Effect of treatment with Xuebijing injection on serum inflammatory mediators and Th1/2 of spleen in rats with sepsis

Chinese Critical Care Medicine

Volumn 18, Issue 11, 2006, Pages 673-676

  Zhang, Shu Wen ^a   Sun, Cheng Dong ^a   Wen, Yan ^a   Yin, Cheng Hong ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Immune function; Inflammatory mediators; Interleukin 10; Sepsis; T lymphocyte; Tumor necrosis factor ; Xuebijing injection

Indexed keywords

CHINESE DRUG; INTERLEUKIN 10; LEVOFLOXACIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; XUEBIJING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD SAMPLING; CECUM; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; IMMUNOLOGY; NONHUMAN; PATHOLOGY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SEPSIS; TH1 CELL; TH2 CELL;

ANIMALS; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; INFLAMMATION MEDIATORS; INTERLEUKIN-10; LIVER; MALE; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SEPSIS; SPLEEN; T-LYMPHOCYTES, HELPER-INDUCER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 37849188151     PISSN: 10030603     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Murphy K M, Ouyang W, Farrar J D, et al. Signaling and transcription in T helper development[J]. Annu Rev Immunol, 2000,18:451-494.
2. Dong C, Juedes A E, Temann U A,et al. ICOS co-stimulatory receptor is essential for T - cell activation and function [J]. Nature,2001,409:97-101.
3. Abbas A K, Murphy K M, Sher A. Functional diversity of helper T lymphocytes[J]. Nature,1996,383:787-793.
4. Lederer J A, Rodrick M L, Mannick J A. The effects of injury on the adaptive immune response[J]. Shock,1999,11:153-159.
5. +T lymphocytes during polymicrobial sepsis is mediated by Fas ligand and not endotoxin [J]. Immunology, 1999, 97: 45-55.
6. Heidecke C D, Hensler T, Weighardt H, et al. Selective defects of T lymphocyte function in patients with lethal intraabdominal infection[J]. Am J Surg,1999,178:288-292.
7. Green D R, Beere H M. Apoptosis:gone but not forgotten[J]. Nature,2000,405:28-29.
8. Munford R S, Pugin J. Normal responses to injury prevent systemic inflammation and can be immunosuppressive[J]. Am J Respir Crit Care Med,2001,163:316-321.
9. Bone R C. Immunologic dissonance:a continuing evolution in our understanding of the systemic inflammatory response syndrome(SIRS) and the multiple organ dysfunction syndrome (MODS)[J]. Ann Intern Med,1996,125:680-687.