Quantification of tenatoprazole in rat plasma by HPLC: Validation and its application to pharmacokinetic studies

Biomedical Chromatography

Volumn 21, Issue 12, 2007, Pages 1240-1244

  Nirogi, Ramakrishna ^a   Kandikere, Vishwottam ^a   Mudigonda, Koteshwara ^a   Bhyrapuneni, Gopinadh ^a  

^a SUVEN LIFE SCIENCES LTD   (India)

Author keywords

Oral dose; Pharmacokinetic disposition in rats; Tenatoprazole

Indexed keywords

BODY FLUIDS; PHARMACOKINETICS;

HPLC METHOD; ITS APPLICATIONS; ORAL DOSE; PHARMACOKINETIC DISPOSITION IN RAT; PHARMACOKINETIC STUDIES; PROTON-PUMP INHIBITORS; RAT PLASMA; SIMPLE++; TENATOPRAZOLE; UV DETECTION;

RATS;

BENATOPRAZOLE; ZONISAMIDE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG HALF LIFE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; QUANTITATIVE STUDY; RAT; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; VALIDITY;

RATTUS;

EID: 38049074778     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.875     Document Type: Article

References (10)

1. Domagala F, Ficheux H, Houin G and Barre J. Pharmacokinetics of tenatoprazole, a newly synthesized proton pump inhibitor, in healthy male Caucasian volunteers. Arzneimittel Forschung Drug Research 2006; 56: 33.
2. Galmiche JP, Varannes SB, Ducrotte P, Sacher-Huvelin S, Vavaseur F, Taccoen A, Fiorentini P and Homerin M. Tenatoprazole, a novel proton pump inhibitor with a prolonged plasma half-life: effects on intragastric pH and comparison with esomeprazole in healthy volunteers. Alimentary Pharmacology & Therapeutics 2004; 19: 655.
3. Gibaldi M and Perrier D. Pharmacokinetics, Swarbrick J (ed.). Marcel Dekker: New York, 1982; 409.
4. Liu P, Sun B, Lu X, Qin F and Li F. HPLC determination and pharmacokinetic study of tenatoprazole in dog plasma after oral administration of enteric-coated capsule. Biomedical Chromatography 2007; 21: 89.
5. Robinson M. Proton pump inhibitors: update on their role in acid-related gastrointestinal diseases. International Journal of Clinical Practice 2005; 59: 709.
6. Sachs G, Shin JM, Besancon M and Prinz C. The continuing development of gastric acid pump inhibitors. Alimentary Pharmacology and Therapeutics 1993; 7 (suppl. 1): 4.
7. + ATPase. Annual Reviews in Pharmacology and Toxicology 1995; 35: 277.
8. Saito S, Sebata N, Ishiwata T, Kinbara M and Morotome K. Pharmacokinetic studies of (±)-5-methoxy-2-(4-methoxy-3,5-dimethylpyrid-2-yl) methyl]sulfinyl]-1H-imidazo[4,5-b]pyridine (TU-199). Iyakuhin Kenkyu 1999; 30: 119.
9. +-ATPase in vitro and in vivo. Biochemical Pharmacology 2006; 71: 837.
10. +-ATPase inhibitor, on gastric acid secretion in dogs. Journal of Pharmacy and Pharmacology 1999; 51: 457.