Inhibition of NADPH oxidase by apocynin inhibits lipopolysaccharide (LPS) induced up-regulation of arginase in rat alveolar macrophages

European Journal of Pharmacology

Volumn 579, Issue 1-3, 2008, Pages 403-410

  Matthiesen, Sonja ^a   Lindemann, Dirk ^a   Warnken, Mareille ^a   Juergens, Uwe R ^b   Racké, Kurt ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

Airway inflammation; Alveolar macrophages; Apocynin; Arginase; iNOS; Lipopolysacharides; NADPH oxidase; Reactive oxygen species

Indexed keywords

APOCYNIN; ARGINASE; ARGINASE 1; ARGINASE 2; FORMAZAN; HYDROGEN PEROXIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOENZYME; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRITE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TETRAZOLIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASSAY; BIOACCUMULATION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; LUNG ALVEOLUS MACROPHAGE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; RNA ANALYSIS; RNA STABILITY; UPREGULATION;

ACETOPHENONES; ANIMALS; ARGINASE; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIPOPOLYSACCHARIDES; MACROPHAGES, ALVEOLAR; MALE; NADPH OXIDASE; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SUPEROXIDES; UP-REGULATION;

EID: 37549049832     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.10.043     Document Type: Article

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