Epidemiological association between isolated skin marks in newborn infants and single umbilical artery (SUA). Does it have biological plausibility?

American Journal of Medical Genetics, Part A

Volumn 146, Issue 1, 2008, Pages 26-34

  Martínez Frías, María Luisa ^a,b,c   Bermejo, E ^c,d   Mendioroz, J ^c,d   Rodriguez Pinilla E ^c,d   Barcia, J M ^c,d,e   Cozar J A ^c,d,e   Fernandez E ^c,d,e   Gomar, J L ^c,d,e   Lara, A ^c,d,e   Rodriguez A ^c,d,e   Tapia, J M ^c,d,e   Clavo, M J ^c,d,e   Munoz M S ^c,d,e   Olivan Del Cacho M J ^c,d,e   Azua De Brea B ^c,d,e   Martinez M ^c,d,e   Lopez S ^c,d,e   Canduela, V ^c,d,e   Gomez Ullate J ^c,d,e   Felix V ^c,d,e   Garcia A ^c,d,e   Garcia M J ^c,d,e   Huertas, H ^c,d,e   Lopez J M ^c,d,e   Sanchez C ^c,d,e   Vazquez, M S ^c,d,e   Aparicio, P ^c,d,e   Buron E ^c,d,e   Centeno, F ^c,d,e   Mousallem, A G ^c,d,e   Nieto, C ^c,d,e   Barranco, F ^c,d,e   Caubet, I ^c,d,e   Foguet, A ^c,d,e   Garcia M M ^c,d,e   Marti J J ^c,d,e   Marco, J J ^c,d,e   Martinez S ^c,d,e   Puig, I ^c,d,e   Rosal, J ^c,d,e   Vazquez M ^c,d,e   Conde, J F ^c,d,e   Martin F ^c,d,e   Martinez M N ^c,d,e   Robles, P ^c,d,e   Andres M ^c,d,e   Beseler, B ^c,d,e   Climent, S ^c,d,e   Garcia C ^c,d,e   Gonzalez De Dios J ^c,d,e   Jovani, C ^c,d,e   Martinez A ^c,d,e   Sanchis, A ^c,d,e   Arroyo, I ^c,d,e   Galan E ^c,d,e   Contreras, J ^c,d,e   Gomez H ^c,d,e   Rota, L ^c,d,e   Blanco, M ^c,d,e   Martinez M A ^c,d,e   Silveira, M ^c,d,e   Garijo, C ^c,d,e   Egues J ^c,d,e   Lertxundi, M M ^c,d,e   Paisan L ^c,d,e   Perez J L ^c,d,e   Rodriguez M C ^c,d,e   Ramos, A ^c,d,e   Riano, I ^c,d,e   Suarez M E ^c,d,e   Contessotto, C ^c,d,e   Hernandez F ^c,d,e   Lopez J A ^c,d,e   Martin J M ^c,d,e   Penas A ^c,d,e   Rubio, M J ^c,d,e   more..

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

^d ECEMC Working Group

^e NONE

Author keywords

Angiomas; Congenital defects; Frequency; Klippel Trenaunay syndrome; Single umbilical artery; SUA; Vascular malformations

Indexed keywords

ANGIOMA; ANGIOOSTEOHYPERTROPHY SYNDROME; ARTICLE; BIRTH WEIGHT; CASE CONTROL STUDY; CONGENITAL BLOOD VESSEL MALFORMATION; CONGENITAL MALFORMATION; CONTROLLED STUDY; DISEASE ASSOCIATION; GESTATIONAL AGE; HEAD CIRCUMFERENCE; HUMAN; INFANT; MAJOR CLINICAL STUDY; NEVUS; NEWBORN; PLACENTA WEIGHT; PRIORITY JOURNAL; SINGLE UMBILICAL ARTERY; SKIN MANIFESTATION; SPAIN;

EID: 37549024949     PISSN: 15524825     EISSN: 15524833     Source Type: Journal    
DOI: 10.1002/ajmg.a.32050     Document Type: Article

References (22)

