-
1
-
-
33845233708
-
On the pharmacological action of some phthaleins and their derivatives, with especial reference to their behavior as purgatives
-
Abel JJ and Rowntree LG (1909) On the pharmacological action of some phthaleins and their derivatives, with especial reference to their behavior as purgatives. J Pharmacol Exp Ther 1:231-264.
-
(1909)
J Pharmacol Exp Ther
, vol.1
, pp. 231-264
-
-
Abel, J.J.1
Rowntree, L.G.2
-
2
-
-
37549015778
-
The biological liberation of morphine from codeine in the rat
-
Adler TK and Shaw FH (1952) The biological liberation of morphine from codeine in the rat. J Pharmacol Exp Ther 104:1-10.
-
(1952)
J Pharmacol Exp Ther
, vol.104
, pp. 1-10
-
-
Adler, T.K.1
Shaw, F.H.2
-
3
-
-
0001502761
-
Studies on sympathomimetic amines. II. The biotransformation and physiological disposition of d-amphetamine, d-p-hydroxyamphetamine and d-methamphetamine
-
Axelrod J (1954) Studies on sympathomimetic amines. II. The biotransformation and physiological disposition of d-amphetamine, d-p-hydroxyamphetamine and d-methamphetamine. J Pharmacol Exp Ther 110:315-326.
-
(1954)
J Pharmacol Exp Ther
, vol.110
, pp. 315-326
-
-
Axelrod, J.1
-
4
-
-
37549019462
-
The enzymatic conversion of codeine to morphine
-
Axelrod J (1955a) The enzymatic conversion of codeine to morphine. J Pharmacol Exp Ther 115:259-267.
-
(1955)
J Pharmacol Exp Ther
, vol.115
, pp. 259-267
-
-
Axelrod, J.1
-
5
-
-
0001232764
-
The enzymatic demethylation of ephedrine
-
Axelrod J (1955b) The enzymatic demethylation of ephedrine. J Pharmacol Exp Ther 114:430-438.
-
(1955)
J Pharmacol Exp Ther
, vol.114
, pp. 430-438
-
-
Axelrod, J.1
-
6
-
-
84930873267
-
Mechanism of the potentiating action of β-diethylaminoethyldiphenylpropylacetate
-
Axelrod J, Reichenthal J, and Brodie BB (1954) Mechanism of the potentiating action of β-diethylaminoethyldiphenylpropylacetate. J Pharmacol Exp Ther 112:49-54.
-
(1954)
J Pharmacol Exp Ther
, vol.112
, pp. 49-54
-
-
Axelrod, J.1
Reichenthal, J.2
Brodie, B.B.3
-
7
-
-
0022366179
-
History of drug metabolism: The first half of the 20th Century
-
Bachmann C and Bickel MH (1985) History of drug metabolism: the first half of the 20th Century. Drug Metab Rev 16:185-253.
-
(1985)
Drug Metab Rev
, vol.16
, pp. 185-253
-
-
Bachmann, C.1
Bickel, M.H.2
-
8
-
-
37549010864
-
The reduction of neoprontosil by tissues in vitro
-
Bernheim F (1941) The reduction of neoprontosil by tissues in vitro. J Pharmacol Exp Ther 71:344-348.
-
(1941)
J Pharmacol Exp Ther
, vol.71
, pp. 344-348
-
-
Bernheim, F.1
-
9
-
-
37549053044
-
The oxidation in vitro of morphine by rat liver slices
-
Bernheim F and Bernheim M (1944) The oxidation in vitro of morphine by rat liver slices. J Pharmacol Exp Ther 81:374-377.
-
(1944)
J Pharmacol Exp Ther
, vol.81
, pp. 374-377
-
-
Bernheim, F.1
Bernheim, M.2
-
10
-
-
37549007730
-
Note on the in vitro inactivation of morphine by liver
-
Bernheim F and Bernheim MLC (1945a) Note on the in vitro inactivation of morphine by liver. J Pharmacol Exp Ther 83:85.
