메뉴 건너뛰기




Volumn 108, Issue 1, 2008, Pages 47-52

Gemcitabine and pegylated liposomal doxorubicin alternating with cisplatin plus cyclophosphamide in platinum refractory/resistant, paclitaxel-pretreated, ovarian carcinoma

Author keywords

Chemotherapy; Cisplatin; Cyclophosphamide; Gemcitabine; Liposomal doxorubicin; Ovarian cancer; Refractory; Resistant

Indexed keywords

ANTIBIOTIC AGENT; ANTIEMETIC AGENT; ANTIHISTAMINIC AGENT; CA 125 ANTIGEN; CARBOPLATIN; CISPLATIN; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIRUBICIN; FUROSEMIDE; GEMCITABINE; GRANULOCYTE COLONY STIMULATING FACTOR; IFOSFAMIDE; PACLITAXEL;

EID: 37449029285     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2007.08.061     Document Type: Article
Times cited : (9)

References (36)
  • 2
    • 0041329867 scopus 로고    scopus 로고
    • Arbeitsgemeinschaft Gynakologische Onkologie Ovarian Cancer Study Group. A randomized clinical trial of cisplatin/paclitaxel versus carboplatin/paclitaxel as first-line treatment of ovarian cancer
    • du Bois A., Luck H.J., Meier W., Adams H.P., Mobus V., Costa S., et al. Arbeitsgemeinschaft Gynakologische Onkologie Ovarian Cancer Study Group. A randomized clinical trial of cisplatin/paclitaxel versus carboplatin/paclitaxel as first-line treatment of ovarian cancer. J Natl Cancer Inst 95 17 (2003) 1320-1329
    • (2003) J Natl Cancer Inst , vol.95 , Issue.17 , pp. 1320-1329
    • du Bois, A.1    Luck, H.J.2    Meier, W.3    Adams, H.P.4    Mobus, V.5    Costa, S.6
  • 3
    • 0141688377 scopus 로고    scopus 로고
    • Gynecologic Oncology Group. Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a Gynecologic Oncology Group study
    • Ozols R.F., Bundy B.N., Greer B.E., Fowler J.M., Clarke-Pearson D., Burger R.A., et al. Gynecologic Oncology Group. Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a Gynecologic Oncology Group study. J Clin Oncol 21 17 (Sep 2003) 3194-3200
    • (2003) J Clin Oncol , vol.21 , Issue.17 , pp. 3194-3200
    • Ozols, R.F.1    Bundy, B.N.2    Greer, B.E.3    Fowler, J.M.4    Clarke-Pearson, D.5    Burger, R.A.6
  • 4
    • 0034049605 scopus 로고    scopus 로고
    • Second-line treatment of ovarian cancer
    • Markman M., and Bookman M.A. Second-line treatment of ovarian cancer. Oncologist 5 1 (2000) 26-35
    • (2000) Oncologist , vol.5 , Issue.1 , pp. 26-35
    • Markman, M.1    Bookman, M.A.2
  • 5
    • 0742289996 scopus 로고    scopus 로고
    • Hellenic Cooperative Oncology Group study. Second-line chemotherapy with gemcitabine and carboplatin in paclitaxel-pretreated, platinum-sensitive ovarian cancer patients. A Hellenic Cooperative Oncology Group study
    • Papadimitriou C.A., Fountzilas G., Aravantinos G., Kalofonos C., Moulopoulos L.A., Briassoulis E., et al. Hellenic Cooperative Oncology Group study. Second-line chemotherapy with gemcitabine and carboplatin in paclitaxel-pretreated, platinum-sensitive ovarian cancer patients. A Hellenic Cooperative Oncology Group study. Gynecol Oncol 92 1 (Jan 2004) 152-159
    • (2004) Gynecol Oncol , vol.92 , Issue.1 , pp. 152-159
    • Papadimitriou, C.A.1    Fountzilas, G.2    Aravantinos, G.3    Kalofonos, C.4    Moulopoulos, L.A.5    Briassoulis, E.6
  • 6
    • 33750588670 scopus 로고    scopus 로고
    • AGO-OVAR; NCIC CTG; EORTC GCG. Gemcitabine plus carboplatin compared with carboplatin in patients with platinum-sensitive recurrent ovarian cancer: an intergroup trial of the AGO-OVAR, the NCIC CTG, and the EORTC GCG
    • Pfisterer J., Plante M., Vergote I., du Bois A., Hirte H., Lacave A.J., et al. AGO-OVAR; NCIC CTG; EORTC GCG. Gemcitabine plus carboplatin compared with carboplatin in patients with platinum-sensitive recurrent ovarian cancer: an intergroup trial of the AGO-OVAR, the NCIC CTG, and the EORTC GCG. J Clin Oncol 24 29 (2006) 4699-4707
    • (2006) J Clin Oncol , vol.24 , Issue.29 , pp. 4699-4707
    • Pfisterer, J.1    Plante, M.2    Vergote, I.3    du Bois, A.4    Hirte, H.5    Lacave, A.J.6
  • 7
    • 33646726747 scopus 로고    scopus 로고
    • Management of platinum-sensitive recurrent ovarian cancer
    • Pfisterer J., and Ledermann J.A. Management of platinum-sensitive recurrent ovarian cancer. Semin Oncol 33 2 Suppl 6 (2006) S12-S16
    • (2006) Semin Oncol , vol.33 , Issue.2 SUPPL. 6
    • Pfisterer, J.1    Ledermann, J.A.2
  • 8
    • 0035056187 scopus 로고    scopus 로고
    • Second-line therapy for potentially platinum-sensitive recurrent ovarian cancer: what is optimal treatment?
