Pertussis toxin B-oligomer suppresses human immunodeficiency virus-1 Tat-induced neuronal apoptosis through feedback inhibition of phospholipase C-β by protein kinase C

Neuroscience

Volumn 151, Issue 2, 2008, Pages 525-532

  Jajoo, S ^a   Mukherjea, D ^a   Brewer, G J ^a   Ramkumar, V ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

apoptosis; calcium; HIV neurotoxicity; HIV 1 Tat; pertussis toxin B oligomer; phospholipase C

Indexed keywords

BENZENESULFONAMIDE DERIVATIVE; BISINDOLYLMALEIMIDE; BRADYKININ; CALCIUM ION; CASPASE 3; ENZYME ACTIVATOR; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OLIGOMER; PERTUSSIS TOXIN; PERTUSSIS TOXIN B; PHORBOL DIBUTYRATE; PHOSPHOLIPASE C; PHOSPHOLIPASE C BETA; PROTEIN BAX; PROTEIN KINASE C; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CELL STRAIN; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; NEGATIVE FEEDBACK; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; RAT;

ADENOSINE DIPHOSPHATE RIBOSE; ANIMALS; APOPTOSIS; CALCIUM; CEREBRAL CORTEX; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; FEEDBACK, BIOCHEMICAL; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; IMMUNOHISTOCHEMISTRY; NEURONS; PC12 CELLS; PERTUSSIS TOXIN; PHOSPHOLIPASE C BETA; PROTEIN KINASE C; RATS; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

EID: 37849042455     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2007.11.010     Document Type: Article

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