메뉴 건너뛰기




Volumn 23, Issue 12, 2007, Pages 3189-3198

Phosphodiesterase type 5 inhibitor therapy: Identifying and exploring what attributes matter more to clinicians and patients in the management of erectile dysfunction

Author keywords

Comorbidities; Erectile dysfunction; Erection; First dose success; PDE5 inhibitors; Vardenafil

Indexed keywords

PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL; TADALAFIL; VARDENAFIL;

EID: 37749013595     PISSN: 03007995     EISSN: None     Source Type: Journal    
DOI: 10.1185/030079907X242656     Document Type: Review
Times cited : (8)

References (64)
  • 1
    • 0002486987 scopus 로고    scopus 로고
    • Recommendations of the first international consultation on erectile dysfunction
    • Jardin A, Wagner G, Khoury S, Giuliano F, eds, Plymouth, UK: Health Publications
    • Jardin A, Wagner G, Khoury S. Recommendations of the first international consultation on erectile dysfunction. In: Jardin A, Wagner G, Khoury S, Giuliano F, eds. Erectile Dysfunction. Plymouth, UK: Health Publications, 2000
    • (2000) Erectile Dysfunction
    • Jardin, A.1    Wagner, G.2    Khoury, S.3
  • 2
    • 31344451109 scopus 로고    scopus 로고
    • Predictors and prevalence of erectile dysfunction in a racially diverse population
    • Saigal CS, Wessells H, Pace J, et al. Predictors and prevalence of erectile dysfunction in a racially diverse population. Arch Intern Med 2006;166:207-12
    • (2006) Arch Intern Med , vol.166 , pp. 207-212
    • Saigal, C.S.1    Wessells, H.2    Pace, J.3
  • 3
    • 0028860594 scopus 로고
    • The epidemiology of erectile dysfunction
    • Benet AE, Melman A. The epidemiology of erectile dysfunction. Urol Clin North Am 1995;22:699-709
    • (1995) Urol Clin North Am , vol.22 , pp. 699-709
    • Benet, A.E.1    Melman, A.2
  • 4
    • 0028036149 scopus 로고
    • Impotence and its medical and psychosocial correlates: Results of the Massachusetts Male Aging Study
    • Feldman HA, Goldstein I, Hatzichristou DG, et al. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol 1994;151:54-61
    • (1994) J Urol , vol.151 , pp. 54-61
    • Feldman, H.A.1    Goldstein, I.2    Hatzichristou, D.G.3
  • 5
    • 0032810944 scopus 로고    scopus 로고
    • The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences
    • Ayta IA, McKinlay JB, Krane RJ. The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences. BJU Int 1999;84:50-6
    • (1999) BJU Int , vol.84 , pp. 50-56
    • Ayta, I.A.1    McKinlay, J.B.2    Krane, R.J.3
  • 6
    • 0023927382 scopus 로고
    • Impotence and aging: Clinical and hormonal factors
    • Kaiser FE, Viosca SP, Morley JE, et al. Impotence and aging: clinical and hormonal factors. J Am Geriatr Soc 1988;36: 511-19
    • (1988) J Am Geriatr Soc , vol.36 , pp. 511-519
    • Kaiser, F.E.1    Viosca, S.P.2    Morley, J.E.3
  • 7
    • 0023252043 scopus 로고
    • Erectile dysfunction in men with diabetes mellitus
    • Maatman TJ, Montague DK, Martin LM. Erectile dysfunction in men with diabetes mellitus. Urology 1987;29:589-92
    • (1987) Urology , vol.29 , pp. 589-592
    • Maatman, T.J.1    Montague, D.K.2    Martin, L.M.3
  • 8
    • 2542438558 scopus 로고    scopus 로고
    • The multinational Men's Attitudes to Life Events and Sexuality (MALES) study: I. Prevalence of erectile dysfunction and related health concerns in the general population
    • Rosen RC, Fisher WA, Eardley I, et al. The multinational Men's Attitudes to Life Events and Sexuality (MALES) study: I. Prevalence of erectile dysfunction and related health concerns in the general population. Curr Med Res Opin 2004;20:607-17
