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Volumn 20, Issue 4, 2007, Pages 673-684

An optimised data analysis for the Balb/c 3T3 cell transformation assay and its application to metal compounds

Author keywords

Alternative methods; Balb c3T3; Cell transformation assay; Fisher's exact test; Metal compounds; t test

Indexed keywords

ARSENIC ACID DERIVATIVE; CADMIUM CHLORIDE; CARCINOGEN; HEXACHLOROPLATINATE AMMONIUM; METAL DERIVATIVE; METHYLMERCURY; PLATINUM DERIVATIVE; SILVER NITRATE; SODIUM POLYMETAARSENITE; UNCLASSIFIED DRUG;

EID: 37749046946     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463200702000403     Document Type: Article
Times cited : (7)

References (46)
  • 1
    • 0034005037 scopus 로고    scopus 로고
    • Non-Hodgkin's lymphoma and occupational exposure to chemicals in Canada. Canadian Cancer Registries Epidemiology Research Group
    • Mao Y., J. Hu, A.M. Ugnat and K. White. 2000. Non-Hodgkin's lymphoma and occupational exposure to chemicals in Canada. Canadian Cancer Registries Epidemiology Research Group. Ann. Oncol. 11:69.
    • (2000) Ann. Oncol , vol.11 , pp. 69
    • Mao, Y.1    Hu, J.2    Ugnat, A.M.3    White, K.4
  • 2
    • 1642485033 scopus 로고    scopus 로고
    • Occupation and the risk of lung cancer by histologic types and morphologic distribution: A case control study in Turkey
    • Elci O.C., M. Akpinar-Elci, M. Alavanja and M. Dosemeci. 2003. Occupation and the risk of lung cancer by histologic types and morphologic distribution: a case control study in Turkey. Monaldi Arch. Chest. Dis. 59:183.
    • (2003) Monaldi Arch. Chest. Dis , vol.59 , pp. 183
    • Elci, O.C.1    Akpinar-Elci, M.2    Alavanja, M.3    Dosemeci, M.4
  • 4
    • 20344370996 scopus 로고    scopus 로고
    • Factor analysis of pesticide use patterns among pesticide applicators in the Agricultural Health Study
    • Samanic C., J.A Hoppin, J.H. Lubin, A. Blair and M.C. Alavanja. 2005. Factor analysis of pesticide use patterns among pesticide applicators in the Agricultural Health Study. J. Expo. Anal. Environ. Epidemiol. 15:225.
    • (2005) J. Expo. Anal. Environ. Epidemiol , vol.15 , pp. 225
    • Samanic, C.1    Hoppin, J.A.2    Lubin, J.H.3    Blair, A.4    Alavanja, M.C.5
  • 5
    • 0032242572 scopus 로고    scopus 로고
    • Epidemiological evidence of the effects of behaviour and the environment on the risk of human cancer
    • Doll R. 1998. Epidemiological evidence of the effects of behaviour and the environment on the risk of human cancer. Recent Results Cancer Res. 154: 3.
    • (1998) Recent Results Cancer Res , vol.154 , pp. 3
    • Doll, R.1
  • 6
    • 0015861335 scopus 로고
    • A quantitative system for assay of malignant transformation by carcinogens using a clone derived from Balb-3T3
    • Kakunaga T. 1973. A quantitative system for assay of malignant transformation by carcinogens using a clone derived from Balb-3T3. Int. J. Cancer. 12:463.
    • (1973) Int. J. Cancer , vol.12 , pp. 463
    • Kakunaga, T.1
  • 7
    • 0015732254 scopus 로고
    • Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division
    • Reznikoff C.A., J.S. Bertram, D.W. Brankow and C. Heidelberger. 1973. Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division. Cancer Res. 33:3239.
