Imaging cadavers: Cold FLAIR and noninvasive brain thermometry using CSF diffusion

Magnetic Resonance in Medicine

Volumn 59, Issue 1, 2008, Pages 190-195

  Tofts, Paul S ^a,c   Jackson, Jonathan S ^a   Tozer, Daniel J ^a   Cercignani, Mara ^a   Keir, Geoffrey ^a   MacManus, David G ^a   Ridgway, Gerard R ^b   Ridha, Basil H ^a   Schmierer, Klaus ^a   Siddique, Durre ^a   Thornton, John S ^a   Wroe, Stephen J ^a   Fox, Nick C ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c BRIGHTON AND SUSSEX MEDICAL SCHOOL   (United Kingdom)

Author keywords

Cerebrospinal fluid; Diffusion; Postmortem tissue; Water

Indexed keywords

BRAIN; DIFFUSION; DIFFUSION IN LIQUIDS; THERMOCOUPLES; THERMOMETERS; WATER;

CEREBRO SPINAL FLUIDS; CORE TEMPERATURE; IN-VITRO; IN-VIVO; IN-VIVO IMAGING; LOWER TEMPERATURES; RESEARCH PURPOSE; THERMOCOUPLE MEASUREMENTS;

CEREBROSPINAL FLUID;

ARTICLE; BRAIN TEMPERATURE; CADAVER; CEREBROSPINAL FLUID ANALYSIS; COLD FLAIR IMAGING; CORE TEMPERATURE; DIAGNOSTIC IMAGING; DIAGNOSTIC VALUE; DIFFUSION COEFFICIENT; FLUID ATTENUATED INVERSION RECOVERY IMAGING; HUMAN; HUMAN TISSUE; IN VIVO STUDY; INVERSION TIME; LOW TEMPERATURE; TIME;

EID: 37549032811     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.21456     Document Type: Article

References (19)

1. Griffiths PD, Paley MN, Whitby EH. Post-mortem MRI as an adjunct to fetal or neonatal autopsy. Lancet 2005;365:1271-1273.
2. Geurts JJ, Bo L, Pouwels PJ, Castelijns JA, Polman CH, Barkhof F. Cortical lesions in multiple sclerosis: combined postmortem MR imaging and histopathology. AJNR Am J Neuroradiol 2005;26:572-577.
3. Schmierer K, Scaravilli F, Altmann DR, Barker GJ, Miller DH. Magnetization transfer ratio and myelin in postmortem multiple sclerosis brain. Ann Neurol 2004;56:407-415.
4. Mottershead JP, Schmierer K, Clemence M, Thornton JS, Scaravilli F, Barker GJ, Tofts PS, Newcombe J, Cuzner ML, Ordidge RJ, McDonald WI, Miller DH. High field MRI correlates of myelin content and axonal density in multiple sclerosis - a post-mortem study of the spinal cord. J Neurol 2003;250:1293-1301.
5. Hajnal JV, Bryant DJ, Kasuboski L, Pattany PM, De CB, Lewis PD, Pennock JM, Oatridge A, Young IR, Bydder GM. Use of fluid attenuated inversion recovery (FLAIR) pulse sequences in MRI of the brain. J Comput Assist Tomogr 1992;16:841-844.
6. Tofts PS, Tozer DJ, MacManus DG, Schmierer K, Fox NC. Imaging cadavers - 'cold brain' MRI effects and noninvasive diffusion thermometry of the CSF. IN: Proc 14th Annual Meeting ISMRM, Seattle. 2006; p 2096.
7. Mills R. Self-diffusion in normal and heavy water in the range 1-45°. J Phys Chem 1973;77:685-688.
8. Tofts PS, Lloyd D, Clark CA, Barker GJ, Parker GJ, McConville P, Baldock C, Pope JM. Test liquids for quantitative MRI measurements of self-diffusion coefficient in vivo. Magn Reson Med 2000;43:368-374.
9. Krynicki IC. Proton spin lattice relaxation in pure water between 0°C and 100°C. Physica 1966;32:167-178.
10. Tofts PS. QA: quality assurance, accuracy, precision and phantoms. In: Tofts P, editor. Quantitative MRI of the brain: measuring changes caused by disease. Chichester, UK: John Wiley & Sons. 2003; p 55-81.
11. Hindman JC, Svirmickas A, Wood M. Relaxation processes in water. A study of the proton spin-lattice relaxation time. J Chem Phys 1973;59: 1517-1522.
12. Simpson JH, Carr HY. Diffusion and nuclear spin relaxation in water. Phys Rev 1958;111:1201-1202.
13. Callaghan PT. Principles of nuclear magnetic resonance microscopy. Oxford: Clarendon Press; 1991.
14. Annet L, Duprez T, Grandin C, Dooms G, Collard A, Cosnard G. Apparent diffusion coefficient measurements within intracranial epidermoid cysts in six patients. Neuroradiology 2002;44:326-328.
15. Hakyemez B, Aksoy U, Yildiz H, Ergin N. Intracranial epidermoid cysts: diffusion-weighted, FLAIR and conventional MR findings. Eur J Radiol 2005;54:214-220.
16. Latour LL, Warach S. Cerebral spinal fluid contamination of the measurement of the apparent diffusion coefficient of water in acute stroke. Magn Reson Med 2002;48:478-486.
17. Grant R, Condon B, Moyns S, Patterson J, Hadley D, Teasdale G. Temporal physiochemical changes during in vitro relaxation time measurements: the cerebrospinal fluid. Magn Reson Med 1988;6:397-402.
18. Hopkins AL, Yeung HN, Bratton CB. Multiple field strength in vivo T1 and T2 for cerebrospinal fluid protons. Magn Reson Med 1986;3:303-311.
19. Zaharchuk G, Martin AJ, Rosenthal G, Manley GT, Dillon WP. Measurement of cerebrospinal fluid oxygen partial pressure in humans using MRI. Magn Reson Med 2005;54:113-121.