-
1
-
-
33748329399
-
Molecular details of cAMP generation in mammalian cells: A tale of two systems
-
Kamenetsky M., Middelhaufe S., Bank EM, Levin LR, Buck J., Steegborn C.: Molecular details of cAMP generation in mammalian cells: a tale of two systems. J Mol Biol 2006 ; 362 (4). 623-639.
-
(2006)
J Mol Biol
, vol.362
, Issue.4
, pp. 623-639
-
-
Kamenetsky, M.1
Middelhaufe, S.2
Bank, E.M.3
Levin, L.R.4
Buck, J.5
Steegborn, C.6
-
2
-
-
33748686575
-
Cyclic nucleotide phosphodiesterases: Molecular regulation to clinical use
-
Bender AT, Beavo JA: Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use. Pharmacol Rev 2006 ; 58 (3). 488-520.
-
(2006)
Pharmacol Rev
, vol.58
, Issue.3
, pp. 488-520
-
-
Bender, A.T.1
Beavo, J.A.2
-
3
-
-
30044446499
-
Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies
-
Lerner A., Epstein PM: Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies. Biochem J 2006 ; 393 (pt 1). 21-41.
-
(2006)
Biochem J
, vol.393
, Issue.1
, pp. 21-41
-
-
Lerner, A.1
Epstein, P.M.2
-
4
-
-
33845927898
-
Modulation of Leydig cell function by cyclic nucleotide phosphodiesterase 8A
-
Vasta V., Shimizu-Albergine M., Beavo JA: Modulation of Leydig cell function by cyclic nucleotide phosphodiesterase 8A. Proc Natl Acad Sci U S A 2006 ; 103: 19925-19930.
-
(2006)
Proc Natl Acad Sci U S a
, vol.103
, pp. 19925-19930
-
-
Vasta, V.1
Shimizu-Albergine, M.2
Beavo, J.A.3
-
5
-
-
0036139840
-
Update on the therapeutic potential of PDE4 inhibitors
-
Dyke HJ, Montana JG: Update on the therapeutic potential of PDE4 inhibitors. Expert Opin Investig Drugs 2002 ; 11 (1). 1-13.
-
(2002)
Expert Opin Investig Drugs
, vol.11
, Issue.1
, pp. 1-13
-
-
Dyke, H.J.1
Montana, J.G.2
-
7
-
-
1342264246
-
Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4)
-
O'Donnell JM, Zhang HT: Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4). Trends Pharmacol Sci 2004 ; 25 (3). 158-163.
-
(2004)
Trends Pharmacol Sci
, vol.25
, Issue.3
, pp. 158-163
-
-
O'Donnell, J.M.1
Zhang, H.T.2
-
8
-
-
31144433061
-
Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents
-
Lugnier C.: Cyclic nucleotide phosphodiesterase (PDE) superfamily: a new target for the development of specific therapeutic agents. Pharmacol Ther 2006 ; 109 (3). 366-398.
-
(2006)
Pharmacol Ther
, vol.109
, Issue.3
, pp. 366-398
-
-
Lugnier, C.1
-
9
-
-
33846975147
-
Role of phosphodiesterases in neurological and psychiatric disease
-
Hebb AL, Robertson HA: Role of phosphodiesterases in neurological and psychiatric disease. Curr Opin Pharmacol 2007 ; 7 (1). 86-92.
-
(2007)
Curr Opin Pharmacol
, vol.7
, Issue.1
, pp. 86-92
-
-
Hebb, A.L.1
Robertson, H.A.2
-
10
-
-
0025215701
-
Isolation and characterization of mutants constitutive for expression of the fbp1 gene of Schizosaccharomyces pombe
-
Hoffman CS, Winston F.: Isolation and characterization of mutants constitutive for expression of the fbp1 gene of Schizosaccharomyces pombe. Genetics 1990 ; 124 (4). 807-816.
-
(1990)
Genetics
, vol.124
, Issue.4
, pp. 807-816
-
-
Hoffman, C.S.1
Winston, F.2
-
11
-
-
14644435106
-
Glucose sensing via the protein kinase a pathway in Schizosaccharomyces pombe
-
Hoffman CS: Glucose sensing via the protein kinase A pathway in Schizosaccharomyces pombe. Biochem Soc Trans 2005 ; 33 (pt 1). 257-260.