-
(1945)
J Pharmacol Exp Ther
, vol.83
, pp. 85
-
-
Bernheim, F.1
Bernheim, M.L.C.2
-
12
-
-
37549010863
-
The conjugation in vitro of phenol by guinea pig liver
-
Bernheim F and Bernheim MLC (1943) The conjugation in vitro of phenol by guinea pig liver. J Pharmacol Exp Ther 78:394-399.
-
(1943)
J Pharmacol Exp Ther
, vol.78
, pp. 394-399
-
-
Bernheim, F.1
Bernheim, M.L.C.2
-
13
-
-
0029768718
-
Eli K. Marshall, Jr. (1889 -1966): From biochemistry and physiology to pharmacology and pharmacokinetics
-
Bickel MH (1996) Eli K. Marshall, Jr. (1889 -1966): from biochemistry and physiology to pharmacology and pharmacokinetics. Drug Metab Rev 28:311-344.
-
(1996)
Drug Metab Rev
, vol.28
, pp. 311-344
-
-
Bickel, M.H.1
-
14
-
-
0000139091
-
A new coupling component for sulfanilamide determination
-
Bratton AC and Marshall EKJ (1939) A new coupling component for sulfanilamide determination. J Biol Chem 128:537-550.
-
(1939)
J Biol Chem
, vol.128
, pp. 537-550
-
-
Bratton, A.C.1
Marshall, E.K.J.2
-
15
-
-
0002616596
-
The estimation of acetanilide and its metabolic products, aniline, N-acetylp-aminophenol and p-aminophenol (free and total conjugated) in biological fluids and tissues
-
Brodie BB and Axelrod J (1948a) The estimation of acetanilide and its metabolic products, aniline, N-acetylp-aminophenol and p-aminophenol (free and total conjugated) in biological fluids and tissues. J Pharmacol Exp Ther 94:22-28.
-
(1948)
J Pharmacol Exp Ther
, vol.94
, pp. 22-28
-
-
Brodie, B.B.1
Axelrod, J.2
-
17
-
-
0000948052
-
Detoxication of drugs and other foreign compounds by liver microsomes
-
Brodie BB, Axelrod J, Cooper JR, Gaudette L, La Du B, Mitoma C, and Udenfriend S (1955) Detoxication of drugs and other foreign compounds by liver microsomes. Science 121:603-604.
-
(1955)
Science
, vol.121
, pp. 603-604
-
-
Brodie, B.B.1
Axelrod, J.2
Cooper, J.R.3
Gaudette, L.4
La Du, B.5
Mitoma, C.6
Udenfriend, S.7
-
18
-
-
0011218338
-
The estimation of basic organic compounds in biological material. I. General principles
-
Brodie BB, Udenfriend S, and Baer JE (1947) The estimation of basic organic compounds in biological material. I. General principles. J Biol Chem 168:299-309.
-
(1947)
J Biol Chem
, vol.168
, pp. 299-309
-
-
Brodie, B.B.1
Udenfriend, S.2
Baer, J.E.3
-
19
-
-
37549012325
-
-
Brodie BB and Udenfriend S, with the assistance of Baer JE, Chenkin T, and Dill W (1945) The estimation of basic organic compounds and a technique for the appraisal of specificity, application to the cinchona alkaloids. J Biol Chem 158:705-714.
-
Brodie BB and Udenfriend S, with the assistance of Baer JE, Chenkin T, and Dill W (1945) The estimation of basic organic compounds and a technique for the appraisal of specificity, application to the cinchona alkaloids. J Biol Chem 158:705-714.
-
-
-
-
20
-
-
0001244692
-
The metabolic hydroxylation of phenobarbital
-
Butler T (1956) The metabolic hydroxylation of phenobarbital. J Pharmacol Exp Ther 116:326-336.
-
(1956)
J Pharmacol Exp Ther
, vol.116
, pp. 326-336
-
-
Butler, T.1
-
21
-
-
0015212937
-
Some historical reflections on drug metabolism
-
Butler T (1971) Some historical reflections on drug metabolism. Ann N Y Acad Sci 179:502-507.
-
(1971)
Ann N Y Acad Sci
, vol.179
, pp. 502-507
-
-
Butler, T.1
-
22
-
-
0002541649
-
The metabolic fate of chloral hydrate
-
Butler TC (1948) The metabolic fate of chloral hydrate. J Pharmacol Exp Ther 92:49-58.
