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Volumn 371, Issue 1, 2008, Pages 206-215

A large animal model to evaluate the effects of Hsp90 inhibitors for the treatment of lung adenocarcinoma

Author keywords

Betaretroviruses; Jaagsiekte sheep retrovirus; Large animal models; Lung adenocaricnoma; Retroviruses; Sheep

Indexed keywords

17 DEMETHOXY 17 (2 DIMETHYLAMINOETHYLAMINO)GELDANAMYCIN; 2,3 DIHYDRO 2 OXO 3 (4,5,6,7 TETRAHYDRO 1H INDOL 2 YLMETHYLENE) 1H INDOLE 5 SULFONIC ACID DIMETHYLAMIDE; 4 (3 BROMOANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 6,7 DIMETHOXY 2 PHENYLQUINOXALINE; AG 2043; ANTIVIRUS AGENT; DAMNACANTHAL; EMODIN; GELDANAMYCIN; GENISTEIN INHIBITOR 1; GENISTEIN INHIBITOR 2; HEAT SHOCK PROTEIN 90; HERBIMYCIN A; JANUS KINASE INHIBITOR; LAVENDUSTIN C; PLATELET DERIVED GROWTH FACTOR RECEPTOR INHIBITOR 1; PLATELET DERIVED GROWTH FACTOR RECEPTOR INHIBITOR 2; PLATELET DERIVED GROWTH FACTOR RECEPTOR INHIBITOR 3; PROTEIN KINASE B; RADICICOL; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 2 KINASE INHIBITOR 3;

EID: 38049034421     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2007.09.041     Document Type: Article
Times cited : (17)

References (48)
  • 1
    • 0036842063 scopus 로고    scopus 로고
    • The Jaagsiekte sheep retrovirus envelope gene induces transformation of the avian fibroblast cell line DF-1 but does not require a conserved SH2 binding domain
    • Allen T.E., Sherrill K.J., Crispell S.M., Perrott M.R., Carlson J.O., and DeMartini J.C. The Jaagsiekte sheep retrovirus envelope gene induces transformation of the avian fibroblast cell line DF-1 but does not require a conserved SH2 binding domain. J. Gen. Virol. 83 Pt 11 (2002) 2733-2742
    • (2002) J. Gen. Virol. , vol.83 , Issue.PART 11 , pp. 2733-2742
    • Allen, T.E.1    Sherrill, K.J.2    Crispell, S.M.3    Perrott, M.R.4    Carlson, J.O.5    DeMartini, J.C.6
  • 3
    • 33646114761 scopus 로고    scopus 로고
    • Hsp90 inhibitors: small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation
    • Blagg B.S., and Kerr T.D. Hsp90 inhibitors: small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation. Med. Res. Rev. 26 3 (2006) 310-338
    • (2006) Med. Res. Rev. , vol.26 , Issue.3 , pp. 310-338
    • Blagg, B.S.1    Kerr, T.D.2
  • 4
    • 0034458943 scopus 로고    scopus 로고
    • SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling
    • Blake R.A., Broome M.A., Liu X., Wu J., Gishizky M., Sun L., and Courtneidge S.A. SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling. Mol. Cell. Biol. 20 23 (2000) 9018-9027
    • (2000) Mol. Cell. Biol. , vol.20 , Issue.23 , pp. 9018-9027
    • Blake, R.A.1    Broome, M.A.2    Liu, X.3    Wu, J.4    Gishizky, M.5    Sun, L.6    Courtneidge, S.A.7
  • 5
    • 0035872199 scopus 로고    scopus 로고
    • Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation
    • Brognard J., Clark A.S., Ni Y., and Dennis P.A. Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation. Cancer Res. 61 10 (2001) 3986-3997
    • (2001) Cancer Res. , vol.61 , Issue.10 , pp. 3986-3997
    • Brognard, J.1    Clark, A.S.2    Ni, Y.3    Dennis, P.A.4
  • 6
    • 33746808547 scopus 로고    scopus 로고