    • (1973) Cancer Res , vol.33 , pp. 3239
    • Reznikoff, C.A.1    Bertram, J.S.2    Brankow, D.W.3    Heidelberger, C.4
  • 8
    • 0015752438 scopus 로고
    • Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division
    • Reznikoff C.A., D.W. Brankow and C. Heidelberger. 1973. Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division. Cancer Res. 33:3231.
    • (1973) Cancer Res , vol.33 , pp. 3231
    • Reznikoff, C.A.1    Brankow, D.W.2    Heidelberger, C.3
  • 9
    • 84910450150 scopus 로고
    • Factors influencing neoplastic transformation by chemical carcinogens in Balb/c-3T3 cells
    • G.M. Williams, R. Kroes, H.W. Waaijers, K.W. Van de Poll, eds. Elsevier/North Holland Biomedical Press, Amsterdam, New York, Oxford, p
    • Sivak A. and A.S. Tu. 1980. Factors influencing neoplastic transformation by chemical carcinogens in Balb/c-3T3 cells. In The predictive value of short-term screening tests in carcinogenicity evaluation, G.M. Williams, R. Kroes, H.W. Waaijers, K.W. Van de Poll, eds. Elsevier/North Holland Biomedical Press, Amsterdam, New York, Oxford, p. 177.
    • (1980) The predictive value of short-term screening tests in carcinogenicity evaluation , pp. 177
    • Sivak, A.1    Tu, A.S.2
  • 10
    • 85036989688 scopus 로고    scopus 로고
    • Sivak A., M.C. Charest, L. Rudenko, D.M. Silveira, I. Simons and A.M. Wood. 1980. Balb/c-3T3 cells as target cells for chemically induced neoplastic transformation. In Advances in modern environmental toxicology, mammalian cell transformation by chemical carcinogens, I. N.J. Mishra, N. Dunkel, V. Mehlman, eds. Senate Press, Princeton Junction, p. 133.
    • Sivak A., M.C. Charest, L. Rudenko, D.M. Silveira, I. Simons and A.M. Wood. 1980. Balb/c-3T3 cells as target cells for chemically induced neoplastic transformation. In Advances in modern environmental toxicology, mammalian cell transformation by chemical carcinogens, Vol I. N.J. Mishra, N. Dunkel, V. Mehlman, eds. Senate Press, Princeton Junction, p. 133.
  • 12
    • 84969069250 scopus 로고
    • Cellular and molecular mechanisms of cell transformation and standardization of transformed assays of established cell lines for the prediction of carcinogenic chemicals: Overview and recommended protocols
    • IARC/NCI/EPA Working Group
    • IARC/NCI/EPA Working Group. 1985. Cellular and molecular mechanisms of cell transformation and standardization of transformed assays of established cell lines for the prediction of carcinogenic chemicals: Overview and recommended protocols. Cancer Res. 45:2395.
    • (1985) Cancer Res , vol.45 , pp. 2395
  • 13
    • 0025978025 scopus 로고
    • Recommended protocols based on a survey of current practice in genotoxicity testing laboratories: III. Cell transformation in C3H/10T1/2 mouse embryo cell, Balb/c3T3 mouse fibroblast and Syrian hamster embryo cell cultures
    • Dunkel V.C., C. Rogers, S.H. Swierenga, R.L. Brillinger, J. P. Gilman and E.R. Nestmann. 1991. Recommended protocols based on a survey of current practice in genotoxicity testing laboratories: III. Cell transformation in C3H/10T1/2 mouse embryo cell, Balb/c3T3 mouse fibroblast and Syrian hamster embryo cell cultures. Mutat. Res. 246:285.
    • (1991) Mutat. Res , vol.246 , pp. 285
    • Dunkel, V.C.1    Rogers, C.2    Swierenga, S.H.3    Brillinger, R.L.4    Gilman, J.P.5    Nestmann, E.R.6
  • 14
    • 85036997651 scopus 로고    scopus 로고
    • Environmental Protection Agency. 1996. Morphologic Transformation of Cells in Culture. Health Effects Test Guidelines OPPTS 870.8800, United States Environmental Protection Agency, Office for Prevention, Pesticides and Toxic Substances, EPA712-C-96-260, June 1996.
