Multimodal imaging in neurology: Special focus on MRI applications and MEG

Synthesis Lectures on Biomedical Engineering

Volumn 16, Issue , 2007, Pages 1-79

  Muller, Hans Peter ^a   Kassubeck, Jan ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Diffusion tensor imaging; Functional magnetic resonance imaging; Intermodal multimodality; Intramodal multimodality; Magnetic resonance imaging; Magnetoencephalography; Multimodal imaging

Indexed keywords

BRAIN; IMAGE RESOLUTION; MAGNETIC RESONANCE IMAGING; MAGNETOENCEPHALOGRAPHY;

DIFFUSION TENSOR IMAGING; FUNCTIONAL MAGNETIC RESONANCE IMAGING; INTERMODAL MULTIMODALITY; INTRAMODAL MULTIMODALITY; MULTIMODAL IMAGING;

NEUROLOGY;

EID: 37549008395     PISSN: 19300328     EISSN: 19300336     Source Type: Book Series    
DOI: 10.2200/S00099ED1V01Y200710BME016     Document Type: Article

References (154)

1. J. G. Beaumont, Introduction to Neuropsychology. New York: The Guilford Press; 1983.
2. J. S. George, C. J. Aine, J. C. Mosher, D. M. Schmidt, D. M. Ranken, H. A. Schlitt, C. C. Wood, J. D. Lewine, J. A. Sanders, and J. W. Belliveau, "Mapping function in the human brain with magnetoencephalography, anatomical magnetic resonance imaging, and functional magnetic resonance imaging," Clin. Neurophysiol., vol. 12, no. 5, pp. 406-431, 1995,doi:10.1097/00004691-199509010-00002.
3. C. Stippich, P. Freitag, J. Kassubek, P. Sörös, K. Kamada, H. Kober, K. Schefler, R. Hopfengärtner, D. Bilecen, E. W. Radü, and J. B. Vieth, "Motor, somatosensory and auditory cortex localization by fMRI and MEG," NeuroReport, vol. 9, no. 9, pp. 1953-1957, 1998,doi:10.1097/00001756-199806220-00007.
4. H. Kober, C. Nimsky, M. Moller, P. Hastreiter, R. Fahlbusch, and O. Ganslandt, "Correlation of sensorimotor activation with functional magnetic resonance imaging and magnetoencephalography in presurgical functional imaging: A spatial analysis," NeuroImage, vol. 14, no. 5, pp. 1214-1228, 2001, doi:10.1006/nimg.2001.0909.
5. N. Fujimaki, T. Hayakawa, M. Nielsen, T. R. Knosche, and S. Miyauchi, "An fMRI-constrained MEG source analysis with procedures for dividing and grouping activation," NeuroImage, vol. 17, no. 1, pp. 324-343, 2002, doi:10.1006/nimg.2002.1160.
6. S. Thees, F. Blankenburg, B. Taskin, G. Curio, and A. Villringer, "Dipole source localization and fMRI of simultaneously recorded data applied to somatosensory categorization," NeuroImage, vol. 18, pp. 707-719, 2003, doi:10.1016/S1053-8119(02)00054-X.
7. J. Kassubek, and F. D. Juengling, "Multimodality functional neuroimaging," in Stippich C, Ed. Clinical Functional MRI- Presurgical Functional Neuroimaging. Berlin/Heidelberg/New York: Springer; 2007, pp. 191-210.
8. E. Fukushima and B. W. Roeder, Experimental Pulse NMR- A Nuts and Bolts Approach, 10th ed. Cambridge, MA: Perseus Publishing; 1986.
9. P. T. Callaghan, Principles of Nuclear Magnetic Resonance Microscopy. Oxford: Clarendon Press; 1994.
10. R. Kimmich, NMR Tomography, Diffusometry, Relaxometry. Berlin: Springer; 1997.
11. S. Stapf, and S. Han, NMR Imaging in Chemical Engineering. Weinheim, Germany: Wiley; 2006.
12. F. Bloch, W. W. Hansen, and M. Packard, "The nuclear induction experiment," Phys. Rev., vol. 70, pp. 474-485, 1946, doi:10.1103/PhysRev.70.474.
13. A. Haase, J. Frahm, D. Matthaei, W. Hänicke, and K. D. Merbboldt, "FLASH imaging, rapid NMR imaging using low flip angle pulses," Magn. Reson., vol. 67, pp. 258-266, 1986, doi:10.1016/0022-2364(86)90433- 6.
14. A. Mishra, Y Lu, J. Meng, A. W. Anderson, and Z. Ding Z. "Unified framework for anisotropic, interpolation and smoothing of diffusion tensor images," NeuroImage, vol. 31, no. 4, pp. 1525-1535, 2006, doi:10.1016/j.neuroimage.2006.02.031.
15. R. S. Frackowiak, K.J. Friston, C. D. Frith, R.J. Dolan, and J. C. Mazziotta, Human Brain Function. New York: Academic Press; 1997.
16. A. W. Toga, and J. C. Mazziotta, Brain Mapping - The Methods. San Diego: Academic Press; 1996.
17. D. Le Bihan, Diffusion and Perfusion Magnetic Resonance Imaging -Applications to Functional MRI. New York: Raven Press; 1995.
18. S. Ogawa, T M. Lee, A. R. Kay, and D. W. Tank, "Brain magnetic resonance imaging with contrast dependent on blood oxygenation," Proc. Natl. Acad. Sci. USA, vol. 87, no. 24, pp. 9868-9872, 1990, doi:10.1073/pnas.87.24.9868.
19. S. Ogawa, T. M. Lee, A. S. Nayak, and P. Glynn, "Oxygenation- sensitive contrast in magnetic resonance image of rodent brain at high magnetic fields," Magn. Reson. Med., vol. 14, no. 1, pp. 68-78, 1990, doi:10.1002/mrm.1910140108.