-
(1948)
J Pharmacol Exp Ther
, vol.92
, pp. 49-58
-
-
Butler, T.C.1
-
23
-
-
0006108161
-
Quantitative studies of the demethylation of trimethadione (tridione)
-
Butler TC (1953) Quantitative studies of the demethylation of trimethadione (tridione). J Pharmacol Exp Ther 108:11-17.
-
(1953)
J Pharmacol Exp Ther
, vol.108
, pp. 11-17
-
-
Butler, T.C.1
-
24
-
-
0003139602
-
The metabolic conversion of 5,5-diphenyl hydantoin to 5-(p-hydroxyphenyl)-5-phenyl hydantoin
-
Butler TC (1957) The metabolic conversion of 5,5-diphenyl hydantoin to 5-(p-hydroxyphenyl)-5-phenyl hydantoin. J Pharmacol Exp Ther 119:1-11.
-
(1957)
J Pharmacol Exp Ther
, vol.119
, pp. 1-11
-
-
Butler, T.C.1
-
25
-
-
0001627764
-
Phenobarbital: Studies of elimination, accumulation, tolerance, and dosage schedules
-
Butler TC, Mahaffee C, and Waddell WJ (1954) Phenobarbital: studies of elimination, accumulation, tolerance, and dosage schedules. J Pharmacol Exp Ther 111:425-435.
-
(1954)
J Pharmacol Exp Ther
, vol.111
, pp. 425-435
-
-
Butler, T.C.1
Mahaffee, C.2
Waddell, W.J.3
-
26
-
-
37549033262
-
The American Society for Pharmacology and Experimental Therapeutics, Incorporated: The First Sixty Years, 1908-1969
-
Chen K, ed , Washington, DC
-
Chen K, ed (1969) The American Society for Pharmacology and Experimental Therapeutics, Incorporated: The First Sixty Years, 1908-1969, Judd & Detweiler, Washington, DC.
-
(1969)
Judd & Detweiler
-
-
-
27
-
-
0004481854
-
Treatment with prontosil of puerperal infections due to hemolytic streptococci
-
Colebrook L and Kenny M (1936) Treatment with prontosil of puerperal infections due to hemolytic streptococci. Lancet 2:1319 -1322.
-
(1936)
Lancet
, vol.2
, pp. 1319-1322
-
-
Colebrook, L.1
Kenny, M.2
-
28
-
-
0017647042
-
History of drug metabolism. Discoveries of the major pathways in the 19th century
-
Conti A and Bickel MH (1977) History of drug metabolism. Discoveries of the major pathways in the 19th century. Drug Metab Rev 6:1-50.
-
(1977)
Drug Metab Rev
, vol.6
, pp. 1-50
-
-
Conti, A.1
Bickel, M.H.2
-
29
-
-
37549020861
-
The effect of β-diethylaminoethyldiphenylpropylacetate hydrochloride on the action of a series of barbiturates and C.N.S. depressants
-
Cook L, Macko E, and Fellows EJ (1954a) The effect of β-diethylaminoethyldiphenylpropylacetate hydrochloride on the action of a series of barbiturates and C.N.S. depressants. J Pharmacol Exp Ther 112:382-386.
-
(1954)
J Pharmacol Exp Ther
, vol.112
, pp. 382-386
-
-
Cook, L.1
Macko, E.2
Fellows, E.J.3
-
30
-
-
37549041486
-
The effect of β-diethylaminoethyldiphenylpropylacetate hydrochloride (SKF No. 525a) on hexobarbital
-
Cook L, Toner JJ, and Fellows EJ (1954b) The effect of β-diethylaminoethyldiphenylpropylacetate hydrochloride (SKF No. 525a) on hexobarbital. J Pharmacol Exp Ther 111:131-141.