    • (2004) Curr Med Res Opin , vol.20 , pp. 607-617
    • Rosen, R.C.1    Fisher, W.A.2    Eardley, I.3
  • 9
    • 84942949401 scopus 로고
    • Impotence. NIH Consensus Development Panel on Impotence. JAMA
    • National Institutes of Health Consensus Conference
    • National Institutes of Health Consensus Conference. Impotence. NIH Consensus Development Panel on Impotence. JAMA 1993;270:83-90
    • (1993) , vol.270 , pp. 83-90
  • 10
    • 34250654845 scopus 로고    scopus 로고
    • American Urological Association, American Urological Association (AUA) Education and Research, Inc [online, Available from, Last accessed 07 August
    • American Urological Association 2005. Management of erectile dysfunction: American Urological Association (AUA) Education and Research, Inc [online]. Available from http://www.auanet. org/ [Last accessed 07 August 2007]
    • (2005) Management of erectile dysfunction
  • 11
    • 0142104191 scopus 로고    scopus 로고
    • Erectile dysfunction and vascular disease. What is the connection?
    • Kolodny L. Erectile dysfunction and vascular disease. What is the connection? Postgrad Med 2003;114:30-4
    • (2003) Postgrad Med , vol.114 , pp. 30-34
    • Kolodny, L.1
  • 12
    • 22144467731 scopus 로고    scopus 로고
    • Kostis JB, Jackson G, Rosen R, et al. Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference). Am J Cardiol 2005;96:313-21
    • Kostis JB, Jackson G, Rosen R, et al. Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference). Am J Cardiol 2005;96:313-21
  • 13
    • 33645744784 scopus 로고    scopus 로고
    • The second Princeton consensus on sexual dysfunction and cardiac risk: New guidelines for sexual medicine
    • Jackson G, Rosen RC, Kloner RA, Kostis JB. The second Princeton consensus on sexual dysfunction and cardiac risk: new guidelines for sexual medicine. J Sex Med 2006;3:28-36
    • (2006) J Sex Med , vol.3 , pp. 28-36
    • Jackson, G.1    Rosen, R.C.2    Kloner, R.A.3    Kostis, J.B.4
  • 14
    • 0034840292 scopus 로고    scopus 로고
    • Erectile and endothelial dysfunction in type II diabetes: A possible link
    • De Angelis L, Marfella MA, Siniscalchi M, et al. Erectile and endothelial dysfunction in type II diabetes: a possible link. Diabetologia 2001;44:1155-60
    • (2001) Diabetologia , vol.44 , pp. 1155-1160
    • De Angelis, L.1    Marfella, M.A.2    Siniscalchi, M.3
  • 15
    • 18744404256 scopus 로고    scopus 로고
    • Circulating endothelial progenitor cells in subjects with erectile dysfunction
    • Foresta C, Caretta N, Lana A, et al. Circulating endothelial progenitor cells in subjects with erectile dysfunction. Int J Impot Res 2005;17:288-90
    • (2005) Int J Impot Res , vol.17 , pp. 288-290
    • Foresta, C.1    Caretta, N.2    Lana, A.3
  • 16
    • 0035723771 scopus 로고    scopus 로고
    • Vascular risk factors and erectile dysfunction
    • Sullivan ME, Keoghane SR, Miller MA. Vascular risk factors and erectile dysfunction. BJU Int 2001;87:838-45
    • (2001) BJU Int , vol.87 , pp. 838-845
    • Sullivan, M.E.1    Keoghane, S.R.2    Miller, M.A.3
  • 17
    • 29144533834 scopus 로고    scopus 로고
    • Erectile dysfunction and subsequent cardiovascular disease
    • Thompson IM, Tangen CM, Goodman PJ, et al. Erectile dysfunction and subsequent cardiovascular disease. JAMA 2005;294:2996-3002
    • (2005) JAMA , vol.294 , pp. 2996-3002
    • Thompson, I.M.1    Tangen, C.M.2    Goodman, P.J.3
  • 18
    • 0001680458 scopus 로고    scopus 로고
    • The penile stress test: A window to the hearts of man?