20. P. C. van Zijl, S. M. Eleff, J. A. Ulatowski, J. M. Oja, A. M. Ulug, R. J. Traystman, and R. A. Kauppinen, "Quantitative assessment of blood flow, blood volume and blood oxygenation effects in functional magnetic resonance imaging," Nat Med. vol. 42, no. 2, pp. 159-167, 1998, doi:10.1038/nm0298-159.
21. S. Ogawa, T M. Lee, and B. Barrere, "The sensitivity of magnetic resonance image signals of a rat brain to changes in the cerebral venous blood oxygenation," Magn. Reson. Med., vol. 29, no. 2, pp. 205-210, 1993, doi:10.1002/mrm.1910290208.
22. K. K. Kwong, "Functional MRI with echo planar imaging," Mag. Reson. Quarterly, vol. 11, pp. 1-20, 1995.
23. R. Turner, "Functional mapping of the human brain with MRI," Sem. Neurosci., vol. 7, pp. 179-194, 1995.
24. J. V. Hajnal, R. Myers, A. Oatridge,J. E. Schwieso, I. R. Young, and G. M. Bydder, "Artifacts due to stimulus correlated motion in functional imaging of the brain," Magn. Reson. Med., vol. 31, no. 3, pp. 283-291, 1994, doi:10.1002/mrm.1910310307.
25. R. P. Woods, S. R. Cherry, and J. C. Mazziotta, "Rapid automated algorithm for aligning and reslicing PET images," Comput. Assist. Tomogr. vol. 16, no. 4, pp. 620-633, 1992, doi:10.1097/00004728-199207000- 00024.
26. K. J. Friston, J. Ashburner, C. D. Frith, J. B. Poline, J. D. Heather, and R. S. Frackowiak, "Spatial registration and normalization of images," Hum. Brain Mapp., vol. 3, no. 3, pp. 165-189, 1995, doi:10.1002/hbm.460030303.
27. W. Andrä, H. Nowak, Magnetism in Medicine - A Handbook. Wiley-VCH: Berlin; 1998.
28. P. A. Bandettini, A. Jesmanowicz, E. C. Wong, and J. S. Hyde, "Processing strategies for time-course data sets in functional MRI of the human brain," Magn. Reson. Med., vol. 30, no. 2, pp. 161-173, 1993, doi:10.1002/mrm.1910300204.
29. K. Kuppusamy, W. Lin, and M. Haacke, "Statistical assessment of crosscorrelation and variance methods and the importance of electrocardiogram gating in functional magnetic resonance imaging," Magn. Reson. Imaging, vol. 15, pp. 169-181, 1997, doi:10.1016/S0730-725X(96)00338-4.
30. P. Filzmoser, R. Baumgartner, and E. Moser, "A hierarchical clustering method for analyzing functional MR images," Magn. Res. Imaging, vol. 17, pp. 817-826, 1999, doi:10.1016/S0730-725X(99)00014-4.
31. X. Ding, J. Tkach, P. Ruggieri, and T. Masaryk, "Analysis of time-course functional MRI data with clustering method without use of reference signal," Proc. Int. Soc. Magn. Reson., pp. 630-635, 1994.
32. W. H. Press, S. A. Teukolsky, W. T. Vetterling, and B. P. Flannery, Numerical Recipes in C. New York: Cambridge University Press; 1998.
33. K. J. Friston, C. D. Frith, R. S. Frackowiak and R. Turner, "Characterizing dynamic brain responses with fMRI: A multivariate approach," NeuroImage, vol. 2, no. 2, pp. 166-172, 1995,doi:10.1006/nimg.1995.1019.
34. K. J. Friston, C. D. Frith, R. Turner and R. S. Frackowiak, "Characterizing evoked hemodynamics with Fmri," NeuroImage, vol. 2, no. 2, pp. 157-165, 1995, doi:10.1006/nimg.1995.1018.
35. K. J. Friston, A. P. Holmes, J. B. Poline, P. J. Grasby, S. C. Williams, R. S. Frackowiak, and R. Turner, "Analysis of fMRI time-series revisited," NeuroImage, vol. 2, no. 1, pp. 45-53, 1995,doi:10.1006/nimg.1995.1007.
36. K. J. Friston, A. Holmes, J. B. Poline;, C. J. Price, and C. D. Frith, "Detecting activations in PET and fMRI: Levels of inference and power," NeuroImage, vol. 4, pp. 223-235, 1996, doi:10.1006/nimg. 1996.0074.
37. K.J. Friston, S. Williams, R. Howard, R. S. Frackowiak, and R. Turner, "Movement-related effects in fMRI time-series," Magn. Reson. Med. vol. 35, no. 3, pp. 346-355, 1996.
38. K. J. Friston, C. D. Frith, P. Fletcher, P. F. Liddle, and R. S. Frackowiak "Functional topography: Multidimensional scaling and functional connectivity in the brain," Cereb. Cortex, vol. 6, no. 2, pp. 156-164, 1996, doi:10.1093/cercor/6.2.156.
39. K. J. Friston, O. Josephs, G. Rees and R. Turner, "Nonlinear event-related responses in Fmri," Magn. Reson. Med. vol. 39, no. 1, pp. 41-52, 1998, doi:10.1002/mrm.1910390109.
40. D. Le Bihan, F. Breton, D. Lallemand, M. L. Aubin, J. Vignaud, and M. Laval-Jeantet, "Separation of diffusion and perfusionin intravoxel incoherent motion MR imaging," Radiology, vol. 168, pp. 497-505, 1988.
41. E. R. Melhem, S. Mori, G. Mukundan, M. A. Kraut, M. G. Pomper, and P. C. van Zijl, "Diffusion tensor MR imaging of the brain and white matter tractography," Am. J. Radiol., vol. 178, pp. 3-16, 2002.
