Brain magnetic resonance imaging white matter lesions are frequent in HTLV-I carriers and do not discriminate from HAM/TSP

AIDS Research and Human Retroviruses

Volumn 23, Issue 12, 2007, Pages 1499-1503

  Morgan, Daniel J ^a   Caskey, Marina F ^a   Abbehusen, Cristiane ^b   Oliveira Filho, Jamary ^c   Araujo, Cesar ^b   Porto, Aurelia F ^c   Santos, Silvane Braga ^c   Orge, Gloria O ^c   Joia, Maria Jose ^c   Muniz, Andre L ^c   Siqueira, Isadora ^c   Glesby, Marshall J ^a   Carvalho, Edgar ^c  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b Image Memorial   (Brazil)

^c FEDERAL UNIVERSITY OF BAHIA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON;

ADULT; ARTICLE; BRAIN DISEASE; BRAZIL; CLINICAL ARTICLE; COGNITION; FEMALE; HUMAN; HUMAN T CELL LEUKEMIA VIRUS 1; HUMAN T CELL LEUKEMIA VIRUS INFECTION; INTERFERON PRODUCTION; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SPASTIC PARAPLEGIA; SPINAL CORD DISEASE; VIRUS CARRIER; VIRUS LOAD; WHITE MATTER;

ADOLESCENT; ADULT; AGED; BRAIN; CARRIER STATE; CROSS-SECTIONAL STUDIES; FEMALE; HTLV-I INFECTIONS; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PARAPARESIS, TROPICAL SPASTIC; PROSPECTIVE STUDIES; VIRAL LOAD;

EID: 37549010756     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.2007.0077     Document Type: Article

References (29)