    • Expression of the Jaagsiekte sheep retrovirus envelope glycoproteins is sufficient to induce lung tumor in sheep
    • Caporale M., Cousens C., Centorame P., Pinoni C., De las Heras M., and Palmarini M. Expression of the Jaagsiekte sheep retrovirus envelope glycoproteins is sufficient to induce lung tumor in sheep. J. Virol. 80 (2006) 8030-8037
    • (2006) J. Virol. , vol.80 , pp. 8030-8037
    • Caporale, M.1    Cousens, C.2    Centorame, P.3    Pinoni, C.4    De las Heras, M.5    Palmarini, M.6
  • 7
    • 0029011834 scopus 로고
    • Analysis of heat-shock protein expression in myeloid leukaemia cells by flow cytometry
    • Chant I.D., Rose P.E., and Morris A.G. Analysis of heat-shock protein expression in myeloid leukaemia cells by flow cytometry. Br. J. Haematol. 90 1 (1995) 163-168
    • (1995) Br. J. Haematol. , vol.90 , Issue.1 , pp. 163-168
    • Chant, I.D.1    Rose, P.E.2    Morris, A.G.3
  • 8
    • 0038027024 scopus 로고    scopus 로고
    • Transformation of rodent fibroblasts by the Jaagsiekte sheep retrovirus envelope is receptor independent and does not require the surface domain
    • Chow Y.H., Alberti A., Mura M., Pretto C., Murcia P., Albritton L.M., and Palmarini M. Transformation of rodent fibroblasts by the Jaagsiekte sheep retrovirus envelope is receptor independent and does not require the surface domain. J. Virol. 77 11 (2003) 6341-6350
    • (2003) J. Virol. , vol.77 , Issue.11 , pp. 6341-6350
    • Chow, Y.H.1    Alberti, A.2    Mura, M.3    Pretto, C.4    Murcia, P.5    Albritton, L.M.6    Palmarini, M.7
  • 9
    • 33745215858 scopus 로고    scopus 로고
    • Integrative pharmacology and drug discovery-is the tide finally turning?
    • Collis M.C. Integrative pharmacology and drug discovery-is the tide finally turning?. Nat. Rev. Drug Discov. 5 5 (2006) 377-379
    • (2006) Nat. Rev. Drug Discov. , vol.5 , Issue.5 , pp. 377-379
    • Collis, M.C.1
  • 10
    • 33745841540 scopus 로고    scopus 로고
    • In-situ demonstration of mitogen-activated protein kinase Erk 1/2 signalling pathway in contagious respiratory tumours of sheep and goats
    • De Las Heras M., Ortin A., Benito A., Summers C., Ferrer L.M., and Sharp J.M. In-situ demonstration of mitogen-activated protein kinase Erk 1/2 signalling pathway in contagious respiratory tumours of sheep and goats. J. Comp. Pathol. 135 1 (2006) 1-10
    • (2006) J. Comp. Pathol. , vol.135 , Issue.1 , pp. 1-10
    • De Las Heras, M.1    Ortin, A.2    Benito, A.3    Summers, C.4    Ferrer, L.M.5    Sharp, J.M.6
  • 11
    • 20344405446 scopus 로고    scopus 로고
    • DNA methylation disturbances as novel therapeutic target in lung cancer: preclinical and clinical results
    • Digel W., and Lubbert M. DNA methylation disturbances as novel therapeutic target in lung cancer: preclinical and clinical results. Crit. Rev. Oncol. Hematol. 55 1 (2005) 1-11
    • (2005) Crit. Rev. Oncol. Hematol. , vol.55 , Issue.1 , pp. 1-11
    • Digel, W.1    Lubbert, M.2
  • 12
    • 33746875575 scopus 로고    scopus 로고
    • Mouse models of lung cancer
    • Dutt A., and Wong K.K. Mouse models of lung cancer. Clin. Cancer Res. 12 14 Pt 2 (2006) 4396s-4402s
    • (2006) Clin. Cancer Res. , vol.12 , Issue.14 PART 2
    • Dutt, A.1    Wong, K.K.2
  • 14
    • 0034282535 scopus 로고    scopus 로고
