Severe acute hyperammonemia after brief exposure to valproate

Psychosomatics

Volumn 49, Issue 1, 2008, Pages 82-83

  Eubanks, Aubrey L ^a   Aguirre, Betzabel ^a   Bourgeois, James A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; CARNITINE; CLONAZEPAM; HYDROXYZINE; LACTULOSE; MIRTAZAPINE; VALPROATE SEMISODIUM; VENLAFAXINE;

ACUTE DISEASE; ADULT; ANAMNESIS; ARTICLE; BEDTIME DOSAGE; CASE REPORT; DELIRIUM; DISEASE SEVERITY; FEMALE; HUMAN; HYPERAMMONEMIA; MORNING DOSAGE; TREATMENT OUTCOME;

EID: 37549011032     PISSN: 00333182     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.psy.49.1.82     Document Type: Letter

References (6)

1. Lokrantz C-M, Erikson B, Rosen I, et al: Hyperammonemic encephalopathy induced by a combination of valproate and pivmecillinam. Acta Neurol Scand 2004; 109:297-301
2. Verrotti A, Trotta D, Morgese G, et al: Valproate-induced hyperammonemic encephalopathy. Metab Brain Dis 2002; 17:367-373
3. LoVecchio F, Shriki J, Samaddar R: L-carnitine was safely administered in the setting of valproate toxicity. Am J Emerg Med 2005; 23:321-322
4. Vossler DG, Wilensky AJ, Cawthon DF, et al: Serum and CSF glutamine levels in valproate-related hyperammonemic encephalopathy. Epilepsia 2002; 43:154-159
5. Latour P, Arnaud B, Polard E, et al: Drug-induced encephalopathy in six epileptic patients: topiramate? valproate? or both? Hum Psychopharmacol Clin Exp 2004; 19:193-203
6. Gerstener T, Buesing D, Longin E, et al: Valproic acid-induced encephalopathy: 19 new cases in Germany from 1994 to 2003: a side effect associated with VPA therapy not only in young children. J Seizure 2006; 15:443-448