-
1
-
-
5344233478
-
Pulmonary arterial hypertension
-
Farber HW, Loscalzo J. Pulmonary arterial hypertension. N Engl J Med 2004; 351:1655-1665
-
(2004)
N Engl J Med
, vol.351
, pp. 1655-1665
-
-
Farber, H.W.1
Loscalzo, J.2
-
2
-
-
0028519806
-
Hypoxia and endothelial-smooth muscle cell interactions in the lung
-
Kourembanas S, Bernfield M. Hypoxia and endothelial-smooth muscle cell interactions in the lung. Am J Respir Cell Mol Biol 1994; 11:373-374
-
(1994)
Am J Respir Cell Mol Biol
, vol.11
, pp. 373-374
-
-
Kourembanas, S.1
Bernfield, M.2
-
3
-
-
0025342724
-
Pulmonary hypertension due to chronic hypoxia
-
Peacock A. Pulmonary hypertension due to chronic hypoxia. BMJ 1990; 300:763
-
(1990)
BMJ
, vol.300
, pp. 763
-
-
Peacock, A.1
-
4
-
-
0024414987
-
Pressure-induced connective tissue synthesis in pulmonary artery segments is dependent on intact endothelium
-
Tozzi CA, Poiani GJ, Harangozo AM, et al. Pressure-induced connective tissue synthesis in pulmonary artery segments is dependent on intact endothelium. J Clin Invest 1989; 84:1005-1012
-
(1989)
J Clin Invest
, vol.84
, pp. 1005-1012
-
-
Tozzi, C.A.1
Poiani, G.J.2
Harangozo, A.M.3
-
5
-
-
0024510073
-
Acute and chronic hypoxic pulmonary hypertension in guinea pigs
-
Thompson BT, Hassoun PM, Kradin RL, et al. Acute and chronic hypoxic pulmonary hypertension in guinea pigs. J Appl Physiol 1989; 66:920-928
-
(1989)
J Appl Physiol
, vol.66
, pp. 920-928
-
-
Thompson, B.T.1
Hassoun, P.M.2
Kradin, R.L.3
-
6
-
-
0030782624
-
Hypoxia-induced pulmonary hypertension in an optimized environment for the guinea pig
-
Bochnowicz S, Osborn RR, Hay DW, et al. Hypoxia-induced pulmonary hypertension in an optimized environment for the guinea pig. Lab Anim 1997; 31:347-356
-
(1997)
Lab Anim
, vol.31
, pp. 347-356
-
-
Bochnowicz, S.1
Osborn, R.R.2
Hay, D.W.3
-
7
-
-
0024537365
-
Effect of heparin and warfarin on chronic hypoxic pulmonary hypertension and vascular remodeling in the guinea pig
-
Hassoun PM, Thompson BT, Steigman D, et al. Effect of heparin and warfarin on chronic hypoxic pulmonary hypertension and vascular remodeling in the guinea pig. Am Rev Respir Dis 1989; 139:763-768
-
(1989)
Am Rev Respir Dis
, vol.139
, pp. 763-768
-
-
Hassoun, P.M.1
Thompson, B.T.2
Steigman, D.3
-
8
-
-
0023002454
-
Glomerular endothelial cells secrete a heparin like inhibitor and a peptide stimulator of mesangial cell proliferation
-
Castellot JJ Jr, Hoover RL, Karnovsky MJ. Glomerular endothelial cells secrete a heparin like inhibitor and a peptide stimulator of mesangial cell proliferation. Am J Pathol 1986; 125:493-500
-
(1986)
Am J Pathol
, vol.125
, pp. 493-500
-
-
Castellot Jr, J.J.1
Hoover, R.L.2
Karnovsky, M.J.3
-
9
-
-
0028200639
-
Inhibition of hypoxic pulmonary hypertension by heparins of differing in vitro antiproliferative potency
-
Thompson BT, Spence CR, Janssens SP, et al. Inhibition of hypoxic pulmonary hypertension by heparins of differing in vitro antiproliferative potency. Am J Respir Crit Care Med 1994; 149:1512-1517
-
(1994)
Am J Respir Crit Care Med
, vol.149
, pp. 1512-1517
-
-
Thompson, B.T.1
Spence, C.R.2
Janssens, S.P.3
-
10
-
-
