Role of Ca2+-sensitization in attenuated carbachol-induced contraction of the colon in a rat model of colitis

European Journal of Pharmacology

Volumn 579, Issue 1-3, 2008, Pages 365-373

  Al Jarallah, Aishah ^a   Khan, Islam ^a   Oriowo, Mabayoje A ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Ca2+ sensitization; Colitis; Contractility; PKC; RhoA Rho kinase

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CALCIUM ION; CARBACHOL; PROTEIN KINASE C; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; CALCIUM; TRINITROBENZENESULFONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLITIS; COLON; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; INTESTINE CONTRACTION; MALE; MYOFILAMENT; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE; SPRAGUE DAWLEY RAT; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING; ANIMAL; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; GENE EXPRESSION REGULATION; INFLAMMATION; METABOLISM; MUSCLE CONTRACTION; PATHOLOGY; PATHOPHYSIOLOGY;

ANIMALS; BLOTTING, WESTERN; CALCIUM; CARBACHOL; COLITIS; COLON; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INFLAMMATION; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; TRINITROBENZENESULFONIC ACID;

EID: 37549021173     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.10.069     Document Type: Article

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