    • Markman M. Second-line therapy for potentially platinum-sensitive recurrent ovarian cancer: what is optimal treatment?. Gynecol Oncol 81 1 (2001) 1-2
    • (2001) Gynecol Oncol , vol.81 , Issue.1 , pp. 1-2
    • Markman, M.1
  • 9
    • 0037862963 scopus 로고    scopus 로고
    • ICON and AGO Collaborators. Paclitaxel plus platinum-based chemotherapy versus conventional platinum-based chemotherapy in women with relapsed ovarian cancer: the ICON4/AGO-OVAR-2.2 trial
    • Parmar M.K., Ledermann J.A., Colombo N., du Bois A., Delaloye J.F., Kristensen G.B., et al. ICON and AGO Collaborators. Paclitaxel plus platinum-based chemotherapy versus conventional platinum-based chemotherapy in women with relapsed ovarian cancer: the ICON4/AGO-OVAR-2.2 trial. Lancet 361 9375 (2003) 2099-2106
    • (2003) Lancet , vol.361 , Issue.9375 , pp. 2099-2106
    • Parmar, M.K.1    Ledermann, J.A.2    Colombo, N.3    du Bois, A.4    Delaloye, J.F.5    Kristensen, G.B.6
  • 10
    • 0030272511 scopus 로고    scopus 로고
    • Activity of gemcitabine in patients with advanced ovarian cancer: responses seen following platinum and paclitaxel
    • Shapiro J.D., Millward M.J., Rischin D., Michael M., Walcher V., Francis P.A., et al. Activity of gemcitabine in patients with advanced ovarian cancer: responses seen following platinum and paclitaxel. Gynecol Oncol 63 1 (1996) 89-93
    • (1996) Gynecol Oncol , vol.63 , Issue.1 , pp. 89-93
    • Shapiro, J.D.1    Millward, M.J.2    Rischin, D.3    Michael, M.4    Walcher, V.5    Francis, P.A.6
  • 11
    • 18844438857 scopus 로고    scopus 로고
    • Gemcitabine monotherapy in recurrent ovarian cancer: from the bench to the clinic
    • Bookman M.A. Gemcitabine monotherapy in recurrent ovarian cancer: from the bench to the clinic. Int J Gynecol Cancer 15 Suppl 1 (2005) 12-17
    • (2005) Int J Gynecol Cancer , vol.15 , Issue.SUPPL. 1 , pp. 12-17
    • Bookman, M.A.1
  • 12
    • 0031055830 scopus 로고    scopus 로고
    • Phase II study of liposomal doxorubicin in refractory ovarian cancer: antitumor activity and toxicity modification by liposomal encapsulation
    • Muggia F.M., Hainsworth J.D., Jeffers S., Miller P., Groshen S., Tan M., et al. Phase II study of liposomal doxorubicin in refractory ovarian cancer: antitumor activity and toxicity modification by liposomal encapsulation. J Clin Oncol 15 3 (1997) 987-993
    • (1997) J Clin Oncol , vol.15 , Issue.3 , pp. 987-993
    • Muggia, F.M.1    Hainsworth, J.D.2    Jeffers, S.3    Miller, P.4    Groshen, S.5    Tan, M.6
  • 13
    • 0033850066 scopus 로고    scopus 로고
    • Phase II study of liposomal doxorubicin in platinum- and paclitaxel-refractory epithelial ovarian cancer
    • Gordon A.N., Granai C.O., Rose P.G., Hainsworth J., Lopez A., Weissman C., et al. Phase II study of liposomal doxorubicin in platinum- and paclitaxel-refractory epithelial ovarian cancer. J Clin Oncol 18 17 (2000) 3093-3100
    • (2000) J Clin Oncol , vol.18 , Issue.17 , pp. 3093-3100