42. P. J Basser, J. Mattiello, and D. LeBihan, "Estimation of the effective self-diffusion tensor from the NMR spin echo," Magn. Reson., vol. 103, no. 3, pp. 247-254, 1994, doi:10.1006/jmrb.1994.1037.
43. P.J. Basser, J. Mattiello, and D. LeBihan, "MR diffusion tensor spectroscopy and imaging," Biophysics, vol. 66, no. 1, pp. 259-267, 1994.
44. A. L. Tievsky, T. Ptak, and J. Farkas, "Investigation of apparent diffusion coefficient and diffusion tensor anisotropy in acute and chronic multiple sclerosis lesions," Neuroradiology, vol. 20, pp. 1491-1499, 1999.
45. K. Yamada, O. Kizu, H. Ito, T. Kubota, W. Akada, M. Goto, A. Takada, J. Konishi, H. Sasajima, K. Mineura, S. Mori, and T Nishimura, "Tractography for arteriovenous malformations near the sensorimotor cortices," AJNR Neuroradiol., vol. 26, no. 3, pp. 598-602, 2005.
46. S.-K. Lee, D. I. Kim, J. Kim, D. J. Kim, H. D. Kim, D. S. Kim, and S. Mori, "Diffusiontensor MR imaging and fiber tractography: a new method of describing aberrant fiber connections in developmental CNS anomalies," Radiographics, vol. 25, pp. 53-65, 2005, doi:10.1148/rg.251045085.
47. C. R. Tench, P. S. Morgan, M. Wilson, and L. D. Blumhardt, "White matter mapping using diffusion tensor MRI," Magn. Reson. Med. vol. 47, pp. 967-972, 2002, doi:10.1002/mrm.10144.
48. T. L. Chenevert, J. A. Brunberg, and J. G. Pipe, "Anisotropic diffusion in human white matter: demonstration with MR techniques in vivo," Radiology, vol. 177, no. 2, pp. 401-405, 1990.
49. R. Turner, D. Le Bihan, J. Maier, R. Vavrek, L. K. Hedges, and J. Pekar, "Echo-planar imaging of intravoxel incoherent motion," Radiology, vol. 177, no. 2, pp. 407-414, 1990.
50. E. O. Stejskal, and J. F. Tanner, "Spin diffusion measurements: spin echos in the presence of a time-dependent field gradient," Chem. Phys., vol. 42, pp. 288-292, 1965, doi:10.1063/1.1695690.
51. C. Pierpaoli, P. Jezzard, P. J. Basser, A. Barnett, and G. Di Chiro, "Diffusion tensor MR imaging of the human brain," Radiology, vol. 201, pp. 637-648, 1996.
52. M. Neeman, J. P. Freyer, and L. O. Sillerud, "Pulsed-gradient spin-echo studies in NMR imaging. Effects of the imaging gradients on the determination of diffusion coefficients,"J. Magn. Reson., vol. 90, pp. 303-312, 1990, doi:10.1016/0022-2364(90)90136-W.
53. D. Le Bihan, J.-F. Mangin, C. Poupon, C. A. Clark, S. Pappata, N. Molko, and H. Chabriat, "Diffusion tensor imaging: concepts and applications," Magn. Reson., vol. 13, pp. 534-546, 2001, doi:10.1002/jmri.1076.
54. P. J. Basser, and D. K. Jones, "Diffusion-tensor MRI: theory, experimental design and data analysis - a technical review," NMR Biomed., vol. 15, no. 7-8, pp. 456-467, 2002, doi:10.1002/nbm.783.
55. Y. Shen, D.J. Larkman, S. Counsell, I. M. Pu, D. Edwards, and J. V. Hajnal, "Correction of high-order eddy current induced geometric distortion in diffusion-weighted echo-planar images," Magn. Reson. Med. vol. 52, no. 5, pp. 1184-1189, 2004, doi:10.1002/mrm.20267.
56. B. Herrnberger, "Diffusionstensor-Magnetresonanztomographie," Nervenheilkunde, vol. 23, pp. 50-59, 2004.
57. P.J. Basser, S. Pajevic, C. Pierpaoli,J. Duda, and A. Aldroubi, "In vivo fiber tractography using DT-MRI data," Magn. Reson. Med., vol. 44, no. 4, pp. 625-632, 2000, doi:10.1002/1522-2594(200010)44:4<625::AID- MRM17>3.0.CO;2-O.
58. T. E. Conturo, N. F. Lori, T. S. Cull, E. Akbudak, A. Z. Snyder, J. S. Shimony, R. C. McKinstry, H. Burton, and M. E. Raichle, "Tracking neuronal fiber pathways in the living human brain," Proc. Natl. Acad. Sci. USA, vol. 96, no. 18, pp. 10422-10427, 1999, doi:10.1073/pnas.96.18.10422.
59. S. Mori, B. Cain, V. P. Chacko, and P. C. van Zijl, "Three dimensional tracking of axonal projections in the brain by magnetic resonance imaging," Ann. Neurol., vol. 45, pp. 265-269, 1999, doi:10.1002/1531-8249(199902)45:2<265::AID-ANA21>3.0.CO;2-3.
60. M. Lazar, D. M. Weinstein, J. S. Tsuruda, K. M. Hasan, K. Arfanakis, M. E. Meyerand, B. Badie, H. A. Rowley, V. Haughton, A. Field, and A. L. Alexander, "White matter tractography using diffusion tensor deflection," Hum. Brain Mapp. vol. 18, no. 4, pp. 306-321, 2003, doi:10.1002/hbm. 10102.
61. D. K. Jones, A. Simmons, S. C. R. Williams, and M. A. Horsfield, "Noninvasive assessment of axonal fiber connectivity in the human brain via diffusion tensor MRI," Magn. Reson. Med, vol. 42, pp. 37-41, 1999, doi:10.1002/(SICI)1522-2594(199907)42:1<37::AID-MRM7>3.0.CO;2-O.