    • Abstract 3751
    • Pritzker MR. The penile stress test: a window to the hearts of man? Circulation 1999;111:3711 [Abstract 3751]
    • (1999) Circulation , vol.111 , pp. 3711
    • Pritzker, M.R.1
  • 19
    • 0000694138 scopus 로고    scopus 로고
    • An analysis of vasculogenic erectile dysfunction as a potential predictor of occult cardiac disease
    • Abstract 118
    • Anderson M, Nicholson B, Louie E, Mulhall JP. An analysis of vasculogenic erectile dysfunction as a potential predictor of occult cardiac disease. J Urol 1998;159:130 [Abstract 118]
    • (1998) J Urol , vol.159 , pp. 130
    • Anderson, M.1    Nicholson, B.2    Louie, E.3    Mulhall, J.P.4
  • 21
    • 33644781490 scopus 로고    scopus 로고
    • Compliance of sildenafil treatment for erectile dysfunction and factors affecting it
    • Jiann BP, Yu CC, Su CC, Tsai JY. Compliance of sildenafil treatment for erectile dysfunction and factors affecting it. Int J Impot Res 2006;18:146-9
    • (2006) Int J Impot Res , vol.18 , pp. 146-149
    • Jiann, B.P.1    Yu, C.C.2    Su, C.C.3    Tsai, J.Y.4
  • 22
    • 3042574999 scopus 로고    scopus 로고
    • Binding of titrated sildenafil, tadalafil, or vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation
    • Blount MA, Beasley A, Zoraghi R, et al. Binding of titrated sildenafil, tadalafil, or vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation. Mol Pharmacol 2004;66:144-52
    • (2004) Mol Pharmacol , vol.66 , pp. 144-152
    • Blount, M.A.1    Beasley, A.2    Zoraghi, R.3
  • 23
    • 0034660235 scopus 로고    scopus 로고
    • Erectile dysfunction
    • Lue TF. Erectile dysfunction. N Engl J Med 2000;342:1802-13
    • (2000) N Engl J Med , vol.342 , pp. 1802-1813
    • Lue, T.F.1
  • 24
    • 37749011562 scopus 로고    scopus 로고
    • Viagra (sildenafil citrate) [prescribing information]. New York, NY; Pfizer Inc; October, 2006
    • Viagra (sildenafil citrate) [prescribing information]. New York, NY; Pfizer Inc; October, 2006
  • 25
    • 37749003888 scopus 로고    scopus 로고
    • Levitra (vardenafil HCl) [prescribing information]. West Haven, CT; Research Triangle Park, NC; and Kenilworth, NJ; Bayer Healthcare, GlaxoSmithKline, and Schering-Plough Corporation; March, 2007
    • Levitra (vardenafil HCl) [prescribing information]. West Haven, CT; Research Triangle Park, NC; and Kenilworth, NJ; Bayer Healthcare, GlaxoSmithKline, and Schering-Plough Corporation; March, 2007
  • 26
    • 70349707458 scopus 로고    scopus 로고
    • tadalafil, prescribing information, Eli Lilly and Company; January
    • Cialis (tadalafil) [prescribing information]. Indianapolis, IN; Eli Lilly and Company; January, 2007
    • (2007) Indianapolis
    • Cialis1
  • 27
    • 37749051358 scopus 로고    scopus 로고
    • Vardenafil extended 12 hour data abstract
    • Abstract 44
    • Gittelman M. Vardenafil extended 12 hour data abstract. J Sex Med 2006;3:28-29 [Abstract 44]
    • (2006) J Sex Med , vol.3 , pp. 28-29
    • Gittelman, M.1
  • 28
    • 1642341938 scopus 로고    scopus 로고
    • The sexual habits of British men and women over 40 years old
    • Eardley I, Dean J, Barnes T, et al. The sexual habits of British men and women over 40 years old. BJU Int 2004;93:563-7
    • (2004) BJU Int , vol.93 , pp. 563-567
    • Eardley, I.1    Dean, J.2    Barnes, T.3
  • 29
    • 37749004093 scopus 로고    scopus 로고