    • Gordon, A.N.1    Granai, C.O.2    Rose, P.G.3    Hainsworth, J.4    Lopez, A.5    Weissman, C.6
  • 14
    • 0035879099 scopus 로고    scopus 로고
    • Recurrent epithelial ovarian carcinoma: a randomized phase III study of pegylated liposomal doxorubicin versus topotecan
    • Gordon A.N., Fleagle J.T., Guthrie D., Parkin D.E., Gore M.E., and Lacave A.J. Recurrent epithelial ovarian carcinoma: a randomized phase III study of pegylated liposomal doxorubicin versus topotecan. J Clin Oncol 19 14 (2001) 3312-3322
    • (2001) J Clin Oncol , vol.19 , Issue.14 , pp. 3312-3322
    • Gordon, A.N.1    Fleagle, J.T.2    Guthrie, D.3    Parkin, D.E.4    Gore, M.E.5    Lacave, A.J.6
  • 15
    • 33846989436 scopus 로고    scopus 로고
    • Randomized phase III trial of gemcitabine (GEM) versus pegylated liposomal doxorubicin (PLDOX) for patients (pts) with platinum-resistant (pt-r) ovarian cancer (oc) undergoing second or third-line chemotherapy (ct)
    • Mutch D., Orlando M., Teneriello T., Gordon A., McMeekin S., Goss T., et al. Randomized phase III trial of gemcitabine (GEM) versus pegylated liposomal doxorubicin (PLDOX) for patients (pts) with platinum-resistant (pt-r) ovarian cancer (oc) undergoing second or third-line chemotherapy (ct). Eur J Cancer Suppl 3 (2005) 262
    • (2005) Eur J Cancer Suppl , vol.3 , pp. 262
    • Mutch, D.1    Orlando, M.2    Teneriello, T.3    Gordon, A.4    McMeekin, S.5    Goss, T.6
  • 16
    • 37449010072 scopus 로고    scopus 로고
    • The Multicentre Italian Trials in Ovarian Cancer (MITO) Group. A randomized phase III study of gemcitabine (GEM) versus pegylated liposomal doxorubicin (PLD) in progressive/recurrent ovarian cancer (OC)
    • [abstr 5506]
    • Ferrandina G., Lorusso D., Pignata S., Breda E., Savarese A., Nardi M., et al. The Multicentre Italian Trials in Ovarian Cancer (MITO) Group. A randomized phase III study of gemcitabine (GEM) versus pegylated liposomal doxorubicin (PLD) in progressive/recurrent ovarian cancer (OC). Proc Am Soc Clin Oncol 25 (2007) 18S [abstr 5506]
    • (2007) Proc Am Soc Clin Oncol , vol.25
    • Ferrandina, G.1    Lorusso, D.2    Pignata, S.3    Breda, E.4    Savarese, A.5    Nardi, M.6
  • 17
    • 0042232332 scopus 로고    scopus 로고
    • Workshop: options for therapy in ovarian cancer
    • Herzog T.J., Holloway R.W., and Stuart G.C. Workshop: options for therapy in ovarian cancer. Gynecol Oncol 90 3 Pt 2 (2003) S45-S50
    • (2003) Gynecol Oncol , vol.90 , Issue.3 PART 2
    • Herzog, T.J.1    Holloway, R.W.2    Stuart, G.C.3
  • 18
    • 0242266498 scopus 로고    scopus 로고
    • Phase II study of liposomal doxorubicin and gemcitabine in the salvage treatment of ovarian cancer
    • D'Agostino G., Ferrandina G., Ludovisi M., Testa A., Lorusso D., Gbaguidi N., et al. Phase II study of liposomal doxorubicin and gemcitabine in the salvage treatment of ovarian cancer. Br J Cancer 89 7 (2003) 1180-1184
    • (2003) Br J Cancer , vol.89 , Issue.7 , pp. 1180-1184
    • D'Agostino, G.1    Ferrandina, G.2    Ludovisi, M.3    Testa, A.4    Lorusso, D.5    Gbaguidi, N.6
