Substitution of tyrosine 146 in the dI component of proton-translocating transhydrogenase leads to reversible dissociation of the active dimer into inactive monomers

Journal of Biological Chemistry

Volumn 282, Issue 50, 2007, Pages 36434-36443

  Obiozo, U Mirian ^a   Brondijk, T Harma C ^a   White, Andrew J ^a   Van Boxel, Gijs ^a   Dafforn, Tim R ^a   White, Scott A ^a   Jackson, J Baz ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIFFERENTIAL SCANNING CALORIMETRY; DIMERS; ENZYME ACTIVITY; FLUORESCENCE; MONOMERS; PROTEINS;

RHODOSPIRILLUM RUBRUM; TRANSHYDROGENASE; X-RAY STRUCTURES;

AMINO ACIDS;

ALANINE; DIMER; METHYL GROUP; MONOMER; NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) TRANSHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PHENYLALANINE; RECOMBINANT ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; TRYPTOPHAN; TYROSINE;

AMINO ACID SUBSTITUTION; ARTICLE; BETA CHAIN; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISSOCIATION; ENZYME ACTIVITY; ENZYME METABOLISM; ENZYME STRUCTURE; FLUORESCENCE; MOLECULAR INTERACTION; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; RHODOSPIRILLUM RUBRUM; ULTRACENTRIFUGATION;

AMINO ACID SUBSTITUTION; AMINO ACIDS; CALORIMETRY, DIFFERENTIAL SCANNING; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ENZYME ACTIVATION; MUTATION, MISSENSE; NADP TRANSHYDROGENASE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; RHODOSPIRILLUM RUBRUM; STRUCTURE-ACTIVITY RELATIONSHIP; ULTRACENTRIFUGATION;

RHODOSPIRILLUM RUBRUM;

EID: 37549013762     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M705433200     Document Type: Article

References (49)

