메뉴 건너뛰기




Volumn 13, Issue 6, 2007, Pages 504-512

Interferon beta treatment: Bioavailability and antiviral activity in multiple sclerosis patients

Author keywords

HHV 6; Interferon beta; MMP 9; Multiple sclerosis; MxA; TIMP 1

Indexed keywords

GELATINASE B; INTERFERON BETA SERINE; MYXOVIRUS RESISTANCE PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

EID: 37549017273     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.1080/13550280701649670     Document Type: Article
Times cited : (9)

References (37)
  • 1
    • 27144501566 scopus 로고    scopus 로고
    • Differential tropism of human herpesvirus 6 (HHV-6) variants and induction of latency by HHV-6A in oligodendrocytes
    • Ahlqvist, J., Fotheringham, J., Akhyani, N., Yaoo, K., Hahn, A Fogdell and Jacobson (2005) Differential tropism of human herpesvirus 6 (HHV-6) variants and induction of latency by HHV-6A in oligodendrocytes. J NeurVirol, 11, pp. 384-394.
    • (2005) J NeurVirol , vol.11 , pp. 384-394
    • Ahlqvist, J.1    Fotheringham, J.2    Akhyani, N.3    Yaoo, K.4    Fogdell Hahn, A.5    Jacobson6
  • 4
    • 22144466188 scopus 로고    scopus 로고
    • Serum MMP-9/TIMP-1 and MMP-2/TIMP-2 ratios in multiple sclerosis: Relationships with different magnetic resonance imaging measures of disease activity during IFN-beta-1a treatment
    • Avolio, C., Filippi, M., Tortorella, C., Rocca, M. A., Ruggieri, M., Agosta, F., Tomassini, V., Pozzilli, C., Stecchi, S., Giaquinto, P., Livrea, P. and Trojano, M. (2005) Serum MMP-9/TIMP-1 and MMP-2/TIMP-2 ratios in multiple sclerosis: Relationships with different magnetic resonance imaging measures of disease activity during IFN-beta-1a treatment. Mult Scler, 11, pp. 441-446.
    • (2005) Mult Scler , vol.11 , pp. 441-446
    • Avolio, C.1    Filippi, M.2    Tortorella, C.3    Rocca, M.A.4    Ruggieri, M.5    Agosta, F.6    Tomassini, V.7    Pozzilli, C.8    Stecchi, S.9    Giaquinto, P.10    Livrea, P.11    Trojano, M.12
  • 5
    • 0038665165 scopus 로고    scopus 로고
    • High frequency of human herpesvirus 6 DNA in multiple sclerosis plaques isolated by laser microdissection
    • Cermelli, C., Berti, R., Soldan, S. S., Mayne, M., D'ambrosia, J. M., Ludwin, S. K. and Jacobson, S. (2003) High frequency of human herpesvirus 6 DNA in multiple sclerosis plaques isolated by laser microdissection. J Infect Dis, 187, pp. 1377-1387.
    • (2003) J Infect Dis , vol.187 , pp. 1377-1387
    • Cermelli, C.1    Berti, R.2    Soldan, S.S.3    Mayne, M.4    D'ambrosia, J.M.5    Ludwin, S.K.6    Jacobson, S.7
  • 7
    • 0037211715 scopus 로고    scopus 로고
    • Correlation between HHV-6 reactivation and multiple sclerosis disease activity
    • Chapenko, S., Millar, A., Nora, Z., Logina, I., Kukaine, R. and Murovska, M. (2003) Correlation between HHV-6 reactivation and multiple sclerosis disease activity. J Med Virol, 69, pp. 111-117.
    • (2003) J Med Virol , vol.69 , pp. 111-117
    • Chapenko, S.1    Millar, A.2    Nora, Z.3    Logina, I.4    Kukaine, R.5    Murovska, M.6
  • 8
    • 0032893876 scopus 로고    scopus 로고
    • Bioavailability of interferon beta 1b in MS patients with and without neutralizing antibodies
    • Deisenhammer, F., Reindl, M. and Harvey, J. (1999) Bioavailability of interferon beta 1b in MS patients with and without neutralizing antibodies. Neurology, 52, pp. 1239-1243.
    • (1999) Neurology , vol.52 , pp. 1239-1243
    • Deisenhammer, F.1    Reindl, M.2    Harvey, J.3
  • 9
    • 0032494792 scopus 로고    scopus 로고
    • Placebo-controlled multicentre randomised trial of interferon beta-1b in treatment of secondary progressive multiple sclerosis
    • European Study Group on interferon beta-1b in secondary progressive MS
    • European Study Group on interferon beta-1b in secondary progressive MS (1998) Placebo-controlled multicentre randomised trial of interferon beta-1b in treatment of secondary progressive multiple sclerosis. Lancet, 352, pp. 1491-1497.
