Synthesis, antitubercular and antimicrobial activities of some new pyrazoline and isoxazole derivatives

Journal of the Indian Chemical Society

Volumn 84, Issue 11, 2007, Pages 1140-1144

  Vyas, D H ^a   Tala, S D ^a   Dhaduk, M F ^a   Akbari, J D ^a   Joshi, H S ^a  

^a SAURASHTRA UNIVERSITY   (India)

Author keywords

Isoxazoles; Microbial activity; Pyrazolines

Indexed keywords

1 ACETYL 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (2 CHLOROPHENYL) 4,5 DIHYDRO 1H PYRAZOLE; 1 ACETYL 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (2 HYDROXYPHENYL) 4,5 DIHYDRO 1H PYRAZOLE; 1 ACETYL 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (2 NITROPHENYL) 4,5 DIHYDRO 1H PYRAZOLE; 1 ACETYL 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (3 BROMOPHENYL) 4,5 DIHYDRO 1H PYRAZOLE; 1 ACETYL 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (3 NITROPHENYL) 4,5 DIHYDRO 1H PYRAZOLE; 1 ACETYL 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (3 PHENOXYPHENYL) 4,5 DIHYDRO 1H PYRAZOLE; 1 ACETYL 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (4 CHLOROPHENYL) 4,5 DIHYDRO 1H PYRAZOLE; 1 ACETYL 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (4 HYDROXYPHENYL) 4,5 DIHYDRO 1H PYRAZOLE; 1 ACETYL 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (4 METHOXYLPHENYL) 4,5 DIHYDRO 1H PYRAZOLE; 1 ACETYL 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (4 N,N DIMETHYLAMINOPHENYL) 4,5 DIHYDRO 1H PYRAZOLE; 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (2 CHLOROPHENYL)ISOXAZOLE; 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (2 NITROPHENYL)ISOXAZOLE; 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (3 BROMOPHENYL)ISOXAZOLE; 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (3 NITROPHENYL)ISOXAZOLE; 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (3 PHENOXYPHENYL)ISOXAZOLE; 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (4 CHLOROPHENYL)ISOXAZOLE; 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (4 HYDROXYPHENYL)ISOXAZOLE; 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (4 METHOXYPHENYL)ISOXAZOLE; 3 (3,5 DIBROMO 4 METHOXYPHENYL) 5 (4 N,N DIMETHYLPHENYL)ISOXAZOLE; 3 (3,5 DIBROMO 5 METHOXYPHENYL) 5 (2 HYDROXYPHENYL)ISOXAZOLE; ACETIC ACID; AMOXICILLIN; AMPICILLIN; GRISEOFULVIN; HYDROXYLAMINE; ISOXAZOLE DERIVATIVE; NORFLOXACIN; PENICILLIN G; PYRAZOLINE DERIVATIVE; RIFAMPICIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTITUBERCULAR ACTIVITY; ARTICLE; ASPERGILLUS NIGER; BACILLUS MEGATERIUM; BACILLUS SUBTILIS; CONTROLLED STUDY; CYCLIZATION; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; ESCHERICHIA COLI; IN VITRO STUDY; NONHUMAN; POLYMERIZATION; PROTEUS VULGARIS; STRUCTURE ACTIVITY RELATION;

EID: 37449014506     PISSN: 00194522     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. K. S. Nimavat, K. H. Popat and H. S. Joshi, Indian J. Heterocyclic Chem., 2003, 12, 225.
2. B. A. Bhat, K. L. Dhar, S. C. Puri, A. K. Saxena, M. Shanmugavel and G. N. Qazi, Bioorg. Med. Chem. Lett., 2005, 15, 3177.
3. A. A. Bekhit, H. M. Ashour and A. A. Guemei, Arch. Pharm. (Weinheim), 2005, 338, 167.
4. K. D. Shin, M. Y. Lee, D. S. Shin, S. Lee, K. H. Son, S. Koh, Y. K. Paik, B. M. Kwon and D. C. Han, J. Biol. Chem., 2005, 280, 41439.
5. Z. Ozdemir, H. B. Kandilei, B. Gumusel, U. Calis and A. A. Bilgin, Eur. J. Med. Chem., 2007, 42, 373.
6. Mohamed Ashraf Ali, Mohammad Shaharyar and Anees Ahamed Siddiqui, Eur. J. Med. Chem., 2007, 42, 268.
7. G. Ahmad, P. K. Mishra, P. Gupta, P. P. Yadav, P. Tiwari, A. K. Tamrakar, A. K. Srivastava and R. Maurya, Bioorg. Med. Chem. Lett., 2006, 16, 2139.
8. B. L. Deng, M. D. Cullen, Z. Zhou, T. L. Hartman, R. W. Buckheit (Jr.), C. Pannecouque, E. De Clercq, P. E. Fanwick and M. Cushman, Bioorg. Med. Chem., 2006, 14, 2366.
9. P. T. Chovatia, J. D. Akbari, P. K. Kachhadia, P. D. Zalavadia and H. S. Joshi, J. Serb. Chemical Soc., 2007, 71, 713.
10. K. H. Popat, K. S. Nimavat, V. V. Kachhadia and H. S. Joshi, J. Indian Chem. Soc., 2003, 80, 707.
11. "The Antimicrobial Susceptibility Test : Principle and Practices", eds. A. L. Barry, Lea and Febiger, Philadelphia Pa, USA, 1976, p. 180;
12. Biol Abstr., 1976, 64, 25183.