0037470456
-
Heparin inhibits SMC growth in the presence of human and fetal bovine serum
-
Cindhuchao N, Quinn DA, Garg HG, et al. Heparin inhibits SMC growth in the presence of human and fetal bovine serum. Biochem Biophys Res Commun 2003; 302:84-88
-
(2003)
Biochem Biophys Res Commun
, vol.302
, pp. 84-88
-
-
Cindhuchao, N.1
Quinn, D.A.2
Garg, H.G.3
-
11
-
-
27644564685
-
Cyclin-dependent kinase inhibitor p27Kip1, but not p21WAF1/Cip1, is required for inhibition of hypoxia-induced pulmonary hypertension and remodeling by heparin in mice
-
Yu L, Quinn DA, Garg HG, et al. Cyclin-dependent kinase inhibitor p27Kip1, but not p21WAF1/Cip1, is required for inhibition of hypoxia-induced pulmonary hypertension and remodeling by heparin in mice. Circ Res 2005; 97:937-945
-
(2005)
Circ Res
, vol.97
, pp. 937-945
-
-
Yu, L.1
Quinn, D.A.2
Garg, H.G.3
-
12
-
-
0032745131
-
Production and chemical processing of low molecular weight heparins
-
Linhardt RJ, Gunay NS. Production and chemical processing of low molecular weight heparins. Semin Thromb Haemost 1999; 25(suppl 3):5-16
-
(1999)
Semin Thromb Haemost
, vol.25
, Issue.SUPPL. 3
, pp. 5-16
-
-
Linhardt, R.J.1
Gunay, N.S.2
-
13
-
-
0032042304
-
Low molecular weight heparin prevents the pulmonary hemodynamic and pathomorphologic effects of endotoxin in a porcine acute lung injury model
-
Darien BJ, Fareed J, Centgraf KS, et al. Low molecular weight heparin prevents the pulmonary hemodynamic and pathomorphologic effects of endotoxin in a porcine acute lung injury model. Shock 1998; 9:274-281
-
(1998)
Shock
, vol.9
, pp. 274-281
-
-
Darien, B.J.1
Fareed, J.2
Centgraf, K.S.3
-
14
-
-
0029780448
-
Are the available low-molecular-weight heparin preparations the same?
-
Fareed J, Jeske W, Hoppensteadt D, et al. Are the available low-molecular-weight heparin preparations the same? Semin Thromb Haemost 1996; 22(suppl 1):77-91
-
(1996)
Semin Thromb Haemost
, vol.22
, Issue.SUPPL. 1
, pp. 77-91
-
-
Fareed, J.1
Jeske, W.2
Hoppensteadt, D.3
-
15
-
-
0031051446
-
Production method affects the pharmacokinetic and ex vivo biological properties of low molecular weight heparins
-
Brieger D, Dawes J. Production method affects the pharmacokinetic and ex vivo biological properties of low molecular weight heparins. Thromb Haemost 1997; 77:317-322
-
(1997)
Thromb Haemost
, vol.77
, pp. 317-322
-
-
Brieger, D.1
Dawes, J.2
-
16
-
-
0016045133
-
Growth of the heart and lungs in hypoxic rodents: A model of human hypoxic disease
-
Hunter C, Barer GR, Shaw JW, et al. Growth of the heart and lungs in hypoxic rodents: a model of human hypoxic disease. Clin Sci Mol Med 1974; 46:375-391
-
(1974)
Clin Sci Mol Med
, vol.46
, pp. 375-391
-
-
Hunter, C.1
Barer, G.R.2
Shaw, J.W.3
-
18
-
-
0018340698
-
The pulmonary circulation: Remodeling in growth and disease: the 1978
-
Reid LM. The pulmonary circulation: remodeling in growth and disease: the 1978 J. Burns Amberson lecture. Am Rev Respir Dis 1979; 119:531-546
-
(1979)
J. Burns Amberson lecture. Am Rev Respir Dis
, vol.119
, pp. 531-546
-
-
Reid, L.M.1
-
19
-
-
0017836440
-
The effect of continued hypoxia on rat pulmonary arterial circulation: An ultrastructural study
