In vitro and in vivo interaction of synthetic peroxide RBx11160 (OZ277) with piperaquine in Plasmodium models

Experimental Parasitology

Volumn 115, Issue 3, 2007, Pages 296-300

  Snyder, Christopher ^a   Chollet, Jacques ^a   Santo Tomas, Josefina ^a   Scheurer, Christian ^a   Wittlin, Sergio ^a  

^a SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

50 inhibitory concentration; 90 effective dose; ACT; artemisinin based combination therapy; counts per minute; cpm; ED90; FIC; fractional inhibitory concentrations; IC50; In vitro and in vivo combinations; Malaria; Mean FICs; Mean sums of fractional inhibitory concentrations; Medicines for Malaria Venture; MMV; Peroxide; Piperaquine; Plasmodium berghei; Plasmodium falciparum; RBx11160 (OZ277)

Indexed keywords

ANTIMALARIAL AGENT; ARTEMETHER; ATOVAQUONE; PIPERAQUINE; PROGUANIL; PYRIMETHAMINE; RBX 11160; SULFADOXINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; MALARIA; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIMALARIALS; ARTEMISININS; ATOVAQUONE; DISEASE MODELS, ANIMAL; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; ERYTHROCYTES; FEMALE; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; MALARIA; MICE; PARASITEMIA; PARASITIC SENSITIVITY TESTS; PEROXIDES; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PYRIMETHAMINE; QUINOLINES; SPIRO COMPOUNDS;

MINUTE VIRUS OF MICE; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM;

EID: 37549066714     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2006.09.016     Document Type: Article

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