62. T. E. Behrens, H. J. Berg, S. Jbabdi, M. F. Rushworth, and M. W. Woolrich, "Probabilistic diffusion tractography with multiple fibre orientations: What can we gain?" NeuroImage, vol. 34, no. 1, pp. 144-155, 2007, doi:10.1016/j.neuroimage.2006.09.018.
63. M. Hämäläinen, R. Hari, R. J. Ilmoniemi, J. Knuutila, and O. V. Lounasmaa, "Magnetoencephalography - theory, instrumentation, and applications to noninvasive studies of the working human brain," Rev. Mod. Phys., vol. 65, pp. 413-497, 1993, doi:10.1103/RevModPhys.65.413.
64. K. J. Friston, K. M. Stephan, J. D. Heather, C. D. Frith, A. A. Ioannides, L. C. Liu, M. D. Rugg, J. Vieth, H. Keber, K. Hunter, and R. S. Frackowiak, "A multivariate analysis of evoked responses in EEG and MEG data," NeuroImage, vol. 3, pp. 167-174, 1996, doi:10.1006/nimg.1996. 0018.
65. O. Ganslandt, R. Fahlbusch, C. Nimsky, H. Kober, M. Moller, R. Steinmeier, J. Romstock, and J. Vieth, "Functional neuronavigation with magnetoencephalography: Outcome in 50 patients with lesions around the motor cortex," Neurosurgery, vol. 91, pp. 73-79,1999.
66. J. Kassubek, C. Stippich, P. Sörös, O. Ganslandt, K. Kamada, R. Hopfengärtner, H. Kober, R. Steinmeierv, and J. Vieth, "A motor field source localization protocol using magnetoencephalography," Biomedizinische Technik., vol. 41, Suppl 1, pp. 334-335, 1996.
67. M. Hämäläinen, and J. Sarvas, "Realistic, conductivity geometry model of the human head for interpretation of neuromagnetic data," IEEE Trans. Biomed. Eng., vol. 36, pp. 165-171, 1989, doi:10.1109/10.16463.
68. D. Geselowitz, "On the magnetic field generated outside an inhomogeneous volume conductor by internal current sources," IEEE Trans. Magn., vol. 6, pp. 346-347, 1970, doi:10.1109/TMAG.1970.1066765.
69. S. Tissari, J. Rahola, "Error analysis of Galerkin method to solve the forward problem in MEG using the boundary element method," Comput Methods Programs Biomed., vol. 72, no. 3, pp. 209-222, 2003, doi:10.1016/S0169-2607(02)00144-X.
70. A. S. Ferguson, X. Zhang and G. Stroink, "A complete linear discretization for calculating the magnetic field using the boundary element method," IEEE Trans. Biomed. Eng., vol. 41, pp. 455-460, 1994, doi:10.1109/10.293220.
71. J. de Munck, "A Linear discretization of the volume conductor boundary integral equation using analytically integrated elements," IEEE Trans. Biomed. Eng., vol. 39, pp. 986-990, 1992, doi:10.1109/10.256433.
72. C. Del Gratta, S. N. Erné, and J. Edrich, "A Linear iterative algorithm for dipole localization," in C. Baumgartner, L. Deecke, G. Stroink, and S. J. Williamson, Eds. Biomagnetism: Fundamental Research and Clinical Applications. Amsterdam: Elsevier Science; 1995, pp. 313-316.
73. Polhemus, 3Spacereg Fasttrak User's Manual. Colchester, Vermont, 1993.
74. H. Lindenthal, H.-P. Müller, A. Pasquarelli, and S. N. Erné, "Versatile optical co-registration system for multimodal marker localization," Biomed. Tech. (Berl), vol. 48, no. 2, pp. 272-274, 2004.
75. J. Talairach, and P. Tournoux, Coplanar Stereotaxic Atlas of the Human Brain. New York: Thieme Medical; 1988.
76. D. L. Collins, P. Neeli, T. M. Peters, and A. C. Evans, "Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space," Comput. Assist. Tomogr., vol. 18, no. 2, pp. 192-205, 1994.
77. M. Brett, I. S. Johnsrude, and A. M. Owen, "The problem of functional localization in the human brain," Nat. Rev. Neurosci., vol. 3, no. 3, pp. 243-249, 2002, doi:10.1038/nm756.
78. J. Ashbumer, and K. J. Friston, "Nonlinear spatial normalization using basis functions," Hum Brain Mapp.,vol. 7, pp. 254-266, 1999, doi:10.1002/(SICI)1097-0193(1999)7:4<254::AIDHBM4>3.0.CO;2-G.
79. A. M. Dale, A. K. Liu, B. R. Fischl, R. L. Buckner, J. W. Belliveau, J. D. Lewine, and E. Halgren, "Dynamic statistical parametric mapping: Combining fMRI and MEG for high-resolution imaging of cortical activity," Neuron, vol. 26, no. 1, pp. 55-67, 2000, doi:10.1016/S0896-6273(00)81138- 1.
80. O. V Lounasmaa, M. Hämäläinen, R. Hari and R. Salmelin, "Information processing in the human brain: magnetoencephalographic approach," Proc. Natl. Acad. Sci. USA, vol. 93, no. 17, pp. 8809-8815,1996, doi:10.1073/pnas.93.17.8809.
81. K. K. Kwong, J. W. Belliveau, D. A. Chesler, I. E. Goldberg, R. M. Weisskoff, B. P. Poncelet, D. N. Kennedy, B. E. Hoppel, M. S. Cohen, R. Turner, et al., "Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation," Proc. Natl. Acad. Sci. USA, 1992, vol. 89, pp. 5675-5679, doi:10.1073/pnas.89.12.5675.