-
Meyrick B, Reid L. The effect of continued hypoxia on rat pulmonary arterial circulation: an ultrastructural study. Lab Invest 1978; 38:188-200
-
(1978)
Lab Invest
, vol.38
, pp. 188-200
-
-
Meyrick, B.1
Reid, L.2
-
20
-
-
0029865044
-
Differential effect of three commercial heparins on Na+/H+ exchange and growth of PASMC
-
Dahlberg CG, Thompson BT, Joseph PM, et al. Differential effect of three commercial heparins on Na+/H+ exchange and growth of PASMC. Am J Physiol 1996; 270:L260-L265
-
(1996)
Am J Physiol
, vol.270
-
-
Dahlberg, C.G.1
Thompson, B.T.2
Joseph, P.M.3
-
21
-
-
0019829625
-
Cultured endothelial cells produce a heparin-like inhibitor of smooth muscle cell growth
-
Castellot JJ Jr, Addonizio ML, Rosenberg R, et al. Cultured endothelial cells produce a heparin-like inhibitor of smooth muscle cell growth. J Cell Biol 1981; 90:372-379
-
(1981)
J Cell Biol
, vol.90
, pp. 372-379
-
-
Castellot Jr, J.J.1
Addonizio, M.L.2
Rosenberg, R.3
-
22
-
-
0017576983
-
Suppression by heparin of smooth muscle cell proliferation in injured arteries
-
Clowes AW, Karnowsky MJ. Suppression by heparin of smooth muscle cell proliferation in injured arteries. Nature 1977; 265:625-626
-
(1977)
Nature
, vol.265
, pp. 625-626
-
-
Clowes, A.W.1
Karnowsky, M.J.2
-
23
-
-
0018950165
-
Inhibition of rat arterial smooth muscle cell proliferation by heparin: II. In vitro studies
-
Hoover RL, Rosenberg R, Haering W, et al. Inhibition of rat arterial smooth muscle cell proliferation by heparin: II. In vitro studies. Circ Res 1980; 47:578-583
-
(1980)
Circ Res
, vol.47
, pp. 578-583
-
-
Hoover, R.L.1
Rosenberg, R.2
Haering, W.3
-
24
-
-
0025081635
-
Endothelial heparan sulfate proteoglycan: I. Inhibitory effects on smooth muscle cell proliferation
-
Benitz WE, Kelley RT, Anderson CM, et al. Endothelial heparan sulfate proteoglycan: I. Inhibitory effects on smooth muscle cell proliferation. Am J Respir Cell Mol Biol 1990; 2:13-24
-
(1990)
Am J Respir Cell Mol Biol
, vol.2
, pp. 13-24
-
-
Benitz, W.E.1
Kelley, R.T.2
Anderson, C.M.3
-
25
-
-
0021889240
-
Binding and internalization of heparin by vascular smooth muscle cells
-
Castellot JJ Jr, Wong K, Herman B, et al. Binding and internalization of heparin by vascular smooth muscle cells. J Cell Physiol 1985; 124:13-20
-
(1985)
J Cell Physiol
, vol.124
, pp. 13-20
-
-
Castellot Jr, J.J.1
Wong, K.2
Herman, B.3
-
26
-
-
0020404071
-
Inhibition of vascular smooth muscle cell growth by endothelial cell-derived heparin: Possible role of a platelet endoglycosidase
-
Castellot JJ Jr, Favreau LV, Karnovsky MJ, et al. Inhibition of vascular smooth muscle cell growth by endothelial cell-derived heparin: possible role of a platelet endoglycosidase. J Biol Chem 1982; 257:11256-11260
-
(1982)
J Biol Chem
, vol.257
, pp. 11256-11260
-
-
Castellot Jr, J.J.1
Favreau, L.V.2
Karnovsky, M.J.3
-
27
-
-
0020606230
-
Impairment of hypoxic pulmonary artery remodeling by heparin in mice
-
Hales CA, Kradin RL, Brandstetter RD, et al. Impairment of hypoxic pulmonary artery remodeling by heparin in mice. Am Rev Respir Dis 1983; 128:747-751
-
(1983)
