Does trimetazidine prevent myocardial injury after percutaneous coronary intervention? Commentary

Nature Clinical Practice Cardiovascular Medicine

Volumn 5, Issue 1, 2008, Pages 16-17

  Marzilli, Mario ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; HEPARIN; PLACEBO; TRIMETAZIDINE; TROPONIN I;

ANTICOAGULANT THERAPY; AREA UNDER THE CURVE; ATHEROSCLEROTIC PLAQUE; CARDIOPULMONARY BYPASS; CLINICAL TRIAL; CORONARY ARTERY BYPASS GRAFT; CORONARY STENT; DRUG MECHANISM; ELECTROCARDIOGRAPHY; FREQUENCY ANALYSIS; HEART MUSCLE INJURY; HEART REINFARCTION; HUMAN; LOADING DRUG DOSE; MAINTENANCE THERAPY; MORTALITY; NONHUMAN; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN SECRETION; RECEIVER OPERATING CHARACTERISTIC; REPERFUSION INJURY; SHORT SURVEY; ST SEGMENT ELEVATION; STABLE ANGINA PECTORIS; T WAVE; UNSPECIFIED SIDE EFFECT;

EID: 37749031078     PISSN: 17434297     EISSN: 17434300     Source Type: Journal    
DOI: 10.1038/ncpcardio1013     Document Type: Short Survey

References (5)

1. Simoons ML et al. (1999) Minimal myocardial damage during coronary intervention is associated with impaired outcome. Eur Heart J 2 1112-1119
2. Stanley WC and Marzilli M (2003) Metabolic therapy in the treatment of ischemic heart disease: The pharmacology of trimetazidine. Fundam Clin Pharmacol 17:133-145
3. Kober G et al. (1993) Myocardial cytoprotection during percutaneous transluminal coronary angioplasty. Eur Heart J 14 (Suppl G): S6-S11
4. Polonski I et al. (2002) Trimetazidine limits the effects of myocardial ischemia during percutaneous coronary angioplasty. Curr Med Res Opin 18: 389-396
5. Tünerir B et al. (1999) Measurement of troponin T to detect cardioprotective effect of trimetazidine during coronary artery bypass grafting. Ann Thorac Surg 68: 2173-2176