    • Tadalafil in men with erectile dysfunction and spinal cord injury [abstract]
    • Presented at: April 5-8, Paris, France, Abstract 469
    • Giuliano F, Sanchez Ramos A, Loechner Ernst D, et al. Tadalafil in men with erectile dysfunction and spinal cord injury [abstract]. Presented at: the 21st Annual EAU Congress; April 5-8, 2006; Paris, France. [Abstract 469]
    • (2006) the 21st Annual EAU Congress
    • Giuliano, F.1    Sanchez Ramos, A.2    Loechner Ernst, D.3
  • 30
    • 13844291271 scopus 로고    scopus 로고
    • Trial Evaluating the Activity of Tadalafil for Erectile Dysfunction-United States (TREATED-US) Study Group. Efficacy, safety, and treatment satisfaction of tadalafil versus placebo in patients with erectile dysfunction evaluated at tertiary-care academic centers
    • Carson C, Shabsigh R, Segal S, et al; Trial Evaluating the Activity of Tadalafil for Erectile Dysfunction-United States (TREATED-US) Study Group. Efficacy, safety, and treatment satisfaction of tadalafil versus placebo in patients with erectile dysfunction evaluated at tertiary-care academic centers. Urology 2005;65:353-9
    • (2005) Urology , vol.65 , pp. 353-359
    • Carson, C.1    Shabsigh, R.2    Segal, S.3
  • 31
    • 33847361439 scopus 로고    scopus 로고
    • Phosphodiesterase type 5 inhibitors' extended duration of response as a variable in the treatment of erectile dysfunction
    • Dunn ME, Althof SE, Perelman MA. Phosphodiesterase type 5 inhibitors' extended duration of response as a variable in the treatment of erectile dysfunction. Int J Impot Res 2007;19: 119-23
    • (2007) Int J Impot Res , vol.19 , pp. 119-123
    • Dunn, M.E.1    Althof, S.E.2    Perelman, M.A.3
  • 32
    • 37749000163 scopus 로고    scopus 로고
    • Evolving understanding of erectile dysfunction strategies for diagnosis and intervention
    • Evolving understanding of erectile dysfunction strategies for diagnosis and intervention. J Sex Med 2006;3(Suppl 1): 10-13
    • (2006) J Sex Med , vol.3 , Issue.SUPPL. 1 , pp. 10-13
  • 33
    • 0036754094 scopus 로고    scopus 로고
    • Achieving treatment optimization with sildenafil citrate (Viagra) in patients with erectile dysfunction
    • McCullough AR, Barada JH, Fawzy A, et al. Achieving treatment optimization with sildenafil citrate (Viagra) in patients with erectile dysfunction. Urology 2002;60:28-38
    • (2002) Urology , vol.60 , pp. 28-38
    • McCullough, A.R.1    Barada, J.H.2    Fawzy, A.3
  • 34
    • 7444270532 scopus 로고    scopus 로고
    • Integrated analysis examining first-dose success, success by dose, and maintenance of success among men taking tadalafil for erectile dysfunction
    • Schulman CC, Shen W, Stothard DR, Schmitt H. Integrated analysis examining first-dose success, success by dose, and maintenance of success among men taking tadalafil for erectile dysfunction. Urology 2004;64:783-8
    • (2004) Urology , vol.64 , pp. 783-788
    • Schulman, C.C.1    Shen, W.2    Stothard, D.R.3    Schmitt, H.4
  • 35
    • 10644262090 scopus 로고    scopus 로고
    • Vardenafil provides reliable efficacy over time in men with erectile dysfunction
    • Montorsi F, Hellstrom WJ, Valiquette L, et al. Vardenafil provides reliable efficacy over time in men with erectile dysfunction. Urology 2004;64:1187-95
    • (2004) Urology , vol.64 , pp. 1187-1195
