Synthesis and bioactivity of novel phthalimide derivatives

Chinese Chemical Letters

Volumn 19, Issue 1, 2008, Pages 26-28

  Wang, Tao ^a   Zhang, Yi Hua ^a   Ji, Hui ^a   Chen, Yan Ping ^a   Peng, Si Xun ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Antiangiogenic activity; Antitumor activity; NO ASA; Thalidomide

Indexed keywords

EID: 37549069905     PISSN: 10018417     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cclet.2007.10.049     Document Type: Article

References (14)

1. Liekens S., Clercq E.D., and Neyts J. Biochem. Pharmacol. 61 2 (2001) 253
2. Sano H., Noguchi T., and Miyajima A. Bioorg. Med. Chem. Lett. 16 11 (2006) 3068
3. Amato D., loughman M., Flynn E., et al. Proc. Natl. Acad. Sci. U.S.A. 91 12 (1994) 4082
4. Steve K., David T., Stirling I., et al. Drug Discov. Today 10 (2005) 107
5. Richardson P., Mitsiades C., and Hideshima T. Best Practice Res. Clin. Haematol. 18 4 (2005) 619
6. Shah J.H., Swartz G., Papathanassiu A., et al. J. Med. Chem. 42 16 (1999) 3014
7. Hashimoto Y. Bioorg. Med. Chem. 10 3 (2002) 61
8. Noguchi T., Nagasawaa K., and Hashimoto Y. Bioorg. Med. Chem. Lett. 12 7 (2002) 1043
9. Lima L.M., Machado A.L., and Barreiro E.J. Bioorg. Med. Chem. 10 9 (2002) 3067
10. Shinji C., Nakamura T., and Maeda S. Bioorg. Med. Chem. Lett. 15 15 (2005) 4427
11. Chiroli V., Benedini F., Ongini E., et al. Eur. J. Med. Chem. 38 (2003) 441
12. Ng S.S.W., Tschow M.G., and Weiss M. Cancer Res. 63 12 (2003) 3189
13. Mosmann T. J. Immunol. Methods 65 (1983) 55
14. 3, δ ppm): 8.00 (m, 2H), 7.88 (m, 2H), 7.84 (m, 2H), 7.62 (m, 2H), 4.28 (t, 2H, J = 6.0 Hz), 4.56 (t, 2H, J = 6.0 Hz), 2.02-2.09 (m, 4H).