Polymorphisms of cpb multicopy genes in the Leishmania (Leishmania) donovani complex

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 102, Issue 2, 2008, Pages 105-106

  Hide, M ^a   Banuls A L ^a  

^a INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT   (France)

Author keywords

COOH terminal extension; Cysteine protease b; Leishmania donovani; Leishmania infantum; Polymorphism; Visceral leishmaniasis

Indexed keywords

CYSTEINE PROTEINASE; CYSTEINE PROTEINASE B; EPITOPE; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; GENE CLUSTER; GENE DUPLICATION; GENE EXPRESSION; GENE FUNCTION; GENE SEQUENCE; GENE STRUCTURE; GENETIC VARIABILITY; HOST PARASITE INTERACTION; IMMUNOGENICITY; LEISHMANIA DONOVANI; MOLECULAR EVOLUTION; NONHUMAN; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN LEISHMANIASIS; TANDEM REPEAT; VISCERAL LEISHMANIASIS;

ANIMALS; CYSTEINE ENDOPEPTIDASES; EVOLUTION, MOLECULAR; ISOENZYMES; LEISHMANIA DONOVANI; LEISHMANIA INFANTUM; POLYMORPHISM, SINGLE NUCLEOTIDE;

LEISHMANIA DONOVANI; LEISHMANIA INFANTUM;

EID: 38049018065     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trstmh.2007.09.013     Document Type: Review

References (5)

1. Hide M., Bras-Goncalves R., and Bañuls A.-L. Specific cpb copies within the Leishmania donovani complex: evolutionary interpretations and potential clinical implications in humans. Parasitology 134 (2007) 379-389
2. Mottram J.C., Frame M.J., Brooks D.R., Tetley L., Hutchison J.E., Souza A.E., and Coombs G.H. The multiple cpb cysteine proteinase genes of Leishmania mexicana encode isoenzymes that differ in their stage regulation and substrate preferences. J. Biol. Chem. 272 (1997) 14285-14293
3. Mundodi V., Somanna A., Farrell P.J., and Gedamu L. Genomic organization and functional expression of differentially regulated cysteine protease genes of Leishmania donovani complex. Gene 282 (2002) 257-265
4. Nakhaee A., Taheri T., Taghikhani M., Mohebali M., Salmanian A.H., Fasel N., and Rafati S. Humoral and cellular immune responses against type I cysteine proteinase of Leishmania infantum are higher in asymptomatic than symptomatic dogs selected from a naturally infected population. Vet. Parasitol. 119 (2004) 107-123
5. Rafati S., Nakhaee A., Taheri T., Ghashghaii A., Salmanian A.H., Jimenez M., Mohebali M., Masina S., and Fasel N. Expression of cysteine proteinase type I and II of Leishmania infantum and their recognition by sera during canine and human visceral leishmaniasis. Exp. Parasitol. 103 (2003) 143-151