    • Montorsi, F.1    Hellstrom, W.J.2    Valiquette, L.3
  • 36
    • 25844503715 scopus 로고    scopus 로고
    • Sustained efficacy and safety of vardenafil for treatment of erectile dysfunction: A randomized, double-blind, placebo-controlled study
    • Valiquette L, Young JM, Moncada I, et al. Sustained efficacy and safety of vardenafil for treatment of erectile dysfunction: a randomized, double-blind, placebo-controlled study. Mayo Clin Proc 2005;80:1291-7
    • (2005) Mayo Clin Proc , vol.80 , pp. 1291-1297
    • Valiquette, L.1    Young, J.M.2    Moncada, I.3
  • 37
    • 33749859517 scopus 로고    scopus 로고
    • First-dose success with vardenafil in men with erectile dysfunction and associated comorbidities: RELY-I
    • Valiquette L, Montorsi F, Auerbach S. First-dose success with vardenafil in men with erectile dysfunction and associated comorbidities: RELY-I. Int J Clin Pract 2006;60: 1378-85
    • (2006) Int J Clin Pract , vol.60 , pp. 1378-1385
    • Valiquette, L.1    Montorsi, F.2    Auerbach, S.3
  • 38
    • 34250619107 scopus 로고    scopus 로고
    • Vardenafil provides initial and subsequent penetration reliability in patients with a high rate of comorbidities and erectile dysfunction: The reliability-vardenafil for erectile dysfunction II (RELY-II) trial
    • Abstract 154
    • Valiquette L, Auerbach S, Nathan HP, et al. Vardenafil provides initial and subsequent penetration reliability in patients with a high rate of comorbidities and erectile dysfunction: the reliability-vardenafil for erectile dysfunction II (RELY-II) trial. J Sex Med 2006;3:162-3 [Abstract 154]
    • (2006) J Sex Med , vol.3 , pp. 162-163
    • Valiquette, L.1    Auerbach, S.2    Nathan, H.P.3
  • 39
    • 0036124839 scopus 로고    scopus 로고
    • Onset and duration of action of sildenafil for the treatment of erectile dysfunction
    • Eardley I, Ellis P, Boolell M, Wulff M. Onset and duration of action of sildenafil for the treatment of erectile dysfunction. Br J Clin Pharmacol 2002;53(Suppl 1):61-5S
    • (2002) Br J Clin Pharmacol , vol.53 , Issue.SUPPL. 1
    • Eardley, I.1    Ellis, P.2    Boolell, M.3    Wulff, M.4
  • 40
    • 0042734896 scopus 로고    scopus 로고
    • Minimal time to successful intercourse after sildenafil citrate: Results of a randomized, double-blind, placebo-controlled trial
    • Padma-Nathan H, Stecher VJ, Sweeney M, et al. Minimal time to successful intercourse after sildenafil citrate: results of a randomized, double-blind, placebo-controlled trial. Urology 2003;62:400-3
    • (2003) Urology , vol.62 , pp. 400-403
    • Padma-Nathan, H.1    Stecher, V.J.2    Sweeney, M.3
  • 41
    • 15844430082 scopus 로고    scopus 로고
    • Duration of action of sildenafil citrate in men with erectile dysfunction
    • Gingell C, Sultana SR, Wulff MB, Gepi-Attee S. Duration of action of sildenafil citrate in men with erectile dysfunction. J Sex Med 2004;1:179-84
    • (2004) J Sex Med , vol.1 , pp. 179-184
    • Gingell, C.1    Sultana, S.R.2    Wulff, M.B.3    Gepi-Attee, S.4
  • 42
    • 2942711783 scopus 로고    scopus 로고
    • The efficacy and safety of tadalafil: An update
    • Carson CC, Rajfer J, Eardley I, et al. The efficacy and safety of tadalafil: an update. BJU Int 2004;93:1276-81
    • (2004) BJU Int , vol.93 , pp. 1276-1281
    • Carson, C.C.1    Rajfer, J.2    Eardley, I.3
  • 43