  • 19
    • 22944470084 scopus 로고    scopus 로고
    • Gemcitabine plus pegylated liposomal doxorubicin in patients with advanced epithelial ovarian cancer resistant/refractory to platinum and/or taxanes. A HeCOG phase II study
    • Skarlos D.V., Kalofonos H.P., Fountzilas G., Dimopoulos M.A., Pavlidis N., Razis E., et al. Gemcitabine plus pegylated liposomal doxorubicin in patients with advanced epithelial ovarian cancer resistant/refractory to platinum and/or taxanes. A HeCOG phase II study. Anticancer Res 25 4 (2005) 3103-3108
    • (2005) Anticancer Res , vol.25 , Issue.4 , pp. 3103-3108
    • Skarlos, D.V.1    Kalofonos, H.P.2    Fountzilas, G.3    Dimopoulos, M.A.4    Pavlidis, N.5    Razis, E.6
  • 20
    • 0029067168 scopus 로고
    • Carboplatin reinduction after taxane in patients with platinum-refractory epithelial ovarian cancer
    • Kavanagh J., Tresukosol D., Edwards C., Freedman R., Gonzalez de Leon C., Fishman A., et al. Carboplatin reinduction after taxane in patients with platinum-refractory epithelial ovarian cancer. J Clin Oncol 13 7 (1995) 1584-1588
    • (1995) J Clin Oncol , vol.13 , Issue.7 , pp. 1584-1588
    • Kavanagh, J.1    Tresukosol, D.2    Edwards, C.3    Freedman, R.4    Gonzalez de Leon, C.5    Fishman, A.6
  • 21
    • 33846990923 scopus 로고    scopus 로고
    • Biweekly gemcitabine and cisplatin in platinum-resistant/refractory, paclitaxel-pretreated, ovarian and peritoneal carcinoma
    • Bozas G., Bamias A., Koutsoukou V., Efstathiou E., Gika D., Papadimitriou C.A., et al. Biweekly gemcitabine and cisplatin in platinum-resistant/refractory, paclitaxel-pretreated, ovarian and peritoneal carcinoma. Gynecol Oncol 104 3 (2007) 580-585
    • (2007) Gynecol Oncol , vol.104 , Issue.3 , pp. 580-585
    • Bozas, G.1    Bamias, A.2    Koutsoukou, V.3    Efstathiou, E.4    Gika, D.5    Papadimitriou, C.A.6
  • 22
    • 0025139309 scopus 로고
    • A five-drug alternating chemotherapy regimen for patients with advanced epithelial ovarian cancer
    • Lawton F., Meanwell C., Mould J., and Blackledge G. A five-drug alternating chemotherapy regimen for patients with advanced epithelial ovarian cancer. Gynecol Oncol 36 1 (1990) 19-22
    • (1990) Gynecol Oncol , vol.36 , Issue.1 , pp. 19-22
    • Lawton, F.1    Meanwell, C.2    Mould, J.3    Blackledge, G.4
  • 23
    • 0032940255 scopus 로고    scopus 로고
    • Schedule-dependent interaction of doxorubicin, paclitaxel and gemcitabine in human breast cancer cell lines
    • Zoli W., Ricotti L., Barzanti F., Dal Susino M., Frassineti G.L., Milandri C., et al. Schedule-dependent interaction of doxorubicin, paclitaxel and gemcitabine in human breast cancer cell lines. Int J Cancer 80 3 (1999) 413-416
    • (1999) Int J Cancer , vol.80 , Issue.3 , pp. 413-416
    • Zoli, W.1    Ricotti, L.2    Barzanti, F.3    Dal Susino, M.4    Frassineti, G.L.5    Milandri, C.6
  • 24
    • 0036409129 scopus 로고    scopus 로고
    • CA125 response: can it replace the traditional response criteria in ovarian cancer?