-
(1954)
J Pharmacol Exp Ther
, vol.111
, pp. 131-141
-
-
Cook, L.1
Toner, J.J.2
Fellows, E.J.3
-
31
-
-
0009514720
-
Inhibitory effects of β-diethylaminoethyldiphenylpropylacetate on a variety of drug metabolic pathways in vitro
-
Cooper JR, Axelrod J, and Brodie BB (1954) Inhibitory effects of β-diethylaminoethyldiphenylpropylacetate on a variety of drug metabolic pathways in vitro. J Pharmacol Exp Ther 112:55-63.
-
(1954)
J Pharmacol Exp Ther
, vol.112
, pp. 55-63
-
-
Cooper, J.R.1
Axelrod, J.2
Brodie, B.B.3
-
32
-
-
0000585001
-
The enzymatic metabolism of hexobarbital (evipal)
-
Cooper JR and Brodie BB (1955) The enzymatic metabolism of hexobarbital (evipal). J Pharmacol Exp Ther 114:409-417.
-
(1955)
J Pharmacol Exp Ther
, vol.114
, pp. 409-417
-
-
Cooper, J.R.1
Brodie, B.B.2
-
34
-
-
0001366010
-
Identification of small amounts of organic compounds by distribution studies. II. Separation by counter-current distribution
-
Craig LC (1944) Identification of small amounts of organic compounds by distribution studies. II. Separation by counter-current distribution. J Biol Chem 155:519-534.
-
(1944)
J Biol Chem
, vol.155
, pp. 519-534
-
-
Craig, L.C.1
-
36
-
-
37549009693
-
The distribution of radioactivity in rats after administration of C14-labeled methadone
-
Elliott HW, Chang FNH, Abdou IA, and Anderson HH (1949) The distribution of radioactivity in rats after administration of C14-labeled methadone. J Pharmacol Exp Ther 95:494-501.
-
(1949)
J Pharmacol Exp Ther
, vol.95
, pp. 494-501
-
-
Elliott, H.W.1
Chang, F.N.H.2
Abdou, I.A.3
Anderson, H.H.4
-
37
-
-
7544230968
-
A tribute to James Robert Gillette
-
Estabrook RW (2003) A tribute to James Robert Gillette. Drug Metab Dispos 31:1459-1460.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 1459-1460
-
-
Estabrook, R.W.1
-
38
-
-
0022002912
-
Trypanothione: A novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids
-
Fairlamb AH, Blackburn P, Ulrich P, Chait BT, and Cerami A (1985) Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids. Science 227:1485-1487.
-
(1985)
Science
, vol.227
, pp. 1485-1487
-
-
Fairlamb, A.H.1
Blackburn, P.2
Ulrich, P.3
Chait, B.T.4
Cerami, A.5
-
39
-
-
0001718982
-
Studies on pig liver microsomes. I. Enzymic and pigment composition of different microsomal fractions
-
Garfinkel D (1958) Studies on pig liver microsomes. I. Enzymic and pigment composition of different microsomal fractions. Arch Biochem Biophys 77:493-509.
-
(1958)
Arch Biochem Biophys
, vol.77
, pp. 493-509
-
-
Garfinkel, D.1
-
40
-
-
0000701892
-
The oxidation of drugs by liver microsomes: On the role of TPNH and oxygen
-
Gillette JH, Brodie BB, and La Du BN (1957) The oxidation of drugs by liver microsomes: on the role of TPNH and oxygen. J Pharmacol Exp Ther 119:532-540.
-
(1957)
J Pharmacol Exp Ther
, vol.119
, pp. 532-540
-
-
Gillette, J.H.1
Brodie, B.B.2
La Du, B.N.3
-
41
-
-
37549019074
-
The metabolic fate of acetanilid and other aniline derivatives: I. Major metabolites of acetanilid appearing in the urine
-
Greenberg LA and Lester D (1946) The metabolic fate of acetanilid and other aniline derivatives: I. Major metabolites of acetanilid appearing in the urine. J Pharmacol Exp Ther 88:87-98.
-
(1946)
J Pharmacol Exp Ther
, vol.88
, pp. 87-98
-
-
Greenberg, L.A.1
Lester, D.2
-
44
-
-
0034000483
-
History of drug metabolism research in Japan
-
Kato R and Yamazoe Y (2000) History of drug metabolism research in Japan. Drug Metab Rev 32:45-79.