    • (1998) Lancet , vol.352 , pp. 1491-1497
  • 12
    • 0036828793 scopus 로고    scopus 로고
    • Neutralising antibodies to interferon beta during the treatment of multiple sclerosis
    • Giovannoni, F., Munschauer 3rd, E. and Deisenhammer, F. (2002) Neutralising antibodies to interferon beta during the treatment of multiple sclerosis. J Neurol Neurosurg Psychiatry, 73, pp. 465-469.
    • (2002) J Neurol Neurosurg Psychiatry , vol.73 , pp. 465-469
    • Giovannoni, F.1    Munschauer III, E.2    Deisenhammer, F.3
  • 13
    • 0025981021 scopus 로고
    • T-lymphocyte entry into the central nervous system
    • Hickey, W. F., Hsu, B. L. and Kimura, H. (1991) T-lymphocyte entry into the central nervous system. J Neurosci Res, 28, pp. 254-260.
    • (1991) J Neurosci Res , vol.28 , pp. 254-260
    • Hickey, W.F.1    Hsu, B.L.2    Kimura, H.3
  • 14
    • 8644226947 scopus 로고    scopus 로고
    • Application of real-time RT-PCR to quantifying gene expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human abdominal aortic aneurysm
    • Higashikata, T., Yamagishi, M., Sasaki, H., Minatoya, K., Ogino, H., Ishibashi-Ueda, H., Hao, H., Nagaya, N., Tomoike, H. and Sakamoto, A. (2004) Application of real-time RT-PCR to quantifying gene expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human abdominal aortic aneurysm. Atherosclerosis, 177, pp. 353-360.
    • (2004) Atherosclerosis , vol.177 , pp. 353-360
    • Higashikata, T.1    Yamagishi, M.2    Sasaki, H.3    Minatoya, K.4    Ogino, H.5    Ishibashi-Ueda, H.6    Hao, H.7    Nagaya, N.8    Tomoike, H.9    Sakamoto, A.10
  • 15
    • 0035989161 scopus 로고    scopus 로고
    • Anti-viral properties of interferon beta treatment in patients with multiple sclerosis
    • Hong, J., Tejada-Simón, M. V., Rivera, V. M., Zang, Y CQ and Zhang, J. Z. (2002) Anti-viral properties of interferon beta treatment in patients with multiple sclerosis. Mult scler, 8, pp. 237-242.
    • (2002) Mult Scler , vol.8 , pp. 237-242
    • Hong, J.1    Tejada-Simón, M.V.2    Rivera, V.M.3    Zang, Y.C.Q.4    Zhang, J.Z.5
  • 16
    • 22144443446 scopus 로고    scopus 로고
    • Use of lyophilized standards for the calibration of a newly developed real time PCR assay for human herpes type six (HHV6) variants A and B
    • Hymas, W., Stevenson, J., Taggart, E. W. and Hillyard, D. (2005) Use of lyophilized standards for the calibration of a newly developed real time PCR assay for human herpes type six (HHV6) variants A and B. J Virol Methods, pp. 143-150.
    • (2005) J Virol Methods , pp. 143-150
    • Hymas, W.1    Stevenson, J.2    Taggart, E.W.3    Hillyard, D.4
  • 17
    • 5144235025 scopus 로고    scopus 로고
    • Overexpression of matrix metalloproteinase-1 and -9 mRNA is associated with progression of oral dysplasia to cancer
    • Jordan, R. C., Macabeo-Ong, M., Shiboski, C. H., Dekker, N., Gininger, D. G., Wong, D. T. and Schmidt, B. L. (2004) Overexpression of matrix metalloproteinase-1 and -9 mRNA is associated with progression of oral dysplasia to cancer. Clin Cancer Res, 10, pp. 6460-6465.
    • (2004) Clin Cancer Res , vol.10 , pp. 6460-6465
    • Jordan, R.C.1    Macabeo-Ong, M.2    Shiboski, C.H.3    Dekker, N.4    Gininger, D.G.5    Wong, D.T.6    Schmidt, B.L.7
  • 18
    • 0032948343 scopus 로고    scopus 로고
    • Serum gelatinase B, TIMP-1 and TIMP-2 levels in multiple sclerosis. A longitudinal clinical and MRI study
    • Lee, M. A., Palace, J., Stabler, G., Ford, J., Gearing, A. and Miller, K. (1999) Serum gelatinase B, TIMP-1 and TIMP-2 levels in multiple sclerosis. A longitudinal clinical and MRI study. Brain, 122, pp. 191-197.
    • (1999) Brain , vol.122 , pp. 191-197
    • Lee, M.A.1    Palace, J.2    Stabler, G.3    Ford, J.4    Gearing, A.5    Miller, K.6
  • 19
    • 0034749944 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Multifunctional effectors of inflammation in multiple sclerosis and bacterial meningitis