    • Environmental Protection Agency. 1996. Morphologic Transformation of Cells in Culture. Health Effects Test Guidelines OPPTS 870.8800, United States Environmental Protection Agency, Office for Prevention, Pesticides and Toxic Substances, EPA712-C-96-260, June 1996.
  • 16
    • 85036987680 scopus 로고    scopus 로고
    • EEC. 1981. Commission Decision of 11 May 1981 laying down the criteria in accordance with which information relating to the inventory of chemical substances is supplied by the Member States to the Commission 81/437/EEC, Official Journal of the European Communities, No L 167/31.
    • EEC. 1981. Commission Decision of 11 May 1981 laying down the criteria in accordance with which information relating to the inventory of chemical substances is supplied by the Member States to the Commission 81/437/EEC, Official Journal of the European Communities, No L 167/31.
  • 17
    • 0015458712 scopus 로고
    • Quantisation of chemically induced neoplastic transformation of BALB/3T3 cloned cell lines
    • Di Paolo J.A., K. Takano and N.C. Popescu. 1972. Quantisation of chemically induced neoplastic transformation of BALB/3T3 cloned cell lines. Cancer Res. 32:2686.
    • (1972) Cancer Res , vol.32 , pp. 2686
    • Di Paolo, J.A.1    Takano, K.2    Popescu, N.C.3
  • 19
    • 0000739062 scopus 로고
    • The relevance of sister-chromatid exchange to the induction of neoplastic cell transformation
    • ed. A.R. Liss, New York, p
    • Popescu N. and J. Dipaolo. 1982. The relevance of sister-chromatid exchange to the induction of neoplastic cell transformation. In Sister Chromatid Exchange, ed. A.R. Liss, New York, p. 425.
    • (1982) Sister Chromatid Exchange , pp. 425
    • Popescu, N.1    Dipaolo, J.2
  • 20
    • 0023237768 scopus 로고
    • Cellular uptake and metabolic reduction of pentavalent to trivalent arsenic as determinants of cytotoxicity and morphological transformation
    • Bertolero F., G. Pozzi, E. Sabbioni and U. Saffiotti. 1987. Cellular uptake and metabolic reduction of pentavalent to trivalent arsenic as determinants of cytotoxicity and morphological transformation. Carcinogenesis 8:803.
    • (1987) Carcinogenesis , vol.8 , pp. 803
    • Bertolero, F.1    Pozzi, G.2    Sabbioni, E.3    Saffiotti, U.4
  • 21
    • 0024554118 scopus 로고
    • An interlaboratory comparison of enhanced morphological transformation of Syrian hamster embryo cells cultured under conditions of reduced bicarbonate concentration and pH
    • LeBoeuf R.A., G.A. Kerckaert, J.A. Poiley and R. Raineri. 1989. An interlaboratory comparison of enhanced morphological transformation of Syrian hamster embryo cells cultured under conditions of reduced bicarbonate concentration and pH. Mutat. Res. 222:205.
    • (1989) Mutat. Res , vol.222 , pp. 205
    • LeBoeuf, R.A.1    Kerckaert, G.A.2    Poiley, J.A.3    Raineri, R.4
  • 22
    • 0026090587 scopus 로고
    • Cellular retention, cytotoxicity and morphological transformation by vanadium(IV) and vanadium(V) in BALB/3T3 cell lines
    • Sabbioni E., G. Pozzi, A. Pintar, L. Casella and S. Garattini. 1991. Cellular retention, cytotoxicity and morphological transformation by vanadium(IV) and vanadium(V) in BALB/3T3 cell lines. Carcinogenesis 12:47.