    • Genome-wide allelotyping of lung cancer identifies new regions of allelic loss, differences between small cell lung cancer and non-small cell lung cancer, and loci clustering
    • Girard L., Zochbauer-Muller S., Virmani A.K., Gazdar A.F., and Minna J.D. Genome-wide allelotyping of lung cancer identifies new regions of allelic loss, differences between small cell lung cancer and non-small cell lung cancer, and loci clustering. Cancer Res. 60 17 (2000) 4894-4906
    • (2000) Cancer Res. , vol.60 , Issue.17 , pp. 4894-4906
    • Girard, L.1    Zochbauer-Muller, S.2    Virmani, A.K.3    Gazdar, A.F.4    Minna, J.D.5
  • 15
    • 33746823751 scopus 로고    scopus 로고
    • Mutational analysis of the cytoplasmic tail of Jaagsiekte sheep retrovirus envelope protein
    • Hull S., and Fan H. Mutational analysis of the cytoplasmic tail of Jaagsiekte sheep retrovirus envelope protein. J. Virol. 80 16 (2006) 8069-8080
    • (2006) J. Virol. , vol.80 , Issue.16 , pp. 8069-8080
    • Hull, S.1    Fan, H.2
  • 16
    • 38049073593 scopus 로고    scopus 로고
    • Jassim, F.A. (1988). PhD Thesis. University of Edinburgh, Edinburgh, UK.
  • 17
    • 0023442081 scopus 로고
    • Three-step procedure for isolation of epithelial cells from the lungs of sheep with Jaagsiekte
    • Jassim F.A., Sharp J.M., and Marinello P.D. Three-step procedure for isolation of epithelial cells from the lungs of sheep with Jaagsiekte. Res. Vet. Sci. 43 3 (1987) 407-409
    • (1987) Res. Vet. Sci. , vol.43 , Issue.3 , pp. 407-409
    • Jassim, F.A.1    Sharp, J.M.2    Marinello, P.D.3
  • 18
    • 0141484615 scopus 로고    scopus 로고
    • A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
    • Kamal A., Thao L., Sensintaffar J., Zhang L., Boehm M.F., Fritz L.C., and Burrows F.J. A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors. Nature 425 6956 (2003) 407-410
    • (2003) Nature , vol.425 , Issue.6956 , pp. 407-410
    • Kamal, A.1    Thao, L.2    Sensintaffar, J.3    Zhang, L.4    Boehm, M.F.5    Fritz, L.C.6    Burrows, F.J.7
  • 21
    • 0036072924 scopus 로고    scopus 로고
    • Ras/Raf signalling and emerging pharmacotherapeutic targets
    • Kolch W. Ras/Raf signalling and emerging pharmacotherapeutic targets. Expert Opin. Pharmacother. 3 6 (2002) 709-718
    • (2002) Expert Opin. Pharmacother. , vol.3 , Issue.6 , pp. 709-718
    • Kolch, W.1
  • 22
    • 0038758938 scopus 로고    scopus 로고
    • Putative phosphatidylinositol 3-kinase (PI3K) binding motifs in ovine betaretrovirus Env proteins are not essential for rodent fibroblast transformation and PI3K/Akt activation
    • Liu S.L., Lerman M.I., and Miller A.D. Putative phosphatidylinositol 3-kinase (PI3K) binding motifs in ovine betaretrovirus Env proteins are not essential for rodent fibroblast transformation and PI3K/Akt activation. J. Virol. 77 14 (2003) 7924-7935
    • (2003) J. Virol. , vol.77 , Issue.14 , pp. 7924-7935
    • Liu, S.L.1    Lerman, M.I.2    Miller, A.D.3
  • 23
    • 0035836679 scopus 로고    scopus 로고
    • Direct transformation of rodent fibroblasts by Jaagsiekte sheep retrovirus DNA
    • Maeda N., Palmarini M., Murgia C., and Fan H. Direct transformation of rodent fibroblasts by Jaagsiekte sheep retrovirus DNA. Proc. Natl. Acad. Sci. U. S. A. 98 8 (2001) 4449-4454