    • Lepert, D., Lindberg, R. L., Kappos, L. and Leib, S. L. (2001) Matrix metalloproteinases: Multifunctional effectors of inflammation in multiple sclerosis and bacterial meningitis. Brain Res Rev, 36, pp. 249-257.
    • (2001) Brain Res Rev , vol.36 , pp. 249-257
    • Lepert, D.1    Lindberg, R.L.2    Kappos, L.3    Leib, S.L.4
  • 21
    • 0034727595 scopus 로고    scopus 로고
    • Neutralizing antibodies to interferon (IFN) alpha-2a and IFN beta-1a or IFN beta-1b in MS are not cross-reactive
    • Myhr, K. M., Ross, C., Nyland, H. I., Bendtzen, K. and Vedeler, C. A. (2000) Neutralizing antibodies to interferon (IFN) alpha-2a and IFN beta-1a or IFN beta-1b in MS are not cross-reactive. Neurology, 55, pp. 1569-1572.
    • (2000) Neurology , vol.55 , pp. 1569-1572
    • Myhr, K.M.1    Ross, C.2    Nyland, H.I.3    Bendtzen, K.4    Vedeler, C.A.5
  • 23
    • 0242404144 scopus 로고    scopus 로고
    • Measurement of MxA or protein as a biomarker of IFNβ bioactivity
    • Pachner, A. R., Bertolotto, A. and Deisenhammer, F. (2003) Measurement of MxA or protein as a biomarker of IFNβ bioactivity. Neurology, 61, pp. S24-S26.
    • (2003) Neurology , vol.61
    • Pachner, A.R.1    Bertolotto, A.2    Deisenhammer, F.3
  • 24
    • 23144458935 scopus 로고    scopus 로고
    • The importance of measuring IFN-β antibodies bioactivity: Monitoring in MS patients and the effect of anti-IFN-β antibodies
    • Pachner, A. R., Dail, D., Pak, E. and Narayan, K. (2005) The importance of measuring IFN-β antibodies bioactivity: Monitoring in MS patients and the effect of anti-IFN-β antibodies. J Neuroimmunol, 166, pp. 180-188.
    • (2005) J Neuroimmunol , vol.166 , pp. 180-188
    • Pachner, A.R.1    Dail, D.2    Pak, E.3    Narayan, K.4
  • 25
    • 0242333124 scopus 로고    scopus 로고
    • MxA gene expression analysis as an interferon-beta bioactivity measurement in patients with multiple sclerosis and the identification of antibody-mediated decreased bioactivity
    • Pachner, A. R., Narayan, K., Price, N., Hurd, M. and Dail, D. (2003) MxA gene expression analysis as an interferon-beta bioactivity measurement in patients with multiple sclerosis and the identification of antibody-mediated decreased bioactivity. Mol Diagn, 7, pp. 17-25.
    • (2003) Mol Diagn , vol.7 , pp. 17-25
    • Pachner, A.R.1    Narayan, K.2    Price, N.3    Hurd, M.4    Dail, D.5
  • 26
    • 0037180479 scopus 로고    scopus 로고
    • Evidence of Interferon Dose-response: European North American Comparative Efficacy, University of British Columbia MS/MRI Research Group. Randomized, comparative study of interferon beta-1a treatment regimens in MS
    • EVIDENCE Study Group
    • Panitch, H., Goodin, D. S., Francis, G., Chang, P., Coyle, P. K., O'Connor, P., Monaghan, E., Li, D., Weinshenker, B. and EVIDENCE Study Group (2002) Evidence of Interferon Dose-response: European North American Comparative Efficacy, University of British Columbia MS/MRI Research Group. Randomized, comparative study of interferon beta-1a treatment regimens in MS. Neurology, 59, pp. 1496-1506.
    • (2002) Neurology , vol.59 , pp. 1496-1506
    • Panitch, H.1    Goodin, D.S.2    Francis, G.3    Chang, P.4    Coyle, P.K.5    O'Connor, P.6    Monaghan, E.7    Li, D.8    Weinshenker, B.9
  • 27
    • 0025168906 scopus 로고
    • Homing to central nervous system vasculature by antigen-specific lymphocytes.II. Lymphocyte/endothelial cell adhesion during the initial stages of autoimmune demyelination
    • Raine, C. S., Canella, B., Duijvestijn, A. M. and Cross, A. H. (1990) Homing to central nervous system vasculature by antigen-specific lymphocytes.II. Lymphocyte/endothelial cell adhesion during the initial stages of autoimmune demyelination. Lab Invest, 63, pp. 476-489.
    • (1990) Lab Invest , vol.63 , pp. 476-489
    • Raine, C.S.1    Canella, B.2    Duijvestijn, A.M.3    Cross, A.H.4
  • 28
    • 0034881644 scopus 로고    scopus 로고