-
(2000)
Drug Metab Rev
, vol.32
, pp. 45-79
-
-
Kato, R.1
Yamazoe, Y.2
-
45
-
-
0001202995
-
Pigments of rat liver microsomes
-
Klingenberg M (1958) Pigments of rat liver microsomes. Arch Biochem Biophys 75:376-386.
-
(1958)
Arch Biochem Biophys
, vol.75
, pp. 376-386
-
-
Klingenberg, M.1
-
46
-
-
37549047356
-
Some aspects of the metabolism of codeine in the rat
-
Latham ME and Elliott HW (1951) Some aspects of the metabolism of codeine in the rat. J Pharmacol Exp Ther 101:259-267.
-
(1951)
J Pharmacol Exp Ther
, vol.101
, pp. 259-267
-
-
Latham, M.E.1
Elliott, H.W.2
-
47
-
-
84984817983
-
The metabolic fate of acetanilid and other aniline derivatives: II. Major metabolites of acetanilid appearing in the blood
-
Lester D, Greenberg LA, and Carroll RP (1947) The metabolic fate of acetanilid and other aniline derivatives: II. Major metabolites of acetanilid appearing in the blood. J Pharmacol Exp Ther 90:68-75.
-
(1947)
J Pharmacol Exp Ther
, vol.90
, pp. 68-75
-
-
Lester, D.1
Greenberg, L.A.2
Carroll, R.P.3
-
49
-
-
0035127204
-
A life in science: Biochemist-nutritionist-forensic toxicologist-pharmacologist
-
Mannering GJ (2001) A life in science: biochemist-nutritionist-forensic toxicologist-pharmacologist. Drug Metab Rev 33:81-116.
-
(2001)
Drug Metab Rev
, vol.33
, pp. 81-116
-
-
Mannering, G.J.1
-
52
-
-
0343436585
-
The metabolism of barbiturates
-
Maynert EW and Dyke HB (1949) The metabolism of barbiturates. Pharmacol Rev 1:217-242.
-
(1949)
Pharmacol Rev
, vol.1
, pp. 217-242
-
-
Maynert, E.W.1
Dyke, H.B.2
-
54
-
-
0000402728
-
Observations on the chronic toxicities of propylene glycol, ethylene glycol, diethylene glycol, ethylene glycol mono-ethyl-ether, and diethylene glycol mono-ethyl-ether
-
Morris HJ, Nelson AA, and Calvrey HO (1942) Observations on the chronic toxicities of propylene glycol, ethylene glycol, diethylene glycol, ethylene glycol mono-ethyl-ether, and diethylene glycol mono-ethyl-ether. J Pharmacol Exp Ther 74:266-273.
-
(1942)
J Pharmacol Exp Ther
, vol.74
, pp. 266-273
-
-
Morris, H.J.1
Nelson, A.A.2
Calvrey, H.O.3
-
55
-
-
0035000044
-
Xenobiotic metabolism: A look from the past to the future
-
Murphy PJ (2001) Xenobiotic metabolism: a look from the past to the future. Drug Metab Dispos 29:779-780.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 779-780
-
-
Murphy, P.J.1
-
56
-
-
0000600087
-
Relationship of the chemical structure of morphine derivatives to their urinary excretion in free and bound forms
-
Oberst FW (1941) Relationship of the chemical structure of morphine derivatives to their urinary excretion in free and bound forms. J Pharmacol Exp Ther 73:401-404.
-
(1941)
J Pharmacol Exp Ther
, vol.73
, pp. 401-404
-
-
Oberst, F.W.1
-
58
-
-
0030825283
-
A history of drug metabolism in the United Kingdom
-
Parke D (1997) A history of drug metabolism in the United Kingdom. Drug Metab Rev 29:801-851.
-
(1997)
Drug Metab Rev
, vol.29
, pp. 801-851
-
-
Parke, D.1
-
59
-
-
0344238038
-
On the pharmacology of N1-para-chlorophenyl-N5-isopropylbiguanide (paludrine)
-
Schmidt LH, Hughes HB, and Smith CC (1947) On the pharmacology of N1-para-chlorophenyl-N5-isopropylbiguanide (paludrine). J Pharmacol Exp Ther 90:233-253.