    • 28544436236 scopus 로고    scopus 로고
    • Sexual intercourse attempt patterns with two dosing regimens of tadalafil in men with erectile dysfunction: Results from the SURE study in 14 European countries
    • Moncada I, Damber J-E, Mirone V, et al. Sexual intercourse attempt patterns with two dosing regimens of tadalafil in men with erectile dysfunction: results from the SURE study in 14 European countries. J Sex Med 2005;2:688-74
    • (2005) J Sex Med , vol.2 , pp. 688-674
    • Moncada, I.1    Damber, J.-E.2    Mirone, V.3
  • 44
    • 23944452949 scopus 로고    scopus 로고
    • Penetration and maintenance of erection with vardenafil: A time-from-dosing analysis
    • Valiquette L, Montorsi F, Hellstrom WJ, et al. Penetration and maintenance of erection with vardenafil: a time-from-dosing analysis. Can J Urol 2005;12:2687-98
    • (2005) Can J Urol , vol.12 , pp. 2687-2698
    • Valiquette, L.1    Montorsi, F.2    Hellstrom, W.J.3
  • 45
    • 33749250591 scopus 로고    scopus 로고
    • Extended duration of efficacy of vardenafil when taken 8 hours before intercourse: A randomized, double-blind, placebo-controlled study
    • for the Vardenafil Study Group
    • Porst H, Sharlip ID, Hatzichristou D, et al; for the Vardenafil Study Group. Extended duration of efficacy of vardenafil when taken 8 hours before intercourse: a randomized, double-blind, placebo-controlled study. Eur Urol 2006;50:1086-94
    • (2006) Eur Urol , vol.50 , pp. 1086-1094
    • Porst, H.1    Sharlip, I.D.2    Hatzichristou, D.3
  • 46
    • 0033518552 scopus 로고    scopus 로고
    • Sildenafil for treatment of erectile dysfunction in men with diabetes: A randomized controlled trial. Sildenafil Diabetes Study Group
    • Rendell MS, Rajfer J, Wicker PA, Smith MD. Sildenafil for treatment of erectile dysfunction in men with diabetes: a randomized controlled trial. Sildenafil Diabetes Study Group. JAMA 1999;281:421-6
    • (1999) JAMA , vol.281 , pp. 421-426
    • Rendell, M.S.1    Rajfer, J.2    Wicker, P.A.3    Smith, M.D.4
  • 47
    • 0041364523 scopus 로고    scopus 로고
    • Sildenafil citrate for treatment of erectile dysfunction in men with type 1 diabetes: Results of a randomized controlled trial
    • Stuckey BG, Jadzinsky MN, Murphy LJ, et al. Sildenafil citrate for treatment of erectile dysfunction in men with type 1 diabetes: results of a randomized controlled trial. Diabetes Care 2003;26:279-84
    • (2003) Diabetes Care , vol.26 , pp. 279-284
    • Stuckey, B.G.1    Jadzinsky, M.N.2    Murphy, L.J.3
  • 49
    • 22144453867 scopus 로고    scopus 로고
    • The efficacy of tadalafil in clinical populations
    • Lewis RW, Sadovsky R, Eardley I, et al. The efficacy of tadalafil in clinical populations. J Sex Med 2005;2:517-31
    • (2005) J Sex Med , vol.2 , pp. 517-531
    • Lewis, R.W.1    Sadovsky, R.2    Eardley, I.3
  • 50
    • 0042405173 scopus 로고    scopus 로고
    • Vardenafil, a new phosphodiesterase type 5 inhibitor, in the treatment of erectile dysfunction in men with diabetes: A multicenter double-blind placebo-controlled fixed-dose study
    • Goldstein I, Young JM, Fischer J, et al. Vardenafil, a new phosphodiesterase type 5 inhibitor, in the treatment of erectile dysfunction in men with diabetes: a multicenter double-blind placebo-controlled fixed-dose study. Diabetes Care 2003;26:777-83