1. Antaya RJ. 2001. Infantile hemangioma. In: Ortone JP, Wells MJ, Perry V, Gelfand JM, James WD, editors. eMedicine Dermatology. St. Peterburg: eMedicine Corp, 2001/eMedicine Dermatology (journal serial online) 2002. Available at http://www.emedicine.com/derm/topic201.htm.
2. Barnes CM, Huang S, Kaipainen A, Sanoudou D, Chen EJ, Eichler GS, Guo Y, Yu Y, Ingber DE, Mulliken JB, Beggs AH, Folkman J, Fishman SJ. 2005. Evidence by molecular profiling for a placental origin of infantile hemangioma. Proc Natl Acad Sci USA 102:19097-19102.
3. Burns AJ, Kaplan LC, Mulliken JB. 1991. Is there an association between hemangioma and syndromes with dysmorphic features? Pediatrics 88:1257-1267.
4. Chiller KG, Pasaro D, Frieden IJ. 2002. Hemangiomas of infancy: Clinical characteristics, morphologic subtypes, and their relationship to race ethnicity, and sex. Arch Dermatol 138: 1567-1576.
5. Cohen MM Jr. 2006. Vascular update: Morphogenesis, tumors, malformations, and molecular dimensions. Am J Med Genet Part A 140A:2013-2038.
6. Haggstrom AN, Drolet BA, Baselga E, Chamlin SL, Garzon MC, Horii KA, Lucky AW, Mancini AJ, Metry DW, Newell B, Nopper AJ, Frieden IJ. 2006a. Prospective study of infantile hemangiomas: Clinical characteristics predicting complications and treatment. Pediatrics 118:882-887.
7. Haggstrom AN, Lammer EJ, Schneider RA, Marcucio R, Frieden IJ. 2006b. Patterns of infantile hemangiomas: New clues to hemangioma pathogenesis and embryonic facial development. Pediatrics 117:698-703.
8. Hoeger PH, Martinez A, Maerker J, Harper JI. 2004. Vascular anomalies in Proteus syndrome. Clin Exp Dermatol 29:222-230.
9. Lapunzina P, Camelo JS, Rittler M, Castilla EE. 2002. Risks of congenital anomalies in large for gestational age infants. J Pediatr 140:200-204.
10. Martínez-Frías ML. 2001. Approaches to the analysis of infants with multiple congenital anomalies. Am J Med Genet 101:33-35.
11. Martínez-Frías ML. 2004. Segmentation anomalies of the vertebras and ribs: One expression of the primary developmental field. Am J Med Genet Part A 128A:127-131.
12. Martínez-Frías ML, Bermejo E, Rodríguez-Pinilla E, Frías JL. 1998. Congenital anomalies in the offspring of mothers with a bicornuate uterus. Pediatrics 101: http://www.pediatrics.org/cgi/content/full/ 101/4/e10.
13. Martínez-Frías ML, Bermejo E, Rodríguez-Pinilla E, Prieto D. Grupo de Periférico del ECEMC. 2006. Características de los niños recién nacidos con y sin arteria umbilical única, en dos series consecutivas de nacimientos, una de niños con defectos congénitos y otra sin defectos congénitos. An Pediatr 65:541-550.
14. Martínez-Frías ML, Bermejo E, Rodriguez-Pinilla E, Prieto-Merino D. Does single umbilical artery (SUA) predict for any type of congenital defect? Clinical-epidemiological analysis of a large series of consecutive malformed infants. Am J Med Genet Part A (in press).
15. Mendioroz J, Cuevas L, Bermejo E, Martínez-Frías ML. 2006. Clinical and genetic aspects of the hamartoneoplastic syndromes that can be diagnosed during the first three days of life. Review. Bol ECEMC Rev Dismorfol Epidemiol 5: 2-18. Available at http://bvs.isciii.es/mono/pdf/CIAC_05.pdf (abstracts in English).
16. Metry DW, Haggstrom AN, Drolet BA, Baselga E, Chamlin S, Garzon M, Horii K, Lucky A, Mancini AJ, Newell B, Nopper A, Heyer G, Frieden IJ. 2006. A prospective study of PHACE syndrome in infantile hemangiomas: Demographic features, clinical findings, and complications. Am J Med Genet Part A 140A:975-986.
17. Mulliken JB, Glowacki J. 1982. Hemangiomas and vascular malformations in infants and children: A classification based on endothelial characteristics. Plast Reconstr Surg 69:412-422.
18. North PE, Waner M, James CA, Mizeracki A, Frieden IJ, Mihm MC Jr. 2001. Congenital nonprogressive hemangioma: A distinct clinicopathologic entity unlike infantile hemangioma. Arch Dermatol 137:1607-1620.
19. Peng HH, Wang TH, Chao AS, Chang YL, Shieh SC, Chang SD. 2006. Klippel-Trenaunay-Weber syndrome involving fetal thigh: Prenatal presentations and outcomes. Prenat Diagn 26:825-830.
20. Redondo P. 2004. Classification of vascular anomalies (tumours and malformations). Clinical characteristics and natural history. An Sist Sanit Navar 27:9-25.
21. Romero AM, Echebarría A, Sierrasesúmaga L. 2004. Vascular malformations as syndromic markers. An Sist Sanit Navar 27:45-56.
22. Rothschild BM, Tanke DH, Helbling M II, Martin LD. 2003. Epidemiologic study of tumors in dinosaurs. Naturwissenschaften 90:495-500.