Analgesic synergy between topical opioids and topical non-steroidal anti-inflammatory drugs in the mouse model of thermal pain

European Journal of Pharmacology

Volumn 579, Issue 1-3, 2008, Pages 126-133

  Kolesnikov, Yuri ^a   Sõritsa, Denis ^a  

^a UNIVERSITY OF TARTU   (Estonia)

Author keywords

Analgesia; Diclofenac; Ibuprofen; Lauric acid; Synergy; Topical opioid

Indexed keywords

DICLOFENAC; HYDROCODONE; IBUPROFEN; LAURIC ACID; LIDOCAINE; METHADONE; MORPHINE; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PROPYLENE GLYCOL;

ANALGESIA; ANIMAL EXPERIMENT; ARTICLE; DRUG ACTIVITY; DRUG EFFECT; DRUG PENETRATION; DRUG POTENTIATION; MALE; MOUSE; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; SKIN PERMEABILITY; TAIL FLICK TEST;

ADMINISTRATION, CUTANEOUS; ANALGESICS, OPIOID; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; EXCIPIENTS; HEAT; LAURIC ACIDS; MALE; MICE; MICE, INBRED ICR; PAIN; PAIN MEASUREMENT; PERMEABILITY; PROPYLENE GLYCOL; TAIL;

EID: 37549053340     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.10.014     Document Type: Article

References (35)

