Stereoselective synthesis of the C33-C44 fragment of palau'amide

Tetrahedron Letters

Volumn 49, Issue 5, 2008, Pages 786-789

  Mohapatra, Debendra K ^a   Nayak, Sabita ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

Cytotoxic; Luche's stereoselective reduction; Palau'amide; Sharpless asymmetric epoxidation; Stereoselective

Indexed keywords

DEPSIPEPTIDE; PALAU'AMIDE; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; BIOLOGICAL ACTIVITY; CHEMICAL REACTION; CHEMICAL STRUCTURE; EPOXIDATION; GRIGNARD REACTION; OXIDATION; STEREOCHEMISTRY;

EID: 37649013007     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.11.200     Document Type: Article

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5. Enantiomeric purity of the product formed was verified by HPLC analysis. HPLC conditions: column, CHIRALCEL [OJ-H (5 μm spherical) 250 × 4.6 mm]; mobile phase, IPA-petroleum ether (1:9); flow rate, 0.5 mL/min; UV detection at 220 nm.
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