Am Rev Respir Dis
, vol.128
, pp. 747-751
-
-
Hales, C.A.1
Kradin, R.L.2
Brandstetter, R.D.3
-
28
-
-
0012700110
-
Proteoglycans in lung disease
-
Garg HG, Hales CA, eds, New York, NY: Marcel Dekker
-
Garg HG, Roughley PJ, Hales CA. Proteoglycans in lung disease. In: Garg HG, Hales CA, eds. Heparin as a potential therapeutic agent to reverse vascular remodeling. New York, NY: Marcel Dekker, 2003; 377-398
-
(2003)
Heparin as a potential therapeutic agent to reverse vascular remodeling
, pp. 377-398
-
-
Garg, H.G.1
Roughley, P.J.2
Hales, C.A.3
-
29
-
-
0037470456
-
Heparin inhibits SMC growth in the presence of human and fetal bovine serum
-
Cindhuchao N, Quinn DA, Garg HG, et al. Heparin inhibits SMC growth in the presence of human and fetal bovine serum. Biochem Biophys Res Commun 2003; 302:84-88
-
(2003)
Biochem Biophys Res Commun
, vol.302
, pp. 84-88
-
-
Cindhuchao, N.1
Quinn, D.A.2
Garg, H.G.3
-
30
-
-
0035912864
-
Guide to anticoagulant therapy: Heparin; a statement for healthcare professionals from the American Heart Association
-
Hirsh J, Anand SS, Halperin JL, et al. Guide to anticoagulant therapy: heparin; a statement for healthcare professionals from the American Heart Association. Circulation 2001; 103:2994-3018
-
(2001)
Circulation
, vol.103
, pp. 2994-3018
-
-
Hirsh, J.1
Anand, S.S.2
Halperin, J.L.3
-
31
-
-
17444415310
-
Safety profile of different low-molecular weight heparins used at therapeutic dose
-
Gouin-Thibanlt I, Pautas E, Siguret V. Safety profile of different low-molecular weight heparins used at therapeutic dose. Drug Saf 2005; 28:333-349
-
(2005)
Drug Saf
, vol.28
, pp. 333-349
-
-
Gouin-Thibanlt, I.1
Pautas, E.2
Siguret, V.3
-
32
-
-
0026593425
-
Low molecular weight heparin
-
Hirsh J, Levine MN. Low molecular weight heparin. Blood 1992; 79:1-17
-
(1992)
Blood
, vol.79
, pp. 1-17
-
-
Hirsh, J.1
Levine, M.N.2
-
33
-
-
0030858230
-
Low-molecular-weight heparins
-
Weitz JI. Low-molecular-weight heparins. N Engl J Med 1997; 337:688-698
-
(1997)
N Engl J Med
, vol.337
, pp. 688-698
-
-
Weitz, J.I.1
-
34
-
-
0026316713
-
Polycythemia and vascular remodeling in chronic hypoxic pulmonary hypertension in guinea pigs
-
Janssens SP, Thompson BT, Spence CR, et al. Polycythemia and vascular remodeling in chronic hypoxic pulmonary hypertension in guinea pigs. J Appl Physiol 1991; 71:2218-2223
-
(1991)
J Appl Physiol
, vol.71
, pp. 2218-2223
-
-
Janssens, S.P.1
Thompson, B.T.2
Spence, C.R.3
-
35
-
-
0242469234
-
Heparin inhibition of endothelial cell proliferation and organization is dependent on molecular weight
-
Khorana AA, Sahni A, Altland OD, et al. Heparin inhibition of endothelial cell proliferation and organization is dependent on molecular weight. Arterioscler Thromb Vasc Biol 2003; 23:2110-2115
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 2110-2115
-
-
Khorana, A.A.1
Sahni, A.2
Altland, O.D.3
-
36
-
-
0028217757
-
Modulation of human fibroblast activity by selected angiogenesis inhibitors
-
Wong J, Wang N, Miller JW, et al. Modulation of human fibroblast activity by selected angiogenesis inhibitors. Exp Eye Res 1994; 58:439-451
-
(1994)
Exp Eye Res
