Employing dobutamine as a useful agent to reverse the terlipressin-linked impairments in cardiopulmonary hemodynamics and global oxygen transport in healthy and endotoxemic sheep

Shock

Volumn 29, Issue 1, 2008, Pages 71-77

  Bröking, Katrin ^a   Lange, Matthias ^a,b   Morelli, Andrea ^c   Ertmer, Christian ^a   Aken, Hugo Van ^a   Luecke, Martin ^d   Rehberg, Sebastian ^a   Böwering, Norman ^a   Bone, Hans Georg ^a   Traber, Daniel L ^b   Westphal, Martin ^a,d  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Dobutamine; Endotoxemia; Sepsis; Sheep; Terlipressin; V1 receptor agonist; Vasopressin

Indexed keywords

DOBUTAMINE; SALMONELLA ENDOTOXIN; TERLIPRESSIN;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; BOLUS INJECTION; CARDIOPULMONARY HEMODYNAMICS; COMPARATIVE STUDY; CONTINUOUS INFUSION; CONTROLLED STUDY; DOSE RESPONSE; ENDOTOXEMIA; EWE; FEMALE; HEART INDEX; HYPOTENSION; LUNG VASCULAR RESISTANCE; MEAN ARTERIAL PRESSURE; NONHUMAN; OXYGEN SATURATION; OXYGEN TRANSPORT; PROSPECTIVE STUDY; SHEEP; TACHYCARDIA; VENOUS OXYGEN TENSION;

ANIMALS; BLOOD PRESSURE; DOBUTAMINE; ENDOTOXEMIA; FEMALE; HEMODYNAMICS; INFUSIONS, INTRAVENOUS; LYSINE VASOPRESSIN; OXYGEN; SHEEP; VASCULAR RESISTANCE;

EID: 37549007547     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/shk.0b013e318063e63b     Document Type: Article

References (38)