82. A. Riecker, W. Grodd, U. Klose, J. B. Schulz, K. Gröschel, M. Erb, H. Ackermann, and A. Kastrup, "Relation between regional functional MRI activation and vscular reactivity to carbon dioxide during normal aging," Cereb. Blood Flow Metab., vol. 23, no. 5, pp. 565-573, 2003, doi:10.1097/01.WCB.0000056063.25434.04.
83. H-P Müller, I. de Cesaris, M. de Melis, L. Marzetti, A. Pasquarelli S. N. Erné, A. C. Ludolph, and J. Kassubek, "Open magnetic and electric graphic analysis: comprehensive magnetoencephalographic and functional magnetic resonance imaging in one single software environment," IEEE Eng. Med. Biol. Mag., vol. 24, no. 3, pp. 109-116, 2005.
84. S. N. Erné, A. Pasquarelli, H. Kammrath, S. Della Penna, K. Torquati, V. Pizzella, R. Rossi, C. Granata, and M. Russo, "Argos 55-The New MCG System in Ulm," in T Yoshimoto, M. Kotani, S. Kuriki, H. Karibe, N. Nakasato, Eds. Recent Advances in Biomagnetism. BIOMAG'98, pp. 27-30, 1998.
85. A. Pasquarelli, H. Kammrath, U. Tenner, and S. N. Erné, "The New Ulm Magnetically Shielded Room," in T Yoshimoto, M. Kotani, S. Kuriki, H. Karibe, and N. Nakasato, Eds. Recent Advances in Biomagnetism: BIOMAG'98, 1998, pp. 55-58.
86. H. Lindenthal, H.-P. Müller, A. Pasquarelli, and S. N. Erné, "OptiCoS - a new optical co-registration system for multimodal integration," in Proc. NFSI2001, Innsbruck, Austria, 2001, pp. 127-129.
87. H.-P. Müller, E. Kraft, A. C. Ludolph, and S. N. Erné, "New analysis methods in fMRI analysis: hierarchical cluster analysis for improved signal-to-noise ratio compared to standard techniques," IEEE Eng. Med. Biol. Mag., vol. 21, no. 5, pp. 134-142, 2002.
88. J. Kassubek, F. D. Juengling, A. Baumgartner, A. C. Ludolph, and A.-D. Sperfeld, "Different regional brain volume loss in pure and complicated hereditary spastic, paraparesis: a voxelbased morphometry study, Amyotrophic Leteral Sclerosis 2007," in press.
89. S. Dreha-Kulaczewski, P. Dechent, G. Helms, J. Frahm, J. Gärtnerand K. Brockmann, "Cerebral metabolic and structural alterations in hereditary spastic paraplegia with thin corpus callosum assessed by MRS and DTI," Neuroradiology, vol. 48, no. 12, pp. 893-898, 2006, doi:10.1007/s00234- 006-0148-2.
90. H-P Müller, A. Unrath, A. C. Ludolph AC, and J. Kassubek, "Preservation of diffusion tensor properties during spatial normalization by use of tensor imaging and fiber tracking on a normal brain database," Phys. Med. Biol., vol. 52, no. 6, pp. N99-N109, 2007, doi:10.1088/0031-9155/52/6/N01.
91. T E. Behrens, H. Johansen-Berg, M. W. Woolrich, S. M. Smith, C. A. Wheeler-Kingshott, P. A. Boulby, G. J. Barker, E. L. Sillery, K. Sheehan, O. Ciccarelli, A. J. Thompson, J. M. Brady, and P. M. Matthews, "Noninvasive mapping of connections between human thalamus and cortex using diffusion imaging," Nat. Neurosci., vol. 6, no. 7, pp. 750-757, 2003, doi:10.1038/nn1075.
92. R. A. Kanaan, S. S. Shergill, G. J. Barker, M. Catani, V. W. Ng, R. Howard, P. K. McGuire, and D. K. Jones, "Tract-specific anisotropy measurements in diffusion tensor imaging," Psychiatry Res., vol. 146, no. 1, pp. 73-82, 2006, doi:10.1016/j.pscychresns.2005.11.002.
93. D. C. Alexander, C. Pierpaoli, P.J. Basser, and J. C. Gee, "Spatial transformations of diffusion tensor magnetic resonance images," IEEE Trans. Med. Imaging, vol. 20, no. 11, pp. 1131-1139, 2001, doi:10.1109/42.963816.
94. H. J. Park, M. Kubicki, M. E. Shenton, A. Guimond, R. W. McCarley, S. E. Maier, R. Kikinis, F. A. Jolesz, and C. F. Westin CF, "Spatial normalization of diffusion tensor MRI using multiple channels," NeuroImage, vol. 20, no. 4, pp. 1995-2009, 2003, doi:10.1016/j. neuroimage.2003.08.008.
95. H. J. Park, C. F. Westin, M. Kubicki, S. E. Maier, M. Niznikiewicz, A. Baer, M. Frumin, R. Kikinis, F. A. Jolesz, R. W. McCarley, and M. E. Shenton, "White matter hemisphere asymmetries in healthy subjects and in schizophrenia: a diffusion tensor MRI study," NeuroImage, vol. 23, no. 1, pp. 213-223, 2004, doi:10.1016/j.neuroimage.2004.04.036.
96. S. M. Smith, M. Jenkinson, H. Johansen-Berg, D. Rueckert, T. E. Nichols, C. E. Mackay, K. E. Watkins, O. Ciccarelli, M. Z. Cader, P. M. Matthews, and T. E. Behrens, "Tract-based spatial statistics: Voxelwise analysis of multi-subject diffusion data," NeuroImage, vol. 31, no. 4, pp. 1487-505, 2006, doi:10.1016/j.neuroimage.2006.02.024.
97. S. M. Smith, H. Johansen-Berg, M. Jenkinson, D. Rueckert, T. E. Nichols, K. L. Miller, M. D. Robson, D. K. Jones, J. C. Klein, A. J. Bartsch, and T. E. Behrens, "Acquisition and voxelwise analysis of multi-subject diffusion data with tract-based spatial statistics," Nat. Protoc., vol. 2, no. 3, pp. 499-503, 2007, doi:10.1038/nprot.2007.45.