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , Issue.8 , pp. 4449-4454
    • Maeda, N.1    Palmarini, M.2    Murgia, C.3    Fan, H.4
  • 24
    • 0141682000 scopus 로고    scopus 로고
    • Transformation of mouse fibroblasts by Jaagsiekte sheep retrovirus envelope does not require phosphatidylinositol 3-kinase
    • Maeda N., Inoshima Y., Fruman D.A., Brachmann S.M., and Fan H. Transformation of mouse fibroblasts by Jaagsiekte sheep retrovirus envelope does not require phosphatidylinositol 3-kinase. J. Virol. 77 (2003) 9951-9959
    • (2003) J. Virol. , vol.77 , pp. 9951-9959
    • Maeda, N.1    Inoshima, Y.2    Fruman, D.A.3    Brachmann, S.M.4    Fan, H.5
  • 25
    • 15244358146 scopus 로고    scopus 로고
    • Roles of the Ras-MEK-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt-mTOR pathways in Jaagsiekte sheep retrovirus-induced transformation of rodent fibroblast and epithelial cell lines
    • Maeda N., Fu W., Ortin A., de las Heras M., and Fan H. Roles of the Ras-MEK-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt-mTOR pathways in Jaagsiekte sheep retrovirus-induced transformation of rodent fibroblast and epithelial cell lines. J. Virol. 79 7 (2005) 4440-4450
    • (2005) J. Virol. , vol.79 , Issue.7 , pp. 4440-4450
    • Maeda, N.1    Fu, W.2    Ortin, A.3    de las Heras, M.4    Fan, H.5
  • 27
    • 0036924728 scopus 로고    scopus 로고
    • Pathology of human bronchioloalveolar carcinoma and its relationship to the ovine disease
    • Mornex J.F., Thivolet F., De las Heras M., and Leroux C. Pathology of human bronchioloalveolar carcinoma and its relationship to the ovine disease. Curr. Top. Microbiol. Immunol. 275 (2003) 225-248
    • (2003) Curr. Top. Microbiol. Immunol. , vol.275 , pp. 225-248
    • Mornex, J.F.1    Thivolet, F.2    De las Heras, M.3    Leroux, C.4
  • 28
    • 0035824071 scopus 로고    scopus 로고
    • Retrovirus-induced ovine pulmonary adenocarcinoma, an animal model for lung cancer
    • Palmarini M., and Fan H. Retrovirus-induced ovine pulmonary adenocarcinoma, an animal model for lung cancer. J. Natl. Cancer Inst. 93 21 (2001) 1603-1614
    • (2001) J. Natl. Cancer Inst. , vol.93 , Issue.21 , pp. 1603-1614
    • Palmarini, M.1    Fan, H.2
  • 29
    • 0036920594 scopus 로고    scopus 로고
    • Molecular biology of Jaagsiekte sheep retrovirus
    • Palmarini M., and Fan H. Molecular biology of Jaagsiekte sheep retrovirus. Curr. Top. Microbiol. Immunol. 275 (2003) 81-115
    • (2003) Curr. Top. Microbiol. Immunol. , vol.275 , pp. 81-115
    • Palmarini, M.1    Fan, H.2
  • 30
    • 0032796337 scopus 로고    scopus 로고
    • Jaagsiekte sheep retrovirus is necessary and sufficient to induce a contagious lung cancer in sheep
    • Palmarini M., Sharp J.M., De las Heras M., and Fan H. Jaagsiekte sheep retrovirus is necessary and sufficient to induce a contagious lung cancer in sheep. J. Virol. 73 (1999) 6964-6972
    • (1999) J. Virol. , vol.73 , pp. 6964-6972
    • Palmarini, M.1    Sharp, J.M.2    De las Heras, M.3    Fan, H.4
  • 31
    • 0034767584 scopus 로고    scopus 로고
    • A phosphatidylinositol 3-kinase docking site in the cytoplasmic tail of the Jaagsiekte sheep retrovirus transmembrane protein is essential for envelope-induced transformation of NIH 3T3 cells