1. Landry DW, Oliver JA: The pathogenesis of vasodilatory shock. N Engl J Med 345:588-595, 2001.
2. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M: Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345:1368-1377, 2001.
3. Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, Cohen J, Gea-Banacloche J, Keh D, Marshall JC, Parker MM, et al.: Surviving Sepsis Campaign Management Guidelines Committee: Surviving Sepsis Campaign guidelines for the management of severe sepsis and septic shock. Crit Care Med 32:858-873, 2004.
4. Takakura K, Taniguchi T, Muramatsu I, Takeuchi K, Fukuda S: Modification of alpha 1-adrenoreceptors by peroxynitrite as a possible mechanism of systemic hypotension in sepsis. Crit Care Med 30:894-899, 2002.
5. Reid IA: Role of vasopressin deficiency in the vasodilation of septic shock. Circulation 95:1108-1110, 1997.
6. Landry DW, Levin HR, Gallant EM, Ashton RC Jr, Seo S, D'Alessandro D, Oz MC, Oliver JA: Vasopressin deficiency contributes to the vasodilation of septic shock. Circulation 95:1122-1125, 1997.
7. Westphal M, Stubbe H, Sielenkamper AW, Ball C, Van Aken H, Borgulya R, Bone HG: Effects of titrated arginine vasopressin on hemodynamic variables and oxygen transport in healthy and endotoxemic sheep. Crit Care Med 31:1502-1508, 2003.
8. Sun Q, Dimopoulos G, Nguyen DN, Tu Z, Nagy N, Hoang AD, Rogiers P, De Backer D, Vincent JL: Low-dose vasopressin in the treatment of septic shock in sheep. Am J Respir Crit Care Med 168:481-486, 2003.
9. Dunser MW, Mayr AJ, Ulmer H, Knotzer H, Sumann G, Pajk W, Friesenecker B, Hasibeder WR: Arginine vasopressin in advanced vasodilatory shock: a prospective, randomized, controlled study. Circulation 107:2313-2319, 2003.
10. Holmes CL, Walley KR, Chittock DR, Lehman T, Russell JA: The effects of vasopressin on hemodynamics and renal function in severe septic shock: a case series. Intensive Care Med 27:1416-1421, 2001.
11. Malay MB, Ashton RC Jr, Landry DW, Townsend RN: Low-dose vasopressin in the treatment of vasodilatory septic shock. J Trauma 47:699-703, 1999.
12. Leone M, Albanese J, Delmas A, Chaabane W, Garnier F, Martin C: Terlipressin in catecholamine-resistant septic shock patients. Shock 22:314-319, 2004.
13. Morelli A, Rocco M, Conti G, Orecchioni A, De Gaetano A, Cortese G, Coluzzi F, Vernaglione E, Pelaia P, Pietropaoli P: Effects of terlipressin on systemic and regional haemodynamics in catecholamine-treated hyperkinetic septic shock. Intensive Care Med 30:597-604, 2004.
14. Albanese J, Leone M, Delmas A, Martin C: Terlipressin or norepinephrine in hyperdynamic septic shock: a prospective, randomized study. Crit Care Med 33:1897-1902, 2005.
15. Westphal M, Stubbe H, Sielenkamper AW, Borgulya R, Van Aken H, Ball C, Bone HG: Terlipressin dose response in healthy and endotoxemic sheep: impact on cardiopulmonary performance and global oxygen transport. Intensive Care Med 29:301-308, 2003.
16. Scharte M, Meyer J, Van Aken H, Bone HG: Hemodynamic effects of terlipressin (a synthetic analog of vasopressin) in healthy and endotoxemic sheep. Crit Care Med 29:1756-1760, 2001.
17. O'Brien A, Clapp L, Singer M: Terlipressin for norepinephrine-resistant septic shock. Lancet 359:1209-1210, 2002.
18. Westphal M, Bone HG, Van Aken H, Sielenkamper AW: Terlipressin for haemodynamic support in septic patients: a double-edged sword? Lancet 360:1250-1251, 2002.
19. Wimmer A, Stanek B, Kubecova L, Vitovec J, Spinar J, Yilmaz N, Kos T, Hartter E, Frey B, Pacher R: Effects of prostaglandin E1, dobutamine and placebo on hemodynamic, renal and neurohumoral variables in patients with advanced heart failure. Jpn Heart J 40:321-323, 1999.
20. Vincent JL, De Backer D: Inotrope/vasopressor support in sepsis-induced organ hypoperfusion. Semin Respir Crit Care Med 22:61-73, 2001.
21. Martikainen TJ, Uusaro A, Tehunen JJ, Ruokonen E: Dobutamine compensates deleterious hemodynamic and metabolic effects of vasopressin in the splanchnic region in endotoxin shock. Acta Anaesthesiol Scand 48:935-943, 2004.
22. Hiltebrand LB, Kerjci V, Sigurdsson GH: Effects of dopamine, dobutamine, and dopexamine on microcirculatory blood flow in the gastrointestinal tract during sepsis and anesthesia. Anesthesiology 100:1188-1197, 2004.
23. Dyson DH, Sinclair MD: Impact of dopamine or dobutamine infusions on cardiovascular variables after rapid blood loss and volume replacement during isoflurane-induced anesthesia in dogs. Am J Vet Res 67:1121-1130, 2006.
24. Traber DL: Animal models: the sheep. Crit Care Med 28:591-592, 2000.
25. Maybauer MO, Maybauer DM, Traber LD, Westphal M, Enkhbaatar P, Morita N, Jodoin JM, Heggers JP, Herndon DN, Traber DL: Gentamicin improves hemodynamics in ovine septic shock after smoke inhalation injury. Shock 24:226-231, 2005.
26. Maybauer DM, Maybauer MO, Traber LD, Westphal M, Nakano YY, Enkhbaatar P, Morita N, Herndon DN, Traber DL: Effects of severe smoke inhalation injury and septic shock on global hemodynamics and microvascular blood flow in sheep. Shock 26:489-495, 2006.
27. Lange M, Szabo C, Van Aken H, Williams W, Traber DL, Daudel F, Broking K, Salzman AL, Bone HG, Westphal M: Short-term effects of glipizide (an adenosine triphosphate-sensitive potassium channel inhibitor) on cardiopulmonary hemodynamics and global oxygen transport in healthy and endotoxemic sheep. Shock 26:516-521, 2006.
28. Ertmer C, Morelli A, Bone HG, Subbe HD, Schepers R, Van Aken H, Lange M, Bröking K, Lücke M, Traber DL, et al.: Dobutamine reverses the vasopressin-associated impairment in cardiac index and systemic oxygen supply in ovine endotoxemia. Crit Care 10(5):R144, 2006.
29. Dewachter P, Jouan-Hureaux V, Lartaud I, Bello G, de Talance N, Longrois D, Mertes PM: Comparison of arginine vasopressin, terlipressin, or epinephrine to correct hypotension in a model of anaphylactic shock in anesthetized brown Norway rats. Anestesiology 104:734-741, 2006.
30. Westphal M, Sielenkamper AW, Van Aken H, Stubbe HD, Daudel F, Schepers R, Schulte S, Bone HG: Dopexamine reverses the vasopressin-associated impairment in tissue oxygen supply but decreases systemic blood pressure in ovine endotoxemia. Anesth Analg 99:878-885, 2004.
31. Westphal M, Stubbe H, Sielenkämper AW, Ball C, Van Aken H, Borgulya R, Bone H-G: Effects of titrated arginine vasopressin on hemodynamic variables and oxygen transport in healthy and endotoxemic sheep. Crit Care Med 31:1502-1508, 2002.
32. Day TA, Randle JC, Renaud LP: Opposing α- and β-adrenergic mechanisms mediate dose-dependent actions of norepinephrine on supraoptic vasopressin neurons in vivo. Brain Res 358:171-179, 1985.
33. Giusti-Paiva A, de Castro M, Antunes-Rodrigues J, Carnio EC: Inducible nitric oxide synthase pathway in the central nervous system and vasopressin release during experimental septic shock. Crit Care Med 30:1306-1310, 2002.
34. Sharshar T, Calier R, Blanchard A, Feydy A, Gray F, Paillard M, Raphael JC, Gajdos P, Annane D: Depletion of neurohypophyseal content of vasopressin in septic shock. Crit Care Med 30:497-500, 2002.
35. Zerbe RL, Henry DP, Robertson GL: Vasopressin response to orthostatic hypotension: etiologic and clinical implications. Am J Med 74:265-271, 1983.
36. Westphal M, Stubbe H, Sielenkämper AW, Borgulya R, Van Aken H, Ball C, Bone H-G: Terlipressin dose response in healthy and endotoxemic sheep: impact on cardiopulmonary performance and global oxygen transport. Intensive Care Med 29:301-308, 2003.
37. Holmes CL, Landry DW, Granton JT: Science review: vasopressin and the cardiovascular system part 2 - clinical physiology. Crit Care 8:15-23, 2004.
38. Warren BL, Eid A, Singer P, Pillay SS, Carl P, Novak I, Chalupa P, Atherstone A, Penzes I, Kubler A, et al.: KyberSept Trial Study Group: caring for the critically ill patient: high-dose antithrombin III on severe sepsis. A randomized controlled trial. JAMA 286:1869-1887, 2001.