Local hospital vs. core-laboratory interpretation of the admission electrocardiogram in acute coronary syndromes: Increased mortality in patients with unrecognized ST-elevation myocardial infarction

European Heart Journal

Volumn 29, Issue 1, 2008, Pages 31-37

  Vijayaraghavan, Ram ^a   Yan, Andrew T ^b,c   Tan, Mary ^c   Fitchett, David H ^b,c   Georgescu, Alina A ^c   Hassan, Quamrul ^c   Langer, Anatoly ^b,c   Goodman, Shaun G ^b,c  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

^c CANADIAN HEART RESEARCH CENTRE   (Canada)

Author keywords

Acute coronary syndromes; Electrocardiogram; Prognosis

Indexed keywords

ACETYLSALICYLIC ACID; HEPARIN;

ACUTE CORONARY SYNDROME; ADULT; ARTICLE; CARDIOVASCULAR RISK; CONFIDENCE INTERVAL; CORE LABORATORY; DIABETES MELLITUS; ELECTROCARDIOGRAM; FEMALE; HEART INFARCTION; HOSPITAL; HOSPITAL ADMISSION; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; LABORATORY DIAGNOSIS; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; PROGNOSIS; REPERFUSION; SMOKING; ST SEGMENT ELEVATION;

ACUTE CORONARY SYNDROME; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CANADA; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; LABORATORIES; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; ODDS RATIO; PROGNOSIS;

EID: 37849004582     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehm503     Document Type: Article

References (17)

1. Savonitto S, Ardissino D, Granger CB, Morando G, Prando MD, Mafrici A, Cavallini C, Melandri G, Thompson TD, Vahanian A, Ohman EM, Califf RM, Van de Werf F, Topol EJ for the Global Use of Strategies to Open Coronary Arteries Investigators (GUSTO). Prognostic value of the admission electrocardiogram in acute coronary syndromes. JAMA 1999;281:707-713.
2. Cannon CP, McCabe CH, Stone PH, Rogers WJ, Schactman M, Thompson BW, Pearce DJ, Diver DJ, Kells C, Feldman T, Williams M, Gibson RS, Kronenberg MW, Ganz LI, Anderson HV, Braunwald E. The electrocardiogram predicts one-year outcome of patients with unstable angina and non-Q-wave myocardial infarction: Results of the TIMI III registry ECG ancillary study. J Am Coll Cardiol 1997;30:133-140.
3. Holmvang L, Hasbak P, Clemmensen P, Wagner G, Grande P. Differences between local investigator and core-laboratory interpretation of the admission ECG in patients with unstable angina pectoris or non-Q-wave myocardial infarction (A thrombin inhibition in myocardial ischemia (TRIM) substudy). Am J Cardiol 1998;82:54-60.
4. Goodman SG, Fu Y, Langer A, Barr A, Tan M, Wagner GS, Barbagelata A, Sgarbossa EB, Birnbaum Y, Granger CB, Califf RM, Van de Werf F, Topol EJ, Armstrong PW for the GUSTO-IIb Investigators. The prognostic value of the admission and pre-discharge electrocardiogram in acute coronary syndromes: the GUSTO-IIb ECG Core Laboratory experience. Am Heart J 2006;152:277- 284.
5. Jayes RL Jr, Larsen GC, Beshansky JR, D'Agostino RB, Selker HP. Physician electrocardiogram reading in the emergency department-accuracy and effect on triage decisions: findings from a multicenter study. J Gen Intern Med 1992;7:387-392. Jul-Aug.
6. Brady WJ, Perron A, Ullman E. Errors in emergency physician interpretation of ST-segment elevation in emergency department chest pain patients. Acad Emerg Med 2000;7:1256-1260.
7. Berger A, Meier JM, Stauffer JC, Stauffer JC, Eckert P, Schlaepfer J, Gillis D, Cornuz J, Yersin B, Schaller MD, Kappenberger L, Wasserfallen JBl. ECG interpretation during the acute phase of coronary syndromes: in need of improvement? Swiss Med Wkly 2004;134:695-699.
8. Yan AT, Tan M, Fitchett D, Chow CM, Fowlis RA, McAvinue TG, Roe MT, Peterson ED, Tu JV, Langer A, Goodman SG for the Canadian Acute Coronary Syndromes Registry Investigators. One-year outcome of patients after acute coronary syndromes (from the Canadian Acute Coronary Syndromes Registry). Am J Cardiol 2004;94:25-29.
9. Fu Y, Goodman S, Chang W-C, Van de Werf F, Granger CB, Armstrong PW for the ASSENT-2 Investigators. Time to treatment influences the impact of ST-segment resolution on one-year prognosis. Circulation 2001;104:2653-2659.
10. Goodman SG, Barr A, Langer A, Wagner GS, Fitchett D, Armstrong PW, Naylor CD. Development and prognosis of non-Q-wave myocardial infarction in the thrombolytic era. Am Heart J 2002;144:243-250.
11. Fox KAA, Goldberg RJ, Pieper K, Cannon CP, Van de Werf F, Goodman SG, Dabbous O, Granger CB for the Global Registry of Acute Coronary Events Registry Investigators (GRACE). Predictors of in-hospital mortality in the Global Registry of Acute Coronary Events. Arch Intern Med 2003;163:2345- 2353.
12. Yan AT, Jong P, Yan RT, Tan M, Fitchett D, Chow CM, Roe MT, Pieper KS, Langer A, Goodman SG for the Canadian Acute Coronary Syndromes (ACS) Registry Investigators. Clinical trialderived risk model may not generalize to real-world patients with acute coronary syndrome. Am Heart J 2004;148:1020- 1027.
13. Fibrinolytic Therapy Trialists' (FTT) Collaborative Group. Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients. Lancet 1994;343:311-322.
14. Baigent C, Collins R, Appleby P, Parish S, Sleight P, Peto R for the ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. ISIS-2: 10-year survival among patients with suspected acute myocardial infarction in randomised comparison of intravenous streptokinase, oral aspirin, both, or neither. BMJ 1998;316:1337-1343.
15. Franzosi MG, Santoro E, De Vita C, Geraci E, Lotto A, Maggioni AP, Mauri F, Rovelli F, Santoro L, Tavazzi L, Tognoni G for the GISSI Investigators. Ten-year follow-up of the first megatrial testing thrombolytic therapy in patients with acute myocardial infarction: results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto-1 study. Circulation 1998;98:2659-2665.
16. Eagle KA, Goodman SG, Avezum A, Budaj A, Sullivan CM, Lopez-Sendon J for the GRACE investigators. Practice variation and missed opportunities for reperfusion in ST-segment-elevation myocardial infarction: findings from the Global Registry of Acute Coronary Events (GRACE). Lancet 2002;359:373-377.
17. Rogers WJ, Canto JG, Lambrew CT, Tiefenbrunn AJ, Kinkaid B, Shoultz DA, Frederick PD, Every N. Temporal trends in the treatment of over 1.5 million patients with myocardial infarction in the U.S. from 1990 through 1999. J Am Coll Cardiol 2000;36:2056-2063.