-
(2005)
Biochem Soc Trans
, vol.33
, Issue.1
, pp. 257-260
-
-
Hoffman, C.S.1
-
12
-
-
15244359991
-
Except in every detail: Comparing and contrasting G protein signaling in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Eukaryotic
-
Hoffman CS: Except in every detail: comparing and contrasting G protein signaling in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Eukaryotic Cell 2005 ; 4: 495-503.
-
(2005)
Cell
, vol.4
, pp. 495-503
-
-
Hoffman, C.S.1
-
13
-
-
0029954766
-
Activation and regulation of the Spc1 stress-activated protein kinase in Schizosaccharomyces pombe
-
Degols G., Shiozaki K., Russell P.: Activation and regulation of the Spc1 stress-activated protein kinase in Schizosaccharomyces pombe. Mol Cell Biol 1996 ; 16 (6). 2870-2877.
-
(1996)
Mol Cell Biol
, vol.16
, Issue.6
, pp. 2870-2877
-
-
Degols, G.1
Shiozaki, K.2
Russell, P.3
-
14
-
-
0029997856
-
The wis1 signal transduction pathway is required for expression of cAMP- repressed genes in fission yeast
-
Stettler S., Warbrick E., Prochnik S., Mackie S., Fantes P.: The wis1 signal transduction pathway is required for expression of cAMP- repressed genes in fission yeast. J Cell Sci 1996 ; 109 (pt 7). 1927-1935.
-
(1996)
J Cell Sci
, vol.109
, Issue.7
, pp. 1927-1935
-
-
Stettler, S.1
Warbrick, E.2
Prochnik, S.3
MacKie, S.4
Fantes, P.5
-
15
-
-
2942670792
-
Suppressors of an adenylate cyclase deletion in the fission yeast Schizosaccharomyces pombe. Eukaryotic
-
Stiefel J., Wang L., Kelly DA, Janoo RTK, Seitz J., Whitehall SK,, et al. Suppressors of an adenylate cyclase deletion in the fission yeast Schizosaccharomyces pombe. Eukaryotic Cell 2004 ; 3 (3). 610-619.
-
(2004)
Cell
, vol.3
, Issue.3
, pp. 610-619
-
-
Stiefel, J.1
Wang, L.2
Kelly, D.A.3
Rtk, J.4
Seitz, J.5
Whitehall, S.K.6
-
16
-
-
29144469377
-
Schizosaccharomyces pombe adenylate cyclase suppressor mutations suggest a role for cAMP phosphodiesterase regulation in feedback control of glucose/cAMP signaling
-
Wang L., Griffiths K., Zhang YH, Ivey FD, Hoffman CS: Schizosaccharomyces pombe adenylate cyclase suppressor mutations suggest a role for cAMP phosphodiesterase regulation in feedback control of glucose/cAMP signaling. Genetics 2005 ; 171: 1523-1533.
-
(2005)
Genetics
, vol.171
, pp. 1523-1533
-
-
Wang, L.1
Griffiths, K.2
Zhang, Y.H.3
Ivey, F.D.4
Hoffman, C.S.5
-
17
-
-
0026742292
-
Reduction in the intracellular cAMP level triggers initiation of sexual development in fission yeast
-
Mochizuki N., Yamamoto M.: Reduction in the intracellular cAMP level triggers initiation of sexual development in fission yeast. Mol Gen Genet 1992 ; 233 (1-2). 17-24.
-
(1992)
Mol Gen Genet
, vol.233
, Issue.1-2
, pp. 17-24
-
-
Mochizuki, N.1
Yamamoto, M.2
-
18
-
-
8844221233
-
Relationship of stereochemical and skeletal diversity of small molecules to cellular measurement space
-
Kim YK, Arai MA, Arai T., Lamenzo JO, Dean EF III, Patterson N.,, et al. Relationship of stereochemical and skeletal diversity of small molecules to cellular measurement space. J Am Chem Soc 2004 ; 126 (45). 14740-14745.
-
(2004)
J Am Chem Soc
, vol.126
, Issue.45
, pp. 14740-14745
-
-
Kim, Y.K.1
Ma, A.2
Arai, T.3
Lamenzo, J.O.4
Dean III, E.F.5
Patterson, N.6
-
19
-
-
33846842437
-
Synthesis and cellular profiling of diverse organosilicon small molecules
-
Franz AK, Dreyfuss PD, Schreiber SL: Synthesis and cellular profiling of diverse organosilicon small molecules. J Am Chem Soc 2007 ; 129 (5). 1020-1021.