-
(1947)
J Pharmacol Exp Ther
, vol.90
, pp. 233-253
-
-
Schmidt, L.H.1
Hughes, H.B.2
Smith, C.C.3
-
60
-
-
37549006548
-
-
Shannon JA, Earle DPJ, Brodie BB, Taggart JV, Berliner RW, and staff residents (1944) The pharmacological basis for the rational use of atabrine in the treatment of malaria. J Pharmacol Exp Ther 81:307-330.
-
Shannon JA, Earle DPJ, Brodie BB, Taggart JV, Berliner RW, and staff residents (1944) The pharmacological basis for the rational use of atabrine in the treatment of malaria. J Pharmacol Exp Ther 81:307-330.
-
-
-
-
61
-
-
37549019818
-
Metabolism of pentaquine in the Rhesus monkey
-
Smith CC (1956) Metabolism of pentaquine in the Rhesus monkey. J Pharmacol Exp Ther 116:67-76.
-
(1956)
J Pharmacol Exp Ther
, vol.116
, pp. 67-76
-
-
Smith, C.C.1
-
62
-
-
37549009692
-
Quantitative studies on the gastrointestinal absorption of drugs I. The inhibitory action of phenol on absorption
-
Sollmann T, Hanzlik PJ, and Pilcher JD (1910) Quantitative studies on the gastrointestinal absorption of drugs I. The inhibitory action of phenol on absorption. J Pharmacol Exp Ther 1:409-444.
-
(1910)
J Pharmacol Exp Ther
, vol.1
, pp. 409-444
-
-
Sollmann, T.1
Hanzlik, P.J.2
Pilcher, J.D.3
-
63
-
-
37549047355
-
Editor's note: Pharmacological Reviews in review
-
Stitzel R (1999) Editor's note: Pharmacological Reviews in review. Pharmacol Rev 51:1-6.
-
(1999)
Pharmacol Rev
, vol.51
, pp. 1-6
-
-
Stitzel, R.1
-
64
-
-
84960994883
-
The effect of β-diethylaminoethyldiphenylpropylacetate (SKF No. 525a) on the anticonvulsant properties of antiepileptic drugs
-
Swinyard EA, Madsen JA, and Goodman LS (1954) The effect of β-diethylaminoethyldiphenylpropylacetate (SKF No. 525a) on the anticonvulsant properties of antiepileptic drugs. J Pharmacol Exp Ther 111:54-63.
-
(1954)
J Pharmacol Exp Ther
, vol.111
, pp. 54-63
-
-
Swinyard, E.A.1
Madsen, J.A.2
Goodman, L.S.3
-
65
-
-
0001568182
-
Activity of p-aminophenylsulfamide in the experimental streptococcal infections of the mouse and rabbit
-
Trefouél J, Trefouél J, Nitti F, and Bovet D (1935) Activity of p-aminophenylsulfamide in the experimental streptococcal infections of the mouse and rabbit. C R Seances Soc Biol 120:756.
-
(1935)
C R Seances Soc Biol
, vol.120
, pp. 756
-
-
Trefouél, J.1
Trefouél, J.2
Nitti, F.3
Bovet, D.4
-
66
-
-
0009055040
-
On the specificity of the so-called arsenic receptor in the higher animals
-
Voegtlin C, Dyer HA, and Leonard CS (1925) On the specificity of the so-called arsenic receptor in the higher animals. J Pharmacol Exp Ther 25:297-307.
-
(1925)
J Pharmacol Exp Ther
, vol.25
, pp. 297-307
-
-
Voegtlin, C.1
Dyer, H.A.2
Leonard, C.S.3
-
67
-
-
0346498384
-
Quantitative studies in chemotherapy III. The oxidation of arsphenamine
-
Voegtlin C and Smith HW (1920) Quantitative studies in chemotherapy III. The oxidation of arsphenamine. J Pharmacol Exp Ther 16:199-217.
-
(1920)
J Pharmacol Exp Ther
, vol.16
, pp. 199-217
-
-
Voegtlin, C.1
Smith, H.W.2
|