Early and late effects of cardiac resynchronization therapy on force-frequency relation and contractility regulating gene expression in heart failure patients

Heart Rhythm

Volumn 5, Issue 1, 2008, Pages 52-59

  Mullens, Wilfried ^a   Bartunek, Jozef ^a   Wilson Tang, W H ^b   Delrue, Leen ^a   Herbots, Lieven ^c   Willems, Rik ^c   De Bruyne, Bernard ^a   Goethals, Marc ^a   Verstreken, Sofie ^a   Vanderheyden, Marc ^a  

^a CARDIOVASCULAR CENTER   (Belgium)

^b LERNER RESEARCH INSTITUTE   (United States)

^c UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Cardiac resynchronization; Contractility; Gene expression; Heart failure; Remodeling

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ADENOSINE TRIPHOSPHATASE (CALCIUM) 2ALPHA; APELIN; BETA 1 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LOOP DIURETIC AGENT; MESSENGER RNA; PHOSPHOLAMBAN; PROTEIN DERIVATIVE; SODIUM CALCIUM EXCHANGE PROTEIN; SPIRONOLACTONE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CARDIAC RESYNCHRONIZATION THERAPY; CLINICAL ARTICLE; CONGESTIVE CARDIOMYOPATHY; DIASTOLE; DOWN REGULATION; FEMALE; FORCE; FREQUENCY MODULATION; GENE EXPRESSION REGULATION; HEART FAILURE; HEART LEFT VENTRICLE CONTRACTILITY; HEART LEFT VENTRICLE ENDSYSTOLIC VOLUME; HEART LEFT VENTRICLE PRESSURE; HEART LEFT VENTRICLE VOLUME; HEART PACING; HEART RATE; HUMAN; IDIOPATHIC DISEASE; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARCOLEMMA; SARCOPLASMIC RETICULUM; SYSTOLE; TWO DIMENSIONAL ECHOCARDIOGRAPHY; UPREGULATION;

AGED; CARDIAC PACING, ARTIFICIAL; DIASTOLE; FEMALE; GENE EXPRESSION; HEALTH STATUS INDICATORS; HEART FAILURE; HEART VENTRICLES; HUMANS; MALE; MYOCARDIAL CONTRACTION; PROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STROKE VOLUME; TIME FACTORS;

EID: 37549019687     PISSN: 15475271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hrthm.2007.09.009     Document Type: Article

References (36)