    • The significance of neutralizing antibodies in patients with multiple sclerosis treated with interferon beta
    • Rice, G. (2001) The significance of neutralizing antibodies in patients with multiple sclerosis treated with interferon beta. Arch Neurol, 58, pp. 1297-1298.
    • (2001) Arch Neurol , vol.58 , pp. 1297-1298
    • Rice, G.1
  • 29
    • 0033763507 scopus 로고    scopus 로고
    • Immunogenicity of interferon-beta in multiple sclerosis patients: Influence of preparation, dosage, dose frequency, and route of administration. Danish Multiple Sclerosis Study Group
    • Ross, C., Clemmesen, K. M. and Svenson, M. (2000) Immunogenicity of interferon-beta in multiple sclerosis patients: Influence of preparation, dosage, dose frequency, and route of administration. Danish Multiple Sclerosis Study Group. Ann Neurol, 48, pp. 706-712.
    • (2000) Ann Neurol , vol.48 , pp. 706-712
    • Ross, C.1    Clemmesen, K.M.2    Svenson, M.3
  • 30
    • 0031841745 scopus 로고    scopus 로고
    • Incidence and significance of neutralizing antibodies to interferon beta-1a in multiple sclerosis. Multiple Sclerosis Collaborative Research Group (MSCRG)
    • Rudick, R. A., Simonian, N. A. and Alam, J. A. (1998) Incidence and significance of neutralizing antibodies to interferon beta-1a in multiple sclerosis. Multiple Sclerosis Collaborative Research Group (MSCRG). Neurology, 50, pp. 1266-1272.
    • (1998) Neurology , vol.50 , pp. 1266-1272
    • Rudick, R.A.1    Simonian, N.A.2    Alam, J.A.3
  • 32
    • 0037161237 scopus 로고    scopus 로고
    • Mechanism of action of interferons and glatiramer acetate in multiple sclerosis
    • Suhayl, D. J. (2002) Mechanism of action of interferons and glatiramer acetate in multiple sclerosis. Neurology, 58, pp. S3-S9.
    • (2002) Neurology , vol.58
    • Suhayl, D.J.1
  • 33
    • 0037309220 scopus 로고    scopus 로고
    • Cross-reactivity with myelin basic protein and human-herpesvirus-6 in multiple sclerosis
    • Tejada-Simon, M. V., Zang, Y CQ, Hong, J., Rivera, V. M. and Zhang, J. Z. (2003) Cross-reactivity with myelin basic protein and human-herpesvirus-6 in multiple sclerosis. Ann Neurol, 53, pp. 189-197.
    • (2003) Ann Neurol , vol.53 , pp. 189-197
    • Tejada-Simon, M.V.1    Zang, Y.C.Q.2    Hong, J.3    Rivera, V.M.4    Zhang, J.Z.5
  • 34
    • 0005489101 scopus 로고    scopus 로고
    • Neutralizing antibodies during treatment of multiple sclerosis with interferon beta-1b: Experience during the first three years
    • The IFNB Multiple Sclerosis Study Group and the University of British Columbia MS/MRI Analysis Group
    • The IFNB Multiple Sclerosis Study Group and the University of British Columbia MS/MRI Analysis Group (1996) Neutralizing antibodies during treatment of multiple sclerosis with interferon beta-1b: Experience during the first three years. Neurology, 47, pp. 889-894.
    • (1996) Neurology , vol.47 , pp. 889-894
  • 35
    • 0029161628 scopus 로고    scopus 로고
    • Interferon beta-1b in the treatment of multiple sclerosis: Final outcome of the randomized controlled trial
    • The IFNB Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group
    • The IFNB Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group (2005) Interferon beta-1b in the treatment of multiple sclerosis: Final outcome of the randomized controlled trial. Neurology, 45, pp. 1277-1285.
    • (2005) Neurology , vol.45 , pp. 1277-1285
  • 36
    • 0037435501 scopus 로고    scopus 로고
    • IFNbeta lowers MMP-9/TIMP-1 ratio, which predicts new enhancing lesions in patients with SPMS
    • Waubant, E., Goodkin, D., Bostrom, A., Bacchetti, P., Hietpas, J., Lindberg, R. and Leppert, D. (2003) IFNbeta lowers MMP-9/TIMP-1 ratio, which predicts new enhancing lesions in patients with SPMS. Neurology, 60, pp. 52-57.
    • (2003) Neurology , vol.60 , pp. 52-57
    • Waubant, E.1    Goodkin, D.2    Bostrom, A.3    Bacchetti, P.4    Hietpas, J.5    Lindberg, R.6    Leppert, D.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.