Effects of different concentrations of monensin on the contractility changes of Guinea-pig papillary muscle

Turkish Journal of Veterinary and Animal Sciences

Volumn 22, Issue 2, 1998, Pages 145-149

  Meral, Ismail ^a  

^a YUZUNCU YIL UNIVERSITY   (Turkey)

Author keywords

Calcium; Guinea pig; Monensin; Papillary muscle; Positive inotrope

Indexed keywords

EID: 3743132166     PISSN: 13000128     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Mollenhauer, H.H., More. J.D. and Rowe, D.L: Alteration of intracellular traffic by monensin: mechanism, specificity and relationship to toxicity. Brachium. Trophy. Acta. 1990; 1031, 225.
2. Shumard, R.F., and Callender, M.E.: Effectiveness of monensin against experimental injections of coccidia in chickens. Proc. 18th Western Poultry Disease Conference, Davis. 1969; CA, 20.
3. Bergstrom, R.C. and Maki, L.R.: Effect of monensin in young crossbred lambs with naturally occurring coccidiosis. J. Am. Vet. Med. Assoc, 1978; 165, 288.
4. Fitzgerald, P.R.: Efficacy of monensin against bovine coccidiosis in young Holstein-Friesian calves. J. Protozool. 1973; 20, 121.
5. Richardson, L.F., Raun, A.P., Potter, El., Cooley, C.O. and Rathmatiher, R,P.: Effects of monensin on ruminai fermentation in vitro and in vivo. J.An.Sci. 1974; 39, 250.
6. Whitlock, R.H., White, N.A., Rowlond, G.N. and Plue, R.: Monensin toxicosis in horses: Clinical manifestations Proc. 24th Ann. Conv. Am. Assoc. Equine Pract, St Louis, 1978; MO: 473-486.
7. Pressman, B.C.: Biological applications of ionophores. Ann. Rev. Biochem. 1976; 45, 501-529.
8. Sutko, J.L.,Besch, H.R., Bailey, J.C., Zimmerman, G., and Watanabe, A.M. Direct effect of the monovalent cation ionophores monensin and nigericin on myocardium. J. Pharmacol. Exp. Ther. 1977;685-700.
9. Shlafer, M. and Kane, P.: Subcellular actions and potential adverse cardiac effects of the cardiotonic ionophore monensin. J. Pharmacol. Exp. Ther. 1980; 214, 567-573.
10. Tsuchida, K. and and Otomo, S.: Electrophysiological effects of monensin, a sodium ionophore, on cardiac, purkinje fibers. Eur. J. Pharmacol. 1990; 190, 313-320.
11. Snedecor, G.W. and Cochran, W.G.: Statistical methods. Eight edition. 1989;227.
12. Orchard, C.: The effect of acidosis on excitation-contraction coupling in isolated ferret heart muscle. Mol. Cell. Biochem. 1989,89, 169-173.
13. Blanchard, E.M. and Solaro, R.J.: Inhibition of the activation and troponin calcium binding of dog cardiac myofibriles by acidic pH. Circ. Res. 1984;55,382-391.
14. Poole-Wilson, P.A.: Regulation of intracellular pH in the myocardium; relevance to pathology, Mol, Cell. Biochem. 1989; 151-155.
15. Honore, E., Adamantidis, M.M., Dupuis, B.A., Challice, C.E. and Guilbavit, P.: Calcium channels and excitation contraction coupling in cardiac cells. II. A pharmacological study of the biphasic contraction in guinea-pig papillary muscles. Can. J. Physiol. 1987;65, 1832-1839.
16. Honore, E., Adamantidis, M.M., Dupuis, B.A., Challice, C.E. and Guilbault. P.: Calcium channels and excitation-contraction coupling in cardiac cells. I. Two components of contraction in guinea-pig papillary muscles. Can. J. Physiol. 1987; 65, 1832-1839.
17. Barry, W.H., and Bridge, JHB.: intracellular calcium homeostasis in cardiac myocytes. Circulation. 1993;87,6. 1806-1815.
18. Sauders, W.B.: Textbook of physiology. 1989; 2, 21st edition. 820.