Lycopus europaeus (Gypsywort): Effects on the thyroidal parameters and symptoms associated with thyroid function

Phytomedicine

Volumn 15, Issue 1-2, 2008, Pages 16-22

  Beer, A M ^a   Wiebelitz, K R ^a   Schmidt Gayk, H ^b  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b Limbach Laboratory   (Germany)

Author keywords

Hyperthyroidism; Lycopus europaeus (Gypsywort); Thyroid function; Urinary T3 T4 excretion

Indexed keywords

LIOTHYRONINE; LYCOPUS EUROPAEUS EXTRACT; THYROXINE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; FOLLOW UP; GERMANY; GLOMERULUS; HUMAN; HYPERTHYROIDISM; KIDNEY TUBULE ABSORPTION; LYCOPUS; LYCOPUS EUROPAEUS; MALE; OPEN STUDY; PARAMETER; PRIORITY JOURNAL; SYMPTOM; TACHYCARDIA; THYROID FUNCTION; THYROTROPIN BLOOD LEVEL; URINARY EXCRETION;

BODY MASS INDEX; BODY WEIGHT; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; HEART RATE; HUMANS; HYPERTHYROIDISM; LYCOPUS; MALE; MIDDLE AGED; PATIENT COMPLIANCE; PHYTOTHERAPY; PLANT PREPARATIONS; PROSPECTIVE STUDIES; THYROID FUNCTION TESTS; THYROTROPIN; THYROXINE; TRIIODOTHYRONINE;

LYCOPUS EUROPAEUS;

EID: 37448999202     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2007.11.001     Document Type: Article

References (30)

