Comparative evaluation of effectiveness of adapalene and azithromycin, alone or in combination, in acne vulgaris

Indian Journal of Dermatology

Volumn 52, Issue 4, 2007, Pages 179-183

  Ghoshal, Loknath ^a   Banerjee, Sabyasachi ^a,b   Ghosh, Sadhan ^a   Gangopadhyay, Dwijendra ^a   Jana, Sukumar ^a  

^a CALCUTTA NATIONAL MEDICAL COLLEGE   (India)

^b NONE   (India)

Author keywords

Acne; Adapalene; Azithromycin; Inflammatory

Indexed keywords

ADAPALENE; AZITHROMYCIN;

ACNE VULGARIS; ADOLESCENT; ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; DRUG EFFICACY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; RANDOMIZED CONTROLLED TRIAL; STATISTICAL ANALYSIS; THERAPY EFFECT; TREATMENT DURATION; TREATMENT OUTCOME; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT;

EID: 37849026184     PISSN: 00195154     EISSN: None     Source Type: Journal    
DOI: 10.4103/0019-5154.37721     Document Type: Article

References (12)

1. Bergfield WF. Topical retinoids in the management of acne vulgaris. J Drug Dev Clin Pract 1996;8:151-60.
2. th ed. Lippincott Raven: Philadelphia; 1997. p. 403-4.
3. Thielitz A, Helmdach M, Röpke EM, Gollnick H. Lipid analysis of follicular casts from cyanoacrylate strips as a new method for studying therapeutic effects of anti acne agents. Br J Dermatol 2001;145:19-27.
4. Neu HC. Clinical microbiology of azithromycin. Am J Med 1991;91:12S-8S.
5. Stern RS. The prevalence of acne on the basis of acne on the basis of physical examination. J Am Acad Dermatol 1992;26:931-5.
6. Michel S, Jomard A, Demarchez M. Pharmacology of adapalene. Br J Dermatol 1998;139:3-7.
7. Cunliffe WJ, Danby FW, Dunlap F, Gold MH, Gratton D, Greenspan A. Randomized, controlled trial of the efficacy and safety of adapalene gel 0.1% and tretinoin cream 0.05% in patients with acne vulgaris. Eur J Dermatol 2002;12:350-4.
8. Cunliffe WJ, Poncet M, Loesche C, Verschoore M. A comparison of the efficacy and tolerability of adapalene 0.1% gel versus tretinoin 0.025% gel in patients with acne vulgaris: A metaanalysis of five randomized trials. Br J Dermatol 1998;139:48-56.
9. Ellis CN, Millikan LE, Smith EB, Chalker DM, Swinyer LJ, Katz IH, et al. Comparison of adapalene 0.1% solution and tretinoin 0.025% gel in the topical treatment of acne vulgaris. Br J Dermatol 1998;139:41-7.
10. Cunliffe WJ, Meynadier J, Alirezai M, George SA, Coutts I, Roseeuw DI, et al. Is combined oral and topical therapy better than oral therapy alone in patients with moderate to moderately severe acne vulgaris? A comparison of the efficacy and safety of lymecycline plus adapalene gel 0.1%, versus lymecycline plus gel vehicle. J Am Acad Dermatol 2003;49:S218-26.
11. Eady EA. Bacterial resistance in acne. Dermatology 1998;196: 59-66.
12. Espersen F. Resistance to antibiotics used in dermatological practice. Br J Dermatol 1998;139:4-8.