    • (1991) Carcinogenesis , vol.12 , pp. 47
    • Sabbioni, E.1    Pozzi, G.2    Pintar, A.3    Casella, L.4    Garattini, S.5
  • 23
    • 0027724847 scopus 로고
    • The intensity of vanadium(V)-induced cytotoxicity and morphological transformation in BALB/3T3 cells is dependent on glutathione-mediated bioreduction to vanadium(IV)
    • Sabbioni E., G. Pozzi, S. Devos, A. Pintar, L. Casella and M. Fischbach. 1993. The intensity of vanadium(V)-induced cytotoxicity and morphological transformation in BALB/3T3 cells is dependent on glutathione-mediated bioreduction to vanadium(IV). Carcinogenesis 14:2565.
    • (1993) Carcinogenesis , vol.14 , pp. 2565
    • Sabbioni, E.1    Pozzi, G.2    Devos, S.3    Pintar, A.4    Casella, L.5    Fischbach, M.6
  • 24
    • 0025875812 scopus 로고
    • Cellular retention, toxicity and carcinogenic potential of seafood arsenic. I. Lack of cytotoxicity and transforming activity of arsenobetaine in the BALB/3T3 cell line
    • Sabbioni E, M. Fischbach, G. Pozzi, R. Pietra, M. Gallorini and J.L. Piette. 1991. Cellular retention, toxicity and carcinogenic potential of seafood arsenic. I. Lack of cytotoxicity and transforming activity of arsenobetaine in the BALB/3T3 cell line. Carcinogenesis 12:1287.
    • (1991) Carcinogenesis , vol.12 , pp. 1287
    • Sabbioni, E.1    Fischbach, M.2    Pozzi, G.3    Pietra, R.4    Gallorini, M.5    Piette, J.L.6
  • 25
    • 0036098584 scopus 로고    scopus 로고
    • In vitro setting of dose-effect relationships of 32 metal compounds in the Balb/3T3 cell line as a basis for predicting their carcinogenic potential
    • Mazzotti F., E. Sabbioni, J. Ponti, M. Ghiani, S. Fortaner and G.L. Rossi. 2002. In vitro setting of dose-effect relationships of 32 metal compounds in the Balb/3T3 cell line as a basis for predicting their carcinogenic potential. ATLA 30:209.
    • (2002) ATLA , vol.30 , pp. 209
    • Mazzotti, F.1    Sabbioni, E.2    Ponti, J.3    Ghiani, M.4    Fortaner, S.5    Rossi, G.L.6
  • 26
    • 0021708059 scopus 로고
    • Studies on chemically induced neoplastic transformation and mutation in the Balb/3T3 Cl A31-1-1 cell line in relation to the quantitative evaluation of carcinogens
    • Saffiotti U., F. Bertolero, M. Bignami, F. Cortesi, C. Ficarella and M.E. Kaighn. 1984. Studies on chemically induced neoplastic transformation and mutation in the Balb/3T3 Cl A31-1-1 cell line in relation to the quantitative evaluation of carcinogens. Toxicol. Pathol. 12:383.
    • (1984) Toxicol. Pathol , vol.12 , pp. 383
    • Saffiotti, U.1    Bertolero, F.2    Bignami, M.3    Cortesi, F.4    Ficarella, C.5    Kaighn, M.E.6
  • 28
    • 84972545970 scopus 로고
    • A Survey of Exact Inference for Contingency Tables
    • Agresti A. 1992. A Survey of Exact Inference for Contingency Tables. Statistical Science 7:131.
    • (1992) Statistical Science , vol.7 , pp. 131
    • Agresti, A.1
  • 29
    • 0027521723 scopus 로고
    • Transformation of BALB/c-3T3 cells: IV. Rank-ordered potency of 24 chemical responses detected in a sensitive new assay procedure
    • Matthews E.J., J.W. Spalding and R.W. Tennant. 1993. Transformation of BALB/c-3T3 cells: IV. Rank-ordered potency of 24 chemical responses detected in a sensitive new assay procedure. Environ. Health Perspect. 101:319.