    • Guppy A.E., and Rustin G.J. CA125 response: can it replace the traditional response criteria in ovarian cancer?. Oncologist 7 5 (2002) 437-443
    • (2002) Oncologist , vol.7 , Issue.5 , pp. 437-443
    • Guppy, A.E.1    Rustin, G.J.2
  • 26
    • 84908844821 scopus 로고
    • World Health Organization: WHO Handbook for Reporting Results of Cancer Treatment
    • Switzerland: World Health Organization, Geneva
    • World Health Organization: WHO Handbook for Reporting Results of Cancer Treatment. WHO Offset Publication vol. 48 (1979), Switzerland: World Health Organization, Geneva
    • (1979) WHO Offset Publication , vol.48
  • 27
  • 28
    • 0036388148 scopus 로고    scopus 로고
    • Relapsed ovarian cancer: challenges and management strategies for a chronic disease
    • Armstrong D.K. Relapsed ovarian cancer: challenges and management strategies for a chronic disease. Oncologist 7 Suppl 5 (2002) 20-28
    • (2002) Oncologist , vol.7 , Issue.SUPPL. 5 , pp. 20-28
    • Armstrong, D.K.1
  • 29
    • 0024364233 scopus 로고
    • Carboplatin in refractory epithelial ovarian cancer
    • Kavanagh J.J., and Nicaise C. Carboplatin in refractory epithelial ovarian cancer. Semin Oncol 16 2 Suppl 5 (1989) 45-48
    • (1989) Semin Oncol , vol.16 , Issue.2 SUPPL. 5 , pp. 45-48
    • Kavanagh, J.J.1    Nicaise, C.2
  • 32
    • 33645406772 scopus 로고    scopus 로고
    • A phase II study of pegylated liposomal doxorubicin oxaliplatin and cyclophosphamide as second-line treatment in relapsed ovarian carcinoma
    • Valerio M.R., Tagliaferri P., Raspagliesi F., Fulfaro F., Badalamenti G., Arcara C., et al. A phase II study of pegylated liposomal doxorubicin oxaliplatin and cyclophosphamide as second-line treatment in relapsed ovarian carcinoma. Int J Gynecol Cancer 16 Suppl 1 (2006) 79-85
    • (2006) Int J Gynecol Cancer , vol.16 , Issue.SUPPL. 1 , pp. 79-85
    • Valerio, M.R.1    Tagliaferri, P.2    Raspagliesi, F.3    Fulfaro, F.4    Badalamenti, G.5    Arcara, C.6
  • 33
    • 33745994656 scopus 로고    scopus 로고
    • Combined PEG liposomal doxorubicin and gemcitabine are active and have acceptable toxicity in patients with platinum-refractory and -resistant ovarian cancer after previous platinum-taxane therapy: a phase II Austrian AGO study
    • Petru E., Angleitner-Boubenizek L., Reinthaller A., Deibl M., Zeimet A.G., Volgger B., et al. Combined PEG liposomal doxorubicin and gemcitabine are active and have acceptable toxicity in patients with platinum-refractory and -resistant ovarian cancer after previous platinum-taxane therapy: a phase II Austrian AGO study. Gynecol Oncol 102 2 (2006) 226-229
    • (2006) Gynecol Oncol , vol.102 , Issue.2 , pp. 226-229
    • Petru, E.1    Angleitner-Boubenizek, L.2    Reinthaller, A.3    Deibl, M.4    Zeimet, A.G.5    Volgger, B.6
  • 34
    • 22644432004 scopus 로고    scopus 로고
    • Gemcitabine and liposomal doxorubicin in the salvage treatment of ovarian cancer: updated results and long-term survival
    • Ferrandina G., Paris I., Ludovisi M., D'Agostino G., Testa A., Lorusso D., et al. Gemcitabine and liposomal doxorubicin in the salvage treatment of ovarian cancer: updated results and long-term survival. Gynecol Oncol 98 2 (2005) 267-273
    • (2005) Gynecol Oncol , vol.98 , Issue.2 , pp. 267-273
    • Ferrandina, G.1    Paris, I.2    Ludovisi, M.3    D'Agostino, G.4    Testa, A.5    Lorusso, D.6
  • 35
    • 0037224987 scopus 로고    scopus 로고
    • Gemcitabine reverses cisplatin resistance: demonstration of activity in platinum- and multidrug-resistant ovarian and peritoneal carcinoma
    • Rose P.G., Mossbruger K., Fusco N., Smrekar M., Eaton S., and Rodriguez M. Gemcitabine reverses cisplatin resistance: demonstration of activity in platinum- and multidrug-resistant ovarian and peritoneal carcinoma. Gynecol Oncol 88 1 (2003) 17-21
    • (2003) Gynecol Oncol , vol.88 , Issue.1 , pp. 17-21
    • Rose, P.G.1    Mossbruger, K.2    Fusco, N.3    Smrekar, M.4    Eaton, S.5    Rodriguez, M.6
  • 36
    • 33746288695 scopus 로고    scopus 로고
    • Cisplatin plus gemcitabine in platinum-refractory ovarian or primary peritoneal cancer: a phase II study of the Gynecologic Oncology Group
    • Brewer C.A., Blessing J.A., Nagourney R.A., Morgan M., and Hanjani P. Cisplatin plus gemcitabine in platinum-refractory ovarian or primary peritoneal cancer: a phase II study of the Gynecologic Oncology Group. Gynecol Oncol 103 2 (2006) 446-450
    • (2006) Gynecol Oncol , vol.103 , Issue.2 , pp. 446-450
    • Brewer, C.A.1    Blessing, J.A.2    Nagourney, R.A.3    Morgan, M.4    Hanjani, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.