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Volumn 36, Issue 1, 2008, Pages 24-35
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Disposition and metabolism of [14C]brasofensine in rats, monkeys, and humans
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Author keywords
[No Author keywords available]
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Indexed keywords
5 FLUORO 3 [3 [4 (5 METHOXY 4 PYRIMIDINYL) 1 PIPERAZINYL]PROPYL] 1H INDOLE;
BMS 205912;
BRASOFENSINE;
CARBON 14;
DRUG METABOLITE;
GLUCURONIDE;
N (4 CHLOROPHENYL) N' CYANO N'' (6 CYANO 3,4 DIHYDRO 3 HYDROXY 2,2 DIMETHYL 2H 1 BENZOPYRAN 4 YL)GUANIDINE;
N NORBRASOFENSINE;
O NORBRASOFENSINE;
TESMILIFENE;
UNCLASSIFIED DRUG;
CARBON;
DOPAMINE UPTAKE INHIBITOR;
FUSED HETEROCYCLIC RINGS;
OXIME;
ANIMAL EXPERIMENT;
ARTICLE;
CONTROLLED STUDY;
DEMETHYLATION;
DRUG BIOAVAILABILITY;
DRUG DISPOSITION;
DRUG DISTRIBUTION;
DRUG ELIMINATION;
DRUG FECES LEVEL;
DRUG METABOLISM;
FIRST PASS EFFECT;
HUMAN;
HUMAN TISSUE;
ISOMERIZATION;
MAXIMUM PLASMA CONCENTRATION;
MONKEY;
NONHUMAN;
PLASMA HALF LIFE;
PRIORITY JOURNAL;
RADIOACTIVITY;
RAT;
SINGLE DRUG DOSE;
STEADY STATE;
URINARY EXCRETION;
ANIMAL;
BLOOD;
COMPARATIVE STUDY;
INTRAVENOUS DRUG ADMINISTRATION;
LONG EVANS RAT;
MACACA;
MALE;
METABOLIC CLEARANCE RATE;
METABOLISM;
ORAL DRUG ADMINISTRATION;
SPECIES DIFFERENCE;
TISSUE DISTRIBUTION;
URINE;
RATTUS;
ADMINISTRATION, ORAL;
ANIMALS;
CARBON RADIOISOTOPES;
DOPAMINE UPTAKE INHIBITORS;
HETEROCYCLIC COMPOUNDS, 2-RING;
HUMANS;
INJECTIONS, INTRAVENOUS;
MACACA FASCICULARIS;
MALE;
METABOLIC CLEARANCE RATE;
OXIMES;
RATS;
RATS, LONG-EVANS;
SPECIES SPECIFICITY;
TISSUE DISTRIBUTION;
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EID: 37549004700
PISSN: 00909556
EISSN: 1521009X
Source Type: Journal
DOI: 10.1124/dmd.107.016139 Document Type: Article |
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Times cited : (5)
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References (9)
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