-
(2007)
J Am Chem Soc
, vol.129
, Issue.5
, pp. 1020-1021
-
-
Franz, A.K.1
Dreyfuss, P.D.2
Schreiber, S.L.3
-
20
-
-
0035911641
-
Diazepam and rolipram differentially inhibit cyclic AMP-specific phosphodiesterases PDE4A1 and PDE4B3 in the mouse
-
Cherry JA, Thompson BE, Pho V.: Diazepam and rolipram differentially inhibit cyclic AMP-specific phosphodiesterases PDE4A1 and PDE4B3 in the mouse. Biochim Biophys Acta 2001 ; 1518 (1-2). 27-35.
-
(2001)
Biochim Biophys Acta
, vol.1518
, Issue.1-2
, pp. 27-35
-
-
Cherry, J.A.1
Thompson, B.E.2
Pho, V.3
-
21
-
-
0032555138
-
Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase
-
Soderling SH, Bayuga SJ, Beavo JA: Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase. Proc Natl Acad Sci U S A 1998 ; 95 (15). 8991-8996.
-
(1998)
Proc Natl Acad Sci U S a
, vol.95
, Issue.15
, pp. 8991-8996
-
-
Sh, S.1
Bayuga, S.J.2
Beavo, J.A.3
-
22
-
-
4444349218
-
Molecular determinants for cyclic nucleotide binding to the regulatory domains of phosphodiesterase 2A
-
Wu AY, Tang XB, Martinez SE, Ikeda K., Beavo JA: Molecular determinants for cyclic nucleotide binding to the regulatory domains of phosphodiesterase 2A. J Biol Chem 2004 ; 279 (36). 37928-37938.
-
(2004)
J Biol Chem
, vol.279
, Issue.36
, pp. 37928-37938
-
-
Wu, A.Y.1
Tang, X.B.2
Martinez, S.E.3
Ikeda, K.4
Beavo, J.A.5
-
23
-
-
0025944872
-
Interaction between ran1+ protein kinase and cAMP dependent protein kinase as negative regulators of fission yeast meiosis
-
DeVoti J., Seydoux G., Beach D., McLeod M.: Interaction between ran1+ protein kinase and cAMP dependent protein kinase as negative regulators of fission yeast meiosis. EMBO J 1991 ; 10 (12). 3759-3768.
-
(1991)
EMBO J
, vol.10
, Issue.12
, pp. 3759-3768
-
-
Devoti, J.1
Seydoux, G.2
Beach, D.3
McLeod, M.4
-
24
-
-
17844378717
-
Direct activation of fission yeast adenylate cyclase by the Gpa2 Gα of the glucose signaling pathway
-
Ivey FD, Hoffman CS Direct activation of fission yeast adenylate cyclase by the Gpa2 Gα of the glucose signaling pathway. Proc Natl Acad Sci U S A 2005 ; 102 (17). 6108-6113.
-
(2005)
Proc Natl Acad Sci U S a
, vol.102
, Issue.17
, pp. 6108-6113
-
-
Ivey, F.D.1
Hoffman, C.S.2
-
25
-
-
0028100448
-
Glucose repression of fbp1 transcription of Schizosaccharomyces pombe is partially regulated by adenylate cyclase activation by a G protein α subunit encoded by gpa2 (git8)
-
Nocero M., Isshiki T., Yamamoto M., Hoffman CS: Glucose repression of fbp1 transcription of Schizosaccharomyces pombe is partially regulated by adenylate cyclase activation by a G protein α subunit encoded by gpa2 (git8). Genetics 1994 ; 138 (1). 39-45.
-
(1994)
Genetics
, vol.138
, Issue.1
, pp. 39-45
-
-
Nocero, M.1
Isshiki, T.2
Yamamoto, M.3
Hoffman, C.S.4
-
26
-
-
0033786755
-
Glucose monitoring in fission yeast via the gpa2 Gα, the git5 Gβ, and the git3 putative glucose receptor
-
Welton RM, Hoffman CS: Glucose monitoring in fission yeast via the gpa2 Gα, the git5 Gβ, and the git3 putative glucose receptor. Genetics 2000 ; 156: 513-521.