98. A. Mechelli, C. J. Price, K. J. Friston, and J. Ashbumer, "Voxel-based morphometry of the human brain: methods and applications," Curr. Med. Imaging Rev. vol. 1, pp. 105-113, 2005, doi:10.2174/1573405054038726.
99. C. D. Good, J. Ashbumer, and R. S. Frackowiak, "Computational neuroanatomy: New perspectives for neuroradiology," Rev. Neurol., vol. 157, pp. 797-806, 2001.
100. C. D. Good, I. S. Johnsrude, J. Ashbumer, R. N. Henson, K. J. Friston, and R. S. Frackowiak, "A voxel-based morphometric study of ageing in 465 normal adult human brains," NeuroImage, vol. 14, pp. 21-36, 2001, doi:10.1006/nimg.2001.0786.
101. J. Ashbumer, and K. J. Friston, "Voxel-based morphometry - the methods," NeuroImage, vol. 11, pp. 805-821, 2000, doi:10.1006/nimg.2000.0582.
102. J. Ashbumer, and K. Friston, "Multimodal image coregistration and partitioning - a unified framework," NeuroImage, vol. 6, no. 3, pp. 209-217, 1997, doi:10.1006/nimg.1997.0290.
103. J. Ashbumer, and K. J. Friston, "Why voxel-based morphometry should be used?" NeuroImage, vol. 14, no. 6, pp. 1238-1243, Dec. 2001, doi:10.1006/nimg.2001.0961.
104. R. Peyron, M. Frot, F. Schneider, L. Garcia-Larrea, P. Mertens, F. G Barral, M. Sindou, B. Laurent, and F. Mauguiere, "Role of operculoinsular cortices in human pain processing: converging evidence from PET, fMRI, dipole modeling, and intracerebral recordings of evoked potentials," NeuroImage, vol. 17, no. 3, pp. 1336-1346, 2002, doi:10.1006/nimg.2002. 1315.
105. P. A. Valdes-Sosa, R. Kotter, and K.J. Friston, "Introduction: Multimodal neuroimaging of brain connectivity," Philos. Trans. R. Soc. Lond. Biol. Sci., vol. 360, no. 1457, pp. 865-867, 2005, doi:10.1098/rstb.2005.1655.
106. J. Ashbumer, J. G. Csemansky, C. Davatzikos, N. C. Fox, G. B. Frisoni, and P. M. Thompson, "Computer-assisted imaging to assess brain structure in healthy and diseased brains," Lancet Neurol., vol. 2, pp. 79-88,2003, doi:10.1016/S1474-4422(03)00304-1.
107. S. R. Felber "Magnetic resonance in the differential diagnosis of dementia," Neural. Transm., vol. 109, no. 7-8, pp. 1045-1051, 2002, doi:10.1007/s007020200088.
108. W. L. Au J. R. Adams, A. Troiano, and A. J. Stoessl, "Neuroimaging in Parkinson's disease," Neural. Transm. Suppl., vol. 70, pp. 241-248, 2006.
109. S. Kalra, and D. Arnold, "neuroimaging in amyotrophic lateral sclerosis," Amyotroph. Lateral Scler. Motor Neuron. Disord., vol. 4, no. 4, pp. 243-248, 2003, doi:10.1080/14660820310011269.
110. P. Bartenstein, "PET in neuroscience: dopaminergic, GABA/benzodiazepine, and opiate system." Nuklearmedizin, vol. 43, no. 1, pp. 33-42, 2004.
111. M. Filippi and M. A. Rocca, "Conventional MRI in multiple sclerosis," NeuroImaging, vol. 17, Suppl. 1, pp. 3S-9S, 2007.
112. M. Rovaris, and M. Filippi, "Diffusion tensor MRI in multiple sclerosis," NeuroImaging, vol. 17, Suppl 1, pp. 27S-30S, 2007.
113. N. De Stefano, and M. Filippi, "MR spectroscopy in multiple sclerosis," J NeuroImaging, vol. 17, Suppl. 1, pp. 31S-35S, 2007.
114. M. A. Rocca and M. Filippi, "Functional MRI in multiple sclerosis," NeuroImaging, vol. 17, Suppl 1, pp. 36S-41S, 2007.
115. M. Filippi and F. Agosta, "Magnetization transfer MRI in multiple sclerosis," NeuroImaging, vol. 17, Suppl. 1, pp. 22S-26S, 2007.
116. C. Weiller, A. May, M. Sach, C. Buhmann, and M. Rijntjes, "Role of functional imaging in neurological disorders," Magn. Reson. Imaging, vol. 23, no. 6, pp. 840-850, 2006, doi:10.1002/jmri.20591.
117. K. Kamada, M. Moller, M. Saguer, J. Kassubek, M. Kaltenhauser, H. Kober, M. Uberall, H. Lauffer, D. Wenzel, and J. Vieth, "Localization analysis of neuronal activities in benign rolandic epilepsy using magnetoencephalography, " Neurol. Sci., vol. 154, no. 2, pp. 164-172, 1998, doi:10.1016/S0022-510X(97)00226-8.
118. F. Babiloni, D. Mattia, C. Babiloni, L. Astolfi, S. Salinari, A. Basilisco, P. M. Rossini, M. G. Marciani, and F. Cincotti, "Multimodal integration of EEG, MEG, and fMRI data for the solution of the NeuroImage puzzle," Magn. Reson, Imaging, vol. 22, no. 10, pp. 1471-1476, 2004, doi:10.1016/j.mri.2004.10.007.
