New levodopa sustained-release floating minitablets coated with insoluble acrylic polymer

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 68, Issue 2, 2008, Pages 310-318

  Goole, J ^a   Deleuze, Ph ^a   Vanderbist, F ^b   Amighi, K ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b Laboratoires SMB SA   (Belgium)

Author keywords

Coating; Eudragit RL30D; Floating; Levodopa; Minitablets; Multiple unit system; Sustained release

Indexed keywords

LEVODOPA; POLYACRYLIC ACID;

ARTICLE; COATED PARTICLE; COMPRESSION; DRUG COATING; DRUG GRANULE; DRUG STABILITY; EXCIPIENT COMPATIBILITY; SUSTAINED DRUG RELEASE; TABLET FORMULATION;

ACRYLIC RESINS; DELAYED-ACTION PREPARATIONS; LEVODOPA; SOLUBILITY; TABLETS;

EID: 37849023418     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2007.06.017     Document Type: Article

References (23)

1. Ianuccelli V., Coppi G., Bernabei M.T., and Cameroni R. Air compartment multiple-unit system for prolonged gastric residence. Part I. Formulation study. Int. J. Pharm. 174 (1998) 47-54
2. Clarke's Isolation and Identification of Drugs in Pharmaceutics, Body Fluids, and Post-Mortem Material, second ed., The Pharmaceutical Press, London, 1986.
3. Stocchi F., Quinn N.P., Barbato L., Patsalos P.N., O'Connel M.T., Ruggieri S., and Mardsen C.D. Comparison between a fast and a slow release preparation of levodopa and combination of the two: a clinical and pharmacokinetic study. Clin. Neuropharmacol. 17 (1994) 38-44
4. Moës A.J. Gastroretentive dosage forms. Crit. Rev. Ther. Drug Carrier Syst. 10 (1993) 143-195
5. N. Talwar, H. Sen, J.N. Staniforth, Orally administered controlled drug delivery system providing temporal and special control, US patent 6,261,601 (2001).
6. Klausner E.A., Lavy E., Friedman M., and Hoffman A. Expandable gastroretentive dosage forms. J. Control. Release 90 (2003) 143-162
7. Sato Y., Kawashima Y., Takeuchi H., and Yamamoto H. In vitro and in vivo evaluation of riboflavin-containing microballoons for a floating controlled drug delivery system in healthy humans. Int. J. Pharm. 275 (2004) 97-107
8. Hwang S.-J., Park H., and Park K. Gastric retentive drug-delivery systems. Crit. Rev. Ther. Drug Carrier Syst. 15 (1998) 243-284
9. Singh B.N., and Kim K.H. Floating drug delivery systems: an approach to oral controlled drug delivery via gastric retention. J. Control. Release 63 (2000) 235-259
10. Goole J., Vanderbist F., and Amighi K. Development and evaluation of new multiple-unit levodopa sustained-release floating dosage forms. Int. J. Pharm. 334 (2007) 35-41
11. Hamdani J., Moës A.J., and Amighi K. Development and in vitro evaluation of a novel floating multiple unit dosage form obtained by melt pelletization. Int. J. Pharm 322 (2006) 96-103
12. Ichikawa M., Watanabe S., and Miyake Y. A new multiple-unit oral floating dosage system. I. Preparation and in vitro evaluation of floating and sustained-release characteristics. J. Pharm. Sci. 80 (1991) 1062-1066
13. Sungthongjeen S., Paeratakul O., Limmatvapirat S., and Puttipipatkhachorn S. Preparation and in vitro evaluation of a multiple-unit floating drug delivery system based on gas formation technique. Int. J. Pharm 324 (2006) 136-143
14. Streubel A., Siepmann J., and Bodmeier R. Floating matrix tablets based on low density foam powder: effects of formulation and processing parameters on drug release. Eur. J. Pharm. Sci. 18 (2003) 37-45
15. Hamdani J., Moës A.J., and Amighi K. Development and evaluation of prolonged release pellets obtained by the melt pelletization process. Int. J. Pharm. 245 (2002) 167-177
16. Amighi K., and Moës A.J. Evaluation of thermal and film forming properties of acrylic aqueous polymer dispersion blends: application to the formulation of sustained-release film coated theophylline pellets. Drug Dev. Ind. Pharm. 21 (1995) 2355-2369
17. Amighi K., and Moës A.J. Influence of curing conditions on the drug release rate from Eudragit NE30D film coated sustained-release theophylline pellets. S.T.P. Pharma Sci. 7 (1997) 141-147
18. Timmermans J., and Moës A.J. Measuring the resultant-weight of an immersed test material. I. Validation of an apparatus and a method dedicated to pharmaceutical applications. Acta Pharm. Technol. 36 (1990) 171-175
19. Guidance for Industry, Extended Release Oral Dosage Form: Development Evaluation, and Application of In Vitro/In Vivo correlations, September 1997, U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research.
20. 2. Pharm. Res. 15 (1998) 889-896
21. Krögel I., and Bodmeier R. Floating or pulsatile drug delivery systems based on coated effervescent cores. Int. J. Pharm. 187 (1999) 175-184
22. Bodmeier R., and Paeratakul O. Leaching of water-soluble plasticizers from polymeric films prepared from aqueous colloidal polymer dispersions. Drug Dev. Ind. Pharm. 18 (1992) 1865-1882
23. Gutiérrez-Rocca J.C., and McGinity J.W. Influence of water soluble and insoluble plasticizers on the physical and mechanical properties of acrylic resin copolymers. Int. J. Pharm. 103 (1994) 293-301