-
(2000)
Genetics
, vol.156
, pp. 513-521
-
-
Welton, R.M.1
Hoffman, C.S.2
-
27
-
-
0032523783
-
Regulation of the fission yeast transcription factor Pap1 by oxidative stress: Requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1
-
Toone WM, Kuge S., Samuels M., Morgan BA, Toda T., Jones N.: Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1. Genes Dev 1998 ; 12 (10). 1453-1463.
-
(1998)
Genes Dev
, vol.12
, Issue.10
, pp. 1453-1463
-
-
Toone, W.M.1
Kuge, S.2
Samuels, M.3
Morgan, B.A.4
Toda, T.5
Jones, N.6
-
28
-
-
0025977196
-
Fission yeast genes that confer resistance to staurosporine encode an AP-1-like transcription factor and a protein kinase related to the mammalian ERK1/MAP2 and budding yeast FUS3 and KSS1 kinases
-
Toda T., Shimanuki M., Yanagida M.: Fission yeast genes that confer resistance to staurosporine encode an AP-1-like transcription factor and a protein kinase related to the mammalian ERK1/MAP2 and budding yeast FUS3 and KSS1 kinases. Genes Dev 1991 ; 5 (1). 60-73.
-
(1991)
Genes Dev
, vol.5
, Issue.1
, pp. 60-73
-
-
Toda, T.1
Shimanuki, M.2
Yanagida, M.3
-
29
-
-
0033003760
-
A simple statistical parameter for use in evaluation and validation of high throughput screening assays
-
Zhang JH, Chung TD, Oldenburg KR: A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 1999 ; 4 (2). 67-73.
-
(1999)
J Biomol Screen
, vol.4
, Issue.2
, pp. 67-73
-
-
Zhang, J.H.1
Chung, T.D.2
Oldenburg, K.R.3
-
30
-
-
0025771976
-
Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae
-
Colicelli J., Nicolette C., Birchmeier C., Rodgers L., Riggs M., Wigler M.: Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 1991 ; 88 (7). 2913-2917.
-
(1991)
Proc Natl Acad Sci U S a
, vol.88
, Issue.7
, pp. 2913-2917
-
-
Colicelli, J.1
Nicolette, C.2
Birchmeier, C.3
Rodgers, L.4
Riggs, M.5
Wigler, M.6
-
31
-
-
0027138677
-
Use of a yeast expression system for the isolation and analysis of drug-resistant mutants of a mammalian phosphodiesterase
-
Pillai R., Kytle K., Reyes A., Colicelli J.: Use of a yeast expression system for the isolation and analysis of drug-resistant mutants of a mammalian phosphodiesterase. Proc Natl Acad Sci U S A 1993 ; 90 (24). 11970-11974.
-
(1993)
Proc Natl Acad Sci U S a
, vol.90
, Issue.24
, pp. 11970-11974
-
-
Pillai, R.1
Kytle, K.2
Reyes, A.3
Colicelli, J.4
-
33
-
-
0020000847
-
Characteristic behavioural alterations in rats induced by rolipram and other selective adenosine cyclic 3′, 5′-monophosphate phosphodiesterase inhibitors
-
Wachtel H.: Characteristic behavioural alterations in rats induced by rolipram and other selective adenosine cyclic 3′, 5′-monophosphate phosphodiesterase inhibitors. Psychopharmacology (Berl) 1982 ; 77 (4). 309-316.
-
(1982)
Psychopharmacology (Berl)
, vol.77
, Issue.4
, pp. 309-316
-
-
Wachtel, H.1
-
34
-
-
0020693045
-
Potential antidepressant activity of rolipram and other selective cyclic adenosine 3′,5′-monophosphate phosphodiesterase inhibitors
-
Wachtel H.: Potential antidepressant activity of rolipram and other selective cyclic adenosine 3′,5′-monophosphate phosphodiesterase inhibitors. Neuropharmacology 1983 ; 22 (3). 267-272.
-
(1983)
Neuropharmacology
, vol.22
, Issue.3
, pp. 267-272
-
-
Wachtel, H.1
-
35
-
-
0035976546
-
Localization of phosphodiesterase-4 isoforms in the medulla and nodose ganglion of the squirrel monkey
-
Lamontagne S., Meadows E., Luk P., Normandin D., Muise E., Boulet L.,, et al. Localization of phosphodiesterase-4 isoforms in the medulla and nodose ganglion of the squirrel monkey. Brain Res 2001 ; 920 (1-2). 84-96.