    • Palmarini M., Maeda N., Murgia C., De-Fraja C., Hofacre A., and Fan H. A phosphatidylinositol 3-kinase docking site in the cytoplasmic tail of the Jaagsiekte sheep retrovirus transmembrane protein is essential for envelope-induced transformation of NIH 3T3 cells. J. Virol. 75 22 (2001) 11002-11009
    • (2001) J. Virol. , vol.75 , Issue.22 , pp. 11002-11009
    • Palmarini, M.1    Maeda, N.2    Murgia, C.3    De-Fraja, C.4    Hofacre, A.5    Fan, H.6
  • 33
    • 0035836625 scopus 로고    scopus 로고
    • Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for Jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation
    • Rai S.K., Duh F.M., Vigdorovich V., Danilkovitch-Miagkova A., Lerman M.I., and Miller A.D. Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for Jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation. Proc. Natl. Acad. Sci. U. S. A. 98 8 (2001) 4443-4448
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , Issue.8 , pp. 4443-4448
    • Rai, S.K.1    Duh, F.M.2    Vigdorovich, V.3    Danilkovitch-Miagkova, A.4    Lerman, M.I.5    Miller, A.D.6
  • 34
    • 0037899935 scopus 로고    scopus 로고
    • Improving the evaluation of new cancer treatments: challenges and opportunities
    • Rothenberg M.L., Carbone D.P., and Johnson D.H. Improving the evaluation of new cancer treatments: challenges and opportunities. Nat. Rev., Cancer 3 4 (2003) 303-309
    • (2003) Nat. Rev., Cancer , vol.3 , Issue.4 , pp. 303-309
    • Rothenberg, M.L.1    Carbone, D.P.2    Johnson, D.H.3
  • 35
    • 7544241997 scopus 로고    scopus 로고
    • Successful induction of ovine pulmonary adenocarcinoma in lambs of different ages and detection of viraemia during the preclinical period
    • Salvatori D., Gonzalez L., Dewar P., Cousens C., de las Heras M., Dalziel R.G., and Sharp J.M. Successful induction of ovine pulmonary adenocarcinoma in lambs of different ages and detection of viraemia during the preclinical period. J. Gen. Virol. 85 Pt 11 (2004) 3319-3324
    • (2004) J. Gen. Virol. , vol.85 , Issue.PART 11 , pp. 3319-3324
    • Salvatori, D.1    Gonzalez, L.2    Dewar, P.3    Cousens, C.4    de las Heras, M.5    Dalziel, R.G.6    Sharp, J.M.7
  • 36
    • 0030750217 scopus 로고    scopus 로고
    • Expression of heat shock protein 72 in renal cell carcinoma: possible role and prognostic implications in cancer patients
    • Santarosa M., Favaro D., Quaia M., and Galligioni E. Expression of heat shock protein 72 in renal cell carcinoma: possible role and prognostic implications in cancer patients. Eur. J. Cancer 33 6 (1997) 873-877
    • (1997) Eur. J. Cancer , vol.33 , Issue.6 , pp. 873-877
    • Santarosa, M.1    Favaro, D.2    Quaia, M.3    Galligioni, E.4
  • 37
    • 0034718540 scopus 로고    scopus 로고
    • Modulation of Akt kinase activity by binding to Hsp90
    • Sato S., Fujita N., and Tsuruo T. Modulation of Akt kinase activity by binding to Hsp90. Proc. Natl. Acad. Sci. U. S. A. 97 20 (2000) 10832-10837
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , Issue.20 , pp. 10832-10837
    • Sato, S.1    Fujita, N.2    Tsuruo, T.3
  • 39
    • 0021059564 scopus 로고