119. B. D. Gonsalves, I. Kahn, T Curran, K. A. Norman, and A. D. Wagner, "Memory strength and repetition suppression: Multimodal imaging of medial temporal cortical contributions to recognition," Neuron, vol. 47, no. 5, pp. 751-761, 2005, doi:10.1016/j.neuron.2005.07.013.
120. C. H. Im, H. K. Jung, and N. Fujimaki, "fMRI-constrained MEG source imaging and consideration of fMRI invisible sources," Hum. Brain Mapp., vol. 26, no. 2, pp. 110-118, 2005, doi:10.1002/hbm.20143.
121. P. Jannin, O. J. Fleig, E. Seigneuret, C. Grova, X. Morandi, and J. M. Scarabin, "A data fusion environment for multimodal and multi-informational neuronavigation," Comput Aided Surg., vol. 5, no. 1, pp. 1-10, 2000, doi:10.1002/(SICI)1097-0150(2000)5:1<1::AID-IGSl>3.0.CO;2-4.
122. P. Jannin, X. Morandi, O. J. Fleig, E. Le Rumeur, P. Toulouse, B. Gibaud, and J. M. Scarabin, "Integration of sulcal and functional information for multimodal neuronavigation," Neurosurgery, vol. 96, no. 4, pp. 713-723, 2002.
123. O. Ganslandt, R. Fahlbusch, H. Kober, J. Gralla, and C. Nimsky, "Use of magnetoencephalography and functional neuronavigation in planning and surgery of brain tumors," Nervenarzt, vol. 73, pp. 155-161, 2002.
124. H. Hund, A. R. Rezai, E. Kronberg, J. Cappell, M. Zonenshayn, U. Ribary, P. J. Kelly, and R. Llinas, "Magnetoencephalographic mapping: Basic of a new functional risk profile in the selection of patients with cortical brain lesions," Neurosurgery, vol. 40, pp. 936-942, 1997, doi:10.1097/00006123-199705000-00011.
125. O. Ganslandt, R. Steinmeier, H. Kober, J. Vieth, J. Kassubek, J. Romstock, C. Strauss and R. Fahlbusch, "Magnetic source imaging combined with image-guided frameless stereotaxy: A new method in surgery around the motor strip," Neurosurgery, vol. 41, pp. 621-627, 1997, doi:10.1097/00006123-199709000-00023.
126. O. Ganslandt, M. Buchfelder, P. Hastreiter, P. Grummich, R. Fahlbusch, and C. Nimsky, "Magnetic source imaging supports clinical decision making in glioma patients." Clin. Neurol. Neurosurg., vol. 107, pp. 20-26, 2004, doi:10.1016/j.clineuro.2004.02.027.
127. P. Ossenblok, F. S. Leijten FS, J. de Munck, G. J. Huiskamp, F. Barkhof, and P. Boon, "Magnetic source imaging contributes to the presurgical identification of sensorimotor cortex in patients with frontal lobe epilepsy," Clin, Neurophysiol., vol. 114, pp. 221-232, 2003, doi:10.1016/S1388-2457(02)00369-3.
128. J. S. Ebersole, "Magnetoencephalography/magnetic source imaging in the assessment of patients with epilepsy," Epilepsia, vol. 38, Suppl 4, pp. S1-S5, 1997, doi:10.1111/j.15281157.1997.tb04533.x.
129. M.J. Fischer, G. Scheler, and H. Stefan, "Utilization of magnetoencephalography results to obtain favourable outcomes in epilepsy surgery," Brain, vol. 128, pp. 153-157, 2005, doi:10.1093/brain/ awh333.
130. H. Stefan, C. Hummel, G. Scheler, A. Genow, K. Druschky, C. Tilz, M. Kaltenhauser, R. Hopfengartner, M. Buchfelder, and J. Romstock, "Magnetic brain source imaging of focal epileptic activity: a synopsis of 455 cases," Brain, vol. 126, pp. 2396-2405, 2003, doi:10.1093/brain/awg239.
131. W. J. Marks Jr., "Utility of MEG in presurgical localization," Epilepsy Curr., vol. 4, pp. 208-209, 2004, doi:10.1111/j.1535-7597.2004. 04516.x.
132. R. Firsching, I. Bondar, H.J. Heinze, H. Hinrichs, T. Hagner, J. Heinrich, and A. Belau, "Practicability of magnetoencephalography-guided neuronavigation," Neurosurg. Rev., vol. 25, pp. 73-78,2002, doi:10.1007/s101430100161.
133. A. M. Dale, and E. Halgren, "Spatiotemporal mapping of brain activity by integration of multiple imaging modalities," Curr. Opin. Neurobiol., vol. 11, pp. 202-208, 2001, doi:10.1016/S0959-4388(00)00197-5.
134. B. A. Assaf, K. M. Karkar, K. D. Laxer, P. A. Garcia, E. J. Austin, N. M. Barbaro, and M. J. Aminoff, "Magnetoencephalography source localization and surgical outcome in temporal lobe epilepsy," Clin. Neurophysiol., vol. 115, pp. 2066-2076, 2004, doi:10.1016/j.clinph.2004.04. 020.
135. F. Duffner, D. Freudenstein, H. Schiffbauer, H. Preissl, R. Siekmann, N. Birbaumer, and E. H. Grote, "Combining MEG and MRI with neuronavigation for treatment of an epileptiform spike focus in the precentral region: a technical case report," Surg. Neurol., vol. 59, pp. 40-45,2003, doi:10.1016/S0090-3019(02)00972-2.
136. S. Knake, P. E. Grant, S. M. Stufflebeam, L. L. Wald, H. Shiraishi, F. Rosenow, D. L. Schomer, B. Fischl, A. M. Dale, and E. Halgren, "Aids to telemetry in the presurgical evaluation of epilepsy patients: MRI, MEG and other noninvasive imaging techniques," Suppl. Clin. Neurophysiol., vol. 57, pp. 494-502, 2004.
