Sensory transduction and adaptation in inner and outer hair cells of the mouse auditory system

Journal of Neurophysiology

Volumn 98, Issue 6, 2007, Pages 3360-3369

  Stauffer, Eric A ^a,b   Holt, Jeffrey R ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUDITORY SYSTEM; CALCIUM TRANSPORT; COCHLEA; CONFOCAL LASER MICROSCOPY; CYTOARCHITECTURE; ELECTROPHYSIOLOGY; HAIR CELL; HEARING; MECHANOTRANSDUCTION; MOUSE; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; STEREOCILIUM;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; COCHLEA; DATA INTERPRETATION, STATISTICAL; ELECTROPHYSIOLOGY; HAIR CELLS, AUDITORY, INNER; HAIR CELLS, AUDITORY, OUTER; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; PHYSICAL STIMULATION; VESTIBULE, LABYRINTH;

EID: 37549027947     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00914.2007     Document Type: Article

References (23)

1. Beurg M, Evans MG, Hackney CM, Fettiplace R. A large-conductance calcium-selective mechanotransducer channel in mammalian cochlear hair cells. J Neurosci 26: 10992-11000, 2006.
2. Bozovic D, Hudspeth AJ. Hair-bundle movements elicited by transepithelial electrical stimulation of hair cells in the sacculus of the bullfrog. Proc Natl Acad Sci USA 100: 958-963, 2003.
3. Denk W, Holt JR, Shepherd GM, Corey DP. Calcium imaging of single stereocilia in hair cells: localization of transduction channels at both ends of tip links. Neuron 15: 1311-1321, 1995.
4. Eatock RA, Corey DP, Hudspeth AJ. Adaptation of mechanoelectrical transduction in hair cells of the bullfrog's sacculus. J Neurosci 7: 2821-2836, 1987.
5. Fettiplace R, Ricci AJ. Adaptation in auditory hair cells. Curr Opin Neurobiol 13: 446-451, 2003.
6. Géléoc GS, Lennan GW, Richardson GP, Kros CJ. A quantitative comparison of mechanoelectrical transduction in vestibular and auditory hair cells of neonatal mice. Proc Biol Sci 264: 611-621, 1997.
7. Hirono M, Denis CS, Richardson GP, Gillespie PG. Hair cells require phosphatidylinositol 4,5-bisphosphate for mechanical transduction and adaptation. Neuron 44: 309-320, 2004.
8. Holt JR, Corey DP, Eatock RA. Mechanoelectrical transduction and adaptation in hair cells of the mouse utricle, a low-frequency vestibular organ. J Neurosci 17: 8739-8748, 1997.
9. Holt JR, Gillespie SK, Provance DW, Shah K, Shokat KM, Corey DP, Mercer JA, Gillespie PG. A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells. Cell 108: 371-381, 2002.
10. Howard J, Hudspeth AJ. Compliance of the hair bundle associated with gating of mechanoelectrical transduction channels in the bullfrog's saccular hair cell. Neuron 1: 189-199, 1988.
11. Hudspeth AJ. How hearing happens. Neuron 19: 947-950, 1997.
12. Jacobs RA, Hudspeth AJ. Ultrastructural correlates of mechanoelectrical transduction in hair cells of the bullfrog's internal ear. Cold Spring Harb Symp Quant Biol 55: 547-561, 1990.
13. Kennedy HJ, Evans MG, Crawford AC, Fettiplace R. Fast adaptation of mechanoelectrical transducer channels in mammalian cochlear hair cells. Nat Neurosci 6: 832-836, 2003.
14. Kozlov AS, Risler T, Hudspeth AJ. Coherent motion of stereocilia assures the concerted gating of hair-cell transduction channels. Nat Neurosci 10: 87-92, 2007.
15. Kros CJ, Marcotti W, van Netten SM, Self TJ, Libby RT, Brown SD, Richardson GP, Steel KP. Reduced climbing and increased slipping adaptation in cochlear hair cells of mice with Myo7a mutations. Nat Neurosci 5: 41-47, 2002.
16. Kros CJ, Rüsch A, Richardson GP. Mechano-electrical transducer currents in hair cells of the cultured neonatal mouse cochlea. Proc Biol Sci 249: 185-193, 1992.
17. Martin P, Bozovic D, Choe Y, Hudspeth AJ. Spontaneous oscillation by hair bundles of the bullfrog's sacculus. J Neurosci 23: 4533-4548, 2003.
18. Michalski N, Michel V, Bahloul A, Lefevre G, Barral J, Yagi H, Chardenoux S, Weil D, Martin P, Hardelin JP, Sato M, Petit C. Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning. J Neurosci 27: 6478-6488, 2007.
19. Ricci AJ, Crawford AC, Fettiplace R. Tonotopic variation in the conductance of the hair cell mechanotransducer channel. Neuron 40: 983-990, 2003.
20. Rüsch A, Kros CJ, Richardson GP. Block by amiloride and its derivatives of mechano-electrical transduction in outer hair cells of mouse cochlear cultures. J Physiol 474: 75-86, 1994.
21. Shepherd GM, Corey DP. The extent of adaptation in bullfrog saccular hair cells. J Neurosci 14: 6217-6229, 1994.
22. Stauffer EA, Scarborough JD, Hirono M, Miller ED, Shah K, Mercer JA, Holt JR, Gillespie PG. Fast adaptation in vestibular hair cells requires Myosin-1c activity. Neuron 47: 541-553, 2005.
23. Vollrath MA, Eatock RA. Time course and extent of mechanotransducer adaptation in mouse utricular hair cells: comparison with frog saccular hair cells. J Neurophysiol 90: 2676-2689, 2003.