal unit predictive model for Loma salmonae. J. Fish Dis. 22:277-283.
16. Speare, D. J., F. Athanassopoulou, F. Daley, and J. G. Sanchez. 1999. A preliminary investigation of alternatives to fumagillin for the treatment of Loma salmonae infection in rainbow trout. J. Comp. Pathol. 121:241-248.