1. Auf'mkolk M., Ingbar J.C., Amir S.M., Winterhoff H., Sourgens H., Hesch R.D., et al. The active principles of plant extracts with antithyrotropic activity, oxidation products of derivatives of 3,4-dihydroxycinnamic acid. Endocrinology 116 (1985) 1677-1686
2. Auf'mkolk M., Ingbar J.C., Kubota K., Amir S.M., and Ingbar S.H. Extracts and auto-oxidized constituents of certain plants inhibit the receptor-binding and the biological activity of Graves' immunoglobulins. Endocrinology 116 (1985) 1687-1693
3. Baisier W.V., Hertoghe J., and Eeckhaut W. Thyroid insuficiency. Is TSH measurement the only diagnostic tool?. J. Nutr. Environ. Med. 10 (2000) 105-113
4. Beer A.M., Ostermann T., and Matthiessen P.F. Evaluation stationärer Naturheilkunde-Das Blankensteiner Modell. Teil I, Patientenklientel und therapeutische Konzepte. Forsch. Komplementärmedizin Klass. Naturheilkd 8 (2000) 6-13
5. ®N und Tabletten mit Lycopus-Extrakt auf die spontane kontraktile Aktivität der glatten Muskulatur. In Reuter H.D. Phytopharmaka und Phytotherapie 2004 - Forschung und Praxis. Z. Phytother. 25 (2004) 300
6. Bullinger M., and Kirchberger I. SF-36 Fragebogen zum Gesundheitszustand. Handanweisung (1998), Hogrefe, Göttingen
7. Burke C.W., and Shakespear R.A. Triiodothyronine and thyroxine in urine. II. Renal handling, and effect of urinary protein. J. Clin. Endocrinol. Metab. 42 (1976) 504-513
8. Friedman M. The use of ranks to avoid the assumption of normality implicit in the analysis of variance. J. Am. Statist. Assoc. 32 (1937) 675-701
9. Hiller E., and Deglmann H. Influence of Lycopus europaeus extracts on distribution of iodine in human serum. Arzneimittelforschung 5 (1955) 465-470
10. Hoerhammer L., Wagner H., and Schilcher H. On the knowledge of the constituents of Lycopus europaeus. 1. On the constituents of medicinal plants with hormone and antihormone like action. Arzneimittelforschung 12 (1962) 1-7
11. Hussein A.A., and Rodriguez B. Isopimarane diterpenoids from Lycopus europaeus. J. Nat. Prod. 63 (2000) 419-421
12. Karl J. Neue Therapiekonzepte für die Praxis der Naturheilkunde (1995), Pflaum, München p. 304
13. Kemper F., and Loeser A. Lycopus - new aspects of actions against hypophyseal hormones. Acta Endocrinol. (Kbh) 38 (1961) 200-206
14. Köhler, S., Tran, C.T., Funk, P., Niestroy, M., Kieser, M., 2004. Allevation of mastodynia and the pre-menstrual syndrome with an extract of Lycopus europaeus (Thyreogutt). Abstract in: Phytopharmaka und Phytotherapie, Berlin, p. 50.
15. Kommission, E., 1990. BAnz-Nr. 22a vom 01.02.90.
16. Kruskal W.H., and Wallis W.A. Use of ranks in one-criterion variance analysis. J. Am. Statist. Assoc. 48 (1953) 907-911
17. Mann H.B., and Whitney D.R. On a test of whether one of two random variables is stochastically larger than the other. Ann. Math. Statist. (1947) 1850-1860
18. Orden I., Pie J., Juste M.G., Marsella J.A., and Blasco C. Thyroxine in unextracted urine. Acta Endocrinol. (Copenh) 114 (1987) 503-508
19. Ostermann T., Beer A.M., and Matthiessen P.F. Evaluation stationärer Naturheilkunde-Das Blankensteiner Modell. Teil II, Outcome Parameter im zeitlichen Verlauf und Effektstärken. Forsch. Komplementärmed. Klass. Naturheilkd. 9 (2002) 269-276
20. Rollemann E.J., Hennemann G., van Toor H., Schoemakers Ch.H.H., Krenning E.P., and de Jong M. Changes in renal tri-iodothyronine and thyroxine handling during fasting. Eur. J. Endocrinol. 142 (2000) 125-130
21. Rompel A., Fischer H., Meiwes D., Buldt-Karentzopoulos K., Magrini A., Eicken C., et al. Substrate specificity of catechol oxidase from Lycopus europaeus and characterization of the bioproducts of enzymic caffeic acid oxidation. FEBS Lett. 445 (1999) 103-110
22. Scheck R., and Biller A. Wolfstrappkraut-eine Alternative zu synthetischen Thyreostatika ?. Naturamed 15 (2000) 31-36
23. Schilcher H., and Kammerer S. Leitfaden Phytotherapie. 2. Aufl (2003), Urban & Fischer Verlag, München, Jena p. 247
24. In: Thomas L. (Ed). Labor und Diagnose. 4. Aufl (1992), Medizinische Verlagsgesellschaft, Marburg, Frankfurt/Main p. 1260
25. Voigt K. Endokrines system. In: Klinke R., and Silbernagel S. (Eds). Lehrbuch der Physiologie. 2. Aufl (1996), Georg Thieme Verlag, Stuttgart, New York 473
26. von Zeersen D., Koeller D.M., and Rey E.R. Die Befindlichkeits-Skala (Bf-S) - ein einfaches Instrument zur Objektivierung von Befindlichkeitsstörungen, insbesondere im Rahmen von Längsschnittuntersuchungen. A scale for the objective evaluation of the state of subjective well-being as a method for longitudinal studies. Arzneimittel-Forschung 20 (1970) 915-918
27. Vonhoff C., Baumgartner A., Hegger M., Korte B., Biller A., and Winterhoff H. Extract of Lycopus europaeus L. reduces cardiac signs of hyperthyroidism in rats. Life Sci. 78 (2006) 1063-1070
28. Wagner H., Hoerhammer L., and Frank U. Lithospermic acid, the antihormonally active principle of Lycopus europaeus L. and Symphytum officinale. 3. Ingredients of medicinal plants with hormonal and antihormonal-like effect. Arzneimittelforschung 20 (1970) 705-713
29. Wilcoxon F., Katti S.K., and Wilcox R.A. Critical Values and Probability Levels for the Wilcoxon Rank Sum Test and the Wilcoxon Signed Rank Test (1963), Lederle Laboratories, Division Amer. Cyanid Company, Pearl River, New York
30. Winterhoff H., Gumbinger H.G., Vahlensieck U., Kemper F.H., Schmitz H., and Behnke B. Endocrine effects of Lycopus europaeus L. following oral application. Arzneimittel-Forschung 44 1 (1994) 41-45