137. K. Kamada, T Todo, Y. Masutani, S. Aoki, K. Ino, A. Morita, and N. Saito, "Visualization of the frontotemporal language fibers by tractography combined with functional magnetic resonance imaging and magnetoencephalography, " Neurosurgery, vol. 106, no. 1, pp. 90-98, 2007.
138. C. Ramon, J. Haueisen, T Richards, and K. Maravilla "Multimodal imaging of somatosensory evoked cortical activity," Neurol. Clin, Neurophysiol., vol. 96, 2004.
139. A. Stadibauer, C. Nimsky, S. Gruber, E. Moser, T Hammen, T Engelhorn, M. Buchfelder, and O. Ganslandt, "Changes in fiber integrity, diffusivity, and metabolism of the pyramidal tract adjacent to gliomas: a quantitative diffusion tensor fiber tracking and MR spectroscopic imaging study," AJNR Am. J. Neuroradiol, vol. 28, no. 3, pp. 462-469, 2007.
140. M. P. Richardson, K. J. Friston, S. M. Sisodiya, M. J. Koepp, JAshbumer, S. L. Free, D. J. Brooks, and J. S. Duncan, "Cortical grey matter and benzodiazepine receptors in malformations of cortical development. A voxel-based comparison of structural and functional imaging data." Brain, vol. 120, pp. 1961-1973, 1997, doi:10.1093/brain/120.11.1961.
141. J. Kassubek, H.J. Huppertz J. Spreer, and A. Schulze-Bonhage, "Detection and localization of focal cortical dysplasia by voxel-based 3-D MRI analysis," Epilepsia, vol. 43, pp. 596-602, 2002, doi:10.1046/j.1528-1157.2002.41401.x.
142. S. B. Antel, A. Bemasconi, N. Bemasconi, D. L. Collins, R. E. Kearney, R. Shinghal, and D. L. Arnold, "Computational models of MRI characteristics of focal cortical dysplasia improve lesion detection," NeuroImage, vol. 17, pp. 1755-1760, 2002, doi:10.1006/nimg.2002.1312.
143. H.J. Huppertz, C. Grimm, S. FauserJ. Kassubek, I. Mader, A. Hochmuth J. Spreer, and A. Schulze-Bonhage, "Enhanced visualization of blurred gray-white matter junctions in focal cortical dysplasia by voxel-based 3D MRI analysis," Epilepsy Res., vol. 67, pp. 35-50, 2005, doi:10.1016/j.eplepsyres.2005.07.009.
144. J. Kassubek, F. D. Juengling, and A. Otte, "Improved interpretation of cerebral PET with respect to structural MRI changes using combined voxel-based statistical mapping," Eur. J. Nucl. Med., vol. 27, pp. 880, 2000.
145. J. H. Cross, "Functional neuroimaging of malformations of cortical development, " Epileptic Disord, vol. 5, Suppl 2, pp. S73-S80, 2003.
146. R. Wiest, J. Kassubek, K. Schindler, T. J. Loher, C. Kiefer, L. Mariani, M. Wissmeyer, G. Schroth, J. Mathis, B. Weder, and F. D. Juengling, "Comparison of voxel-based 3-D MRI analysis and subtraction ictal SPECT coregistered to MRI in focal epilepsy," Epilepsy Res. vol. 65, pp. 125-133, 2005, doi:10.1016/j.eplepsyres.2005.05.002.
147. F. D. Juengling, J. Kassubek, H. J. Huppertz, T Krause, and T. Els, "Separating functional and structural damage in persistent vegetative state
148. J. Daunizeau, C. Grova, G. Marrelec, J. Mattout, S. Jbabdi, M. Pelegrini-Issac, J. M. Lina, and H. Benali, "Symmetrical event-related EEG/fMRI information fusion in a variational Bayesian framework," NeuroImage, vol. 36, no. 1, pp. 69-87, 2007, doi:10.1016/j.neuroimage. 2007.01.044.
149. B. Fabio, B. Claudio, C. Filippo, R. Paolo Maria, B. Alessandra, A. Laura, and C. Febo, "Multimodal integration of EEG and functional magnetic, resonance recordings," in Proc Conf IEEE Eng. Med. Biol. Soc., vol. 7, pp. 5311-5314, 2004, doi:10.1109/IEMBS.2004.1404483.
150. P. Ritter and A. Villringer, "Simultaneous EEG-Fmri," Neurosci. Biobehav. Rev., vol. 30, no. 6, pp. 823-838, 2006, doi:10.1016/j.neubiorev.2006.06.008.
151. F. S. Leijten, G.J. Huiskamp, I. Hilgersom, and A. C. Van Huffelen "High-resolution source imaging in mesiotemporal lobe epilepsy: a comparison between MEG and simultaneous EEG," Clin. Neurophysiol., vol. 20, pp. 227-238, 2003, doi:10.1097/00004691-20030700000001.
152. J. Gotman, E. Kobayashi, A. P. Bagshaw, C. G. Benar, and F. Dubeau, "Combining EEG and fMRI: A multimodal tool for epilepsy research," Magn. Reson. Imaging, vol. 23, no. 6, pp. 906-920, 2006, doi:10.1002/jmri.20577.
153. G. Lantz, L. Spinelli, R. G. Menendez, M. Seeck, and C. M. Michel, "Localization of distributed sources and comparison with functional MRI," Epileptic Disord. (Special Issue), pp. 45-58, 2001.
154. T. Hammen, M. Schwarz, M. Doelken, F. Kerling, T Engelhom, A. Stadibauer, O. Ganslandt, C. Nimsky, A. Doerfler, and H. Stefan, "IH-NMR spectroscopy indicates severity markers in temporal lobe epilepsy: Correlations between metabolic alterations, seizures, and epileptic discharges in EEG," Epilepsia, vol. 48, no. 2, pp. 263-269, 2007, doi:10.1111/j.l528-1167. 2006.00856.x.