Decreased expression of transporters reduces folate uptake across renal absorptive surfaces in experimental alcoholism

Journal of Membrane Biology

Volumn 220, Issue 1-3, 2007, Pages 69-77

  Hamid, Abid ^a   Kaur, Jyotdeep ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Alcoholism; Basolateral; Brush border; Folate binding protein; Reduced folate carrier; Transport

Indexed keywords

FOLATE BINDING PROTEIN; FOLIC ACID; PROTEIN ANTIBODY; REDUCED FOLATE CARRIER;

ABSORPTION; ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASOLATERAL MEMBRANE; CONTROLLED STUDY; DOWN REGULATION; FOLIC ACID DEFICIENCY; KIDNEY TUBULE ABSORPTION; MALE; NONHUMAN; PH; PROTEIN EXPRESSION; RAT; URINARY EXCRETION;

ALCOHOLISM; ANIMALS; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CARRIER PROTEINS; ETHANOL; FOLIC ACID; FOLIC ACID DEFICIENCY; HYDROGEN-ION CONCENTRATION; KIDNEY; KINETICS; MALE; MEMBRANE TRANSPORT PROTEINS; MICROVILLI; OSMOLAR CONCENTRATION; RATS; RATS, WISTAR; RECEPTORS, CELL SURFACE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

RATTUS NORVEGICUS;

EID: 37449012436     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-007-9075-3     Document Type: Article

References (28)

1. Agnieszka B, Patrycja W, Malgorzata B (2000) Cellular aspects of folate and antifolate membrane transport. Acta Biochim Pol 47:735-749
2. Birn H, Nielsen S, Christensen EI (1997) Internalization and apical-to-basolateral transport of folate in rat kidney proximal tubule. Am J Physiol 272:F70-F78
3. Burtis CA, Ashwood ER, Tietz NW (1994) Textbook of clinical chemistry, 2nd ed. Saunders, Philadelphia
4. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
5. Dudeja PK, Torania SA, Said HM (1997) Evidence for the existence of a carrier-mediated folate uptake mechanism in human colonic luminal membranes. Am J Physiol 272:G1408-G1415
6. Dudeja PK, Kode A, Alnounou M, Tyagi S, Torania S, Subramanian VS, Said HM (2001) Mechanism of folate transport across the human colonic basolateral membrane. Am J Physiol 281:G54-G60
7. Eisenga BH, Collins TD, McMartin KE (1989) Differential effects of acute ethanol on urinary excretion of folate derivatives in the rat. J Pharmacol Exp Ther 248:916-922
8. Elwood PC, Deutsch JC, Kolhouse JF (1991) The conversion of the human membrane-associated folate binding protein (folate receptor) to the soluble folate binding protein by a membrane-associated metalloproteases. J Biol Chem 266:2346-2353
9. Halsted CH (2001) Lifestyle effects on homocysteine and an alcohol paradox. Am J Clin Nutr 73:501-502
10. Halsted CH, Villanueva JA, Devlin AM, Niemela O, Parkkila S, Garrow TA, Wallock LM, Shigenaga MK, Melnyk S, James SJ (2002) Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig. Proc Natl Acad Sci USA 99:10072-10077
11. Hamid A, Kaur J (2005) Kinetic characteristics of folate binding to rat renal brush border membrane in chronic alcoholism. Mol Cell Biochem 280:219-225
12. Hamid A, Kaur J (2006) Chronic alcoholism alters the transport characteristics of folate in rat renal brush border membrane. Alcohol 38:59-66
13. Kessler M, Acuto O, Storelli C, Murer H, Muller M, Samenza G (1978) A modified procedure for the rapid preparation of efficiently transporting vesicles from small intestinal brush border membranes. Their use in investigating some properties of d-glucose and choline transport. Biochim Biophys Acta 506:136-154
14. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
15. Masuda S, Takeuchi A, Saito H, Hashimoto Y, Inui K (1999) Functional analysis of rat renal organic anion transporter OAT-K1: bidirectional methotrexate transport in apical membrane. FEBS Lett 459:128-132
16. McMartin KE, Shiao CQ, Collins TD, Redetzki HM (1985) Acute ethanol ingestion by humans and subacute treatment of rats increased urinary folate excretion. Alcohol 2:473-477
17. McMartin KE, Collins TD, Eisenga BH, Fortney T, Bates WR, Bairnsfather L (1989) Effects of chronic ethanol and diet treatment on urinary folate excretion and development of folate deficiency in the rat. J Nutr 119:1490-1497
18. Muldoon RT, McMartin KE (1994) Ethanol acutely impairs the renal conservation of 5-methyltetrahydrofolate in the isolated perfused rat kidney. Alcohol Clin Exp Res 18:333-339
19. Sabharanjak S, Mayor S (2004) Folate receptor endocytosis and trafficking. Adv Drug Deliv Rev 56:1099-1109
20. Said HM (2004) Recent advances in carrier-mediated intestinal absorption of water-soluble vitamins. Annu Rev Physiol 66:419-446
21. Said HM, Redha R (1987) A carrier-mediated transport for folate in basolateral membrane vesicles of rat small intestine. Biochem J 247:141-146
22. Saito H, Masuda S, Inui K (1996) Cloning and functional characterization of a novel rat organic anion transporter mediating basolateral uptake of methotrexate in the kidney. J Biol Chem 271:20719-20725
23. Scalera V, Storelli C, Storelli-Joss C, Haase W, Murer H (1980) A simple and fast method for the isolation of basolateral membrane from rat small-intestinal epithelial cells. Biochem J 186:177-181
24. Sikka PK, McMartin KE (1998) Determination of folate transport pathways in cultured rat proximal tubule cells. Chem Biol Interact 114:15-31
25. Towbin H, Staehelin T, Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76:4350-4354
26. Villanueva J, Ling EH, Chandler CJ, Halsted CH (1998) Membrane and tissue distribution of folate binding protein in pig. Am J Physiol 275:R1503-R1510
27. Villanueva J, Devlin AM, Halsted CH (2001) Reduced folate carrier: tissue distribution and effects of chronic ethanol intake in the micropig. Alcohol Clin Exp Res 25:415-420
28. Wang Y, Zhao R, Russell RG, Goldman ID (2001) Localization of the murine reduced folate carrier as assessed by immunohistochemical analysis. Biochim Biophys Acta 1513:49-54