1. Cleland J.G., Daubert J.C., Erdmann E., et al., Cardiac Resynchronization-Heart Failure (CARE-HF) Study Investigators. The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med 352 (2005) 1539-1549
2. Linde C., Leclercq Ch., Rex S., et al. Long-term benefits of biventricular pacing in congestive heart failure: results from the MUltisite STImulation in Cardiomyopathy (MUSTIC) study. J Am Coll Cardiol 40 (2002) 111-118
3. Leclercq C., and Kass D.A. Retiming the failing heart: principles and current clinical status of cardiac resynchronization. J Am Coll Cardiol 39 (2002) 194-201
4. Breithardt O.A., Sinha A.M., Schwammenthal E., et al. Acute effects of cardiac resynchronization therapy on functional mitral regurgitation in advanced systolic heart failure. J Am Coll Cardiol 41 (2003) 765-770
5. Steendijk P., Tulner S.A., Bax J.J., et al. Hemodynamic effects of long-term cardiac resynchronization therapy: analysis by pressure-volume loops. Circulation 113 (2006) 1295-1304
6. Bowditch H.P. Über die Eigenthümlichkeiten der Reizbarkeit, welche Muskelfasern des Herzens zeigen. Ber Sachs Ges Wiss 23 (1871) 652-689
7. Alpert N.R., Leavitt B.J., Ittleman F.P., et al. A mechanistic analysis of the force-frequency relation in non-failing and progressively failing human myocardium. Basic Res Cardiol 93 Suppl 1 (1998) 23-32
8. Mulieri L.A., Hasenfuss G., Leavitt B., et al. Altered myocardial force-frequency relation in human heart failure. Circulation 85 (1992) 1743-1750
9. Vollmann D., Luthje L., Schott P., et al. Biventricular pacing improves the blunted force-frequency relation present during univentricular pacing in patients with heart failure and conduction delay. Circulation 113 (2006) 953-959
10. Bombardini T., Agrusta M., Natsvlishvili N., et al. Noninvasive assessment of left ventricular contractility by pacemaker stress echocardiography. Eur J Heart Fail 7 (2005) 173-181
11. Bombardini T., Correia M.J., Cicerone C., et al. Force-frequency relationship in the echocardiography laboratory: a noninvasive assessment of Bowditch treppe?. J Am Soc Echocardiogr 16 (2003) 646-655
12. Penicka M., Bartunek J., De Bruyne B., et al. Improvement of left ventricular function after cardiac resynchronization therapy is predicted by tissue Doppler imaging echocardiography. Circulation 109 (2004) 978-983
13. Daubert J.C., Ritter P., Le Breton H., et al. Permanent left ventricular pacing with transvenous leads inserted into the coronary veins. Pacing Clin Electrophysiol 21 (1998) 239-245
14. Jansen A.H., Bracke F.A., van Dantzig J.M., et al. Correlation of echo-Doppler optimization of atrioventricular delay in cardiac resynchronization therapy with invasive hemodynamics in patients with heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol 97 (2006) 552-557
15. Vanderheyden M., De Backer T., Rivero-Ayerza M., et al. Tailored echocardiographic interventricular delay programming further optimizes left ventricular performance after cardiac resynchronization therapy. Heart Rhythm 2 (2005) 1066-1072
16. Schiller N.B., Shah P., Crawford M., et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms. J Am Soc Echocardiogr 2 (1989) 358-367
17. Tei C., Ling L.H., Hodge D.O., et al. New index of combined systolic and diastolic myocardial performance: a simple and reproducible measure of cardiac function: a study in normals and dilated cardiomyopathy. J Cardiol 26 (1995) 357-366
18. Thomas J.D. How leaky is that mitral valve?. Simplified Doppler methods to measure regurgitant orifice area. Circulation 95 (1997) 548-550
19. Feldman A.M., Ray P.E., Silan C.M., et al. Selective gene expression in failing human heart. Quantification of steady-state levels of messenger RNA in endomyocardial biopsies using the polymerase chain reaction. Circulation 83 (1991) 1866-1872
20. Hasenfuss G., Reinecke H., Studer R., et al. Relation between myocardial function and expression of sarcoplasmic reticulum Ca2+ ATPase in failing and nonfailing human myocardium. Circ Res 75 (1994) 434-442
21. Pieske B., Kretschmann B., Meyer M., et al. Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human dilated cardiomyopathy. Circulation 92 (1995) 1169-1178
22. Bristow M.R. Why does the myocardium fail?. Insights from basic science. Lancet 352 Suppl 1 (1998) SI8-SI14
23. Hasenfuss G., and Pieske B. Calcium cycling in congestive heart failure. J Mol Cell Cardiol 34 (2002) 951-969
24. Pogwizd S. Increased Na+-Ca2+ exchanger in the failing heart. Circ Res 87 (2000) 641-643
25. Lowes B.D., Gilbert E.M., Abraham W.T., et al. Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents. N Engl J Med 346 (2002) 1357-1365
26. Di Tullio, McCarthy P.M., Smedira N., et al. Reversal of the heart failure phenotype by mechanical unloading (1995), Cleveland Clinic Foundation, Cleveland, Ohio 65 Cleveland Clinic Heart Failure Summit Proceedings
27. Takeishi Y., Jalili T., Hoit B.D., et al. Alterations in Ca2+ cycling proteins and G alpha q signaling after left ventricular assist device support in failing human hearts. Cardiovasc Res 45 (2000) 883-888
28. Dipla K., Mattiello J.A., Jeevanandam V., et al. Myocyte recovery after mechanical circulatory support in humans with end-stage heart failure. Circulation 97 (1998) 2316-2322
29. Szokodi I., Tavi P., Foldes G., et al. Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility. Circ Res 91 (2002) 434-440
30. Chen M.M., Ashley E.A., Deng D.X., et al. Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction. Circulation 108 (2003) 1432-1439
31. Bristow M.R., Ginsburg R., Minobe W., et al. Decreased catecholamine sensitivity and β-adrenergic-receptor density in failing human hearts. N Engl J Med 307 (1982) 205-211
32. Ungerer M., Bohm M., Elce J.S., et al. Altered expression of β-adrenergic receptor kinase and α1-adrenergic receptors in the failing human heart. Circulation 87 (1993) 454-463
33. Najem B., Unger P., Preumont N., et al. Sympathetic control after cardiac resynchronization therapy: responders versus nonresponders. Am J Physiol Heart Circ Physiol 291 (2006) H2647-H2652
34. Slutsky R., Karliner J., Gerber K., et al. Peak systolic blood pressure/end-systolic volume ratio: assessment at rest and during exercise in normal subjects and patients with coronary heart disease. Am J Cardiol 46 (1980) 813-820
35. Kass D.A., Midei M., Graves W., et al. Use of a conductance (volume) catheter and transient inferior vena caval occlusion for rapid determination of pressure-volume relationships in man. Catheteter Cardiovasc Diagn 15 (1988) 192-202
36. Feldman M.D., Alderman J.D., Aroesty J.M., et al. Depression of systolic and diastolic myocardial reserve during atrial pacing tachycardia in patients with dilated cardiomyopathy. J Clin Invest 11 (1988) 1661-1669