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Recker R, Lappe J, Davies KM, et al.: Bone remodeling increases substantially in the years after menopause and remains increased in older osteoporosis patients. J Bone Miner Res 2004, 19:1628-1633.
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• Donovan MA, Dempster D, Zhou H, et al.: Low bone formation in premenopausal women with idiopathic osteoporosis. J Clin Endocrinol Metab 2005, 90:3331-3336. This article describes the bone histologic abnormalities in premenopausal women with idiopathic osteoporosis, finding that women with idiopathic osteoporosis have lower bone formation rate and longer resorption period than normal controls.
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• Donovan MA, Dempster D, Zhou H, et al.: Low bone formation in premenopausal women with idiopathic osteoporosis. J Clin Endocrinol Metab 2005, 90:3331-3336. This article describes the bone histologic abnormalities in premenopausal women with idiopathic osteoporosis, finding that women with idiopathic osteoporosis have lower bone formation rate and longer resorption period than normal controls.
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16
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Alendronate and estrogen effects in postmenopausal women with low bone mineral density. Alendronate/Estrogen Study Group
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•• Arlot M, Meunier PJ, Boivin G, et al: Differential effects of teriparatide and alendronate on bone remodeling in postmenopausal women assessed by histomorphometric parameters. J Bone Miner Res 2005, 20:1244-1253. This study compares the effects of 6 or 18 months' treatment with teriparatide or alendronate on bone, showing that teriparatide treatment increases bone formation and to a lesser degree bone resorption when compared with alendronate treatment.
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•• Arlot M, Meunier PJ, Boivin G, et al: Differential effects of teriparatide and alendronate on bone remodeling in postmenopausal women assessed by histomorphometric parameters. J Bone Miner Res 2005, 20:1244-1253. This study compares the effects of 6 or 18 months' treatment with teriparatide or alendronate on bone, showing that teriparatide treatment increases bone formation and to a lesser degree bone resorption when compared with alendronate treatment.
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•• Lindsay R, Zhou H, Cosman F, et al.: Effects of a one-month treatment with PTH(1-34) on bone formation on cancellous, endocortical, and periosteal surfaces of the human ilium. J Bone Miner Res 2007, 22:495-502. This article investigates the mechanisms of the anabolic action of teriparatide on bone, finding that teriparatide stimulates bone formation at ongoing remodeling sites and increases osteoblast apoptosis, which may reflect enhanced turnover of the osteoblastic population.
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•• Lindsay R, Zhou H, Cosman F, et al.: Effects of a one-month treatment with PTH(1-34) on bone formation on cancellous, endocortical, and periosteal surfaces of the human ilium. J Bone Miner Res 2007, 22:495-502. This article investigates the mechanisms of the anabolic action of teriparatide on bone, finding that teriparatide stimulates bone formation at ongoing remodeling sites and increases osteoblast apoptosis, which may reflect enhanced turnover of the osteoblastic population.
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Comparison of mineral quality and quantity in iliac crest biopsies from high- and low-turnover osteoporosis: An FT-IR microspectroscopic investigation
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Boskey AL, DiCarlo E, Paschalis E, et al.: Comparison of mineral quality and quantity in iliac crest biopsies from high- and low-turnover osteoporosis: an FT-IR microspectroscopic investigation. Osteoporos Int 2005, 16:2031-2038. This article reports mineral quality in controls and osteoporotic patients with high or low bone turnover.
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