1. Ambrose A. Retrospective study of the effect of postoperative indomethacin rectal suppositories on the need for narcotic analgesia in patients who had a cesarean delivery while they were under regional anesthesia. Am. J. Obstet. Gynecol. 184 (2001) 1544-1549
2. Burian M., Tegeder M., Seegel T., and Geisslinger C. Peripheral and central antihyperalgesic effects of diclofenac in a model of human inflammatory pain. Clin. Pharmacol. Ther. 4 (2003) 113-120
3. Carney L.A., Nicolette M.H., Ratner A., Minerd T.J., and Baesl M. Ketorolac reduces postoperative narcotic requirements. J. Pediatr. Surg. 36 (2001) 766-768
4. Cataldo A.J., Senagore M., and Kilbride M. Ketorolac and patient-controlled analgesia in the treatment of postoperative pain. Surg. Gynecol. Obstet. 176 (1993) 435-438
5. Commens C.A. Topical propylene glycol and hyperosmolality. Br. J. Dermatol. 122 (1990) 77-80
6. Deciga-Campos M., Lopez U., Reva M., and Lopez-Munoz F. Enhancement of antinociception by co-administration of an opioid drug (morphine) and a preferential cyclooxygenase-2 inhibitor (rofecoxib) in rats. Eur. J. Pharmacol. 460 (2003) 99-107
7. Fletcher D., Benoist J., Gautron M., and Guilbaud G. Isobolographic analysis of interactions between intravenous morphine, propacetamol, and diclofenac in carrageenin-injected rats. Anesthesiology 87 (1997) 317-326
8. Funke A., Schiller R., Motzkus H., Gunter C., Muller R., and Lipp R. Transdermal delivery of highly lipophilic drugs: in vitro fluxes of antiestrogens, permeation enhancers, and solvents from liquid formulations. Pharm. Res. 19 (2002) 661-668
9. Hadgraft J. Recent developments in topical and transdermal delivery. Eur. J. Drug Metab. Pharmacokinet. 21 (1996) 165-173
10. Hadgraft J. Dermal and transdermal drug design. Int. J. Pharm. Med. 13 (1999) 155-158
11. Galer B.S., Rowbotham M., Perande R.J., Devers A., and Friedman E. Topical diclofenac patch relieves minor sports injury pain: results of a multicenter controlled clinical trials. J. Pain Symptom Manage. 19 (2000) 287-294
12. Gallagher R., Arndt D., and Hunt K. Analgesic effects of topical methadone. Clin. J. Pain 21 (2005) 190-192
13. Kolesnikov Y., Jain S., Wilson R., and Pasternak G. Topical opioids in mice: analgesia and reversal of tolerance by a topical N-methyl-d-aspartate antagonist. J. Pharmacol. Exp. Ther. 290 (1999) 247-252
14. Kolesnikov Y., Chereshnev I., and Pasternak G. Analgesic synergy between topical lidocaine and topical opioids. J. Pharmacol. Exp. Ther. 295 (2000) 546-551
15. Kolesnikov Y., Wilson R., and Pasternak G. Synergistic analgesic interactions between hydrocodone and ibuprofen. Anesth. Analg. 97 (2003) 1721-1723
16. Kolesnikov Y., Cristea M., Oksman G., Torosjan A., and Wilson R. Evaluation of the tail formalin test in mice as new model to assess local analgesic effects. Brain Res. 1029 (2004) 217-223
17. Kroin J.S., Buvanendran A., McCarthy R.J., Hemmati H., and Tuman K.J. Cyclooxygenase-2 inhibition potentiates morphine antinociception at the spinal level in a postoperative pain model. Reg. Anesth. Pain Med. 27 (2002) 451-455
18. Lashbrook J.M., Ossipova M.H., Hunter J.M., Raffia R.B., Tallarida R.J., and Porreca F. Synergistic antiallodynic effects of spinal morphine with ketorolac and selective COX1- and COX2-inhibitors in nerve-injured rats. Pain 82 (1999) 65-72
19. + channel pathway in the antinociceptive action of ketorolac. Eur. J. Pharmacol. 426 (2001) 41-46
20. Maves T.J., Pechman P.S., Meller S.T., and Gebhart G.F. Ketorolac potentiates morphine antinociception during visceral nociception in the rat. Anesthesiology 80 (1994) 1094-1101
21. O'Hanlon J., McCleane G., and Muldoon T. Preoperative application of piroxicam gel compared to a local anaesthetic field block for postoperative analgesia. Acta Anaesthesiol. Scand. 40 715 (1996) 718
22. Oh H., Oh K., and Kim C.K. Effects of vehicles and enhancers on transdermal delivery of melatonin. Int. J. Pharm. 212 (2001) 63-71
23. Ortiz M.I., Soto V.G., and Hernandez G.C. The NO-cGMP-K channels pathway participates in the antinociceptive effects of diclofenac, but not of indomethacin. Pharmacol. Biochem. Behav. 76 (2003) 187-195
24. Papworth J., Colville-Nash P., Alam C., Seed M., and Willoughby S. The depletion of substance P by diclofenac in the mouse. Eur. J. Pharmacol. 325 (1999) 1-2
25. Payne, and Pasternak. Pharmacology of pain treatment. In: Johnston, et al. (Ed). Contemporary Neurology Series: Scientific Basis of Neurologic Drug Therapy (1992), Davis, Philadelphia 268-301
26. Raffa R.B. Pharmacology of oral combination analgesics: rational therapy for pain. J. Clin. Pharm. Ther. 26 (2001) 257-264
27. Southall M.D., and Vasko M.R. Prostaglandin receptor subtypes, EP3C and EP4, mediate the prostaglandin E2-induced cAMP production and sensitization of sensory neurons. J. Biol. Chem. 276 (2001) 16083-16091
28. Southall M.D., Li T., Charibova L.S., Pei Y., Nicol G.D., and Travers J.B. Activation of epidermal vaniloid receptor-1 induces release of proinflammatory mediators in human kerotinocytes. J. Pharmacol. Exp. Ther. 304 (2003) 217-222
29. Suh H., Jun H.W., Dzimanski M.T., and Lu G.W. Pharmacokinetic and local tissue disposition studies of naproxen following topical and systemic administration in dogs and rats. Biopharm. Drug Dispos. 18 (1997) 623-633
30. Tonussi C.R., and Ferreira S.H. Mechanism of diclofenac analgesia: direct blockade of inflammatory sensitization. Eur. J. Pharmacol. 251 (1994) 173-179
31. Twillman R., Long M., and Cathers T. Treatment of painful skin ulcers with topical opioids. J. Pain Symptom Manage. 17 (1999) 288-292
32. Vaile J.H., and Davis P. Topical NSAIDs for musculoskeletal conditions: a review of the literature. Drugs 56 (1998) 783-799
33. Warner T.D., and Mitchel J.A. Cyclooxygenase: new forms, new inhibitors, and lessons from clinic. FASEB 18 (2004) 790-803
34. Wideman G.I., Keffer M., Morris E., Doyle R.T., Jiang J.G., and Beaver W.T. Analgesic efficacy of a combination of hydrocodone with ibuprofen in postoperative pain. Clin. Pharmacol. Ther. 65 (1999) 66-76
35. Zelcer Sh., Kolesnikov Y., and Pasternak G. Selective synergy between NSAID and Opiates. Brain Res. 1040 (2005) 151-156