-
(2001)
Brain Res
, vol.920
, Issue.1-2
, pp. 84-96
-
-
Lamontagne, S.1
Meadows, E.2
Luk, P.3
Normandin, D.4
Muise, E.5
Boulet, L.6
-
36
-
-
0037105945
-
Differential distribution of PDE4D splice variant mRNAs in rat brain suggests association with specific pathways and presynaptical localization
-
Miro X., Perez-Torres S., Puigdomenech P., Palacios JM, Mengod G.: Differential distribution of PDE4D splice variant mRNAs in rat brain suggests association with specific pathways and presynaptical localization. Synapse 2002 ; 45 (4). 259-269.
-
(2002)
Synapse
, vol.45
, Issue.4
, pp. 259-269
-
-
Miro, X.1
Perez-Torres, S.2
Puigdomenech, P.3
Palacios, J.M.4
Mengod, G.5
-
37
-
-
33748324543
-
Flavonoids attenuate cardiovascular disease, inhibit phosphodiesterase, and modulate lipid homeostasis in adipose tissue and liver
-
Maywood)
-
Peluso MR: Flavonoids attenuate cardiovascular disease, inhibit phosphodiesterase, and modulate lipid homeostasis in adipose tissue and liver. Exp Biol Med (Maywood) 2006 ; 231 (8). 1287-1299.
-
(2006)
Exp Biol Med
, vol.231
, Issue.8
, pp. 1287-1299
-
-
Peluso, M.R.1
-
38
-
-
0032889828
-
Effects of visnagin on cyclic nucleotide phosphodiesterases and their role in its inhibitory effects on vascular smooth muscle contraction
-
Duarte J., Lugnier C., Torres AI, Perez-Vizcaino F., Zarzuelo A., Tamargo J.: Effects of visnagin on cyclic nucleotide phosphodiesterases and their role in its inhibitory effects on vascular smooth muscle contraction. Gen Pharmacol 1999 ; 32 (1). 71-74.
-
(1999)
Gen Pharmacol
, vol.32
, Issue.1
, pp. 71-74
-
-
Duarte, J.1
Lugnier, C.2
Torres, A.I.3
Perez-Vizcaino, F.4
Zarzuelo, A.5
Tamargo, J.6
-
39
-
-
0023367869
-
Inhibition of cAMP phosphodiesterase by some phototherapeutic agents
-
Bovalini L., Lusini P., Simoni S., Vedaldi D., Andreassi L., Dall'Acqua F.,, et al. Inhibition of cAMP phosphodiesterase by some phototherapeutic agents. Z Naturforsch C 1987 ; 42 (7-8). 1009-1010.
-
(1987)
Z Naturforsch
, vol.42
, Issue.7-8
, pp. 1009-1010
-
-
Bovalini, L.1
Lusini, P.2
Simoni, S.3
Vedaldi, D.4
Andreassi, L.5
Dall'Acqua, F.6
-
40
-
-
4444368819
-
Imperatorin inhibits HIV-1 replication through an Sp1-dependent pathway
-
Sancho R., Marquez N., Gomez-Gonzalo M., Calzado MA, Bettoni G., Coiras MT,, et al. Imperatorin inhibits HIV-1 replication through an Sp1-dependent pathway. J Biol Chem 2004 ; 279 (36). 37349-37359.
-
(2004)
J Biol Chem
, vol.279
, Issue.36
, pp. 37349-37359
-
-
Sancho, R.1
Marquez, N.2
Gomez-Gonzalo, M.3
Ma, C.4
Bettoni, G.5
Coiras, M.T.6
-
41
-
-
0029127229
-
Rolipram, a specific type IV phosphodiesterase inhibitor, is a potent inhibitor of HIV-1 replication
-
Angel JB, Saget BM, Walsh SP, Greten TF, Dinarello CA, Skolnik PR,, et al. Rolipram, a specific type IV phosphodiesterase inhibitor, is a potent inhibitor of HIV-1 replication. AIDS 1995 ; 9 (10). 1137-1144.
-
(1995)
AIDS
, vol.9
, Issue.10
, pp. 1137-1144
-
-
Angel, J.B.1
Saget, B.M.2
Walsh, S.P.3
Greten, T.F.4
Dinarello, C.A.5
Skolnik, P.R.6
|