, vol.58
, pp. 439-451
-
-
Wong, J.1
Wang, N.2
Miller, J.W.3
-
37
-
-
0031560415
-
Influence of molecular weight, protein core and charge of native heparin fractions on pulmonary artery smooth muscle cell proliferation
-
Joseph PA, Garg HG, Thompson BT, et al. Influence of molecular weight, protein core and charge of native heparin fractions on pulmonary artery smooth muscle cell proliferation. Biochem Biophys Res Commun 1997; 241:18-23
-
(1997)
Biochem Biophys Res Commun
, vol.241
, pp. 18-23
-
-
Joseph, P.A.1
Garg, H.G.2
Thompson, B.T.3
-
38
-
-
0024581580
-
Structural determinants of heparin's growth inhibitory activity: Interdependence of oligosaccharide size and charge
-
Wright TC Jr, Castellot JJ Jr, Petitou M, et al. Structural determinants of heparin's growth inhibitory activity: interdependence of oligosaccharide size and charge. J Biol Chem 1989; 264:1534-1542
-
(1989)
J Biol Chem
, vol.264
, pp. 1534-1542
-
-
Wright Jr, T.C.1
Castellot Jr, J.J.2
Petitou, M.3
-
39
-
-
0032702533
-
Structural features and bleeding activity of commercial low molecular weight heparins: Neutralization by ATP and protamine
-
Dietrich CP, Shinjo SK, Moraes FA, et al. Structural features and bleeding activity of commercial low molecular weight heparins: neutralization by ATP and protamine. Semin Thromb Haemost 1999; 25(suppl 3):43-50
-
(1999)
Semin Thromb Haemost
, vol.25
, Issue.SUPPL. 3
, pp. 43-50
-
-
Dietrich, C.P.1
Shinjo, S.K.2
Moraes, F.A.3
-
40
-
-
0025428735
-
Endothelial cell proteoglycans: Possible mediators of vascular responses to injury
-
Benitz WE, Bernfield M. Endothelial cell proteoglycans: possible mediators of vascular responses to injury. Am J Respir Cell Mol Biol 1990; 2:407-408
-
(1990)
Am J Respir Cell Mol Biol
, vol.2
, pp. 407-408
-
-
Benitz, W.E.1
Bernfield, M.2
-
41
-
-
0027223173
-
Effect of the desulfation of heparin on its anticoagulant and anti-proliferative activity
-
Tiozzo R, Cingi MR, Reggiani D, et al. Effect of the desulfation of heparin on its anticoagulant and anti-proliferative activity. Thromb Res 1993; 70:99-106
-
(1993)
Thromb Res
, vol.70
, pp. 99-106
-
-
Tiozzo, R.1
Cingi, M.R.2
Reggiani, D.3
-
42
-
-
4844226355
-
Antiproliferative effects of low molecular weight heparin
-
Fletcher JP, Ao PY, Hawthorne WJ. Antiproliferative effects of low molecular weight heparin. ANZ J Surg 2004; 74:793-796
-
(2004)
ANZ J Surg
, vol.74
, pp. 793-796
-
-
Fletcher, J.P.1
Ao, P.Y.2
Hawthorne, W.J.3
-
43
-
-
0031758671
-
Heparin and low-molecular-weight heparin: Mechanisms of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety
-
Hirsh J, Warkentin TE, Raschke R, et al. Heparin and low-molecular-weight heparin: mechanisms of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety. Chest 1998; 114:489S-510S
-
(1998)
Chest
, vol.114
-
-
Hirsh, J.1
Warkentin, T.E.2
Raschke, R.3
-
44
-
-
24044515025
-
Low molecular weight heparins: Are they different?
-
Fareed J, Hoppensteadt D, Jeske W, et al. Low molecular weight heparins: are they different? Can J Cardiol 1998; 14(suppl E):28E-34E
-
(1998)
Can J Cardiol
, vol.14
, Issue.SUPPL. E
-
-
Fareed, J.1
Hoppensteadt, D.2
Jeske, W.3
|