1. Hanson, R. L., and Rose, C. (1980) J. Bacteriol. 141, 401-404
2. Ambartsoumian, G., Dari, R., Lin, R. T., and Newman, E. B. (1994) Microbiology 140, 1737-1744
3. Oshino, N., and Chance, B. (1977) Biochem. J. 162, 509-525
4. Hickman, J. W., Barber, R. D., Skaar, E. P., and Donohue, T. J. (2002) J. Bacteriol. 184, 400-409
5. Arkblad, E. L., Tuck, S., Pestov, N. B., Dmitriev, R. I., Kostina, M. B., Stenvall, J., Tranberg, M., and Rydstrom, J. (2005) Free Radical Biol. Med. 38, 1518-1525
6. Freeman, H., Shimomura, K., Horner, E., Cox, R. D., and Ashcroft, F. M. (2006) Cell. Metab. 3, 35-45
7. Jackson, J. B. (2003) FEBS Lett. 545, 18-24
8. Jackson, J. B., White, S. A., and Brondijk, T. H. C. (2005) in Biophysical and Structural Aspects of Bioenergetics (Wikstrom, M., ed) pp. 376-393, Royal Society of Chemistry, Cambridge
9. Anderson, W. M., and Fisher, R. R. (1981) Biochim. Biophys. Acta 635, 194-199
10. Wu, L. N. Y., and Fisher, R. R. (1983) J. Biol. Chem. 258, 7847-7851
11. Persson, B., Ahnstrom, G., and Rydstrom, J. (1987) Arch. Biochem. Biophys. 259, 341-349
12. Hou, C., Potier, M., and Bragg, P. D. (1990) Biochim. Biophys. Acta 1018, 61-66
13. Wilson, R., Obiozo, U. M., Quirk, P. G., Besra, G. D., and Jackson, J. B. (2006) Biochim. Biophy. Acta 1537, 215-223
14. Quirk, P. G., Jeeves, M., Cotton, N. P. J., Smith, K. J., and Jackson, J. B. (1999) FEBS Lett. 446, 127-132
15. Venning, J. D., Rodrigues, D. J., Weston, C. J., Cotton, N. P. J., Quirk, P. G., Errington, N., Finet, S., White, S. A., and Jackson, J. B. (2001) J. Biol. Chem. 276, 30678-30685
16. Cotton, N. P. J., White, S. A., Peake, S. J., McSweeney, S., and Jackson, J. B. (2001) Structure 9, 165-176
17. Singh, A., Venning, J. D., Quirk, P., van Boxel, G. I., Rodrigues, D. J., White, S. A., and Jackson, J. B. (2003) J. Biol. Chem. 278, 33208-33216
18. Mather, O. M., van Boxel, G. I., White, S. A., and Jackson, J. B. (2004) Biochemistry 43, 10952-10964
19. Sundaresan, V., Chartron, J., Yamaguchi, M., and Stout, C. D. (2005) J. Mol. Biol. 346, 617-629
20. Bhakta, T., Whitehead, S. J., Snaith, J. S., Dafforn, T. R., Wilkie, J., Rajesh, S., White, S. A., and Jackson, J. B. (2007) Biochemistry 46, 3304-3318
21. Phelps, D. C., and Hatefi, Y. (1985) Biochemistry 24, 3503-3507
22. Phelps, D. C., and Hatefi, Y. (1984) Biochemistry 23, 4475-4480
23. Diggle, C., Hutton, M., Jones, G. R., Thomas, C. M., and Jackson, J. B. (1995) Eur. J. Biochem. 228, 719-726
24. Jeeves, M., Smith, K. J., Quirk, P. G., Cotton, N. P. J., and Jackson, J. B. (1999) J. Biomol. NMR 13, 305-306
25. Bizouarn, T., Grimley, R. L., Diggle, C., Thomas, C. M., and Jackson, J. B. (1997) Biochim. Biophys. Acta 1320, 265-274
26. Diggle, C., Bizouarn, T., Cotton, N. P. J., and Jackson, J. B. (1996) Eur. J. Biochem. 241, 162-170
27. Mejbaum-Katzenellenbogen, S., and Drobryszycka, W. J. (1959) Clin. Chem. Acta 4, 515-522
28. Cunningham, I. J., Williams, R., Palmer, T., Thomas, C. M., and Jackson, J. B. (1992) Biochim. Biophys. Acta 1100, 332-338
29. Brondijk, T. H. C., van Boxel, G. I., Singh, A., Mather, O. M., White, H. A., Quirk, P. G., White, S. A., and Jackson, J. B. (2006) J. Biol. Chem. 281, 13345-13354
30. Clayton, R. K. (1963) Biochim. Biophys. Acta 73, 312-323
31. Schuck, P. (2000) Biophys. J. 78, 1606-1619
32. Schuck, P. (2003) Anal. Biochem. 320, 104-124
33. Fisher, R. R., and Guillory, R. J. (1971) J. Biol. Chem. 246, 4679-4686
34. Buckley, P. A., Jackson, J. B., Schneider, T., White, S. A., Rice, D. W., and Baker, P. J. (2000) Structure 8, 809-815
35. Prasad, G. S., Wahlberg, M., Sridhar, V., Sundaresan, V., Yamaguchi, M., Hatefi, Y., and Stout, C. D. (2002) Biochemistry 41, 12745-12754
36. Johansson, T., Oswald, C., Pedersen, A., Tornroth, S., Okvist, M., Karlsson, B. G., and Rydstrom, J. (2005) J. Mol. Biol. 352, 299-312
37. Balbo, A., and Schuck, P. (2006) Office of Research Services Web Site, dbeps. ors.od.nih.gov/pbr_AUC.htm
38. Broos, J., Gabellieri, E., van Boxel, G. I., Jackson, J. B., and Strambini, G. (2003) J. Biol. Chem. 278, 47578-47584
39. Quirk, P. G., Smith, K. J., Thomas, C. M., and Jackson, J. B. (1999) Biochim. Biophys. Acta 1412, 139-148
40. Grimley, R. L., Quirk, P. G., Bizouarn, T., Thomas, C. M., and Jackson, J. B. (1997) Biochemistry 36, 14762-14770
41. Gupta, S., Quirk, P. G., Venning, J. D., Slade, J., Bizouarn, T., Grimley, R. L., Cotton, N. P. J., and Jackson, J. B. (1998) Biochim. Biophys. Acta 1409, 25-38
42. Diggle, C., Cotton, N. P. J., Grimley, R. L., Quirk, P. G., Thomas, C. M., and Jackson, J. B. (1995) Eur. J. Biochem. 232, 315-326
43. Fersht, A. (1999) Structure and Mechanism in Protein Science, pp. 158-167, W.H. Freeman and Company, New York
44. Chaillan-Huntington, C., Butler, P. J. G., Huntington, J. A., Akin, D., Feldherr, C., and Stewart, M. (2001) J. Mol. Biol. 314, 465-477
45. Bizouarn, T., Diggle, C., and Jackson, J. B. (1996) Eur. J. Biochem. 239, 737-741
46. Jones, S., and Thornton, J. M. (1995) Prog. Biophys. Mol. Biol. 63, 31-65
47. Jackson, J. B., White, S. A., Quirk, P. G., and Venning, J. D. (2002) Biochemistry 41, 4173- 4185
48. van Boxel, G. I., Quirk, P., Cotton, N. J. P., White, S. A., and Jackson, J. B. (2003) Biochemistry 42, 1217-1226
49. Lian, L. U., and Roberts, G. C. K. (1993) in NMR of Macromolecules. A Practical Approach (Roberts, G. C. K., ed) pp. 153-182, IRL Press, Oxford