Crystal structure of vibrionaceae Photobacterium sp. JT-ISH-224 α2,6-sialyltransferase in a ternary complex with donor product CMP and acceptor substrate lactose: Catalytic mechanism and substrate recognition

Glycobiology

Volumn 18, Issue 1, 2008, Pages 66-73

  Kakuta, Yoshimitsu ^a   Okino, Nozomu ^a   Kajiwara, Hitomi ^b   Ichikawa, Masako ^b   Takakura, Yoshimitsu ^b   Ito, Makoto ^b   Yamamoto, Takeshi ^b  

^a KYUSHU UNIVERSITY   (Japan)

^b JAPAN TOBACCO INC   (Japan)

Author keywords

2,6 sialyltransfease; Crystal structure; Substrate assisted catalytic mechanism; Vibrionaceae Photobacterium sp. JT ISH 224

Indexed keywords

ALPHA 2,6 SIALYLTRANSFERASE; ASPARTIC ACID; CYTIDINE PHOSPHATE; GLYCOSYLTRANSFERASE; HISTIDINE; HYDROGEN; LACTOSE; SIALYLTRANSFERASE; TERNARY COMPLEX FACTOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL STRAIN; CATALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; GENE MUTATION; HYDROGEN BOND; MOLECULAR RECOGNITION; MUTATIONAL ANALYSIS; NONHUMAN; PHOTOBACTERIUM; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN STRUCTURE; PROTEIN TRANSPORT; REACTION ANALYSIS; RESIDUE ANALYSIS; VIBRIONACEAE; X RAY CRYSTALLOGRAPHY;

BACTERIAL PROTEINS; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; CYTIDINE MONOPHOSPHATE; GLYCEROL; LACTOSE; MODELS, MOLECULAR; PHOTOBACTERIUM; RECOMBINANT PROTEINS; SIALYLTRANSFERASES; SUBSTRATE SPECIFICITY;

PHOTOBACTERIUM SP.; VIBRIONACEAE;

EID: 37549044252     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwm119     Document Type: Article

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