    • (2003) Diabetes Care , vol.26 , pp. 777-783
    • Goldstein, I.1    Young, J.M.2    Fischer, J.3
  • 51
    • 33947108390 scopus 로고    scopus 로고
    • Efficacy and safety of vardenafil, a selective phosphodiesterase 5 inhibitor, in type 1 diabetic patients with erectile dysfunction
    • Abstract 514-P
    • Ziegler D, Merfort F, Van Ahlen H, et al. Efficacy and safety of vardenafil, a selective phosphodiesterase 5 inhibitor, in type 1 diabetic patients with erectile dysfunction. Diabetes 2005;54:A127 [Abstract 514-P]
    • (2005) Diabetes , vol.54
    • Ziegler, D.1    Merfort, F.2    Van Ahlen, H.3
  • 52
    • 28444487883 scopus 로고    scopus 로고
    • Safety and efficacy of vardenafil, a selective phosphodiesterase 5 inhibitor, in patients with erectile dysfunction and arterial hypertension treated with multiple antihypertensives
    • van Ahlen H, Wahle K, Kupper W, et al. Safety and efficacy of vardenafil, a selective phosphodiesterase 5 inhibitor, in patients with erectile dysfunction and arterial hypertension treated with multiple antihypertensives. J Sex Med 2005;2:856-64
    • (2005) J Sex Med , vol.2 , pp. 856-864
    • van Ahlen, H.1    Wahle, K.2    Kupper, W.3
  • 53
    • 11144256971 scopus 로고    scopus 로고
    • Sildenafil citrate for erectile dysfunction in men receiving multiple antihypertensive agents: A randomized controlled trial
    • Pickering TG, Shepherd AM, Puddey I, et al. Sildenafil citrate for erectile dysfunction in men receiving multiple antihypertensive agents: a randomized controlled trial. Am J Hypertens 2004;17:1135-42
    • (2004) Am J Hypertens , vol.17 , pp. 1135-1142
    • Pickering, T.G.1    Shepherd, A.M.2    Puddey, I.3
  • 54
    • 33845788317 scopus 로고    scopus 로고
    • Efficacy and safety of tadalafil in men with erectile dysfunction with a high prevalence of comorbid conditions: Results from MOMENTUS: multiple observations in men with erectile dysfunction in National Tadalafil Study in the US
    • Goldstein I, Kim E, Steers WD, et al. Efficacy and safety of tadalafil in men with erectile dysfunction with a high prevalence of comorbid conditions: results from MOMENTUS: multiple observations in men with erectile dysfunction in National Tadalafil Study in the US. J Sex Med 2007;4:166-75
    • (2007) J Sex Med , vol.4 , pp. 166-175
    • Goldstein, I.1    Kim, E.2    Steers, W.D.3
  • 55
    • 0000379292 scopus 로고    scopus 로고
    • Vardenafil improves erectile function in men with significant comorbidities association with erectile dysfunction
    • Abstract 714
    • Goldfischer E, Eardley I, Segerson T. Vardenafil improves erectile function in men with significant comorbidities association with erectile dysfunction. J Urol 2002;167:178 [Abstract 714]
    • (2002) J Urol , vol.167 , pp. 178
    • Goldfischer, E.1    Eardley, I.2    Segerson, T.3
  • 56
    • 0036754975 scopus 로고    scopus 로고
    • Efficacy and safety of sildenafil citrate (Viagra) in black and Hispanic American men
    • Young JM, Bennett C, Gilhooly P, et al. Efficacy and safety of sildenafil citrate (Viagra) in black and Hispanic American men. Urology 2002;60:39-48
    • (2002) Urology , vol.60 , pp. 39-48
    • Young, J.M.1    Bennett, C.2    Gilhooly, P.3
  • 57
    • 27744508710 scopus 로고    scopus 로고
    • The efficacy and safety of PDE5 inhibitors
