Development and disappearance of wavy ribs caused by azosemide in the mouse fetus

Congenital Anomalies

Volumn 37, Issue 3, 1997, Pages 241-249

  Kumazawa, Toshihiko ^a   Kato, Tatsuma ^a   Hayasaka, Kuo ^b  

^a SANWA KAGAKU KENKYUSHO CO LTD   (Japan)

^b Kumamoto Primates Park   (Japan)

Author keywords

Azosemide; Calcification; Mice; Ossification; Wavy ribs

Indexed keywords

EID: 37849040596     PISSN: 09143505     EISSN: 17414520     Source Type: Journal    
DOI: 10.1111/j.1741-4520.1997.tb00549.x     Document Type: Article

References (14)

1. Bisaz, S., Schenk, R., Kunin, A.S., Russell, R.G.G., Muhlbauer, R. and Fleisch, H. (1975) The comparative effects of vitamin D deficiency and ethane- I-hydroxy-1, 1-diphasphonate administration on the histology and glycolysis of chick epiphyseal and articular cartilage. Calcif. Tissue Res., 19: 139-152.
2. Butter, H.S., Dupuis, I. and Khera, K.S. (1978) Dimethadione- induced fetotoxicity in rats. Toxicology, 9: 155-164.
3. Eguchi, M., Yamaguchi, T., Shiota, E. and Handa, S. (1982) Fault of ossification and calcification and angular deformities of long bones in the mouse fetuses caused by high doses of ethane-1-hydroxy-I, 1-diphosphonate (EHDP) during pregnancy. Cong. Anom., 22: 47-52.
4. Hayasaka, I., Uchiyama, K., Murakami, K., Kato, Z., Tamaki, F., Shihata, T., Sugawara, T. and Hayashi. M. (1984) Teratogenicity of azosemide, a loop diuretic, in rats, mice and rabbits. Cong. Anom., 24: 111-121.
5. Hayasaka, I., Tamaki, F., Uchiyama, K., Kato, Z. and Murakami, K. (1985) Azosemide-induced fetal wavy ribs and their disappearance after birth in rats. Cong. Anom., 25: 121-127.
6. Kóssa, J. von. (1901) Uber die im Organismus künstlich erzeugharen Verkalkungen. Beitr. Path. Anat. , 29: 163-202.
7. Larsson, A®. and Larsson, S.-E. (1976) Light microscopic and ultrastructural observations on the short-term effects of ethylene-1-hydroxy-1, 1-diphosphonate (EHDP) on rat tibia epiphysis. Acta path. microbiol. Scand. Sect. A, 84: 17-27.
8. Nakatsuka, T. (1988) Role of myometrial constriction in the induction of wavy ribs in rat fetuses. Teratology, 37: 329-334.
9. Nishimura, M.. Iizuka, M., Iwaki, S. and Kast, A. (1982) Repairability of drug-induced "wavy ribs" in rat offspring. Arzneim.-Forsch./Drug Res., 32: 1518-1522.
10. Posner, AS. (1978) The chemistry of bone mineral. Hosp. Joint Dis., 39: 126-144.
11. Robertson, R.T., Minsker, D.H., Bokelman, D.L.. Durand, G. and Conquet, P. (1981) Potassium loss as a causative factor for skeletal malformations in rats produced by indacrinone: A new investigational loop diuretic. Toxicol. Appl. Pharmacol., 60: 142-150.
12. Sterz, H., Sponer. G., Neubert, P. and Hebold, G. (1985) A postulated mechanism of β-sympathomimetic induction of rib and limb anomalies in rat fetuses. Teratology, 31: 401-412.
13. Wassersug, R.J. (1976) A procedure for differential staining of cartilage and bone in whole formalin-fixed vertebrates. Stain Technol., 51: 131-134.
14. Watanabe, K. and Fishman, W.H. (1964) Application of the stereospecific inhibitor L-phenylalanine to the enzymorphology of intestinal alkaline phosphatase. J. Histochem. Cytochem.. 12: 252-260.