    • Rapid transmission of sheep pulmonary adenomatosis (Jaagsiekte) in young lambs. Brief report
    • Sharp J.M., Angus K.W., Gray E.W., and Scott F.M. Rapid transmission of sheep pulmonary adenomatosis (Jaagsiekte) in young lambs. Brief report. Arch. Virol. 78 1-2 (1983) 89-95
    • (1983) Arch. Virol. , vol.78 , Issue.1-2 , pp. 89-95
    • Sharp, J.M.1    Angus, K.W.2    Gray, E.W.3    Scott, F.M.4
  • 41
    • 0035960717 scopus 로고    scopus 로고
    • Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity
    • Timpson P., Jones G.E., Frame M.C., and Brunton V.G. Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity. Curr. Biol. 11 23 (2001) 1836-1846
    • (2001) Curr. Biol. , vol.11 , Issue.23 , pp. 1836-1846
    • Timpson, P.1    Jones, G.E.2    Frame, M.C.3    Brunton, V.G.4
  • 42
    • 33745445348 scopus 로고    scopus 로고
    • Association of RON tyrosine kinase with the Jaagsiekte sheep retrovirus envelope glycoprotein
    • Varela M., Chow Y.H., Sturkie C., Murcia P., and Palmarini M. Association of RON tyrosine kinase with the Jaagsiekte sheep retrovirus envelope glycoprotein. Virology 350 2 (2006) 347-357
    • (2006) Virology , vol.350 , Issue.2 , pp. 347-357
    • Varela, M.1    Chow, Y.H.2    Sturkie, C.3    Murcia, P.4    Palmarini, M.5
  • 44
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase AKT pathway in human cancer
    • Vivanco I., and Sawyers C.L. The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat. Rev., Cancer 2 7 (2002) 489-501
    • (2002) Nat. Rev., Cancer , vol.2 , Issue.7 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 45
    • 17244380460 scopus 로고    scopus 로고
    • Sheep retrovirus structural protein induces lung tumours
    • Wootton S.K., Halbert C.L., and Miller A.D. Sheep retrovirus structural protein induces lung tumours. Nature 434 7035 (2005) 904-907
    • (2005) Nature , vol.434 , Issue.7035 , pp. 904-907
    • Wootton, S.K.1    Halbert, C.L.2    Miller, A.D.3
  • 46
    • 1542298267 scopus 로고    scopus 로고
    • Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone
    • Workman P. Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone. Cancer Lett. 206 2 (2004) 149-157
    • (2004) Cancer Lett. , vol.206 , Issue.2 , pp. 149-157
    • Workman, P.1
  • 47
    • 0026664393 scopus 로고
    • High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells
    • Yufu Y., Nishimura J., and Nawata H. High constitutive expression of heat shock protein 90 alpha in human acute leukemia cells. Leuk. Res. 16 6-7 (1992) 597-605
    • (1992) Leuk. Res. , vol.16 , Issue.6-7 , pp. 597-605
    • Yufu, Y.1    Nishimura, J.2    Nawata, H.3
  • 48
    • 33847009160 scopus 로고    scopus 로고
    • SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines
    • Zhang J., Kalyankrishna S., Wislez M., Thilaganathan N., Saigal B., Wei W., Ma L., Wistuba II, Johnson F.M., and Kurie J.M. SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines. Am. J. Pathol. 170 1 (2007) 366-376
    • (2007) Am. J. Pathol. , vol.170 , Issue.1 , pp. 366-376
    • Zhang, J.1    Kalyankrishna, S.2    Wislez, M.3    Thilaganathan, N.4    Saigal, B.5    Wei, W.6    Ma, L.7    Wistuba II8    Johnson, F.M.9    Kurie, J.M.10


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