Genetic variants in PCSK9 in the Japanese population: Rare genetic variants in PCSK9 might collectively contribute to plasma LDL cholesterol levels in the general population

Atherosclerosis

Volumn 196, Issue 1, 2008, Pages 29-36

  Miyake, Yasuko ^a   Kimura, Rina ^a   Kokubo, Yoshihiro ^a   Okayama, Akira ^a   Tomoike, Hitonobu ^a   Yamamura, Taku ^b   Miyata, Toshiyuki ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

General population; Missense mutation; PCSK9; Plasma LDL cholesterol; Rare genetic variants

Indexed keywords

APOLIPOPROTEIN B100; HYPOCHOLESTEROLEMIC AGENT; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR;

ADULT; AGED; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE; GENETIC VARIABILITY; HUMAN; HYPERCHOLESTEROLEMIA; JAPANESE; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; NONSENSE MUTATION; PCSK9 GENE; POPULATION RESEARCH; PRIORITY JOURNAL; PROMOTER REGION;

ADULT; AGED; AGED, 80 AND OVER; CHOLESTEROL, LDL; FEMALE; HUMANS; HYPERCHOLESTEROLEMIA; JAPAN; MALE; MIDDLE AGED; MUTATION, MISSENSE; POLYMORPHISM, SINGLE NUCLEOTIDE; SERINE ENDOPEPTIDASES;

EID: 38049077373     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2006.12.035     Document Type: Article

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