    • (1993) Environ. Health Perspect , vol.101 , pp. 319
    • Matthews, E.J.1    Spalding, J.W.2    Tennant, R.W.3
  • 30
    • 85036975561 scopus 로고    scopus 로고
    • NTP (National Toxicology Program). 1993. NTP technical report on the toxicology and carcinogenesis of mercuric chloride (CAS No. 7487-94-7) in F344 rats and B6C3F1 mice (gavage studies). NTP TR 408. National Toxicology Program, U.S. Dept. Health Human serv., Public Health Service, National Institutes of Health, Research Triangle Park, North Carolina.
    • NTP (National Toxicology Program). 1993. NTP technical report on the toxicology and carcinogenesis of mercuric chloride (CAS No. 7487-94-7) in F344 rats and B6C3F1 mice (gavage studies). NTP TR 408. National Toxicology Program, U.S. Dept. Health Human serv., Public Health Service, National Institutes of Health, Research Triangle Park, North Carolina.
  • 31
    • 0022671766 scopus 로고
    • Further carcinogenicity study on methylmercury chloride in ICR mice
    • Hirano M., K. Mitsumori, K. Maita and Y. Shirasu. 1986. Further carcinogenicity study on methylmercury chloride in ICR mice. Jpn. J. Vet. Sci. 48:127.
    • (1986) Jpn. J. Vet. Sci , vol.48 , pp. 127
    • Hirano, M.1    Mitsumori, K.2    Maita, K.3    Shirasu, Y.4
  • 32
    • 0020997724 scopus 로고
    • Chronic toxicity of methylmercury chloride in rats: Clinical study and chemical analysis
    • Mitsumori K., K. Takahashi, O. Matano, S. Goto and Y. Shirasu. 1983. Chronic toxicity of methylmercury chloride in rats: clinical study and chemical analysis. Japan. J. Vet. Sci. 45:747.
    • (1983) Japan. J. Vet. Sci , vol.45 , pp. 747
    • Mitsumori, K.1    Takahashi, K.2    Matano, O.3    Goto, S.4    Shirasu, Y.5
  • 33
    • 0021470895 scopus 로고
    • Chronic toxicity of methylmercury chloride in rats: Pathological study
    • Mitsumori K., K. Maiata and Y. Shirasu. 1984. Chronic toxicity of methylmercury chloride in rats: pathological study. Japan. J. Vet. Sci. 46:549.
    • (1984) Japan. J. Vet. Sci , vol.46 , pp. 549
    • Mitsumori, K.1    Maiata, K.2    Shirasu, Y.3
  • 34
  • 35
    • 0027422242 scopus 로고
    • Transformation of BALB/c-3T3 Cells: II. Investigation of Experimental Parameters That Influence Detection of Benzo(a)pyrene-Induced Transformation
    • Matthews E.J. 1993. Transformation of BALB/c-3T3 Cells: II. Investigation of Experimental Parameters That Influence Detection of Benzo(a)pyrene-Induced Transformation. Environ. Health Perspectives, 101:293.
    • (1993) Environ. Health Perspectives , vol.101 , pp. 293
    • Matthews, E.J.1
  • 36
    • 0013808158 scopus 로고
    • In vitro transformation of normal cells to tumor cells by carcinogenic hydrocarbons
    • Berwald Y. and L. Sachs. 1965. In vitro transformation of normal cells to tumor cells by carcinogenic hydrocarbons. J. Natl. Cancer Inst. 35:641.
    • (1965) J. Natl. Cancer Inst , vol.35 , pp. 641
    • Berwald, Y.1    Sachs, L.2
  • 37
    • 0035325211 scopus 로고    scopus 로고
    • Data quality in predictive toxicology: Reproducibility of rodent carcinogenicity experiments
    • Gottmann E., S. Kramer, B. Pfahringer and C. Helma. 2001. Data quality in predictive toxicology: reproducibility of rodent carcinogenicity experiments. Environ. Health Perspectives. 109:509.