    • Rashid A. The efficacy and safety of PDE5 inhibitors. Clin Cornerstone 2005;7:47-56
    • (2005) Clin Cornerstone , vol.7 , pp. 47-56
    • Rashid, A.1
  • 58
    • 15244360676 scopus 로고    scopus 로고
    • Visual field defect and intracerebral hemorrhage associated with use of vardenafil (Levitra)
    • McGee HT, Egan RA, Clark WM. Visual field defect and intracerebral hemorrhage associated with use of vardenafil (Levitra). Neurology 2005;64:1095-6
    • (2005) Neurology , vol.64 , pp. 1095-1096
    • McGee, H.T.1    Egan, R.A.2    Clark, W.M.3
  • 59
    • 27744466227 scopus 로고    scopus 로고
    • PDE5 inhibitors and permanent visual loss
    • Tomsak R. PDE5 inhibitors and permanent visual loss. Int J Impot Res 2005;17:547-9
    • (2005) Int J Impot Res , vol.17 , pp. 547-549
    • Tomsak, R.1
  • 60
    • 37349027055 scopus 로고    scopus 로고
    • and Drug Administration, online. Available from, Last accessed 07 August
    • US Food and Drug Administration. FDA alert for healthcare professionals (vardenafil) [online. Available from http://www. fda.gov/cder/drug/InfoSheets/ HCP/vardenafilHCP.pdf/ [Last accessed 07 August 2007]
    • (2007) FDA alert for healthcare professionals (vardenafil)
    • Food, U.S.1
  • 61
    • 31544463258 scopus 로고    scopus 로고
    • Non-arteritic anterior ischaemic optic neuropathy and the treatment of erectile dysfunction
    • McGwin G Jr, Vaphiades MS, Hall TA, Owsley C. Non-arteritic anterior ischaemic optic neuropathy and the treatment of erectile dysfunction. Br J Ophthalmol 2006;90:154-7
    • (2006) Br J Ophthalmol , vol.90 , pp. 154-157
    • McGwin Jr, G.1    Vaphiades, M.S.2    Hall, T.A.3    Owsley, C.4
  • 62
    • 34250675210 scopus 로고    scopus 로고
    • Cardiovascular safety of vardenafil in patients on antihypertensive therapies and alpha-blockers: Finding from analyses of 17 placebo-controlled clinical trials
    • Abstract 873
    • Hellstrom WJG, White WB, Sprenger K, et al. Cardiovascular safety of vardenafil in patients on antihypertensive therapies and alpha-blockers: finding from analyses of 17 placebo-controlled clinical trials. J Urol 2005;173:200 [Abstract 873]
    • (2005) J Urol , vol.173 , pp. 200
    • Hellstrom, W.J.G.1    White, W.B.2    Sprenger, K.3
  • 63
    • 7944224294 scopus 로고    scopus 로고
    • Simultaneous administration of vardenafil and tamsulosin does not induce clinically significant hypotension in patients with benign prostatic hyperplasia
    • Auerbach SM, Gittelman M, Mazzu A, et al. Simultaneous administration of vardenafil and tamsulosin does not induce clinically significant hypotension in patients with benign prostatic hyperplasia. Urology 2004;64:998-1003
    • (2004) Urology , vol.64 , pp. 998-1003
    • Auerbach, S.M.1    Gittelman, M.2    Mazzu, A.3
  • 64
    • 5444234921 scopus 로고    scopus 로고
    • Interaction between the phosphodiesterase 5 inhibitor, tadalafil and 2 alpha-blockers, doxazosin and tamsulosin in healthy normotensive men
    • Kloner RA, Jackson G, Emmick JT, et al. Interaction between the phosphodiesterase 5 inhibitor, tadalafil and 2 alpha-blockers, doxazosin and tamsulosin in healthy normotensive men. J Urol 2004;172(5 Pt 1):1935-40
    • (2004) J Urol , vol.172 , Issue.5 PART 1 , pp. 1935-1940
    • Kloner, R.A.1    Jackson, G.2    Emmick, J.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.