1. De The G and Bomford R: An HTLV-I vaccine: Why how, for whom? AIDS Res Hum Retroviruses 1993;9:381-386.
2. Orland JR, Engstrom J, Fridey J, et al.: Prevalence and clinical features of HTLV neurologic disease in the HTLV outcomes study. Neurology 2003;61:1588-1594.
3. Hinuma Y, Nagata K, Hanaoka M, et al.: Adult T-cell leukemia: Antigen in an ATL cell line and detection of antibodies to the antigen in human sera. Proc Natl Acad Sci USA 1981;78(10)6476-6480.
4. LaGrenade L, Hanchard B, Fletcher V, Cranston B, and Blattner W: Infective dermatitis of Jamaican children: A marker for HTLV-I infection. Lancet 1990;336(8727):1345-1347.
5. Caskey MF, Morgan DJ, Porto MAF, Giozza SP, Muniz AL, Orge MG, Travassos MJ, Baron Y, Carvalho EM, and Glesby MJ: Clinical manifestations associated with HTLV type I infection: A cross-sectional study. AIDS Res Hum Retroviruses 2007;23(3):365-371.
6. Zunt JR, Alacron JO, Montano S, Longstreth WT Jr, Price R, and Holmes KK: Quantitative assessment of subclinical spasticity in human T-cell lymphotropic virus type I infection. Neurology 1999;53(2):386-390.
7. Castro N, Oliveira P, Junior WR, Muniz A, and Carvalho E: Erectile dysfunction and HTLV-I infection: A silent problem. Int J Impot Res 2005;17:364-369.
8. Nagai M, Usuku K, Matsumoto W, et al.: Analysis of HTLV-I proviral load in 202 HAM/TSP patients and 243 asymptomatic HTLV-I carriers: High proviral load strongly predisposes to HAM/TSP. J Neurovirol 1998;4:586-593.
9. Santos SB, Porto AF, Muniz AL, et al.: Exacerbated inflammatory cellular immune response characteristic of HAM/TSP is observed in a large proportion of HTLV-I asymptomatic carriers. BMC Infect Dis 2004;2:4-7.
10. Bagnato F, Butman JA, Mora CA, et al.: Conventional magnetic resonance imaging features in patients with tropical spastic paraparesis. J Neurovirol 2005;11:525-534.
11. Kira J, Fujihara K, Itoyama Y, et al.: Leukoencephalopathy in HTLV-I associated myelopathy/tropical spastic paraparesis: MRI analysis and a two year follow-up study after corticosteroid therapy. J Neurol Sci 1991;106:41-49.
12. Kuroda Y, Matsui M, Yukitake M, et al.: Assessment of MRI criteria for MS in Japanese MS and HAM/TSP. Neurology 1995;45:30-33.
13. Howard AK, Li DK, and Oger J: MRI contributes to the differentiation between MS and HTLV-I associated myelopathy in British Columbian coastal natives. Can J Neurol Sci 2003;30:41-48.
14. Gessain A and Gout O: Chronic myelopathy associated with human T-lymphotropic virus type I (HTLV-I). Ann Intern Med 1992;117:933-946.
15. Ferraz AC, Gabbai AA, Abdala N, and Nogueira RG: Magnetic resonance in HTLV-1 associated myelopathy [Portuguese]. Arq Neuropsiquiatr 1997;55(4):728-736.
16. Milagres AC, Jorge ML, Marchiori PE, and Segurado AA: Human T cell lymphotropic virus type 1-associated myelopathy in Sao Paulo, Brazil. Epidemiologic and clinical features of a university hospital cohort. Neuroepidemiology 2002;21(3):153-158.
17. Alcindor F, Valderrama R, Canavaggio M, Lee H, et al.: Imaging of human T-lymphotropic virus type I-associated chronic progressive myeloneuropathies. Neuroradiology 1992;35(1):69-74.
18. Melo A, Gomes I, and Mattos K: HTLV-1 associated myelopathies in the city of Salvador, Bahia [Portuguese]. Arq Neuropsiquiatr 1994;52(3):320-325.
19. Rudge P, Ali A, and Cruichshank JK: Multiple sclerosis, tropical spastic paraparesis and HTLV-1 infection in Afro-Caribbean patients in the United Kingdom. J Neurol Neurosurg Psychiatry 1991;54(8):689-694.
20. Godoy AJ, Kira J, Hasou K, and Goto I: Characterization of cerebral white matter lesions of HTLV-I-associated myelopathy/tropical spastic paraparesis in comparison with multiple sclerosis and collagen-vasculitis: A semiquantitative MRI study. J Neurol Sci 1995;133:102-111.
21. Kira J, Minato S, Itoyama Y, Goto I, Kato M, and Hasuo K: Leukoencephalopathy in HTLV-I-associated myelopathy: MRI and EEG data. J Neurol Sci 1988;221-232.
22. Azevedo ES, Fortuna CM, Santos MG, et al.: Spread and diversity of human populations in Bahia, Brazil. Hum Biol 1982;54:329-341.
23. Kurtzke JF: Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology 1983;33:1444-1452.
24. Osame M: Review of WHO Kagoshima meeting and diagnostic guidelines for HAM/TSP. In: Human Retrovirology: HTLV (Blattner W, ed.). Raven Press, New York, 1990, pp. 191-197.
25. Dehee A, Cesaire R, Desire N, et al.: Quantitation of HTLV-I proviral load by a TaqMan real-time PCR assay. J Virol Methods 2002;102:37-51.
26. Victoroff J, Mack WJ, Grafton ST, Schreiber SS, and Chui HC: A method to improve interrater reliability of visual inspection of brain MRI. Neurology 1994;44(12):2267-2276.
27. Fazekas F: Magnetic resonance signal abnormalities in asymptomatic individuals: Their incidence and functional correlates. Eur Neurol 1989;29:164-168.
28. Castro NM, Freitas DM, Junior WR, Muniz A, Oliveira P, and Carvalho E: Urodynamic features of voiding dysfunction in HTLV-I infected individuals. Int Braz J Urol 2007;33(2):238-244; discussion 244-245.
29. Castro-Costa CM, Arȧjo AQC, Barreto MM, et al.: Proposal for diagnostic criteria of tropical spastic paraparesis/HTLV-I- associated myelopathy (TSP/HAM). AIDS Res Hum Retroviruses 2006;22(10):931-935.