    • (2001) Environ. Health Perspectives , vol.109 , pp. 509
    • Gottmann, E.1    Kramer, S.2    Pfahringer, B.3    Helma, C.4
  • 39
    • 0022446197 scopus 로고
    • Relative potency of chemical carcinogens in rodents
    • Gaylor D.W. and J.J. Chen. 1986. Relative potency of chemical carcinogens in rodents. Risk Anal. 6:283.
    • (1986) Risk Anal , vol.6 , pp. 283
    • Gaylor, D.W.1    Chen, J.J.2
  • 40
    • 0027493090 scopus 로고
    • Transformation of BALB/c-3T3 cells: I. Investigation of experimental parameters that influence detection of spontaneous transformation
    • Matthews E.J. 1993. Transformation of BALB/c-3T3 cells: I. Investigation of experimental parameters that influence detection of spontaneous transformation. Environ. Health Perspect. 101:277.
    • (1993) Environ. Health Perspect , vol.101 , pp. 277
    • Matthews, E.J.1
  • 41
    • 85036996737 scopus 로고    scopus 로고
    • Anon. 1996. Morphologic Transformation of Cells in Culture. Health Effects Test Guidelines. OPPTS 870.8800. United States Environmental Protection Agency, Prevention, Pesticides and Toxic Substances (7101), EPA712-0-96-260, June 1996.
    • Anon. 1996. Morphologic Transformation of Cells in Culture. Health Effects Test Guidelines. OPPTS 870.8800. United States Environmental Protection Agency, Prevention, Pesticides and Toxic Substances (7101), EPA712-0-96-260, June 1996.
  • 42
    • 0020448628 scopus 로고    scopus 로고
    • Whorton E.B., J.B. Ward and D.L. Morris Jr. 1982. Experimental design and statistical analysis considerations for in vitro mammalian cell transformation assays with Balb/3T3 cells. Environ. Mutagen. 4:595.
    • Whorton E.B., J.B. Ward and D.L. Morris Jr. 1982. Experimental design and statistical analysis considerations for in vitro mammalian cell transformation assays with Balb/3T3 cells. Environ. Mutagen. 4:595.
  • 43
    • 3042536299 scopus 로고    scopus 로고
    • Three-step method of data analysis, incorporating multiple contrast method to detect carcinogenic substances in cell transformation assay
    • Aug. 10-15, New Orleans, LA USA, Poster abstract E21
    • Nishiyama H., T. Tsuchiya, I. Yoshimura and M. Umeda. 2002. Three-step method of data analysis, incorporating multiple contrast method to detect carcinogenic substances in cell transformation assay. Fourth World Congress on Alternatives and Animal Use in the Life Sciences, Aug. 10-15, New Orleans, LA (USA), Poster abstract E21.
    • (2002) Fourth World Congress on Alternatives and Animal Use in the Life Sciences
    • Nishiyama, H.1    Tsuchiya, T.2    Yoshimura, I.3    Umeda, M.4
  • 45
    • 34250101817 scopus 로고
    • Assessment of chemical carcinogen-induced transforming activity using BALB/C-3T3 cells
    • Matthews E.J. 1986. Assessment of chemical carcinogen-induced transforming activity using BALB/C-3T3 cells. J. Tiss. Cult. Meth. 10:157.
    • (1986) J. Tiss. Cult. Meth , vol.10 , pp. 157
    • Matthews, E.J.1
  • 46
    • 0018740960 scopus 로고
    • Enhancement of viral transformation for evaluation of the carcinogenic or mutagenic potential of inorganic metal salts
    • Casto B.C., J. Meyers and J.A. Dipaolo. 1979. Enhancement of viral transformation for evaluation of the carcinogenic or mutagenic potential of inorganic metal salts. Cancer Res. 39:193.
    • (1979) Cancer Res , vol.39 , pp. 193
    • Casto, B.C.1    Meyers, J.2    Dipaolo, J.A.3


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